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Research ArticleSpecial Section on Natural Products: Experimental Approaches to Elucidate Disposition Mechanisms and Predict Pharmacokinetic Drug Interactions

Influence of Zuojin Pill on the Metabolism of Venlafaxine in Vitro and in Rats and Associated Herb-Drug Interaction

Yue Li, Juan Li, Dongmin Yan, Qian Wang, Jingyi Jin, Bo Tan and Furong Qiu
Drug Metabolism and Disposition October 2020, 48 (10) 1044-1052; DOI: https://doi.org/10.1124/dmd.120.000048
Yue Li
Laboratory of Clinical Pharmacokinetics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China (Y.L., J.L., D.Y., Q.W., J.J., B.T., F.Q.) and Department of Pharmacy, Pudong New Area People’s Hospital, Shanghai, China (J.L.)
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Juan Li
Laboratory of Clinical Pharmacokinetics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China (Y.L., J.L., D.Y., Q.W., J.J., B.T., F.Q.) and Department of Pharmacy, Pudong New Area People’s Hospital, Shanghai, China (J.L.)
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Dongmin Yan
Laboratory of Clinical Pharmacokinetics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China (Y.L., J.L., D.Y., Q.W., J.J., B.T., F.Q.) and Department of Pharmacy, Pudong New Area People’s Hospital, Shanghai, China (J.L.)
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Qian Wang
Laboratory of Clinical Pharmacokinetics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China (Y.L., J.L., D.Y., Q.W., J.J., B.T., F.Q.) and Department of Pharmacy, Pudong New Area People’s Hospital, Shanghai, China (J.L.)
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Jingyi Jin
Laboratory of Clinical Pharmacokinetics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China (Y.L., J.L., D.Y., Q.W., J.J., B.T., F.Q.) and Department of Pharmacy, Pudong New Area People’s Hospital, Shanghai, China (J.L.)
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Bo Tan
Laboratory of Clinical Pharmacokinetics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China (Y.L., J.L., D.Y., Q.W., J.J., B.T., F.Q.) and Department of Pharmacy, Pudong New Area People’s Hospital, Shanghai, China (J.L.)
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  • For correspondence: tbot@163.com
Furong Qiu
Laboratory of Clinical Pharmacokinetics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China (Y.L., J.L., D.Y., Q.W., J.J., B.T., F.Q.) and Department of Pharmacy, Pudong New Area People’s Hospital, Shanghai, China (J.L.)
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  • For correspondence: furong_qiu@126.com
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Article Information

vol. 48 no. 10 1044-1052
DOI 
https://doi.org/10.1124/dmd.120.000048
PubMed 
32561594

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 26, 2020
  • Accepted June 11, 2020
  • Published online September 22, 2020.

Article Versions

  • Earlier version (June 19, 2020 - 01:21).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2020 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yue Li,
  2. Juan Li,
  3. Dongmin Yan,
  4. Qian Wang,
  5. Jingyi Jin,
  6. Bo Tan⇑, and
  7. Furong Qiu⇑
  1. Laboratory of Clinical Pharmacokinetics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China (Y.L., J.L., D.Y., Q.W., J.J., B.T., F.Q.) and Department of Pharmacy, Pudong New Area People’s Hospital, Shanghai, China (J.L.)
  1. Address correspondence to:
    Bo Tan, Laboratory of Clinical Pharmacokinetics, Shuguang Hospital Affiliated to Shanghai University of TCM, 528 Zhangheng Rd., Shanghai 201203, China. E-mail: tbot{at}163.com; or
  2. Furong Qiu, Laboratory of Clinical Pharmacokinetics, Shuguang Hospital Affiliated to Shanghai University of TCM, 528 Zhangheng Rd., Shanghai 201203, China. E-mail: furong_qiu{at}126.com
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Drug Metabolism and Disposition: 48 (10)
Drug Metabolism and Disposition
Vol. 48, Issue 10
1 Oct 2020
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Research ArticleSpecial Section on Natural Products: Experimental Approaches to Elucidate Disposition Mechanisms and Predict Pharmacokinetic Drug Interactions

Influence of Zuojin Pill on Venlafaxine

Yue Li, Juan Li, Dongmin Yan, Qian Wang, Jingyi Jin, Bo Tan and Furong Qiu
Drug Metabolism and Disposition October 1, 2020, 48 (10) 1044-1052; DOI: https://doi.org/10.1124/dmd.120.000048

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Research ArticleSpecial Section on Natural Products: Experimental Approaches to Elucidate Disposition Mechanisms and Predict Pharmacokinetic Drug Interactions

Influence of Zuojin Pill on Venlafaxine

Yue Li, Juan Li, Dongmin Yan, Qian Wang, Jingyi Jin, Bo Tan and Furong Qiu
Drug Metabolism and Disposition October 1, 2020, 48 (10) 1044-1052; DOI: https://doi.org/10.1124/dmd.120.000048
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