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Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate In Vitro Tools and Clearance Prediction

Kenichi Umehara, Carina Cantrill, Matthias Beat Wittwer, Elisa Di Lenarda, Florian Klammers, Aynur Ekiciler, Neil Parrott, Stephen Fowler and Mohammed Ullah
Drug Metabolism and Disposition October 2020, 48 (10) 849-860; DOI: https://doi.org/10.1124/dmd.120.000133
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In Vitro Assays for CLh Prediction with ECCS-Based IVIVE

Kenichi Umehara, Carina Cantrill, Matthias Beat Wittwer, Elisa Di Lenarda, Florian Klammers, Aynur Ekiciler, Neil Parrott, Stephen Fowler and Mohammed Ullah
Drug Metabolism and Disposition October 1, 2020, 48 (10) 849-860; DOI: https://doi.org/10.1124/dmd.120.000133
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