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Index by author

November 01, 2020; Volume 48,Issue 11

B

  1. Balsitis, Scott

    1. Characterization of Seasonal Pharmacokinetic Variability in Woodchucks
      Jim Zheng, Scott Balsitis, Rex Santos, Bill J. Smith and Raju Subramanian
      Drug Metabolism and Disposition November 2020, 48 (11) 1199-1209; DOI: https://doi.org/10.1124/dmd.120.000140

  2. Baudy, Andreas

    1. A Two-Tiered In Vitro Approach to De-Risk Drug Candidates for Potential Bile Salt Export Pump Inhibition Liabilities in Drug Discovery
      Michael J. Hafey, Robert Houle, Keith Q. Tanis, Ian Knemeyer, Jackie Shang, Qing Chen, Andreas Baudy, James Monroe, Frank D. Sistare and Raymond Evers
      Drug Metabolism and Disposition November 2020, 48 (11) 1147-1160; DOI: https://doi.org/10.1124/dmd.120.000086

  3. Beckers, Claire

    1. (–)-<em>N</em>-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-<em>N</em>-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      (–)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
      Drug Metabolism and Disposition November 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089

  4. Bolleddula, Jayaprakasam

    1. Pharmacokinetics and Catabolism of [3H]TAK-164, a Guanylyl Cyclase C Targeted Antibody-Drug Conjugate
      Jayaprakasam Bolleddula, Abhi Shah, Mohammad Shadid, Afrand Kamali, Michael D. Smith and Swapan K. Chowdhury
      Drug Metabolism and Disposition November 2020, 48 (11) 1239-1245; DOI: https://doi.org/10.1124/dmd.120.000194

  5. Bonnaillie, Pierre

    1. (–)-<em>N</em>-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-<em>N</em>-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      (–)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
      Drug Metabolism and Disposition November 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089

C

  1. Cai, Hao

    1. Open Access
      Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti–Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
      Hao Cai, Victor Yip, M. Violet Lee, Sylvia Wong, Ola Saad, Shuguang Ma, Nina Ljumanovic, S. Cyrus Khojasteh, Amrita V. Kamath and Ben-Quan Shen
      Drug Metabolism and Disposition November 2020, 48 (11) 1161-1168; DOI: https://doi.org/10.1124/dmd.120.000092

  2. Chanteux, Hugues

    1. (–)-<em>N</em>-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-<em>N</em>-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      (–)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
      Drug Metabolism and Disposition November 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089

  3. Chapron, Brian D.

    1. The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites
      Brian D. Chapron, Jean C. Dinh, Paul C. Toren, Andrea Gaedigk and J. Steven Leeder
      Drug Metabolism and Disposition November 2020, 48 (11) 1113-1120; DOI: https://doi.org/10.1124/dmd.120.000188

  4. Chen, Ang

    1. Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Jian Lu, Ang Chen, Xinrun Ma, Xuyang Shang, Yuanjin Zhang, Yuanqing Guo, Mingyao Liu and Xin Wang
      Drug Metabolism and Disposition November 2020, 48 (11) 1129-1136; DOI: https://doi.org/10.1124/dmd.120.000114

  5. Chen, Qing

    1. A Two-Tiered In Vitro Approach to De-Risk Drug Candidates for Potential Bile Salt Export Pump Inhibition Liabilities in Drug Discovery
      Michael J. Hafey, Robert Houle, Keith Q. Tanis, Ian Knemeyer, Jackie Shang, Qing Chen, Andreas Baudy, James Monroe, Frank D. Sistare and Raymond Evers
      Drug Metabolism and Disposition November 2020, 48 (11) 1147-1160; DOI: https://doi.org/10.1124/dmd.120.000086

  6. Chowdhury, Swapan K.

    1. Pharmacokinetics and Catabolism of [3H]TAK-164, a Guanylyl Cyclase C Targeted Antibody-Drug Conjugate
      Jayaprakasam Bolleddula, Abhi Shah, Mohammad Shadid, Afrand Kamali, Michael D. Smith and Swapan K. Chowdhury
      Drug Metabolism and Disposition November 2020, 48 (11) 1239-1245; DOI: https://doi.org/10.1124/dmd.120.000194

  7. Cuypers, Marie-Lynn

    1. (–)-<em>N</em>-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-<em>N</em>-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      (–)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
      Drug Metabolism and Disposition November 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089

D

  1. Davies, Mari

    1. Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Mari Davies, Prabha Peramuhendige, Lloyd King, Melanie Golding, Apoorva Kotian, Mark Penney, Syeda Shah and Nenad Manevski
      Drug Metabolism and Disposition November 2020, 48 (11) 1169-1182; DOI: https://doi.org/10.1124/dmd.120.000111

  2. Delatour, Claude

    1. (–)-<em>N</em>-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-<em>N</em>-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      (–)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
      Drug Metabolism and Disposition November 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089

  3. Dell’Aiera, Sylvie

    1. (–)-<em>N</em>-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-<em>N</em>-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      (–)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
      Drug Metabolism and Disposition November 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089

  4. De Sousa Mendes, Mailys

    1. A Laboratory-Specific Scaling Factor to Predict the In Vivo Human Clearance of Aldehyde Oxidase Substrates
      Mailys De Sousa Mendes, Alexandra L. Orton, Helen E. Humphries, Barry Jones, Iain Gardner, Sibylle Neuhoff and Venkatesh Pilla Reddy
      Drug Metabolism and Disposition November 2020, 48 (11) 1231-1238; DOI: https://doi.org/10.1124/dmd.120.000082

  5. Dinh, Jean C.

    1. The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites
      Brian D. Chapron, Jean C. Dinh, Paul C. Toren, Andrea Gaedigk and J. Steven Leeder
      Drug Metabolism and Disposition November 2020, 48 (11) 1113-1120; DOI: https://doi.org/10.1124/dmd.120.000188

E

  1. Evers, Raymond

    1. A Two-Tiered In Vitro Approach to De-Risk Drug Candidates for Potential Bile Salt Export Pump Inhibition Liabilities in Drug Discovery
      Michael J. Hafey, Robert Houle, Keith Q. Tanis, Ian Knemeyer, Jackie Shang, Qing Chen, Andreas Baudy, James Monroe, Frank D. Sistare and Raymond Evers
      Drug Metabolism and Disposition November 2020, 48 (11) 1147-1160; DOI: https://doi.org/10.1124/dmd.120.000086

G

  1. Gaedigk, Andrea

    1. The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites
      Brian D. Chapron, Jean C. Dinh, Paul C. Toren, Andrea Gaedigk and J. Steven Leeder
      Drug Metabolism and Disposition November 2020, 48 (11) 1113-1120; DOI: https://doi.org/10.1124/dmd.120.000188

  2. Gardner, Iain

    1. A Laboratory-Specific Scaling Factor to Predict the In Vivo Human Clearance of Aldehyde Oxidase Substrates
      Mailys De Sousa Mendes, Alexandra L. Orton, Helen E. Humphries, Barry Jones, Iain Gardner, Sibylle Neuhoff and Venkatesh Pilla Reddy
      Drug Metabolism and Disposition November 2020, 48 (11) 1231-1238; DOI: https://doi.org/10.1124/dmd.120.000082

  3. Gillent, Eric

    1. (–)-<em>N</em>-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-<em>N</em>-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      (–)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
      Drug Metabolism and Disposition November 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089

  4. Golding, Melanie

    1. Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Mari Davies, Prabha Peramuhendige, Lloyd King, Melanie Golding, Apoorva Kotian, Mark Penney, Syeda Shah and Nenad Manevski
      Drug Metabolism and Disposition November 2020, 48 (11) 1169-1182; DOI: https://doi.org/10.1124/dmd.120.000111

  5. Gormsen, Lars C.

    1. Successful Prediction of Positron Emission Tomography–Imaged Metformin Hepatic Uptake Clearance in Humans Using the Quantitative Proteomics–Informed Relative Expression Factor Approach
      Madhav Sachar, Vineet Kumar, Lars C. Gormsen, Ole Lajord Munk and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2020, 48 (11) 1210-1216; DOI: https://doi.org/10.1124/dmd.120.000156

  6. Guo, Yuanqing

    1. Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Jian Lu, Ang Chen, Xinrun Ma, Xuyang Shang, Yuanjin Zhang, Yuanqing Guo, Mingyao Liu and Xin Wang
      Drug Metabolism and Disposition November 2020, 48 (11) 1129-1136; DOI: https://doi.org/10.1124/dmd.120.000114

H

  1. Hafey, Michael J.

    1. A Two-Tiered In Vitro Approach to De-Risk Drug Candidates for Potential Bile Salt Export Pump Inhibition Liabilities in Drug Discovery
      Michael J. Hafey, Robert Houle, Keith Q. Tanis, Ian Knemeyer, Jackie Shang, Qing Chen, Andreas Baudy, James Monroe, Frank D. Sistare and Raymond Evers
      Drug Metabolism and Disposition November 2020, 48 (11) 1147-1160; DOI: https://doi.org/10.1124/dmd.120.000086

  2. Hagenbuch, Bruno

    1. Functional Consequences of Pravastatin Isomerization on OATP1B1-Mediated Transport
      Jonathan B. Wagner, Melissa Ruggiero, J. Steven Leeder and Bruno Hagenbuch
      Drug Metabolism and Disposition November 2020, 48 (11) 1192-1198; DOI: https://doi.org/10.1124/dmd.120.000122

  3. Harlfinger, Stephanie

    1. Evaluation of the Disconnect between Hepatocyte and Microsome Intrinsic Clearance and In Vitro In Vivo Extrapolation Performance
      Beth Williamson, Stephanie Harlfinger and Dermot F. McGinnity
      Drug Metabolism and Disposition November 2020, 48 (11) 1137-1146; DOI: https://doi.org/10.1124/dmd.120.000131

  4. Horne, Lloyd P.

    1. Exposure of Rats to Multiple Oral Doses of Dichloroacetate Results in Upregulation of Hepatic Glutathione Transferases and NAD(P)H Dehydrogenase [Quinone] 1
      Edwin J. Squirewell, Ricky Mareus, Lloyd P. Horne, Peter W. Stacpoole and Margaret O. James
      Drug Metabolism and Disposition November 2020, 48 (11) 1224-1230; DOI: https://doi.org/10.1124/dmd.120.000143
    2. Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats
      Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats
      Edwin J. Squirewell, Marci G. Smeltz, Laura Rowland-Faux, Lloyd P. Horne, Peter W. Stacpoole and Margaret O. James
      Drug Metabolism and Disposition November 2020, 48 (11) 1217-1223; DOI: https://doi.org/10.1124/dmd.120.000142

  5. Houle, Robert

    1. A Two-Tiered In Vitro Approach to De-Risk Drug Candidates for Potential Bile Salt Export Pump Inhibition Liabilities in Drug Discovery
      Michael J. Hafey, Robert Houle, Keith Q. Tanis, Ian Knemeyer, Jackie Shang, Qing Chen, Andreas Baudy, James Monroe, Frank D. Sistare and Raymond Evers
      Drug Metabolism and Disposition November 2020, 48 (11) 1147-1160; DOI: https://doi.org/10.1124/dmd.120.000086

  6. Humphries, Helen E.

    1. A Laboratory-Specific Scaling Factor to Predict the In Vivo Human Clearance of Aldehyde Oxidase Substrates
      Mailys De Sousa Mendes, Alexandra L. Orton, Helen E. Humphries, Barry Jones, Iain Gardner, Sibylle Neuhoff and Venkatesh Pilla Reddy
      Drug Metabolism and Disposition November 2020, 48 (11) 1231-1238; DOI: https://doi.org/10.1124/dmd.120.000082

J

  1. James, Margaret O.

    1. Exposure of Rats to Multiple Oral Doses of Dichloroacetate Results in Upregulation of Hepatic Glutathione Transferases and NAD(P)H Dehydrogenase [Quinone] 1
      Edwin J. Squirewell, Ricky Mareus, Lloyd P. Horne, Peter W. Stacpoole and Margaret O. James
      Drug Metabolism and Disposition November 2020, 48 (11) 1224-1230; DOI: https://doi.org/10.1124/dmd.120.000143
    2. Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats
      Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats
      Edwin J. Squirewell, Marci G. Smeltz, Laura Rowland-Faux, Lloyd P. Horne, Peter W. Stacpoole and Margaret O. James
      Drug Metabolism and Disposition November 2020, 48 (11) 1217-1223; DOI: https://doi.org/10.1124/dmd.120.000142

  2. Jones, Barry

    1. A Laboratory-Specific Scaling Factor to Predict the In Vivo Human Clearance of Aldehyde Oxidase Substrates
      Mailys De Sousa Mendes, Alexandra L. Orton, Helen E. Humphries, Barry Jones, Iain Gardner, Sibylle Neuhoff and Venkatesh Pilla Reddy
      Drug Metabolism and Disposition November 2020, 48 (11) 1231-1238; DOI: https://doi.org/10.1124/dmd.120.000082

K

  1. Kamali, Afrand

    1. Pharmacokinetics and Catabolism of [3H]TAK-164, a Guanylyl Cyclase C Targeted Antibody-Drug Conjugate
      Jayaprakasam Bolleddula, Abhi Shah, Mohammad Shadid, Afrand Kamali, Michael D. Smith and Swapan K. Chowdhury
      Drug Metabolism and Disposition November 2020, 48 (11) 1239-1245; DOI: https://doi.org/10.1124/dmd.120.000194

  2. Kamath, Amrita V.

    1. Open Access
      Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti–Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
      Hao Cai, Victor Yip, M. Violet Lee, Sylvia Wong, Ola Saad, Shuguang Ma, Nina Ljumanovic, S. Cyrus Khojasteh, Amrita V. Kamath and Ben-Quan Shen
      Drug Metabolism and Disposition November 2020, 48 (11) 1161-1168; DOI: https://doi.org/10.1124/dmd.120.000092

  3. Katayama, Kazuhide

    1. Impact of P-Glycoprotein–Mediated Active Efflux on Drug Distribution into Lumbar Cerebrospinal Fluid in Nonhuman Primates
      Impact of P-Glycoprotein–Mediated Active Efflux on Drug Distribution into Lumbar Cerebrospinal Fluid in Nonhuman Primates
      Yoko Nagaya, Kazuhide Katayama, Hiroyuki Kusuhara and Yoshitane Nozaki
      Drug Metabolism and Disposition November 2020, 48 (11) 1183-1190; DOI: https://doi.org/10.1124/dmd.120.000099

  4. Khojasteh, S. Cyrus

    1. Open Access
      Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti–Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
      Hao Cai, Victor Yip, M. Violet Lee, Sylvia Wong, Ola Saad, Shuguang Ma, Nina Ljumanovic, S. Cyrus Khojasteh, Amrita V. Kamath and Ben-Quan Shen
      Drug Metabolism and Disposition November 2020, 48 (11) 1161-1168; DOI: https://doi.org/10.1124/dmd.120.000092

  5. King, Lloyd

    1. Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Mari Davies, Prabha Peramuhendige, Lloyd King, Melanie Golding, Apoorva Kotian, Mark Penney, Syeda Shah and Nenad Manevski
      Drug Metabolism and Disposition November 2020, 48 (11) 1169-1182; DOI: https://doi.org/10.1124/dmd.120.000111

  6. Knemeyer, Ian

    1. A Two-Tiered In Vitro Approach to De-Risk Drug Candidates for Potential Bile Salt Export Pump Inhibition Liabilities in Drug Discovery
      Michael J. Hafey, Robert Houle, Keith Q. Tanis, Ian Knemeyer, Jackie Shang, Qing Chen, Andreas Baudy, James Monroe, Frank D. Sistare and Raymond Evers
      Drug Metabolism and Disposition November 2020, 48 (11) 1147-1160; DOI: https://doi.org/10.1124/dmd.120.000086

  7. Kotian, Apoorva

    1. Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Mari Davies, Prabha Peramuhendige, Lloyd King, Melanie Golding, Apoorva Kotian, Mark Penney, Syeda Shah and Nenad Manevski
      Drug Metabolism and Disposition November 2020, 48 (11) 1169-1182; DOI: https://doi.org/10.1124/dmd.120.000111

  8. Kumar, Vineet

    1. Successful Prediction of Positron Emission Tomography–Imaged Metformin Hepatic Uptake Clearance in Humans Using the Quantitative Proteomics–Informed Relative Expression Factor Approach
      Madhav Sachar, Vineet Kumar, Lars C. Gormsen, Ole Lajord Munk and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2020, 48 (11) 1210-1216; DOI: https://doi.org/10.1124/dmd.120.000156

  9. Kusuhara, Hiroyuki

    1. Impact of P-Glycoprotein–Mediated Active Efflux on Drug Distribution into Lumbar Cerebrospinal Fluid in Nonhuman Primates
      Impact of P-Glycoprotein–Mediated Active Efflux on Drug Distribution into Lumbar Cerebrospinal Fluid in Nonhuman Primates
      Yoko Nagaya, Kazuhide Katayama, Hiroyuki Kusuhara and Yoshitane Nozaki
      Drug Metabolism and Disposition November 2020, 48 (11) 1183-1190; DOI: https://doi.org/10.1124/dmd.120.000099

L

  1. L. Orton, Alexandra

    1. A Laboratory-Specific Scaling Factor to Predict the In Vivo Human Clearance of Aldehyde Oxidase Substrates
      Mailys De Sousa Mendes, Alexandra L. Orton, Helen E. Humphries, Barry Jones, Iain Gardner, Sibylle Neuhoff and Venkatesh Pilla Reddy
      Drug Metabolism and Disposition November 2020, 48 (11) 1231-1238; DOI: https://doi.org/10.1124/dmd.120.000082

  2. Lee, M. Violet

    1. Open Access
      Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti–Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
      Hao Cai, Victor Yip, M. Violet Lee, Sylvia Wong, Ola Saad, Shuguang Ma, Nina Ljumanovic, S. Cyrus Khojasteh, Amrita V. Kamath and Ben-Quan Shen
      Drug Metabolism and Disposition November 2020, 48 (11) 1161-1168; DOI: https://doi.org/10.1124/dmd.120.000092

  3. Leeder, J. Steven

    1. The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites
      Brian D. Chapron, Jean C. Dinh, Paul C. Toren, Andrea Gaedigk and J. Steven Leeder
      Drug Metabolism and Disposition November 2020, 48 (11) 1113-1120; DOI: https://doi.org/10.1124/dmd.120.000188
    2. Functional Consequences of Pravastatin Isomerization on OATP1B1-Mediated Transport
      Jonathan B. Wagner, Melissa Ruggiero, J. Steven Leeder and Bruno Hagenbuch
      Drug Metabolism and Disposition November 2020, 48 (11) 1192-1198; DOI: https://doi.org/10.1124/dmd.120.000122

  4. Liu, Mingyao

    1. Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Jian Lu, Ang Chen, Xinrun Ma, Xuyang Shang, Yuanjin Zhang, Yuanqing Guo, Mingyao Liu and Xin Wang
      Drug Metabolism and Disposition November 2020, 48 (11) 1129-1136; DOI: https://doi.org/10.1124/dmd.120.000114

  5. Ljumanovic, Nina

    1. Open Access
      Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti–Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
      Hao Cai, Victor Yip, M. Violet Lee, Sylvia Wong, Ola Saad, Shuguang Ma, Nina Ljumanovic, S. Cyrus Khojasteh, Amrita V. Kamath and Ben-Quan Shen
      Drug Metabolism and Disposition November 2020, 48 (11) 1161-1168; DOI: https://doi.org/10.1124/dmd.120.000092

  6. Lu, Jian

    1. Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Jian Lu, Ang Chen, Xinrun Ma, Xuyang Shang, Yuanjin Zhang, Yuanqing Guo, Mingyao Liu and Xin Wang
      Drug Metabolism and Disposition November 2020, 48 (11) 1129-1136; DOI: https://doi.org/10.1124/dmd.120.000114

M

  1. Ma, Shuguang

    1. Open Access
      Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti–Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
      Hao Cai, Victor Yip, M. Violet Lee, Sylvia Wong, Ola Saad, Shuguang Ma, Nina Ljumanovic, S. Cyrus Khojasteh, Amrita V. Kamath and Ben-Quan Shen
      Drug Metabolism and Disposition November 2020, 48 (11) 1161-1168; DOI: https://doi.org/10.1124/dmd.120.000092

  2. Ma, Xinrun

    1. Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Jian Lu, Ang Chen, Xinrun Ma, Xuyang Shang, Yuanjin Zhang, Yuanqing Guo, Mingyao Liu and Xin Wang
      Drug Metabolism and Disposition November 2020, 48 (11) 1129-1136; DOI: https://doi.org/10.1124/dmd.120.000114

  3. Manevski, Nenad

    1. Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Mari Davies, Prabha Peramuhendige, Lloyd King, Melanie Golding, Apoorva Kotian, Mark Penney, Syeda Shah and Nenad Manevski
      Drug Metabolism and Disposition November 2020, 48 (11) 1169-1182; DOI: https://doi.org/10.1124/dmd.120.000111

  4. Mareus, Ricky

    1. Exposure of Rats to Multiple Oral Doses of Dichloroacetate Results in Upregulation of Hepatic Glutathione Transferases and NAD(P)H Dehydrogenase [Quinone] 1
      Edwin J. Squirewell, Ricky Mareus, Lloyd P. Horne, Peter W. Stacpoole and Margaret O. James
      Drug Metabolism and Disposition November 2020, 48 (11) 1224-1230; DOI: https://doi.org/10.1124/dmd.120.000143

  5. McGinnity, Dermot F.

    1. Evaluation of the Disconnect between Hepatocyte and Microsome Intrinsic Clearance and In Vitro In Vivo Extrapolation Performance
      Beth Williamson, Stephanie Harlfinger and Dermot F. McGinnity
      Drug Metabolism and Disposition November 2020, 48 (11) 1137-1146; DOI: https://doi.org/10.1124/dmd.120.000131

  6. Monroe, James

    1. A Two-Tiered In Vitro Approach to De-Risk Drug Candidates for Potential Bile Salt Export Pump Inhibition Liabilities in Drug Discovery
      Michael J. Hafey, Robert Houle, Keith Q. Tanis, Ian Knemeyer, Jackie Shang, Qing Chen, Andreas Baudy, James Monroe, Frank D. Sistare and Raymond Evers
      Drug Metabolism and Disposition November 2020, 48 (11) 1147-1160; DOI: https://doi.org/10.1124/dmd.120.000086

  7. Munk, Ole Lajord

    1. Successful Prediction of Positron Emission Tomography–Imaged Metformin Hepatic Uptake Clearance in Humans Using the Quantitative Proteomics–Informed Relative Expression Factor Approach
      Madhav Sachar, Vineet Kumar, Lars C. Gormsen, Ole Lajord Munk and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2020, 48 (11) 1210-1216; DOI: https://doi.org/10.1124/dmd.120.000156

N

  1. Nagaya, Yoko

    1. Impact of P-Glycoprotein–Mediated Active Efflux on Drug Distribution into Lumbar Cerebrospinal Fluid in Nonhuman Primates
      Impact of P-Glycoprotein–Mediated Active Efflux on Drug Distribution into Lumbar Cerebrospinal Fluid in Nonhuman Primates
      Yoko Nagaya, Kazuhide Katayama, Hiroyuki Kusuhara and Yoshitane Nozaki
      Drug Metabolism and Disposition November 2020, 48 (11) 1183-1190; DOI: https://doi.org/10.1124/dmd.120.000099

  2. Neuhoff, Sibylle

    1. A Laboratory-Specific Scaling Factor to Predict the In Vivo Human Clearance of Aldehyde Oxidase Substrates
      Mailys De Sousa Mendes, Alexandra L. Orton, Helen E. Humphries, Barry Jones, Iain Gardner, Sibylle Neuhoff and Venkatesh Pilla Reddy
      Drug Metabolism and Disposition November 2020, 48 (11) 1231-1238; DOI: https://doi.org/10.1124/dmd.120.000082

  3. Nicolaï, Johan

    1. (–)-<em>N</em>-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-<em>N</em>-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      (–)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
      Drug Metabolism and Disposition November 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089

  4. Nozaki, Yoshitane

    1. Impact of P-Glycoprotein–Mediated Active Efflux on Drug Distribution into Lumbar Cerebrospinal Fluid in Nonhuman Primates
      Impact of P-Glycoprotein–Mediated Active Efflux on Drug Distribution into Lumbar Cerebrospinal Fluid in Nonhuman Primates
      Yoko Nagaya, Kazuhide Katayama, Hiroyuki Kusuhara and Yoshitane Nozaki
      Drug Metabolism and Disposition November 2020, 48 (11) 1183-1190; DOI: https://doi.org/10.1124/dmd.120.000099

P

  1. Penney, Mark

    1. Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Mari Davies, Prabha Peramuhendige, Lloyd King, Melanie Golding, Apoorva Kotian, Mark Penney, Syeda Shah and Nenad Manevski
      Drug Metabolism and Disposition November 2020, 48 (11) 1169-1182; DOI: https://doi.org/10.1124/dmd.120.000111

  2. Peramuhendige, Prabha

    1. Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Mari Davies, Prabha Peramuhendige, Lloyd King, Melanie Golding, Apoorva Kotian, Mark Penney, Syeda Shah and Nenad Manevski
      Drug Metabolism and Disposition November 2020, 48 (11) 1169-1182; DOI: https://doi.org/10.1124/dmd.120.000111

  3. Pilla Reddy, Venkatesh

    1. A Laboratory-Specific Scaling Factor to Predict the In Vivo Human Clearance of Aldehyde Oxidase Substrates
      Mailys De Sousa Mendes, Alexandra L. Orton, Helen E. Humphries, Barry Jones, Iain Gardner, Sibylle Neuhoff and Venkatesh Pilla Reddy
      Drug Metabolism and Disposition November 2020, 48 (11) 1231-1238; DOI: https://doi.org/10.1124/dmd.120.000082

R

  1. Rowland-Faux, Laura

    1. Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats
      Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats
      Edwin J. Squirewell, Marci G. Smeltz, Laura Rowland-Faux, Lloyd P. Horne, Peter W. Stacpoole and Margaret O. James
      Drug Metabolism and Disposition November 2020, 48 (11) 1217-1223; DOI: https://doi.org/10.1124/dmd.120.000142

  2. Ruggiero, Melissa

    1. Functional Consequences of Pravastatin Isomerization on OATP1B1-Mediated Transport
      Jonathan B. Wagner, Melissa Ruggiero, J. Steven Leeder and Bruno Hagenbuch
      Drug Metabolism and Disposition November 2020, 48 (11) 1192-1198; DOI: https://doi.org/10.1124/dmd.120.000122

S

  1. Saad, Ola

    1. Open Access
      Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti–Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
      Hao Cai, Victor Yip, M. Violet Lee, Sylvia Wong, Ola Saad, Shuguang Ma, Nina Ljumanovic, S. Cyrus Khojasteh, Amrita V. Kamath and Ben-Quan Shen
      Drug Metabolism and Disposition November 2020, 48 (11) 1161-1168; DOI: https://doi.org/10.1124/dmd.120.000092

  2. Sachar, Madhav

    1. Successful Prediction of Positron Emission Tomography–Imaged Metformin Hepatic Uptake Clearance in Humans Using the Quantitative Proteomics–Informed Relative Expression Factor Approach
      Madhav Sachar, Vineet Kumar, Lars C. Gormsen, Ole Lajord Munk and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2020, 48 (11) 1210-1216; DOI: https://doi.org/10.1124/dmd.120.000156

  3. Santos, Rex

    1. Characterization of Seasonal Pharmacokinetic Variability in Woodchucks
      Jim Zheng, Scott Balsitis, Rex Santos, Bill J. Smith and Raju Subramanian
      Drug Metabolism and Disposition November 2020, 48 (11) 1199-1209; DOI: https://doi.org/10.1124/dmd.120.000140

  4. Saunders, Kenneth

    1. (–)-<em>N</em>-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-<em>N</em>-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      (–)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
      Drug Metabolism and Disposition November 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089

  5. Scott, Dr. Emily E.

    1. Announcement
      Dr. Emily E. Scott
      Drug Metabolism and Disposition November 2020, 48 (11) 1191; DOI: https://doi.org/10.1124/dmd.120.000249

  6. Shadid, Mohammad

    1. Pharmacokinetics and Catabolism of [3H]TAK-164, a Guanylyl Cyclase C Targeted Antibody-Drug Conjugate
      Jayaprakasam Bolleddula, Abhi Shah, Mohammad Shadid, Afrand Kamali, Michael D. Smith and Swapan K. Chowdhury
      Drug Metabolism and Disposition November 2020, 48 (11) 1239-1245; DOI: https://doi.org/10.1124/dmd.120.000194

  7. Shah, Abhi

    1. Pharmacokinetics and Catabolism of [3H]TAK-164, a Guanylyl Cyclase C Targeted Antibody-Drug Conjugate
      Jayaprakasam Bolleddula, Abhi Shah, Mohammad Shadid, Afrand Kamali, Michael D. Smith and Swapan K. Chowdhury
      Drug Metabolism and Disposition November 2020, 48 (11) 1239-1245; DOI: https://doi.org/10.1124/dmd.120.000194

  8. Shah, Syeda

    1. Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Evaluation of In Vitro Models for Assessment of Human Intestinal Metabolism in Drug Discovery
      Mari Davies, Prabha Peramuhendige, Lloyd King, Melanie Golding, Apoorva Kotian, Mark Penney, Syeda Shah and Nenad Manevski
      Drug Metabolism and Disposition November 2020, 48 (11) 1169-1182; DOI: https://doi.org/10.1124/dmd.120.000111

  9. Shang, Jackie

    1. A Two-Tiered In Vitro Approach to De-Risk Drug Candidates for Potential Bile Salt Export Pump Inhibition Liabilities in Drug Discovery
      Michael J. Hafey, Robert Houle, Keith Q. Tanis, Ian Knemeyer, Jackie Shang, Qing Chen, Andreas Baudy, James Monroe, Frank D. Sistare and Raymond Evers
      Drug Metabolism and Disposition November 2020, 48 (11) 1147-1160; DOI: https://doi.org/10.1124/dmd.120.000086

  10. Shang, Xuyang

    1. Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Jian Lu, Ang Chen, Xinrun Ma, Xuyang Shang, Yuanjin Zhang, Yuanqing Guo, Mingyao Liu and Xin Wang
      Drug Metabolism and Disposition November 2020, 48 (11) 1129-1136; DOI: https://doi.org/10.1124/dmd.120.000114

  11. Shen, Ben-Quan

    1. Open Access
      Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti–Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
      Hao Cai, Victor Yip, M. Violet Lee, Sylvia Wong, Ola Saad, Shuguang Ma, Nina Ljumanovic, S. Cyrus Khojasteh, Amrita V. Kamath and Ben-Quan Shen
      Drug Metabolism and Disposition November 2020, 48 (11) 1161-1168; DOI: https://doi.org/10.1124/dmd.120.000092

  12. Sistare, Frank D.

    1. A Two-Tiered In Vitro Approach to De-Risk Drug Candidates for Potential Bile Salt Export Pump Inhibition Liabilities in Drug Discovery
      Michael J. Hafey, Robert Houle, Keith Q. Tanis, Ian Knemeyer, Jackie Shang, Qing Chen, Andreas Baudy, James Monroe, Frank D. Sistare and Raymond Evers
      Drug Metabolism and Disposition November 2020, 48 (11) 1147-1160; DOI: https://doi.org/10.1124/dmd.120.000086

  13. Smeltz, Marci G.

    1. Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats
      Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats
      Edwin J. Squirewell, Marci G. Smeltz, Laura Rowland-Faux, Lloyd P. Horne, Peter W. Stacpoole and Margaret O. James
      Drug Metabolism and Disposition November 2020, 48 (11) 1217-1223; DOI: https://doi.org/10.1124/dmd.120.000142

  14. Smith, Bill J.

    1. Characterization of Seasonal Pharmacokinetic Variability in Woodchucks
      Jim Zheng, Scott Balsitis, Rex Santos, Bill J. Smith and Raju Subramanian
      Drug Metabolism and Disposition November 2020, 48 (11) 1199-1209; DOI: https://doi.org/10.1124/dmd.120.000140

  15. Smith, Michael D.

    1. Pharmacokinetics and Catabolism of [3H]TAK-164, a Guanylyl Cyclase C Targeted Antibody-Drug Conjugate
      Jayaprakasam Bolleddula, Abhi Shah, Mohammad Shadid, Afrand Kamali, Michael D. Smith and Swapan K. Chowdhury
      Drug Metabolism and Disposition November 2020, 48 (11) 1239-1245; DOI: https://doi.org/10.1124/dmd.120.000194

  16. Squirewell, Edwin J.

    1. Exposure of Rats to Multiple Oral Doses of Dichloroacetate Results in Upregulation of Hepatic Glutathione Transferases and NAD(P)H Dehydrogenase [Quinone] 1
      Edwin J. Squirewell, Ricky Mareus, Lloyd P. Horne, Peter W. Stacpoole and Margaret O. James
      Drug Metabolism and Disposition November 2020, 48 (11) 1224-1230; DOI: https://doi.org/10.1124/dmd.120.000143
    2. Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats
      Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats
      Edwin J. Squirewell, Marci G. Smeltz, Laura Rowland-Faux, Lloyd P. Horne, Peter W. Stacpoole and Margaret O. James
      Drug Metabolism and Disposition November 2020, 48 (11) 1217-1223; DOI: https://doi.org/10.1124/dmd.120.000142

  17. Stacpoole, Peter W.

    1. Exposure of Rats to Multiple Oral Doses of Dichloroacetate Results in Upregulation of Hepatic Glutathione Transferases and NAD(P)H Dehydrogenase [Quinone] 1
      Edwin J. Squirewell, Ricky Mareus, Lloyd P. Horne, Peter W. Stacpoole and Margaret O. James
      Drug Metabolism and Disposition November 2020, 48 (11) 1224-1230; DOI: https://doi.org/10.1124/dmd.120.000143
    2. Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats
      Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats
      Edwin J. Squirewell, Marci G. Smeltz, Laura Rowland-Faux, Lloyd P. Horne, Peter W. Stacpoole and Margaret O. James
      Drug Metabolism and Disposition November 2020, 48 (11) 1217-1223; DOI: https://doi.org/10.1124/dmd.120.000142

  18. Subramanian, Raju

    1. Characterization of Seasonal Pharmacokinetic Variability in Woodchucks
      Jim Zheng, Scott Balsitis, Rex Santos, Bill J. Smith and Raju Subramanian
      Drug Metabolism and Disposition November 2020, 48 (11) 1199-1209; DOI: https://doi.org/10.1124/dmd.120.000140

T

  1. Tanis, Keith Q.

    1. A Two-Tiered In Vitro Approach to De-Risk Drug Candidates for Potential Bile Salt Export Pump Inhibition Liabilities in Drug Discovery
      Michael J. Hafey, Robert Houle, Keith Q. Tanis, Ian Knemeyer, Jackie Shang, Qing Chen, Andreas Baudy, James Monroe, Frank D. Sistare and Raymond Evers
      Drug Metabolism and Disposition November 2020, 48 (11) 1147-1160; DOI: https://doi.org/10.1124/dmd.120.000086

  2. Toren, Paul C.

    1. The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites
      Brian D. Chapron, Jean C. Dinh, Paul C. Toren, Andrea Gaedigk and J. Steven Leeder
      Drug Metabolism and Disposition November 2020, 48 (11) 1113-1120; DOI: https://doi.org/10.1124/dmd.120.000188

U

  1. Unadkat, Jashvant D.

    1. Successful Prediction of Positron Emission Tomography–Imaged Metformin Hepatic Uptake Clearance in Humans Using the Quantitative Proteomics–Informed Relative Expression Factor Approach
      Madhav Sachar, Vineet Kumar, Lars C. Gormsen, Ole Lajord Munk and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2020, 48 (11) 1210-1216; DOI: https://doi.org/10.1124/dmd.120.000156

  2. Ungell, Anna-Lena

    1. (–)-<em>N</em>-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-<em>N</em>-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      (–)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
      Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
      Drug Metabolism and Disposition November 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089

W

  1. Wagner, Jonathan B.

    1. Functional Consequences of Pravastatin Isomerization on OATP1B1-Mediated Transport
      Jonathan B. Wagner, Melissa Ruggiero, J. Steven Leeder and Bruno Hagenbuch
      Drug Metabolism and Disposition November 2020, 48 (11) 1192-1198; DOI: https://doi.org/10.1124/dmd.120.000122

  2. Wang, Xin

    1. Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Jian Lu, Ang Chen, Xinrun Ma, Xuyang Shang, Yuanjin Zhang, Yuanqing Guo, Mingyao Liu and Xin Wang
      Drug Metabolism and Disposition November 2020, 48 (11) 1129-1136; DOI: https://doi.org/10.1124/dmd.120.000114

  3. Williamson, Beth

    1. Evaluation of the Disconnect between Hepatocyte and Microsome Intrinsic Clearance and In Vitro In Vivo Extrapolation Performance
      Beth Williamson, Stephanie Harlfinger and Dermot F. McGinnity
      Drug Metabolism and Disposition November 2020, 48 (11) 1137-1146; DOI: https://doi.org/10.1124/dmd.120.000131

  4. Wong, Sylvia

    1. Open Access
      Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti–Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
      Hao Cai, Victor Yip, M. Violet Lee, Sylvia Wong, Ola Saad, Shuguang Ma, Nina Ljumanovic, S. Cyrus Khojasteh, Amrita V. Kamath and Ben-Quan Shen
      Drug Metabolism and Disposition November 2020, 48 (11) 1161-1168; DOI: https://doi.org/10.1124/dmd.120.000092

Y

  1. Yip, Victor

    1. Open Access
      Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti–Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
      Hao Cai, Victor Yip, M. Violet Lee, Sylvia Wong, Ola Saad, Shuguang Ma, Nina Ljumanovic, S. Cyrus Khojasteh, Amrita V. Kamath and Ben-Quan Shen
      Drug Metabolism and Disposition November 2020, 48 (11) 1161-1168; DOI: https://doi.org/10.1124/dmd.120.000092

Z

  1. Zhang, Yuanjin

    1. Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model
      Jian Lu, Ang Chen, Xinrun Ma, Xuyang Shang, Yuanjin Zhang, Yuanqing Guo, Mingyao Liu and Xin Wang
      Drug Metabolism and Disposition November 2020, 48 (11) 1129-1136; DOI: https://doi.org/10.1124/dmd.120.000114

  2. Zheng, Jim

    1. Characterization of Seasonal Pharmacokinetic Variability in Woodchucks
      Jim Zheng, Scott Balsitis, Rex Santos, Bill J. Smith and Raju Subramanian
      Drug Metabolism and Disposition November 2020, 48 (11) 1199-1209; DOI: https://doi.org/10.1124/dmd.120.000140
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