Research ArticleArticle
(–)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
Drug Metabolism and Disposition November 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089
Marie-Lynn Cuypers
Pharmaceutical Sciences, KU Leuven, Leuven, Belgium (M.-L.C., C.B.) and Development Science, UCB Biopharma SRL, Braine-l’Alleud, Belgium (H.C., E.G., P.B., K.S., C.D., S.D., A.-L.U., J.N.)
Hugues Chanteux
Pharmaceutical Sciences, KU Leuven, Leuven, Belgium (M.-L.C., C.B.) and Development Science, UCB Biopharma SRL, Braine-l’Alleud, Belgium (H.C., E.G., P.B., K.S., C.D., S.D., A.-L.U., J.N.)
Eric Gillent
Pharmaceutical Sciences, KU Leuven, Leuven, Belgium (M.-L.C., C.B.) and Development Science, UCB Biopharma SRL, Braine-l’Alleud, Belgium (H.C., E.G., P.B., K.S., C.D., S.D., A.-L.U., J.N.)
Pierre Bonnaillie
Pharmaceutical Sciences, KU Leuven, Leuven, Belgium (M.-L.C., C.B.) and Development Science, UCB Biopharma SRL, Braine-l’Alleud, Belgium (H.C., E.G., P.B., K.S., C.D., S.D., A.-L.U., J.N.)
Kenneth Saunders
Pharmaceutical Sciences, KU Leuven, Leuven, Belgium (M.-L.C., C.B.) and Development Science, UCB Biopharma SRL, Braine-l’Alleud, Belgium (H.C., E.G., P.B., K.S., C.D., S.D., A.-L.U., J.N.)
Claire Beckers
Pharmaceutical Sciences, KU Leuven, Leuven, Belgium (M.-L.C., C.B.) and Development Science, UCB Biopharma SRL, Braine-l’Alleud, Belgium (H.C., E.G., P.B., K.S., C.D., S.D., A.-L.U., J.N.)
Claude Delatour
Pharmaceutical Sciences, KU Leuven, Leuven, Belgium (M.-L.C., C.B.) and Development Science, UCB Biopharma SRL, Braine-l’Alleud, Belgium (H.C., E.G., P.B., K.S., C.D., S.D., A.-L.U., J.N.)
Sylvie Dell’Aiera
Pharmaceutical Sciences, KU Leuven, Leuven, Belgium (M.-L.C., C.B.) and Development Science, UCB Biopharma SRL, Braine-l’Alleud, Belgium (H.C., E.G., P.B., K.S., C.D., S.D., A.-L.U., J.N.)
Anna-Lena Ungell
Pharmaceutical Sciences, KU Leuven, Leuven, Belgium (M.-L.C., C.B.) and Development Science, UCB Biopharma SRL, Braine-l’Alleud, Belgium (H.C., E.G., P.B., K.S., C.D., S.D., A.-L.U., J.N.)
Johan Nicolaï
Pharmaceutical Sciences, KU Leuven, Leuven, Belgium (M.-L.C., C.B.) and Development Science, UCB Biopharma SRL, Braine-l’Alleud, Belgium (H.C., E.G., P.B., K.S., C.D., S.D., A.-L.U., J.N.)
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In this issue
Research ArticleArticle
CYP2C19 Inhibition by (–)-N-3-Benzylphenobarbital in suspended human hepatocytes
Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
Drug Metabolism and Disposition November 1, 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089
Research ArticleArticle
CYP2C19 Inhibition by (–)-N-3-Benzylphenobarbital in suspended human hepatocytes
Marie-Lynn Cuypers, Hugues Chanteux, Eric Gillent, Pierre Bonnaillie, Kenneth Saunders, Claire Beckers, Claude Delatour, Sylvie Dell’Aiera, Anna-Lena Ungell and Johan Nicolaï
Drug Metabolism and Disposition November 1, 2020, 48 (11) 1121-1128; DOI: https://doi.org/10.1124/dmd.120.000089
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