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Research ArticleArticle

In Vitro Hepatic Uptake in Human and Monkey Hepatocytes in the Presence and Absence of Serum Protein and Its In Vitro to In Vivo Extrapolation

Xiaomin Liang, Yeojin Park, Natalie DeForest, Jia Hao, Xiaofeng Zhao, Congrong Niu, Kelly Wang, Bill Smith and Yurong Lai
Drug Metabolism and Disposition December 2020, 48 (12) 1283-1292; DOI: https://doi.org/10.1124/dmd.120.000163

Article Information

vol. 48 no. 12 1283-1292
DOI 
https://doi.org/10.1124/dmd.120.000163
PubMed 
33037043
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 27, 2020
  • Accepted September 28, 2020
  • Published online November 18, 2020.

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Copyright & Usage 
Copyright © 2020 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Xiaomin Liang⇑,
  2. Yeojin Park,
  3. Natalie DeForest,
  4. Jia Hao,
  5. Xiaofeng Zhao,
  6. Congrong Niu,
  7. Kelly Wang,
  8. Bill Smith, and
  9. Yurong Lai⇑
  1. Drug Metabolism, Gilead Sciences Inc., Foster City, California
  1. Address correspondence to:
    Dr. Yurong Lai, Drug Metabolism, Gilead Sciences Inc., 333 Lakeside Dr., Foster City, CA 94404. E-mail: yurong.lai{at}gilead.com; or
  2. Dr. Xiaomin Liang, Drug Metabolism, Gilead Sciences Inc., 333 Lakeside Dr., Foster City, CA 94404. E-mail: Xiaomin.Liang{at}gilead.com
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Research ArticleArticle

Hepatic Uptake in Human and Monkey Hepatocytes and Its IVIVE

Xiaomin Liang, Yeojin Park, Natalie DeForest, Jia Hao, Xiaofeng Zhao, Congrong Niu, Kelly Wang, Bill Smith and Yurong Lai
Drug Metabolism and Disposition December 1, 2020, 48 (12) 1283-1292; DOI: https://doi.org/10.1124/dmd.120.000163
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