A Multicompartment Human Kidney Proximal Tubule-on-a-Chip Replicates Cell Polarization–Dependent Cisplatin Toxicity

Tom T.G. Nieskens; Mikael Persson; Edward J. Kelly; Anna-Karin Sjögren

doi:10.1124/dmd.120.000098

Research ArticleArticle

A Multicompartment Human Kidney Proximal Tubule-on-a-Chip Replicates Cell Polarization–Dependent Cisplatin Toxicity

Tom T.G. Nieskens, Mikael Persson, Edward J. Kelly and Anna-Karin Sjögren

Drug Metabolism and Disposition December 2020, 48 (12) 1303-1311; DOI: https://doi.org/10.1124/dmd.120.000098

Tom T.G. Nieskens

CVRM Safety, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Gothenburg, Sweden (T.T.G.N., M.P., A.-K.S.) and Department of Pharmaceutics and Kidney Research Institute, University of Washington, Seattle, Washington (E.J.K.)

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Mikael Persson

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Edward J. Kelly

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Anna-Karin Sjögren

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Drug Metabolism and Disposition

Vol. 48, Issue 12

1 Dec 2020

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