Research ArticleArticle
In Vitro Characterization of Ertugliflozin Metabolism by UDP-Glucuronosyltransferase and Cytochrome P450 Enzymes
Kimberly Lapham, Ernesto Callegari, Julie Cianfrogna, Jian Lin, Mark Niosi, Christine C. Orozco, Raman Sharma and Theunis C. Goosen
Drug Metabolism and Disposition December 2020, 48 (12) 1350-1363; DOI: https://doi.org/10.1124/dmd.120.000171
Kimberly Lapham
Medicine Design, Pfizer Inc., Groton, Connecticut (K.L., E.C., J.L., M.N., C.C.O., R.S., T.C.G.) and Pfizer Inc., La Jolla, California (J.C.)
Ernesto Callegari
Medicine Design, Pfizer Inc., Groton, Connecticut (K.L., E.C., J.L., M.N., C.C.O., R.S., T.C.G.) and Pfizer Inc., La Jolla, California (J.C.)
Julie Cianfrogna
Medicine Design, Pfizer Inc., Groton, Connecticut (K.L., E.C., J.L., M.N., C.C.O., R.S., T.C.G.) and Pfizer Inc., La Jolla, California (J.C.)
Jian Lin
Medicine Design, Pfizer Inc., Groton, Connecticut (K.L., E.C., J.L., M.N., C.C.O., R.S., T.C.G.) and Pfizer Inc., La Jolla, California (J.C.)
Mark Niosi
Medicine Design, Pfizer Inc., Groton, Connecticut (K.L., E.C., J.L., M.N., C.C.O., R.S., T.C.G.) and Pfizer Inc., La Jolla, California (J.C.)
Christine C. Orozco
Medicine Design, Pfizer Inc., Groton, Connecticut (K.L., E.C., J.L., M.N., C.C.O., R.S., T.C.G.) and Pfizer Inc., La Jolla, California (J.C.)
Raman Sharma
Medicine Design, Pfizer Inc., Groton, Connecticut (K.L., E.C., J.L., M.N., C.C.O., R.S., T.C.G.) and Pfizer Inc., La Jolla, California (J.C.)
Theunis C. Goosen
Medicine Design, Pfizer Inc., Groton, Connecticut (K.L., E.C., J.L., M.N., C.C.O., R.S., T.C.G.) and Pfizer Inc., La Jolla, California (J.C.)
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Research ArticleArticle
Ertugliflozin Phenotyping
Kimberly Lapham, Ernesto Callegari, Julie Cianfrogna, Jian Lin, Mark Niosi, Christine C. Orozco, Raman Sharma and Theunis C. Goosen
Drug Metabolism and Disposition December 1, 2020, 48 (12) 1350-1363; DOI: https://doi.org/10.1124/dmd.120.000171
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