Piperine Is a Mechanism-Based Inactivator of CYP3A

Tiantian Cui; Qian Wang; Xiaoxiao Tian; Kehan Zhang; Ying Peng; Jiang Zheng

doi:10.1124/dmd.119.088955

Research ArticleArticle

Piperine Is a Mechanism-Based Inactivator of CYP3A

Tiantian Cui, Qian Wang, Xiaoxiao Tian, Kehan Zhang, Ying Peng and Jiang Zheng

Drug Metabolism and Disposition February 2020, 48 (2) 123-134; DOI: https://doi.org/10.1124/dmd.119.088955

Tiantian Cui

State Key Laboratory of Functions and Applications of Medicinal Plants, Key Laboratory of Pharmaceutics of Guizhou Province, and Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, P. R. China

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Qian Wang

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Xiaoxiao Tian

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Kehan Zhang

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Ying Peng

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For correspondence: yingpeng1999@163.com

Jiang Zheng

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For correspondence: zhengneu@yahoo.com

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Drug Metabolism and Disposition

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1 Feb 2020

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