Advertisement

Index by author

March 01, 2020; Volume 48,Issue 3

A

  1. Asenjo, Anna B.

    1. The Human UGT2B7 Nanodisc
      Ian Cook, Anna B. Asenjo, Hernando Sosa and Thomas S. Leyh
      Drug Metabolism and Disposition March 2020, 48 (3) 198-204; DOI: https://doi.org/10.1124/dmd.119.089946

B

  1. Badée, Justine

    1. Use of Phenotypically Poor Metabolizer Individual Donor Human Liver Microsomes To Identify Selective Substrates of UGT2B10
      Nicolo Milani, NaHong Qiu, Birgit Molitor, Justine Badée, Gabriele Cruciani and Stephen Fowler
      Drug Metabolism and Disposition March 2020, 48 (3) 176-186; DOI: https://doi.org/10.1124/dmd.119.089482

  2. Balani, Suresh K.

    1. Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
      Sandeepraj Pusalkar, Xiaofei Zhou, Yuexian Li, Lawrence Cohen, Jun Johnny Yang, Suresh K. Balani, Cindy Xia, Wen Chyi Shyu, Chuang Lu, Karthik Venkatakrishnan and Swapan K. Chowdhury
      Drug Metabolism and Disposition March 2020, 48 (3) 217-229; DOI: https://doi.org/10.1124/dmd.119.087338

  3. Bjånes, Tormod K.

    1. Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Open Access
      Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Tormod K. Bjånes, Lars Petter Jordheim, Jan Schjøtt, Tina Kamceva, Emeline Cros-Perrial, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis, Emmet McCormack and Bettina Riedel
      Drug Metabolism and Disposition March 2020, 48 (3) 153-158; DOI: https://doi.org/10.1124/dmd.119.089334

  4. Boone, Ryan M.

    1. Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified
      Daniel H. Breysse, Ryan M. Boone, Cameron M. Long, Miranda E. Merrill, Christopher M. Schaupp, Collin C. White, Terrance J. Kavanagh, Edward E. Schmidt and Gary F. Merrill
      Drug Metabolism and Disposition March 2020, 48 (3) 187-197; DOI: https://doi.org/10.1124/dmd.119.089326

  5. Breysse, Daniel H.

    1. Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified
      Daniel H. Breysse, Ryan M. Boone, Cameron M. Long, Miranda E. Merrill, Christopher M. Schaupp, Collin C. White, Terrance J. Kavanagh, Edward E. Schmidt and Gary F. Merrill
      Drug Metabolism and Disposition March 2020, 48 (3) 187-197; DOI: https://doi.org/10.1124/dmd.119.089326

C

  1. Chen, Gang

    1. Open Access
      UDP-Glycosyltransferase 3A Metabolism of Polycyclic Aromatic Hydrocarbons: Potential Importance in Aerodigestive Tract Tissues
      Ana G. Vergara, Christy J.W. Watson, Gang Chen and Philip Lazarus
      Drug Metabolism and Disposition March 2020, 48 (3) 160-168; DOI: https://doi.org/10.1124/dmd.119.089284

  2. Chowdhury, Swapan K.

    1. Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
      Sandeepraj Pusalkar, Xiaofei Zhou, Yuexian Li, Lawrence Cohen, Jun Johnny Yang, Suresh K. Balani, Cindy Xia, Wen Chyi Shyu, Chuang Lu, Karthik Venkatakrishnan and Swapan K. Chowdhury
      Drug Metabolism and Disposition March 2020, 48 (3) 217-229; DOI: https://doi.org/10.1124/dmd.119.087338

  3. Cohen, Lawrence

    1. Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
      Sandeepraj Pusalkar, Xiaofei Zhou, Yuexian Li, Lawrence Cohen, Jun Johnny Yang, Suresh K. Balani, Cindy Xia, Wen Chyi Shyu, Chuang Lu, Karthik Venkatakrishnan and Swapan K. Chowdhury
      Drug Metabolism and Disposition March 2020, 48 (3) 217-229; DOI: https://doi.org/10.1124/dmd.119.087338

  4. Collins, Kimberly S.

    1. Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers
      Kimberly S. Collins, Ingrid F. Metzger, Brandon T. Gufford, Jessica B. Lu, Elizabeth B. Medeiros, Victoria M. Pratt, Todd C. Skaar and Zeruesenay Desta
      Drug Metabolism and Disposition March 2020, 48 (3) 169-175; DOI: https://doi.org/10.1124/dmd.119.089052

  5. Cook, Ian

    1. The Human UGT2B7 Nanodisc
      Ian Cook, Anna B. Asenjo, Hernando Sosa and Thomas S. Leyh
      Drug Metabolism and Disposition March 2020, 48 (3) 198-204; DOI: https://doi.org/10.1124/dmd.119.089946

  6. Cros-Perrial, Emeline

    1. Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Open Access
      Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Tormod K. Bjånes, Lars Petter Jordheim, Jan Schjøtt, Tina Kamceva, Emeline Cros-Perrial, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis, Emmet McCormack and Bettina Riedel
      Drug Metabolism and Disposition March 2020, 48 (3) 153-158; DOI: https://doi.org/10.1124/dmd.119.089334

  7. Cruciani, Gabriele

    1. Use of Phenotypically Poor Metabolizer Individual Donor Human Liver Microsomes To Identify Selective Substrates of UGT2B10
      Nicolo Milani, NaHong Qiu, Birgit Molitor, Justine Badée, Gabriele Cruciani and Stephen Fowler
      Drug Metabolism and Disposition March 2020, 48 (3) 176-186; DOI: https://doi.org/10.1124/dmd.119.089482

D

  1. Desta, Zeruesenay

    1. Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers
      Kimberly S. Collins, Ingrid F. Metzger, Brandon T. Gufford, Jessica B. Lu, Elizabeth B. Medeiros, Victoria M. Pratt, Todd C. Skaar and Zeruesenay Desta
      Drug Metabolism and Disposition March 2020, 48 (3) 169-175; DOI: https://doi.org/10.1124/dmd.119.089052

F

  1. Fowler, Stephen

    1. Use of Phenotypically Poor Metabolizer Individual Donor Human Liver Microsomes To Identify Selective Substrates of UGT2B10
      Nicolo Milani, NaHong Qiu, Birgit Molitor, Justine Badée, Gabriele Cruciani and Stephen Fowler
      Drug Metabolism and Disposition March 2020, 48 (3) 176-186; DOI: https://doi.org/10.1124/dmd.119.089482

G

  1. Gufford, Brandon T.

    1. Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers
      Kimberly S. Collins, Ingrid F. Metzger, Brandon T. Gufford, Jessica B. Lu, Elizabeth B. Medeiros, Victoria M. Pratt, Todd C. Skaar and Zeruesenay Desta
      Drug Metabolism and Disposition March 2020, 48 (3) 169-175; DOI: https://doi.org/10.1124/dmd.119.089052

H

  1. Her, Lucy

    1. Carboxylesterase 1 and Precision Pharmacotherapy: Pharmacogenetics and Nongenetic Regulators
      Lucy Her and Hao-Jie Zhu
      Drug Metabolism and Disposition March 2020, 48 (3) 230-244; DOI: https://doi.org/10.1124/dmd.119.089680

I

  1. Igawa, Yoshiyuki

    1. Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys
      Kayoko Ohura, Yoshiyuki Igawa, Maori Tanaka, Kana Matsumoto, Akiko Kasahara, Naoya Wada, Kazuishi Kubota, Yasuhiro Uno and Teruko Imai
      Drug Metabolism and Disposition March 2020, 48 (3) 146-152; DOI: https://doi.org/10.1124/dmd.119.089011

  2. Imai, Teruko

    1. Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys
      Kayoko Ohura, Yoshiyuki Igawa, Maori Tanaka, Kana Matsumoto, Akiko Kasahara, Naoya Wada, Kazuishi Kubota, Yasuhiro Uno and Teruko Imai
      Drug Metabolism and Disposition March 2020, 48 (3) 146-152; DOI: https://doi.org/10.1124/dmd.119.089011

J

  1. Jordheim, Lars Petter

    1. Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Open Access
      Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Tormod K. Bjånes, Lars Petter Jordheim, Jan Schjøtt, Tina Kamceva, Emeline Cros-Perrial, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis, Emmet McCormack and Bettina Riedel
      Drug Metabolism and Disposition March 2020, 48 (3) 153-158; DOI: https://doi.org/10.1124/dmd.119.089334

K

  1. Kamceva, Tina

    1. Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Open Access
      Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Tormod K. Bjånes, Lars Petter Jordheim, Jan Schjøtt, Tina Kamceva, Emeline Cros-Perrial, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis, Emmet McCormack and Bettina Riedel
      Drug Metabolism and Disposition March 2020, 48 (3) 153-158; DOI: https://doi.org/10.1124/dmd.119.089334

  2. Kasahara, Akiko

    1. Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys
      Kayoko Ohura, Yoshiyuki Igawa, Maori Tanaka, Kana Matsumoto, Akiko Kasahara, Naoya Wada, Kazuishi Kubota, Yasuhiro Uno and Teruko Imai
      Drug Metabolism and Disposition March 2020, 48 (3) 146-152; DOI: https://doi.org/10.1124/dmd.119.089011

  3. Kavanagh, Terrance J.

    1. Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified
      Daniel H. Breysse, Ryan M. Boone, Cameron M. Long, Miranda E. Merrill, Christopher M. Schaupp, Collin C. White, Terrance J. Kavanagh, Edward E. Schmidt and Gary F. Merrill
      Drug Metabolism and Disposition March 2020, 48 (3) 187-197; DOI: https://doi.org/10.1124/dmd.119.089326

  4. Kotopoulis, Spiros

    1. Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Open Access
      Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Tormod K. Bjånes, Lars Petter Jordheim, Jan Schjøtt, Tina Kamceva, Emeline Cros-Perrial, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis, Emmet McCormack and Bettina Riedel
      Drug Metabolism and Disposition March 2020, 48 (3) 153-158; DOI: https://doi.org/10.1124/dmd.119.089334

  5. Kubota, Kazuishi

    1. Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys
      Kayoko Ohura, Yoshiyuki Igawa, Maori Tanaka, Kana Matsumoto, Akiko Kasahara, Naoya Wada, Kazuishi Kubota, Yasuhiro Uno and Teruko Imai
      Drug Metabolism and Disposition March 2020, 48 (3) 146-152; DOI: https://doi.org/10.1124/dmd.119.089011

L

  1. Lai, Yurong

    1. Induction of Human Intestinal and Hepatic Organic Anion Transporting Polypeptides: Where Is the Evidence for Its Relevance in Drug-Drug Interactions?
      A. David Rodrigues, Yurong Lai, Hong Shen, Manthena V.S. Varma, Andrew Rowland and Stefan Oswald
      Drug Metabolism and Disposition March 2020, 48 (3) 205-216; DOI: https://doi.org/10.1124/dmd.119.089615

  2. Langer, Anika

    1. Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Open Access
      Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Tormod K. Bjånes, Lars Petter Jordheim, Jan Schjøtt, Tina Kamceva, Emeline Cros-Perrial, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis, Emmet McCormack and Bettina Riedel
      Drug Metabolism and Disposition March 2020, 48 (3) 153-158; DOI: https://doi.org/10.1124/dmd.119.089334

  3. Lazarus, Philip

    1. Open Access
      UDP-Glycosyltransferase 3A Metabolism of Polycyclic Aromatic Hydrocarbons: Potential Importance in Aerodigestive Tract Tissues
      Ana G. Vergara, Christy J.W. Watson, Gang Chen and Philip Lazarus
      Drug Metabolism and Disposition March 2020, 48 (3) 160-168; DOI: https://doi.org/10.1124/dmd.119.089284

  4. Leyh, Thomas S.

    1. The Human UGT2B7 Nanodisc
      Ian Cook, Anna B. Asenjo, Hernando Sosa and Thomas S. Leyh
      Drug Metabolism and Disposition March 2020, 48 (3) 198-204; DOI: https://doi.org/10.1124/dmd.119.089946

  5. Li, Yuexian

    1. Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
      Sandeepraj Pusalkar, Xiaofei Zhou, Yuexian Li, Lawrence Cohen, Jun Johnny Yang, Suresh K. Balani, Cindy Xia, Wen Chyi Shyu, Chuang Lu, Karthik Venkatakrishnan and Swapan K. Chowdhury
      Drug Metabolism and Disposition March 2020, 48 (3) 217-229; DOI: https://doi.org/10.1124/dmd.119.087338

  6. Long, Cameron M.

    1. Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified
      Daniel H. Breysse, Ryan M. Boone, Cameron M. Long, Miranda E. Merrill, Christopher M. Schaupp, Collin C. White, Terrance J. Kavanagh, Edward E. Schmidt and Gary F. Merrill
      Drug Metabolism and Disposition March 2020, 48 (3) 187-197; DOI: https://doi.org/10.1124/dmd.119.089326

  7. Lu, Chuang

    1. Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
      Sandeepraj Pusalkar, Xiaofei Zhou, Yuexian Li, Lawrence Cohen, Jun Johnny Yang, Suresh K. Balani, Cindy Xia, Wen Chyi Shyu, Chuang Lu, Karthik Venkatakrishnan and Swapan K. Chowdhury
      Drug Metabolism and Disposition March 2020, 48 (3) 217-229; DOI: https://doi.org/10.1124/dmd.119.087338

  8. Lu, Jessica B.

    1. Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers
      Kimberly S. Collins, Ingrid F. Metzger, Brandon T. Gufford, Jessica B. Lu, Elizabeth B. Medeiros, Victoria M. Pratt, Todd C. Skaar and Zeruesenay Desta
      Drug Metabolism and Disposition March 2020, 48 (3) 169-175; DOI: https://doi.org/10.1124/dmd.119.089052

M

  1. Matsumoto, Kana

    1. Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys
      Kayoko Ohura, Yoshiyuki Igawa, Maori Tanaka, Kana Matsumoto, Akiko Kasahara, Naoya Wada, Kazuishi Kubota, Yasuhiro Uno and Teruko Imai
      Drug Metabolism and Disposition March 2020, 48 (3) 146-152; DOI: https://doi.org/10.1124/dmd.119.089011

  2. McCormack, Emmet

    1. Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Open Access
      Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Tormod K. Bjånes, Lars Petter Jordheim, Jan Schjøtt, Tina Kamceva, Emeline Cros-Perrial, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis, Emmet McCormack and Bettina Riedel
      Drug Metabolism and Disposition March 2020, 48 (3) 153-158; DOI: https://doi.org/10.1124/dmd.119.089334

  3. Medeiros, Elizabeth B.

    1. Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers
      Kimberly S. Collins, Ingrid F. Metzger, Brandon T. Gufford, Jessica B. Lu, Elizabeth B. Medeiros, Victoria M. Pratt, Todd C. Skaar and Zeruesenay Desta
      Drug Metabolism and Disposition March 2020, 48 (3) 169-175; DOI: https://doi.org/10.1124/dmd.119.089052

  4. Merrill, Gary F.

    1. Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified
      Daniel H. Breysse, Ryan M. Boone, Cameron M. Long, Miranda E. Merrill, Christopher M. Schaupp, Collin C. White, Terrance J. Kavanagh, Edward E. Schmidt and Gary F. Merrill
      Drug Metabolism and Disposition March 2020, 48 (3) 187-197; DOI: https://doi.org/10.1124/dmd.119.089326

  5. Merrill, Miranda E.

    1. Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified
      Daniel H. Breysse, Ryan M. Boone, Cameron M. Long, Miranda E. Merrill, Christopher M. Schaupp, Collin C. White, Terrance J. Kavanagh, Edward E. Schmidt and Gary F. Merrill
      Drug Metabolism and Disposition March 2020, 48 (3) 187-197; DOI: https://doi.org/10.1124/dmd.119.089326

  6. Metzger, Ingrid F.

    1. Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers
      Kimberly S. Collins, Ingrid F. Metzger, Brandon T. Gufford, Jessica B. Lu, Elizabeth B. Medeiros, Victoria M. Pratt, Todd C. Skaar and Zeruesenay Desta
      Drug Metabolism and Disposition March 2020, 48 (3) 169-175; DOI: https://doi.org/10.1124/dmd.119.089052

  7. Milani, Nicolo

    1. Use of Phenotypically Poor Metabolizer Individual Donor Human Liver Microsomes To Identify Selective Substrates of UGT2B10
      Nicolo Milani, NaHong Qiu, Birgit Molitor, Justine Badée, Gabriele Cruciani and Stephen Fowler
      Drug Metabolism and Disposition March 2020, 48 (3) 176-186; DOI: https://doi.org/10.1124/dmd.119.089482

  8. Molitor, Birgit

    1. Use of Phenotypically Poor Metabolizer Individual Donor Human Liver Microsomes To Identify Selective Substrates of UGT2B10
      Nicolo Milani, NaHong Qiu, Birgit Molitor, Justine Badée, Gabriele Cruciani and Stephen Fowler
      Drug Metabolism and Disposition March 2020, 48 (3) 176-186; DOI: https://doi.org/10.1124/dmd.119.089482

O

  1. Ohura, Kayoko

    1. Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys
      Kayoko Ohura, Yoshiyuki Igawa, Maori Tanaka, Kana Matsumoto, Akiko Kasahara, Naoya Wada, Kazuishi Kubota, Yasuhiro Uno and Teruko Imai
      Drug Metabolism and Disposition March 2020, 48 (3) 146-152; DOI: https://doi.org/10.1124/dmd.119.089011

  2. Oswald, Stefan

    1. Induction of Human Intestinal and Hepatic Organic Anion Transporting Polypeptides: Where Is the Evidence for Its Relevance in Drug-Drug Interactions?
      A. David Rodrigues, Yurong Lai, Hong Shen, Manthena V.S. Varma, Andrew Rowland and Stefan Oswald
      Drug Metabolism and Disposition March 2020, 48 (3) 205-216; DOI: https://doi.org/10.1124/dmd.119.089615

P

  1. Pratt, Victoria M.

    1. Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers
      Kimberly S. Collins, Ingrid F. Metzger, Brandon T. Gufford, Jessica B. Lu, Elizabeth B. Medeiros, Victoria M. Pratt, Todd C. Skaar and Zeruesenay Desta
      Drug Metabolism and Disposition March 2020, 48 (3) 169-175; DOI: https://doi.org/10.1124/dmd.119.089052

  2. Pusalkar, Sandeepraj

    1. Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
      Sandeepraj Pusalkar, Xiaofei Zhou, Yuexian Li, Lawrence Cohen, Jun Johnny Yang, Suresh K. Balani, Cindy Xia, Wen Chyi Shyu, Chuang Lu, Karthik Venkatakrishnan and Swapan K. Chowdhury
      Drug Metabolism and Disposition March 2020, 48 (3) 217-229; DOI: https://doi.org/10.1124/dmd.119.087338

Q

  1. Qiu, NaHong

    1. Use of Phenotypically Poor Metabolizer Individual Donor Human Liver Microsomes To Identify Selective Substrates of UGT2B10
      Nicolo Milani, NaHong Qiu, Birgit Molitor, Justine Badée, Gabriele Cruciani and Stephen Fowler
      Drug Metabolism and Disposition March 2020, 48 (3) 176-186; DOI: https://doi.org/10.1124/dmd.119.089482

R

  1. Riedel, Bettina

    1. Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Open Access
      Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Tormod K. Bjånes, Lars Petter Jordheim, Jan Schjøtt, Tina Kamceva, Emeline Cros-Perrial, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis, Emmet McCormack and Bettina Riedel
      Drug Metabolism and Disposition March 2020, 48 (3) 153-158; DOI: https://doi.org/10.1124/dmd.119.089334

  2. Rodrigues, A. David

    1. Induction of Human Intestinal and Hepatic Organic Anion Transporting Polypeptides: Where Is the Evidence for Its Relevance in Drug-Drug Interactions?
      A. David Rodrigues, Yurong Lai, Hong Shen, Manthena V.S. Varma, Andrew Rowland and Stefan Oswald
      Drug Metabolism and Disposition March 2020, 48 (3) 205-216; DOI: https://doi.org/10.1124/dmd.119.089615

  3. Rowland, Andrew

    1. Induction of Human Intestinal and Hepatic Organic Anion Transporting Polypeptides: Where Is the Evidence for Its Relevance in Drug-Drug Interactions?
      A. David Rodrigues, Yurong Lai, Hong Shen, Manthena V.S. Varma, Andrew Rowland and Stefan Oswald
      Drug Metabolism and Disposition March 2020, 48 (3) 205-216; DOI: https://doi.org/10.1124/dmd.119.089615

  4. Ruiz de Garibay, Gorka

    1. Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Open Access
      Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Tormod K. Bjånes, Lars Petter Jordheim, Jan Schjøtt, Tina Kamceva, Emeline Cros-Perrial, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis, Emmet McCormack and Bettina Riedel
      Drug Metabolism and Disposition March 2020, 48 (3) 153-158; DOI: https://doi.org/10.1124/dmd.119.089334

S

  1. Schaupp, Christopher M.

    1. Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified
      Daniel H. Breysse, Ryan M. Boone, Cameron M. Long, Miranda E. Merrill, Christopher M. Schaupp, Collin C. White, Terrance J. Kavanagh, Edward E. Schmidt and Gary F. Merrill
      Drug Metabolism and Disposition March 2020, 48 (3) 187-197; DOI: https://doi.org/10.1124/dmd.119.089326

  2. Schjøtt, Jan

    1. Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Open Access
      Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines
      Tormod K. Bjånes, Lars Petter Jordheim, Jan Schjøtt, Tina Kamceva, Emeline Cros-Perrial, Anika Langer, Gorka Ruiz de Garibay, Spiros Kotopoulis, Emmet McCormack and Bettina Riedel
      Drug Metabolism and Disposition March 2020, 48 (3) 153-158; DOI: https://doi.org/10.1124/dmd.119.089334

  3. Schmidt, Edward E.

    1. Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified
      Daniel H. Breysse, Ryan M. Boone, Cameron M. Long, Miranda E. Merrill, Christopher M. Schaupp, Collin C. White, Terrance J. Kavanagh, Edward E. Schmidt and Gary F. Merrill
      Drug Metabolism and Disposition March 2020, 48 (3) 187-197; DOI: https://doi.org/10.1124/dmd.119.089326

  4. Shen, Hong

    1. Induction of Human Intestinal and Hepatic Organic Anion Transporting Polypeptides: Where Is the Evidence for Its Relevance in Drug-Drug Interactions?
      A. David Rodrigues, Yurong Lai, Hong Shen, Manthena V.S. Varma, Andrew Rowland and Stefan Oswald
      Drug Metabolism and Disposition March 2020, 48 (3) 205-216; DOI: https://doi.org/10.1124/dmd.119.089615

  5. Shyu, Wen Chyi

    1. Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
      Sandeepraj Pusalkar, Xiaofei Zhou, Yuexian Li, Lawrence Cohen, Jun Johnny Yang, Suresh K. Balani, Cindy Xia, Wen Chyi Shyu, Chuang Lu, Karthik Venkatakrishnan and Swapan K. Chowdhury
      Drug Metabolism and Disposition March 2020, 48 (3) 217-229; DOI: https://doi.org/10.1124/dmd.119.087338

  6. Skaar, Todd C.

    1. Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers
      Kimberly S. Collins, Ingrid F. Metzger, Brandon T. Gufford, Jessica B. Lu, Elizabeth B. Medeiros, Victoria M. Pratt, Todd C. Skaar and Zeruesenay Desta
      Drug Metabolism and Disposition March 2020, 48 (3) 169-175; DOI: https://doi.org/10.1124/dmd.119.089052

  7. Sosa, Hernando

    1. The Human UGT2B7 Nanodisc
      Ian Cook, Anna B. Asenjo, Hernando Sosa and Thomas S. Leyh
      Drug Metabolism and Disposition March 2020, 48 (3) 198-204; DOI: https://doi.org/10.1124/dmd.119.089946

T

  1. Tanaka, Maori

    1. Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys
      Kayoko Ohura, Yoshiyuki Igawa, Maori Tanaka, Kana Matsumoto, Akiko Kasahara, Naoya Wada, Kazuishi Kubota, Yasuhiro Uno and Teruko Imai
      Drug Metabolism and Disposition March 2020, 48 (3) 146-152; DOI: https://doi.org/10.1124/dmd.119.089011

U

  1. Uno, Yasuhiro

    1. Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys
      Kayoko Ohura, Yoshiyuki Igawa, Maori Tanaka, Kana Matsumoto, Akiko Kasahara, Naoya Wada, Kazuishi Kubota, Yasuhiro Uno and Teruko Imai
      Drug Metabolism and Disposition March 2020, 48 (3) 146-152; DOI: https://doi.org/10.1124/dmd.119.089011

V

  1. Varma, Manthena V.S.

    1. Induction of Human Intestinal and Hepatic Organic Anion Transporting Polypeptides: Where Is the Evidence for Its Relevance in Drug-Drug Interactions?
      A. David Rodrigues, Yurong Lai, Hong Shen, Manthena V.S. Varma, Andrew Rowland and Stefan Oswald
      Drug Metabolism and Disposition March 2020, 48 (3) 205-216; DOI: https://doi.org/10.1124/dmd.119.089615

  2. Venkatakrishnan, Karthik

    1. Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
      Sandeepraj Pusalkar, Xiaofei Zhou, Yuexian Li, Lawrence Cohen, Jun Johnny Yang, Suresh K. Balani, Cindy Xia, Wen Chyi Shyu, Chuang Lu, Karthik Venkatakrishnan and Swapan K. Chowdhury
      Drug Metabolism and Disposition March 2020, 48 (3) 217-229; DOI: https://doi.org/10.1124/dmd.119.087338

  3. Vergara, Ana G.

    1. Open Access
      UDP-Glycosyltransferase 3A Metabolism of Polycyclic Aromatic Hydrocarbons: Potential Importance in Aerodigestive Tract Tissues
      Ana G. Vergara, Christy J.W. Watson, Gang Chen and Philip Lazarus
      Drug Metabolism and Disposition March 2020, 48 (3) 160-168; DOI: https://doi.org/10.1124/dmd.119.089284

W

  1. Wada, Naoya

    1. Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys
      Kayoko Ohura, Yoshiyuki Igawa, Maori Tanaka, Kana Matsumoto, Akiko Kasahara, Naoya Wada, Kazuishi Kubota, Yasuhiro Uno and Teruko Imai
      Drug Metabolism and Disposition March 2020, 48 (3) 146-152; DOI: https://doi.org/10.1124/dmd.119.089011

  2. Watson, Christy J.W.

    1. Open Access
      UDP-Glycosyltransferase 3A Metabolism of Polycyclic Aromatic Hydrocarbons: Potential Importance in Aerodigestive Tract Tissues
      Ana G. Vergara, Christy J.W. Watson, Gang Chen and Philip Lazarus
      Drug Metabolism and Disposition March 2020, 48 (3) 160-168; DOI: https://doi.org/10.1124/dmd.119.089284

  3. White, Collin C.

    1. Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified
      Daniel H. Breysse, Ryan M. Boone, Cameron M. Long, Miranda E. Merrill, Christopher M. Schaupp, Collin C. White, Terrance J. Kavanagh, Edward E. Schmidt and Gary F. Merrill
      Drug Metabolism and Disposition March 2020, 48 (3) 187-197; DOI: https://doi.org/10.1124/dmd.119.089326

X

  1. Xia, Cindy

    1. Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
      Sandeepraj Pusalkar, Xiaofei Zhou, Yuexian Li, Lawrence Cohen, Jun Johnny Yang, Suresh K. Balani, Cindy Xia, Wen Chyi Shyu, Chuang Lu, Karthik Venkatakrishnan and Swapan K. Chowdhury
      Drug Metabolism and Disposition March 2020, 48 (3) 217-229; DOI: https://doi.org/10.1124/dmd.119.087338

Y

  1. Yang, Jun Johnny

    1. Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
      Sandeepraj Pusalkar, Xiaofei Zhou, Yuexian Li, Lawrence Cohen, Jun Johnny Yang, Suresh K. Balani, Cindy Xia, Wen Chyi Shyu, Chuang Lu, Karthik Venkatakrishnan and Swapan K. Chowdhury
      Drug Metabolism and Disposition March 2020, 48 (3) 217-229; DOI: https://doi.org/10.1124/dmd.119.087338

Z

  1. Zhou, Xiaofei

    1. Biotransformation Pathways and Metabolite Profiles of Oral [14C]Alisertib (MLN8237), an Investigational Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
      Sandeepraj Pusalkar, Xiaofei Zhou, Yuexian Li, Lawrence Cohen, Jun Johnny Yang, Suresh K. Balani, Cindy Xia, Wen Chyi Shyu, Chuang Lu, Karthik Venkatakrishnan and Swapan K. Chowdhury
      Drug Metabolism and Disposition March 2020, 48 (3) 217-229; DOI: https://doi.org/10.1124/dmd.119.087338

  2. Zhu, Hao-Jie

    1. Carboxylesterase 1 and Precision Pharmacotherapy: Pharmacogenetics and Nongenetic Regulators
      Lucy Her and Hao-Jie Zhu
      Drug Metabolism and Disposition March 2020, 48 (3) 230-244; DOI: https://doi.org/10.1124/dmd.119.089680
Back to top

In this issue