Research ArticleMinireview
Epigenetic Regulation of Multidrug Resistance Protein 1 and Breast Cancer Resistance Protein Transporters by Histone Deacetylase Inhibition
Dahea You, Jason R. Richardson and Lauren M. Aleksunes
Drug Metabolism and Disposition June 2020, 48 (6) 459-480; DOI: https://doi.org/10.1124/dmd.119.089953
Dahea You
Joint Graduate Program in Toxicology, Rutgers, The State University of New Jersey, Piscataway, New Jersey (D.Y.); Department of Environmental Health Sciences, Robert Stempel School of Public Health and Social Work, Florida International University, Miami, Florida (J.R.R.); Environmental and Occupational Health Sciences Institute, Piscataway, New Jersey (J.R.R., L.M.A.); and Department of Pharmacology and Toxicology, Rutgers, The State University of New Jersey, Ernest Mario School of Pharmacy, Piscataway, New Jersey (L.M.A.)
Jason R. Richardson
Joint Graduate Program in Toxicology, Rutgers, The State University of New Jersey, Piscataway, New Jersey (D.Y.); Department of Environmental Health Sciences, Robert Stempel School of Public Health and Social Work, Florida International University, Miami, Florida (J.R.R.); Environmental and Occupational Health Sciences Institute, Piscataway, New Jersey (J.R.R., L.M.A.); and Department of Pharmacology and Toxicology, Rutgers, The State University of New Jersey, Ernest Mario School of Pharmacy, Piscataway, New Jersey (L.M.A.)
Lauren M. Aleksunes
Joint Graduate Program in Toxicology, Rutgers, The State University of New Jersey, Piscataway, New Jersey (D.Y.); Department of Environmental Health Sciences, Robert Stempel School of Public Health and Social Work, Florida International University, Miami, Florida (J.R.R.); Environmental and Occupational Health Sciences Institute, Piscataway, New Jersey (J.R.R., L.M.A.); and Department of Pharmacology and Toxicology, Rutgers, The State University of New Jersey, Ernest Mario School of Pharmacy, Piscataway, New Jersey (L.M.A.)
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In this issue
Research ArticleMinireview
Histone Deacetylase Inhibition and Transporter Regulation
Dahea You, Jason R. Richardson and Lauren M. Aleksunes
Drug Metabolism and Disposition June 1, 2020, 48 (6) 459-480; DOI: https://doi.org/10.1124/dmd.119.089953
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- Article
- Visual Overview
- Abstract
- Introduction
- Multidrug Resistance Protein 1
- Breast Cancer Resistance Protein
- Epigenetic Regulation by Histone Acetylation
- Histone Acetylation in the Regulation of Efflux Transporters
- Effects of HDAC Inhibitors on the BCRP Transporter
- Potential Mechanisms of HDAC Inhibitor–Mediated Transporter Regulation
- Conclusion and Discussion
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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