Research ArticleArticle
Novel Homodimer Metabolites of GDC-0994 via Cytochrome P450–Catalyzed Radical Coupling
Ryan H. Takahashi, Jessica M. Grandner, Sudheer Bobba, Yanzhou Liu, Paul Beroza, Donglu Zhang and Shuguang Ma
Drug Metabolism and Disposition June 2020, 48 (6) 521-527; DOI: https://doi.org/10.1124/dmd.119.090019
Ryan H. Takahashi
Drug Metabolism and Pharmacokinetics (R.H.T., S.B., D.Z., S.M.) and Discovery Chemistry (J.M.G., Y.L., P.B.), Genentech, Inc., South San Francisco, California
Jessica M. Grandner
Drug Metabolism and Pharmacokinetics (R.H.T., S.B., D.Z., S.M.) and Discovery Chemistry (J.M.G., Y.L., P.B.), Genentech, Inc., South San Francisco, California
Sudheer Bobba
Drug Metabolism and Pharmacokinetics (R.H.T., S.B., D.Z., S.M.) and Discovery Chemistry (J.M.G., Y.L., P.B.), Genentech, Inc., South San Francisco, California
Yanzhou Liu
Drug Metabolism and Pharmacokinetics (R.H.T., S.B., D.Z., S.M.) and Discovery Chemistry (J.M.G., Y.L., P.B.), Genentech, Inc., South San Francisco, California
Paul Beroza
Drug Metabolism and Pharmacokinetics (R.H.T., S.B., D.Z., S.M.) and Discovery Chemistry (J.M.G., Y.L., P.B.), Genentech, Inc., South San Francisco, California
Donglu Zhang
Drug Metabolism and Pharmacokinetics (R.H.T., S.B., D.Z., S.M.) and Discovery Chemistry (J.M.G., Y.L., P.B.), Genentech, Inc., South San Francisco, California
Shuguang Ma
Drug Metabolism and Pharmacokinetics (R.H.T., S.B., D.Z., S.M.) and Discovery Chemistry (J.M.G., Y.L., P.B.), Genentech, Inc., South San Francisco, California
In this issue
Research ArticleArticle
Novel Dimer Metabolites of GDC-0994 Mediated by CYP3A4
Ryan H. Takahashi, Jessica M. Grandner, Sudheer Bobba, Yanzhou Liu, Paul Beroza, Donglu Zhang and Shuguang Ma
Drug Metabolism and Disposition June 1, 2020, 48 (6) 521-527; DOI: https://doi.org/10.1124/dmd.119.090019
Jump to section
Related Articles
Cited By...
More in this TOC Section
Similar Articles
Advertisement