Table of Contents

Articles

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  Regional Proteomic Quantification of Clinically Relevant Non-Cytochrome P450 Enzymes along the Human Small Intestine

  Haeyoung Zhang, Chris Wolford, Abdul Basit, Albert P. Li, Peter W. Fan, Bernard P. Murray, Ryan H. Takahashi, S. Cyrus Khojasteh, Bill J. Smith, Kenneth E. Thummel and Bhagwat Prasad

  Drug Metabolism and Disposition July 2020, 48 (7) 528-536; DOI: https://doi.org/10.1124/dmd.120.090738
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  Are There Any Experimental Perfusion Data that Preferentially Support the Dispersion and Parallel-Tube Models over the Well-Stirred Model of Organ Elimination?

  Jasleen K. Sodhi, Hong-Jaan Wang and Leslie Z. Benet

  Drug Metabolism and Disposition July 2020, 48 (7) 537-543; DOI: https://doi.org/10.1124/dmd.120.090530
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  Nitric Oxide Mediated Degradation of CYP2A6 via the Ubiquitin-Proteasome Pathway in Human Hepatoma Cells

  John Cerrone, Choon-myung Lee, Tian Mi and Edward T. Morgan

  Drug Metabolism and Disposition July 2020, 48 (7) 544-552; DOI: https://doi.org/10.1124/dmd.119.089961
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  Concentration Dependence of the Unbound Partition Coefficient Kp_uu and Its Application to Correct for Exposure-Related Discrepancies between Biochemical and Cellular Potency of KAT6A Inhibitors

  Cornelius Trünkle, Christian Lechner, Daniel Korr, Léa Bouché, Naomi Barak, Amaury Fernández-Montalván, Roderich D Süssmuth and Andreas Reichel

  Drug Metabolism and Disposition July 2020, 48 (7) 553-562; DOI: https://doi.org/10.1124/dmd.120.090563
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  Age-Related Changes in miRNA Expression Influence GSTZ1 and Other Drug Metabolizing Enzymes

  Stephan C. Jahn, Lauren A. Gay, Claire J. Weaver, Rolf Renne, Taimour Y. Langaee, Peter W. Stacpoole and Margaret O. James

  Drug Metabolism and Disposition July 2020, 48 (7) 563-569; DOI: https://doi.org/10.1124/dmd.120.090639
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  Investigating the Role of Altered Systemic Albumin Concentration on the Disposition of Theophylline in Adult and Pediatric Patients with Asthma by Using the Physiologically Based Pharmacokinetic Approach

  Muhammad Fawad Rasool, Ramsha Khalid, Imran Imran, Abdul Majeed, Hamid Saeed, Fawaz Alasmari, Mohammed Mufadhe Alanazi and Faleh Alqahtani

  Drug Metabolism and Disposition July 2020, 48 (7) 570-579; DOI: https://doi.org/10.1124/dmd.120.090969
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  Human Aldehyde Oxidase 1–Mediated Carbazeran Oxidation in Chimeric TK-NOG Mice Transplanted with Human Hepatocytes

  Shotaro Uehara, Nao Yoneda, Yuichiro Higuchi, Hiroshi Yamazaki and Hiroshi Suemizu

  Drug Metabolism and Disposition July 2020, 48 (7) 580-586; DOI: https://doi.org/10.1124/dmd.120.091090
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  Crystalline Sponges as a Sensitive and Fast Method for Metabolite Identification: Application to Gemfibrozil and its Phase I and II Metabolites

  Lara Rosenberger, Carolina von Essen, Anupam Khutia, Clemens Kühn, Klaus Urbahns, Katrin Georgi, Rolf W. Hartmann and Lassina Badolo

  Drug Metabolism and Disposition July 2020, 48 (7) 587-593; DOI: https://doi.org/10.1124/dmd.120.091140
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  Enrichment-free High-throughput Liquid Chromatography–Multiple-Reaction Monitoring Quantification of Cytochrome P450 Proteins in Plated Human Hepatocytes Direct from 96-Well Plates Enables Routine Protein Induction Measurements

  John P. Savaryn, Ning Liu, Jun Sun, Junli Ma, David M. Stresser and Gary Jenkins

  Drug Metabolism and Disposition July 2020, 48 (7) 594-602; DOI: https://doi.org/10.1124/dmd.120.090480
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  Nucleoside Reverse Transcriptase Inhibitor Interaction with Human Equilibrative Nucleoside Transporters 1 and 2

  Siennah R. Miller, Raymond K. Hau, Joseph L. Jilek, Mark N. Morales, Stephen H. Wright and Nathan J. Cherrington

  Drug Metabolism and Disposition July 2020, 48 (7) 603-612; DOI: https://doi.org/10.1124/dmd.120.090720