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Research ArticleArticle

Disposition and Metabolism of [14C]Lemborexant in Healthy Human Subjects and Characterization of Its Circulating Metabolites

Takashi Ueno, Tomomi Ishida, Jagadeesh Aluri, Michiyuki Suzuki, Carsten T. Beuckmann, Takaaki Kameyama, Shoji Asakura and Kazutomi Kusano
Drug Metabolism and Disposition January 2021, 49 (1) 31-38; DOI: https://doi.org/10.1124/dmd.120.000229

Article Information

vol. 49 no. 1 31-38
DOI 
https://doi.org/10.1124/dmd.120.000229
PubMed 
33144331
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 28, 2020
  • Accepted October 26, 2020
  • Published online December 10, 2020.

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Copyright & Usage 
Copyright © 2020 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Takashi Ueno,
  2. Tomomi Ishida,
  3. Jagadeesh Aluri,
  4. Michiyuki Suzuki,
  5. Carsten T. Beuckmann,
  6. Takaaki Kameyama,
  7. Shoji Asakura, and
  8. Kazutomi Kusano
  1. Eisai Co., Ltd., Ibaraki, Japan (T.U., T.I., C.T.B., T.K., S.A., K.K.); Eisai Inc., Woodcliff Lake, New Jersey (J.A.); and EA Pharma Co., Ltd., Tokyo, Japan (M.S.)
  1. Address correspondence to:
    Takashi Ueno, Drug Metabolism and Pharmacokinetics, Eisai Co., Ltd., 5-1-3 Tokodai, Tsukuba, Ibaraki 300-2635, Japan. E-mail: t3-ueno{at}hhc.eisai.co.jp
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ADME Properties of Lemborexant in Humans

Takashi Ueno, Tomomi Ishida, Jagadeesh Aluri, Michiyuki Suzuki, Carsten T. Beuckmann, Takaaki Kameyama, Shoji Asakura and Kazutomi Kusano
Drug Metabolism and Disposition January 1, 2021, 49 (1) 31-38; DOI: https://doi.org/10.1124/dmd.120.000229
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