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Index by author

March 01, 2021; Volume 49,Issue 3

A

  1. Aa, Jiye

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

  2. Abe, Ai

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

  3. Abouda, Arsany A.

    1. Detoxication versus Bioactivation Pathways of Lapatinib In Vitro: UGT1A1 Catalyzes the Hepatic Glucuronidation of Debenzylated Lapatinib
      Dasean T. Nardone-White, Jennifer E. Bissada, Arsany A. Abouda and Klarissa D. Jackson
      Drug Metabolism and Disposition March 2021, 49 (3) 233-244; DOI: https://doi.org/10.1124/dmd.120.000236

B

  1. Bissada, Jennifer E.

    1. Detoxication versus Bioactivation Pathways of Lapatinib In Vitro: UGT1A1 Catalyzes the Hepatic Glucuronidation of Debenzylated Lapatinib
      Dasean T. Nardone-White, Jennifer E. Bissada, Arsany A. Abouda and Klarissa D. Jackson
      Drug Metabolism and Disposition March 2021, 49 (3) 233-244; DOI: https://doi.org/10.1124/dmd.120.000236

  2. Burgess, Laurette

    1. Open Access
      Prediction of Transporter-Mediated Drug-Drug Interactions and Phenotyping of Hepatobiliary Transporters Involved in the Clearance of E7766, a Novel Macrocycle-Bridged Dinucleotide
      Rongrong Jiang, Andrew Hart, Laurette Burgess, Dae-Shik Kim, Weidong George Lai and Vaishali Dixit
      Drug Metabolism and Disposition March 2021, 49 (3) 265-275; DOI: https://doi.org/10.1124/dmd.120.000125

C

  1. Cao, Bei

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

D

  1. Dixit, Vaishali

    1. Open Access
      Prediction of Transporter-Mediated Drug-Drug Interactions and Phenotyping of Hepatobiliary Transporters Involved in the Clearance of E7766, a Novel Macrocycle-Bridged Dinucleotide
      Rongrong Jiang, Andrew Hart, Laurette Burgess, Dae-Shik Kim, Weidong George Lai and Vaishali Dixit
      Drug Metabolism and Disposition March 2021, 49 (3) 265-275; DOI: https://doi.org/10.1124/dmd.120.000125

  2. Dworakowski, Wojciech

    1. Evaluation of the Utility of PXB Chimeric Mice for Predicting Human Liver Partitioning of Hepatic Organic Anion-Transporting Polypeptide Transporter Substrates
      Bo Feng, Rachel Pemberton, Wojciech Dworakowski, Zhengqi Ye, Craig Zetterberg, Guanyu Wang, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition March 2021, 49 (3) 254-264; DOI: https://doi.org/10.1124/dmd.120.000276

F

  1. Fei, Fei

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

  2. Feng, Bo

    1. Evaluation of the Utility of PXB Chimeric Mice for Predicting Human Liver Partitioning of Hepatic Organic Anion-Transporting Polypeptide Transporter Substrates
      Bo Feng, Rachel Pemberton, Wojciech Dworakowski, Zhengqi Ye, Craig Zetterberg, Guanyu Wang, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition March 2021, 49 (3) 254-264; DOI: https://doi.org/10.1124/dmd.120.000276

  3. Feng, Dong

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

  4. Feng, Siqi

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

  5. Francis, L. J.

    1. Impact of Plasma Protein Binding in Drug Clearance Prediction: A Database Analysis of Published Studies and Implications for In Vitro-In Vivo Extrapolation
      L. J. Francis, J. B. Houston and D. Hallifax
      Drug Metabolism and Disposition March 2021, 49 (3) 188-201; DOI: https://doi.org/10.1124/dmd.120.000294

  6. Furge, Kyle A.

    1. Tryptophan-75 Is a Low-Energy Channel-Gating Residue that Facilitates Substrate Egress/Access in Cytochrome P450 2D6
      Tryptophan-75 Is a Low-Energy Channel-Gating Residue that Facilitates Substrate Egress/Access in Cytochrome P450 2D6
      Kevin D. McCarty, Samuel A. Ratliff, Kyle A. Furge and Laura Lowe Furge
      Drug Metabolism and Disposition March 2021, 49 (3) 179-187; DOI: https://doi.org/10.1124/dmd.120.000274

  7. Furge, Laura Lowe

    1. Tryptophan-75 Is a Low-Energy Channel-Gating Residue that Facilitates Substrate Egress/Access in Cytochrome P450 2D6
      Tryptophan-75 Is a Low-Energy Channel-Gating Residue that Facilitates Substrate Egress/Access in Cytochrome P450 2D6
      Kevin D. McCarty, Samuel A. Ratliff, Kyle A. Furge and Laura Lowe Furge
      Drug Metabolism and Disposition March 2021, 49 (3) 179-187; DOI: https://doi.org/10.1124/dmd.120.000274

G

  1. Ge, Chun

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

  2. Guo, Grace L.

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

  3. Gutiérrez Rico, Evelyn Marie

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

H

  1. Hallifax, D.

    1. Impact of Plasma Protein Binding in Drug Clearance Prediction: A Database Analysis of Published Studies and Implications for In Vitro-In Vivo Extrapolation
      L. J. Francis, J. B. Houston and D. Hallifax
      Drug Metabolism and Disposition March 2021, 49 (3) 188-201; DOI: https://doi.org/10.1124/dmd.120.000294

  2. Hart, Andrew

    1. Open Access
      Prediction of Transporter-Mediated Drug-Drug Interactions and Phenotyping of Hepatobiliary Transporters Involved in the Clearance of E7766, a Novel Macrocycle-Bridged Dinucleotide
      Rongrong Jiang, Andrew Hart, Laurette Burgess, Dae-Shik Kim, Weidong George Lai and Vaishali Dixit
      Drug Metabolism and Disposition March 2021, 49 (3) 265-275; DOI: https://doi.org/10.1124/dmd.120.000125

  3. Herpoldt, Karla-Luise

    1. Aldehyde Oxidase Contributes to All-Trans-Retinoic Acid Biosynthesis in Human Liver
      Guo Zhong, Chris J. Seaman, Erickson M. Paragas, Huaqing Xi, Karla-Luise Herpoldt, Neil P. King, Jeffrey P. Jones and Nina Isoherranen
      Drug Metabolism and Disposition March 2021, 49 (3) 202-211; DOI: https://doi.org/10.1124/dmd.120.000296

  4. Hirasawa, Noriyasu

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

  5. Hiratsuka, Masahiro

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

  6. Hirayama, Daisuke

    1. In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      Kazuo Takayama, Kohei Ito, Akiko Matsui, Tomoki Yamashita, Kentaro Kawakami, Daisuke Hirayama, Wataru Kishimoto, Hiroshi Nakase and Hiroyuki Mizuguchi
      Drug Metabolism and Disposition March 2021, 49 (3) 221-232; DOI: https://doi.org/10.1124/dmd.120.000283

  7. Hishinuma, Eiji

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

  8. Houston, J. B.

    1. Impact of Plasma Protein Binding in Drug Clearance Prediction: A Database Analysis of Published Studies and Implications for In Vitro-In Vivo Extrapolation
      L. J. Francis, J. B. Houston and D. Hallifax
      Drug Metabolism and Disposition March 2021, 49 (3) 188-201; DOI: https://doi.org/10.1124/dmd.120.000294

  9. Huang, Jingqiu

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

I

  1. Isoherranen, Nina

    1. Aldehyde Oxidase Contributes to All-Trans-Retinoic Acid Biosynthesis in Human Liver
      Guo Zhong, Chris J. Seaman, Erickson M. Paragas, Huaqing Xi, Karla-Luise Herpoldt, Neil P. King, Jeffrey P. Jones and Nina Isoherranen
      Drug Metabolism and Disposition March 2021, 49 (3) 202-211; DOI: https://doi.org/10.1124/dmd.120.000296

  2. Ito, Kohei

    1. In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      Kazuo Takayama, Kohei Ito, Akiko Matsui, Tomoki Yamashita, Kentaro Kawakami, Daisuke Hirayama, Wataru Kishimoto, Hiroshi Nakase and Hiroyuki Mizuguchi
      Drug Metabolism and Disposition March 2021, 49 (3) 221-232; DOI: https://doi.org/10.1124/dmd.120.000283

J

  1. Jackson, Klarissa D.

    1. Detoxication versus Bioactivation Pathways of Lapatinib In Vitro: UGT1A1 Catalyzes the Hepatic Glucuronidation of Debenzylated Lapatinib
      Dasean T. Nardone-White, Jennifer E. Bissada, Arsany A. Abouda and Klarissa D. Jackson
      Drug Metabolism and Disposition March 2021, 49 (3) 233-244; DOI: https://doi.org/10.1124/dmd.120.000236

  2. Jiang, Rongrong

    1. Open Access
      Prediction of Transporter-Mediated Drug-Drug Interactions and Phenotyping of Hepatobiliary Transporters Involved in the Clearance of E7766, a Novel Macrocycle-Bridged Dinucleotide
      Rongrong Jiang, Andrew Hart, Laurette Burgess, Dae-Shik Kim, Weidong George Lai and Vaishali Dixit
      Drug Metabolism and Disposition March 2021, 49 (3) 265-275; DOI: https://doi.org/10.1124/dmd.120.000125

  3. Jones, Jeffrey P.

    1. Aldehyde Oxidase Contributes to All-Trans-Retinoic Acid Biosynthesis in Human Liver
      Guo Zhong, Chris J. Seaman, Erickson M. Paragas, Huaqing Xi, Karla-Luise Herpoldt, Neil P. King, Jeffrey P. Jones and Nina Isoherranen
      Drug Metabolism and Disposition March 2021, 49 (3) 202-211; DOI: https://doi.org/10.1124/dmd.120.000296

K

  1. Kawakami, Kentaro

    1. In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      Kazuo Takayama, Kohei Ito, Akiko Matsui, Tomoki Yamashita, Kentaro Kawakami, Daisuke Hirayama, Wataru Kishimoto, Hiroshi Nakase and Hiroyuki Mizuguchi
      Drug Metabolism and Disposition March 2021, 49 (3) 221-232; DOI: https://doi.org/10.1124/dmd.120.000283

  2. Kim, Dae-Shik

    1. Open Access
      Prediction of Transporter-Mediated Drug-Drug Interactions and Phenotyping of Hepatobiliary Transporters Involved in the Clearance of E7766, a Novel Macrocycle-Bridged Dinucleotide
      Rongrong Jiang, Andrew Hart, Laurette Burgess, Dae-Shik Kim, Weidong George Lai and Vaishali Dixit
      Drug Metabolism and Disposition March 2021, 49 (3) 265-275; DOI: https://doi.org/10.1124/dmd.120.000125

  3. King, Neil P.

    1. Aldehyde Oxidase Contributes to All-Trans-Retinoic Acid Biosynthesis in Human Liver
      Guo Zhong, Chris J. Seaman, Erickson M. Paragas, Huaqing Xi, Karla-Luise Herpoldt, Neil P. King, Jeffrey P. Jones and Nina Isoherranen
      Drug Metabolism and Disposition March 2021, 49 (3) 202-211; DOI: https://doi.org/10.1124/dmd.120.000296

  4. Kinoshita, Kengo

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

  5. Kishimoto, Wataru

    1. In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      Kazuo Takayama, Kohei Ito, Akiko Matsui, Tomoki Yamashita, Kentaro Kawakami, Daisuke Hirayama, Wataru Kishimoto, Hiroshi Nakase and Hiroyuki Mizuguchi
      Drug Metabolism and Disposition March 2021, 49 (3) 221-232; DOI: https://doi.org/10.1124/dmd.120.000283

  6. Kong, Bo

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

  7. Kumar, Sanjeev

    1. Evaluation of the Utility of PXB Chimeric Mice for Predicting Human Liver Partitioning of Hepatic Organic Anion-Transporting Polypeptide Transporter Substrates
      Bo Feng, Rachel Pemberton, Wojciech Dworakowski, Zhengqi Ye, Craig Zetterberg, Guanyu Wang, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition March 2021, 49 (3) 254-264; DOI: https://doi.org/10.1124/dmd.120.000276

  8. Kumondai, Masaki

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

L

  1. Lai, Weidong George

    1. Open Access
      Prediction of Transporter-Mediated Drug-Drug Interactions and Phenotyping of Hepatobiliary Transporters Involved in the Clearance of E7766, a Novel Macrocycle-Bridged Dinucleotide
      Rongrong Jiang, Andrew Hart, Laurette Burgess, Dae-Shik Kim, Weidong George Lai and Vaishali Dixit
      Drug Metabolism and Disposition March 2021, 49 (3) 265-275; DOI: https://doi.org/10.1124/dmd.120.000125

  2. Lu, Zhenyao

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

M

  1. Maekawa, Masamitsu

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

  2. Mano, Nariyasu

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

  3. Matsui, Akiko

    1. In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      Kazuo Takayama, Kohei Ito, Akiko Matsui, Tomoki Yamashita, Kentaro Kawakami, Daisuke Hirayama, Wataru Kishimoto, Hiroshi Nakase and Hiroyuki Mizuguchi
      Drug Metabolism and Disposition March 2021, 49 (3) 221-232; DOI: https://doi.org/10.1124/dmd.120.000283

  4. McCarty, Kevin D.

    1. Tryptophan-75 Is a Low-Energy Channel-Gating Residue that Facilitates Substrate Egress/Access in Cytochrome P450 2D6
      Tryptophan-75 Is a Low-Energy Channel-Gating Residue that Facilitates Substrate Egress/Access in Cytochrome P450 2D6
      Kevin D. McCarty, Samuel A. Ratliff, Kyle A. Furge and Laura Lowe Furge
      Drug Metabolism and Disposition March 2021, 49 (3) 179-187; DOI: https://doi.org/10.1124/dmd.120.000274

  5. Mizuguchi, Hiroyuki

    1. In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      Kazuo Takayama, Kohei Ito, Akiko Matsui, Tomoki Yamashita, Kentaro Kawakami, Daisuke Hirayama, Wataru Kishimoto, Hiroshi Nakase and Hiroyuki Mizuguchi
      Drug Metabolism and Disposition March 2021, 49 (3) 221-232; DOI: https://doi.org/10.1124/dmd.120.000283

  6. Morikawa, Yoshio

    1. Evaluation of the Utility of PXB Chimeric Mice for Predicting Human Liver Partitioning of Hepatic Organic Anion-Transporting Polypeptide Transporter Substrates
      Bo Feng, Rachel Pemberton, Wojciech Dworakowski, Zhengqi Ye, Craig Zetterberg, Guanyu Wang, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition March 2021, 49 (3) 254-264; DOI: https://doi.org/10.1124/dmd.120.000276

N

  1. Nakase, Hiroshi

    1. In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      Kazuo Takayama, Kohei Ito, Akiko Matsui, Tomoki Yamashita, Kentaro Kawakami, Daisuke Hirayama, Wataru Kishimoto, Hiroshi Nakase and Hiroyuki Mizuguchi
      Drug Metabolism and Disposition March 2021, 49 (3) 221-232; DOI: https://doi.org/10.1124/dmd.120.000283

  2. Nakayoshi, Tomoki

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

  3. Nardone-White, Dasean T.

    1. Detoxication versus Bioactivation Pathways of Lapatinib In Vitro: UGT1A1 Catalyzes the Hepatic Glucuronidation of Debenzylated Lapatinib
      Dasean T. Nardone-White, Jennifer E. Bissada, Arsany A. Abouda and Klarissa D. Jackson
      Drug Metabolism and Disposition March 2021, 49 (3) 233-244; DOI: https://doi.org/10.1124/dmd.120.000236

O

  1. Oda, Akifumi

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

P

  1. Paragas, Erickson M.

    1. Aldehyde Oxidase Contributes to All-Trans-Retinoic Acid Biosynthesis in Human Liver
      Guo Zhong, Chris J. Seaman, Erickson M. Paragas, Huaqing Xi, Karla-Luise Herpoldt, Neil P. King, Jeffrey P. Jones and Nina Isoherranen
      Drug Metabolism and Disposition March 2021, 49 (3) 202-211; DOI: https://doi.org/10.1124/dmd.120.000296

  2. Pemberton, Rachel

    1. Evaluation of the Utility of PXB Chimeric Mice for Predicting Human Liver Partitioning of Hepatic Organic Anion-Transporting Polypeptide Transporter Substrates
      Bo Feng, Rachel Pemberton, Wojciech Dworakowski, Zhengqi Ye, Craig Zetterberg, Guanyu Wang, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition March 2021, 49 (3) 254-264; DOI: https://doi.org/10.1124/dmd.120.000276

R

  1. Ratliff, Samuel A.

    1. Tryptophan-75 Is a Low-Energy Channel-Gating Residue that Facilitates Substrate Egress/Access in Cytochrome P450 2D6
      Tryptophan-75 Is a Low-Energy Channel-Gating Residue that Facilitates Substrate Egress/Access in Cytochrome P450 2D6
      Kevin D. McCarty, Samuel A. Ratliff, Kyle A. Furge and Laura Lowe Furge
      Drug Metabolism and Disposition March 2021, 49 (3) 179-187; DOI: https://doi.org/10.1124/dmd.120.000274

S

  1. Saigusa, Daisuke

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

  2. Saito, Sakae

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

  3. Seaman, Chris J.

    1. Aldehyde Oxidase Contributes to All-Trans-Retinoic Acid Biosynthesis in Human Liver
      Guo Zhong, Chris J. Seaman, Erickson M. Paragas, Huaqing Xi, Karla-Luise Herpoldt, Neil P. King, Jeffrey P. Jones and Nina Isoherranen
      Drug Metabolism and Disposition March 2021, 49 (3) 202-211; DOI: https://doi.org/10.1124/dmd.120.000296

  4. Stresser, David M.

    1. Evaluation of Tissue Stem Cell–Derived Human Intestinal Organoids, a Physiologically Relevant Model to Evaluate Cytochrome P450 Induction in Gut
      Evaluation of Tissue Stem Cell–Derived Human Intestinal Organoids, a Physiologically Relevant Model to Evaluate Cytochrome P450 Induction in Gut
      David M. Stresser, Jun Sun and Sarah S. Wilson
      Drug Metabolism and Disposition March 2021, 49 (3) 245-253; DOI: https://doi.org/10.1124/dmd.120.000281

  5. Sun, Jun

    1. Evaluation of Tissue Stem Cell–Derived Human Intestinal Organoids, a Physiologically Relevant Model to Evaluate Cytochrome P450 Induction in Gut
      Evaluation of Tissue Stem Cell–Derived Human Intestinal Organoids, a Physiologically Relevant Model to Evaluate Cytochrome P450 Induction in Gut
      David M. Stresser, Jun Sun and Sarah S. Wilson
      Drug Metabolism and Disposition March 2021, 49 (3) 245-253; DOI: https://doi.org/10.1124/dmd.120.000281

  6. Sun, Runbin

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

T

  1. Tadaka, Shu

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

  2. Takayama, Kazuo

    1. In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      Kazuo Takayama, Kohei Ito, Akiko Matsui, Tomoki Yamashita, Kentaro Kawakami, Daisuke Hirayama, Wataru Kishimoto, Hiroshi Nakase and Hiroyuki Mizuguchi
      Drug Metabolism and Disposition March 2021, 49 (3) 221-232; DOI: https://doi.org/10.1124/dmd.120.000283

U

  1. Ueda, Akiko

    1. Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6<em>β</em>-Hydroxylation
      Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
      Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261

W

  1. Wang, Guangji

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

  2. Wang, Guanyu

    1. Evaluation of the Utility of PXB Chimeric Mice for Predicting Human Liver Partitioning of Hepatic Organic Anion-Transporting Polypeptide Transporter Substrates
      Bo Feng, Rachel Pemberton, Wojciech Dworakowski, Zhengqi Ye, Craig Zetterberg, Guanyu Wang, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition March 2021, 49 (3) 254-264; DOI: https://doi.org/10.1124/dmd.120.000276

  3. Wilson, Sarah S.

    1. Evaluation of Tissue Stem Cell–Derived Human Intestinal Organoids, a Physiologically Relevant Model to Evaluate Cytochrome P450 Induction in Gut
      Evaluation of Tissue Stem Cell–Derived Human Intestinal Organoids, a Physiologically Relevant Model to Evaluate Cytochrome P450 Induction in Gut
      David M. Stresser, Jun Sun and Sarah S. Wilson
      Drug Metabolism and Disposition March 2021, 49 (3) 245-253; DOI: https://doi.org/10.1124/dmd.120.000281

X

  1. Xi, Huaqing

    1. Aldehyde Oxidase Contributes to All-Trans-Retinoic Acid Biosynthesis in Human Liver
      Guo Zhong, Chris J. Seaman, Erickson M. Paragas, Huaqing Xi, Karla-Luise Herpoldt, Neil P. King, Jeffrey P. Jones and Nina Isoherranen
      Drug Metabolism and Disposition March 2021, 49 (3) 202-211; DOI: https://doi.org/10.1124/dmd.120.000296

  2. Xie, Yuan

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

Y

  1. Yamashita, Tomoki

    1. In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
      Kazuo Takayama, Kohei Ito, Akiko Matsui, Tomoki Yamashita, Kentaro Kawakami, Daisuke Hirayama, Wataru Kishimoto, Hiroshi Nakase and Hiroyuki Mizuguchi
      Drug Metabolism and Disposition March 2021, 49 (3) 221-232; DOI: https://doi.org/10.1124/dmd.120.000283

  2. Yang, Chung S.

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

  3. Yang, Na

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

  4. Ye, Zhengqi

    1. Evaluation of the Utility of PXB Chimeric Mice for Predicting Human Liver Partitioning of Hepatic Organic Anion-Transporting Polypeptide Transporter Substrates
      Bo Feng, Rachel Pemberton, Wojciech Dworakowski, Zhengqi Ye, Craig Zetterberg, Guanyu Wang, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition March 2021, 49 (3) 254-264; DOI: https://doi.org/10.1124/dmd.120.000276

  5. Yu, Xiaoyi

    1. The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis
      Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang and Jiye Aa
      Drug Metabolism and Disposition March 2021, 49 (3) 276-286; DOI: https://doi.org/10.1124/dmd.120.000215

Z

  1. Zetterberg, Craig

    1. Evaluation of the Utility of PXB Chimeric Mice for Predicting Human Liver Partitioning of Hepatic Organic Anion-Transporting Polypeptide Transporter Substrates
      Bo Feng, Rachel Pemberton, Wojciech Dworakowski, Zhengqi Ye, Craig Zetterberg, Guanyu Wang, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition March 2021, 49 (3) 254-264; DOI: https://doi.org/10.1124/dmd.120.000276

  2. Zhong, Guo

    1. Aldehyde Oxidase Contributes to All-Trans-Retinoic Acid Biosynthesis in Human Liver
      Guo Zhong, Chris J. Seaman, Erickson M. Paragas, Huaqing Xi, Karla-Luise Herpoldt, Neil P. King, Jeffrey P. Jones and Nina Isoherranen
      Drug Metabolism and Disposition March 2021, 49 (3) 202-211; DOI: https://doi.org/10.1124/dmd.120.000296
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