Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn

Table of Contents

April 01, 2021; Volume 49,Issue 4

Articles

  • You have access
    In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver
    Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
    Drug Metabolism and Disposition April 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126
  • Open Access
    Revisiting Nonlinear Bosentan Pharmacokinetics by Physiologically Based Pharmacokinetic Modeling: Target Binding, Albeit Not a Major Contributor to Nonlinearity, Can Offer Prediction of Target Occupancy
    Satoshi Koyama, Kota Toshimoto, Wooin Lee, Yasunori Aoki and Yuichi Sugiyama
    Drug Metabolism and Disposition April 2021, 49 (4) 298-304; DOI: https://doi.org/10.1124/dmd.120.000023
  • You have access
    Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
    Shida Qiao, Sisi Feng, Zhitao Wu, Ting He, Chen Ma, Zhaoliang Peng, E. Tian and Guoyu Pan
    Drug Metabolism and Disposition April 2021, 49 (4) 305-313; DOI: https://doi.org/10.1124/dmd.120.000275
  • Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes
    You have access
    Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes
    Paresh P. Chothe, Rachel Pemberton and Niresh Hariparsad
    Drug Metabolism and Disposition April 2021, 49 (4) 314-321; DOI: https://doi.org/10.1124/dmd.120.000057
  • You have access
    Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity
    Keiya Hirosawa, Tatsuki Fukami, Kiyomichi Tashiro, Yoshiyuki Sakai, Fumiya Kisui, Masataka Nakano and Miki Nakajima
    Drug Metabolism and Disposition April 2021, 49 (4) 322-329; DOI: https://doi.org/10.1124/dmd.120.000295
  • You have access
    Evaluation of Tissue Binding in Three Tissues across Five Species and Prediction of Volume of Distribution from Plasma Protein and Tissue Binding with an Existing Model
    Frederick Hsu, Yi-Chen Chen and Fabio Broccatelli
    Drug Metabolism and Disposition April 2021, 49 (4) 330-336; DOI: https://doi.org/10.1124/dmd.120.000337
  • Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
    You have access
    Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
    Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
    Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

Erratum

  • You have access
    Correction to “Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Guidelines on Model Fitting and Recommendations on Time Course for In Vitro CYP Induction Studies Including Impact on Drug Interaction Risk Assessment”
    Drug Metabolism and Disposition April 2021, 49 (4) 344; DOI: https://doi.org/10.1124/dmd.120.000055err
Back to top
PreviousNext

In this issue

Drug Metabolism and Disposition: 49 (4)
Drug Metabolism and Disposition
Vol. 49, Issue 4
1 Apr 2021
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Sign up for alerts

Jump to

  • Articles
  • Erratum
  • Most Cited
  • Most Read
Loading
  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics