Table of Contents

Articles

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  In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver

  Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi

  Drug Metabolism and Disposition April 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126
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  Revisiting Nonlinear Bosentan Pharmacokinetics by Physiologically Based Pharmacokinetic Modeling: Target Binding, Albeit Not a Major Contributor to Nonlinearity, Can Offer Prediction of Target Occupancy

  Satoshi Koyama, Kota Toshimoto, Wooin Lee, Yasunori Aoki and Yuichi Sugiyama

  Drug Metabolism and Disposition April 2021, 49 (4) 298-304; DOI: https://doi.org/10.1124/dmd.120.000023
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  Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity

  Shida Qiao, Sisi Feng, Zhitao Wu, Ting He, Chen Ma, Zhaoliang Peng, E. Tian and Guoyu Pan

  Drug Metabolism and Disposition April 2021, 49 (4) 305-313; DOI: https://doi.org/10.1124/dmd.120.000275
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  Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes

  Paresh P. Chothe, Rachel Pemberton and Niresh Hariparsad

  Drug Metabolism and Disposition April 2021, 49 (4) 314-321; DOI: https://doi.org/10.1124/dmd.120.000057
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  Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity

  Keiya Hirosawa, Tatsuki Fukami, Kiyomichi Tashiro, Yoshiyuki Sakai, Fumiya Kisui, Masataka Nakano and Miki Nakajima

  Drug Metabolism and Disposition April 2021, 49 (4) 322-329; DOI: https://doi.org/10.1124/dmd.120.000295
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  Evaluation of Tissue Binding in Three Tissues across Five Species and Prediction of Volume of Distribution from Plasma Protein and Tissue Binding with an Existing Model

  Frederick Hsu, Yi-Chen Chen and Fabio Broccatelli

  Drug Metabolism and Disposition April 2021, 49 (4) 330-336; DOI: https://doi.org/10.1124/dmd.120.000337
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  Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice

  Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama

  Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270