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Index by author

April 01, 2021; Volume 49,Issue 4

A

  1. Aoki, Yasunori

    1. Open Access
      Revisiting Nonlinear Bosentan Pharmacokinetics by Physiologically Based Pharmacokinetic Modeling: Target Binding, Albeit Not a Major Contributor to Nonlinearity, Can Offer Prediction of Target Occupancy
      Satoshi Koyama, Kota Toshimoto, Wooin Lee, Yasunori Aoki and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 298-304; DOI: https://doi.org/10.1124/dmd.120.000023

  2. Ariumi, Mashu

    1. Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

B

  1. Broccatelli, Fabio

    1. Evaluation of Tissue Binding in Three Tissues across Five Species and Prediction of Volume of Distribution from Plasma Protein and Tissue Binding with an Existing Model
      Frederick Hsu, Yi-Chen Chen and Fabio Broccatelli
      Drug Metabolism and Disposition April 2021, 49 (4) 330-336; DOI: https://doi.org/10.1124/dmd.120.000337

C

  1. Chen, Yi-Chen

    1. Evaluation of Tissue Binding in Three Tissues across Five Species and Prediction of Volume of Distribution from Plasma Protein and Tissue Binding with an Existing Model
      Frederick Hsu, Yi-Chen Chen and Fabio Broccatelli
      Drug Metabolism and Disposition April 2021, 49 (4) 330-336; DOI: https://doi.org/10.1124/dmd.120.000337

  2. Chothe, Paresh P.

    1. Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes
      Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes
      Paresh P. Chothe, Rachel Pemberton and Niresh Hariparsad
      Drug Metabolism and Disposition April 2021, 49 (4) 314-321; DOI: https://doi.org/10.1124/dmd.120.000057

F

  1. Feng, Sisi

    1. Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
      Shida Qiao, Sisi Feng, Zhitao Wu, Ting He, Chen Ma, Zhaoliang Peng, E. Tian and Guoyu Pan
      Drug Metabolism and Disposition April 2021, 49 (4) 305-313; DOI: https://doi.org/10.1124/dmd.120.000275

  2. Fukami, Tatsuki

    1. Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity
      Keiya Hirosawa, Tatsuki Fukami, Kiyomichi Tashiro, Yoshiyuki Sakai, Fumiya Kisui, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition April 2021, 49 (4) 322-329; DOI: https://doi.org/10.1124/dmd.120.000295

H

  1. Harada, Shohei

    1. Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

  2. Hariparsad, Niresh

    1. Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes
      Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes
      Paresh P. Chothe, Rachel Pemberton and Niresh Hariparsad
      Drug Metabolism and Disposition April 2021, 49 (4) 314-321; DOI: https://doi.org/10.1124/dmd.120.000057

  3. Hatogai, Jo

    1. Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

  4. He, Ting

    1. Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
      Shida Qiao, Sisi Feng, Zhitao Wu, Ting He, Chen Ma, Zhaoliang Peng, E. Tian and Guoyu Pan
      Drug Metabolism and Disposition April 2021, 49 (4) 305-313; DOI: https://doi.org/10.1124/dmd.120.000275

  5. Hira, Daiki

    1. In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver
      Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
      Drug Metabolism and Disposition April 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126

  6. Hirosawa, Keiya

    1. Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity
      Keiya Hirosawa, Tatsuki Fukami, Kiyomichi Tashiro, Yoshiyuki Sakai, Fumiya Kisui, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition April 2021, 49 (4) 322-329; DOI: https://doi.org/10.1124/dmd.120.000295

  7. Hsu, Frederick

    1. Evaluation of Tissue Binding in Three Tissues across Five Species and Prediction of Volume of Distribution from Plasma Protein and Tissue Binding with an Existing Model
      Frederick Hsu, Yi-Chen Chen and Fabio Broccatelli
      Drug Metabolism and Disposition April 2021, 49 (4) 330-336; DOI: https://doi.org/10.1124/dmd.120.000337

I

  1. Iizuka, Misa

    1. Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

  2. Ikeda, Yoshito

    1. In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver
      Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
      Drug Metabolism and Disposition April 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126

K

  1. Katsube, Yurie

    1. In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver
      Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
      Drug Metabolism and Disposition April 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126

  2. Kawamura, Taisuke

    1. Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

  3. Kisui, Fumiya

    1. Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity
      Keiya Hirosawa, Tatsuki Fukami, Kiyomichi Tashiro, Yoshiyuki Sakai, Fumiya Kisui, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition April 2021, 49 (4) 322-329; DOI: https://doi.org/10.1124/dmd.120.000295

  4. Kitaoka, Satoshi

    1. Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

  5. Koide, Hiroyoshi

    1. In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver
      Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
      Drug Metabolism and Disposition April 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126

  6. Koyama, Satoshi

    1. Open Access
      Revisiting Nonlinear Bosentan Pharmacokinetics by Physiologically Based Pharmacokinetic Modeling: Target Binding, Albeit Not a Major Contributor to Nonlinearity, Can Offer Prediction of Target Occupancy
      Satoshi Koyama, Kota Toshimoto, Wooin Lee, Yasunori Aoki and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 298-304; DOI: https://doi.org/10.1124/dmd.120.000023

L

  1. Lee, Wooin

    1. Open Access
      Revisiting Nonlinear Bosentan Pharmacokinetics by Physiologically Based Pharmacokinetic Modeling: Target Binding, Albeit Not a Major Contributor to Nonlinearity, Can Offer Prediction of Target Occupancy
      Satoshi Koyama, Kota Toshimoto, Wooin Lee, Yasunori Aoki and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 298-304; DOI: https://doi.org/10.1124/dmd.120.000023

M

  1. Ma, Chen

    1. Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
      Shida Qiao, Sisi Feng, Zhitao Wu, Ting He, Chen Ma, Zhaoliang Peng, E. Tian and Guoyu Pan
      Drug Metabolism and Disposition April 2021, 49 (4) 305-313; DOI: https://doi.org/10.1124/dmd.120.000275

  2. Minegaki, Tetsuya

    1. In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver
      Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
      Drug Metabolism and Disposition April 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126

  3. Morita, Shin-ya

    1. In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver
      Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
      Drug Metabolism and Disposition April 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126

N

  1. Nagai, Tomomi

    1. Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

  2. Nakajima, Miki

    1. Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity
      Keiya Hirosawa, Tatsuki Fukami, Kiyomichi Tashiro, Yoshiyuki Sakai, Fumiya Kisui, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition April 2021, 49 (4) 322-329; DOI: https://doi.org/10.1124/dmd.120.000295

  3. Nakano, Masataka

    1. Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity
      Keiya Hirosawa, Tatsuki Fukami, Kiyomichi Tashiro, Yoshiyuki Sakai, Fumiya Kisui, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition April 2021, 49 (4) 322-329; DOI: https://doi.org/10.1124/dmd.120.000295

  4. Nishiguchi, Kohshi

    1. In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver
      Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
      Drug Metabolism and Disposition April 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126

O

  1. Ochiai, Wataru

    1. Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

P

  1. Pan, Guoyu

    1. Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
      Shida Qiao, Sisi Feng, Zhitao Wu, Ting He, Chen Ma, Zhaoliang Peng, E. Tian and Guoyu Pan
      Drug Metabolism and Disposition April 2021, 49 (4) 305-313; DOI: https://doi.org/10.1124/dmd.120.000275

  2. Pemberton, Rachel

    1. Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes
      Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes
      Paresh P. Chothe, Rachel Pemberton and Niresh Hariparsad
      Drug Metabolism and Disposition April 2021, 49 (4) 314-321; DOI: https://doi.org/10.1124/dmd.120.000057

  3. Peng, Zhaoliang

    1. Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
      Shida Qiao, Sisi Feng, Zhitao Wu, Ting He, Chen Ma, Zhaoliang Peng, E. Tian and Guoyu Pan
      Drug Metabolism and Disposition April 2021, 49 (4) 305-313; DOI: https://doi.org/10.1124/dmd.120.000275

Q

  1. Qiao, Shida

    1. Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
      Shida Qiao, Sisi Feng, Zhitao Wu, Ting He, Chen Ma, Zhaoliang Peng, E. Tian and Guoyu Pan
      Drug Metabolism and Disposition April 2021, 49 (4) 305-313; DOI: https://doi.org/10.1124/dmd.120.000275

S

  1. Sakai, Yoshiyuki

    1. Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity
      Keiya Hirosawa, Tatsuki Fukami, Kiyomichi Tashiro, Yoshiyuki Sakai, Fumiya Kisui, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition April 2021, 49 (4) 322-329; DOI: https://doi.org/10.1124/dmd.120.000295

  2. Sasatsu, Masanaho

    1. Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

  3. Sugiyama, Kiyoshi

    1. Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

  4. Sugiyama, Yuichi

    1. Open Access
      Revisiting Nonlinear Bosentan Pharmacokinetics by Physiologically Based Pharmacokinetic Modeling: Target Binding, Albeit Not a Major Contributor to Nonlinearity, Can Offer Prediction of Target Occupancy
      Satoshi Koyama, Kota Toshimoto, Wooin Lee, Yasunori Aoki and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 298-304; DOI: https://doi.org/10.1124/dmd.120.000023

T

  1. Takano, Seiya

    1. Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
      Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

  2. Tashiro, Kiyomichi

    1. Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity
      Keiya Hirosawa, Tatsuki Fukami, Kiyomichi Tashiro, Yoshiyuki Sakai, Fumiya Kisui, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition April 2021, 49 (4) 322-329; DOI: https://doi.org/10.1124/dmd.120.000295

  3. Terada, Tomohiro

    1. In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver
      Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
      Drug Metabolism and Disposition April 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126

  4. Tian, E.

    1. Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
      Shida Qiao, Sisi Feng, Zhitao Wu, Ting He, Chen Ma, Zhaoliang Peng, E. Tian and Guoyu Pan
      Drug Metabolism and Disposition April 2021, 49 (4) 305-313; DOI: https://doi.org/10.1124/dmd.120.000275

  5. Toshimoto, Kota

    1. Open Access
      Revisiting Nonlinear Bosentan Pharmacokinetics by Physiologically Based Pharmacokinetic Modeling: Target Binding, Albeit Not a Major Contributor to Nonlinearity, Can Offer Prediction of Target Occupancy
      Satoshi Koyama, Kota Toshimoto, Wooin Lee, Yasunori Aoki and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2021, 49 (4) 298-304; DOI: https://doi.org/10.1124/dmd.120.000023

  6. Tsujimoto, Masayuki

    1. In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver
      Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
      Drug Metabolism and Disposition April 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126

W

  1. Wu, Zhitao

    1. Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
      Shida Qiao, Sisi Feng, Zhitao Wu, Ting He, Chen Ma, Zhaoliang Peng, E. Tian and Guoyu Pan
      Drug Metabolism and Disposition April 2021, 49 (4) 305-313; DOI: https://doi.org/10.1124/dmd.120.000275
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