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Research ArticleArticle

Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice

Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
Drug Metabolism and Disposition April 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270
Wataru Ochiai
Department of Pharmacokinetics (W.O., S.K., T.K., J.H., S.H., M.I., M.A., S.T., T.N.), Laboratory of Tissue Regeneration (M.S.), and Department of Functional Molecule Kinetics (K.S.), School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan
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Satoshi Kitaoka
Department of Pharmacokinetics (W.O., S.K., T.K., J.H., S.H., M.I., M.A., S.T., T.N.), Laboratory of Tissue Regeneration (M.S.), and Department of Functional Molecule Kinetics (K.S.), School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan
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Taisuke Kawamura
Department of Pharmacokinetics (W.O., S.K., T.K., J.H., S.H., M.I., M.A., S.T., T.N.), Laboratory of Tissue Regeneration (M.S.), and Department of Functional Molecule Kinetics (K.S.), School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan
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Jo Hatogai
Department of Pharmacokinetics (W.O., S.K., T.K., J.H., S.H., M.I., M.A., S.T., T.N.), Laboratory of Tissue Regeneration (M.S.), and Department of Functional Molecule Kinetics (K.S.), School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan
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Shohei Harada
Department of Pharmacokinetics (W.O., S.K., T.K., J.H., S.H., M.I., M.A., S.T., T.N.), Laboratory of Tissue Regeneration (M.S.), and Department of Functional Molecule Kinetics (K.S.), School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan
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Misa Iizuka
Department of Pharmacokinetics (W.O., S.K., T.K., J.H., S.H., M.I., M.A., S.T., T.N.), Laboratory of Tissue Regeneration (M.S.), and Department of Functional Molecule Kinetics (K.S.), School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan
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Mashu Ariumi
Department of Pharmacokinetics (W.O., S.K., T.K., J.H., S.H., M.I., M.A., S.T., T.N.), Laboratory of Tissue Regeneration (M.S.), and Department of Functional Molecule Kinetics (K.S.), School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan
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Seiya Takano
Department of Pharmacokinetics (W.O., S.K., T.K., J.H., S.H., M.I., M.A., S.T., T.N.), Laboratory of Tissue Regeneration (M.S.), and Department of Functional Molecule Kinetics (K.S.), School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan
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Tomomi Nagai
Department of Pharmacokinetics (W.O., S.K., T.K., J.H., S.H., M.I., M.A., S.T., T.N.), Laboratory of Tissue Regeneration (M.S.), and Department of Functional Molecule Kinetics (K.S.), School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan
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Masanaho Sasatsu
Department of Pharmacokinetics (W.O., S.K., T.K., J.H., S.H., M.I., M.A., S.T., T.N.), Laboratory of Tissue Regeneration (M.S.), and Department of Functional Molecule Kinetics (K.S.), School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan
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Kiyoshi Sugiyama
Department of Pharmacokinetics (W.O., S.K., T.K., J.H., S.H., M.I., M.A., S.T., T.N.), Laboratory of Tissue Regeneration (M.S.), and Department of Functional Molecule Kinetics (K.S.), School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan
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Article Information

vol. 49 no. 4 337-343
DOI 
https://doi.org/10.1124/dmd.120.000270
PubMed 
33531413

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received October 2, 2020
  • Accepted January 25, 2021
  • Published online March 12, 2021.

Article Versions

  • Earlier version (February 2, 2021 - 07:55).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2021 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Wataru Ochiai,
  2. Satoshi Kitaoka,
  3. Taisuke Kawamura,
  4. Jo Hatogai,
  5. Shohei Harada,
  6. Misa Iizuka,
  7. Mashu Ariumi,
  8. Seiya Takano,
  9. Tomomi Nagai,
  10. Masanaho Sasatsu, and
  11. Kiyoshi Sugiyama
  1. Department of Pharmacokinetics (W.O., S.K., T.K., J.H., S.H., M.I., M.A., S.T., T.N.), Laboratory of Tissue Regeneration (M.S.), and Department of Functional Molecule Kinetics (K.S.), School of Pharmacy and Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan
  1. Address correspondence to:
    Dr. Wataru Ochiai, Department of Pharmacokinetics, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan. E-mail: w-ochiai{at}hoshi.ac.jp
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Drug Metabolism and Disposition: 49 (4)
Drug Metabolism and Disposition
Vol. 49, Issue 4
1 Apr 2021
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Research ArticleArticle

Fetal Pharmacokinetics of Cannabidiol in Second Trimester

Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
Drug Metabolism and Disposition April 1, 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270

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Research ArticleArticle

Fetal Pharmacokinetics of Cannabidiol in Second Trimester

Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama
Drug Metabolism and Disposition April 1, 2021, 49 (4) 337-343; DOI: https://doi.org/10.1124/dmd.120.000270
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