Primary Human Hepatocyte Spheroids as an In Vitro Tool for Investigating Drug Compounds with Low Hepatic Clearance

Julia Riede; Birgit M. Wollmann; Espen Molden; Magnus Ingelman-Sundberg

doi:10.1124/dmd.120.000340

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Primary Human Hepatocyte Spheroids as an In Vitro Tool for Investigating Drug Compounds with Low Hepatic Clearance

Julia Riede, Birgit M. Wollmann, Espen Molden and Magnus Ingelman-Sundberg

Drug Metabolism and Disposition July 2021, 49 (7) 501-508; DOI: https://doi.org/10.1124/dmd.120.000340

Julia Riede

Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (J.R., M.I.-S.); and Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway (B.M.W., E.M.)

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Birgit M. Wollmann

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Espen Molden

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Magnus Ingelman-Sundberg

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Drug Metabolism and Disposition

Vol. 49, Issue 7

1 Jul 2021

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Research ArticleArticle

Clearance Predictions Using Human Hepatocyte Spheroids

Julia Riede, Birgit M. Wollmann, Espen Molden and Magnus Ingelman-Sundberg

Drug Metabolism and Disposition July 1, 2021, 49 (7) 501-508; DOI: https://doi.org/10.1124/dmd.120.000340

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Research ArticleArticle

Clearance Predictions Using Human Hepatocyte Spheroids

Julia Riede, Birgit M. Wollmann, Espen Molden and Magnus Ingelman-Sundberg

Drug Metabolism and Disposition July 1, 2021, 49 (7) 501-508; DOI: https://doi.org/10.1124/dmd.120.000340

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