Research ArticleArticle
Open Access
Primary Human Hepatocyte Spheroids as an In Vitro Tool for Investigating Drug Compounds with Low Hepatic Clearance
Julia Riede, Birgit M. Wollmann, Espen Molden and Magnus Ingelman-Sundberg
Drug Metabolism and Disposition July 2021, 49 (7) 501-508; DOI: https://doi.org/10.1124/dmd.120.000340
Julia Riede
Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (J.R., M.I.-S.); and Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway (B.M.W., E.M.)
Birgit M. Wollmann
Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (J.R., M.I.-S.); and Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway (B.M.W., E.M.)
Espen Molden
Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (J.R., M.I.-S.); and Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway (B.M.W., E.M.)
Magnus Ingelman-Sundberg
Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (J.R., M.I.-S.); and Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway (B.M.W., E.M.)

Submit a Response to This Article
Jump to comment:
No eLetters have been published for this article.
In this issue
Research ArticleArticle
Clearance Predictions Using Human Hepatocyte Spheroids
Julia Riede, Birgit M. Wollmann, Espen Molden and Magnus Ingelman-Sundberg
Drug Metabolism and Disposition July 1, 2021, 49 (7) 501-508; DOI: https://doi.org/10.1124/dmd.120.000340
Jump to section
Related Articles
Cited By...
More in this TOC Section
Similar Articles
Advertisement