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Index by author

September 01, 2021; Volume 49,Issue 9

A

  1. Aa, Jiye

    1. Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Ran Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan Xie
      Drug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438

  2. Alwayn, I. P. J.

    1. Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      Open Access
      Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      L. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de Steeg
      Drug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521

  3. Anderl, Janet L.

    1. Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Open Access
      Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Ying Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai Wang
      Drug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307

  4. Andriopoulou, Christina E.

    1. Oleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
      Oleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
      Foteini Malliou, Christina E. Andriopoulou, Frank J. Gonzalez, Aristeidis Kofinas, Alexios-Leandros Skaltsounis and Maria Konstandi
      Drug Metabolism and Disposition September 2021, 49 (9) 833-843; DOI: https://doi.org/10.1124/dmd.120.000302

B

  1. Badee, Justine

    1. Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes
      Ryan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen Fowler
      Drug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474

C

  1. Chothe, P. P.

    1. Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      Open Access
      Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      L. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de Steeg
      Drug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521

  2. Chowdhury, S. K.

    1. Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      Open Access
      Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      L. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de Steeg
      Drug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521

  3. Collier, Abby C.

    1. Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes
      Ryan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen Fowler
      Drug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474

D

  1. Deng, Feng

    1. Comparative Hepatic and Intestinal Efflux Transport of Statins
      Open Access
      Comparative Hepatic and Intestinal Efflux Transport of Statins
      Feng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko Niemi
      Drug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430

  2. Donkers, J. M.

    1. Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      Open Access
      Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      L. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de Steeg
      Drug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521

F

  1. Fang, Ying

    1. Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Open Access
      Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Ying Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai Wang
      Drug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307

  2. Filppula, Anne M.

    1. Comparative Hepatic and Intestinal Efflux Transport of Statins
      Open Access
      Comparative Hepatic and Intestinal Efflux Transport of Statins
      Feng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko Niemi
      Drug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430

  3. Forrest, William F.

    1. Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes
      Ryan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen Fowler
      Drug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474

  4. Fowler, Stephen

    1. Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes
      Ryan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen Fowler
      Drug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474

  5. Fujita, Daichi

    1. MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/<em>SLCO2B1</em> in Caco-2 Cells
      MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 Cells
      Hisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi Tamai
      Drug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380

  6. Fukami, Tatsuki

    1. Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans
      Shiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki Nakajima
      Drug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513

G

  1. Garrido, Claudia

    1. The Inactivation of Human Aldehyde Oxidase 1 by Hydrogen Peroxide and Superoxide
      Claudia Garrido and Silke Leimkühler
      Drug Metabolism and Disposition September 2021, 49 (9) 729-735; DOI: https://doi.org/10.1124/dmd.121.000549

  2. Gonzalez, Eric

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

  3. Gonzalez, Frank J.

    1. Oleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
      Oleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
      Foteini Malliou, Christina E. Andriopoulou, Frank J. Gonzalez, Aristeidis Kofinas, Alexios-Leandros Skaltsounis and Maria Konstandi
      Drug Metabolism and Disposition September 2021, 49 (9) 833-843; DOI: https://doi.org/10.1124/dmd.120.000302

H

  1. Hammock, Bruce D.

    1. Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Open Access
      Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Ying Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai Wang
      Drug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307

  2. Heyward, Scott

    1. Open Access
      Contribution of Extrahepatic Aldehyde Oxidase Activity to Human Clearance
      Kirk D. Kozminski, Jangir Selimkhanov, Scott Heyward and Michael A. Zientek
      Drug Metabolism and Disposition September 2021, 49 (9) 743-749; DOI: https://doi.org/10.1124/dmd.120.000313

  3. Hirosawa, Keiya

    1. Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans
      Shiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki Nakajima
      Drug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513

  4. Hirvensalo, Päivi

    1. Comparative Hepatic and Intestinal Efflux Transport of Statins
      Open Access
      Comparative Hepatic and Intestinal Efflux Transport of Statins
      Feng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko Niemi
      Drug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430

  5. Honda, Shiori

    1. Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans
      Shiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki Nakajima
      Drug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513

  6. Hop, Cornelis E. C. A.

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

  7. Huang, Ruili

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

I

  1. Iwamoto, Yui

    1. MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/<em>SLCO2B1</em> in Caco-2 Cells
      MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 Cells
      Hisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi Tamai
      Drug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380

J

  1. Jain, Sankalp

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

  2. Johnson, Henry

    1. Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Open Access
      Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Ying Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai Wang
      Drug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307

  3. Jones, Barry

    1. Impact of Interindividual Differences in Plasma Fraction Unbound on the Pharmacokinetics of a Novel Syk Kinase Inhibitor in Beagle Dogs
      Andy Pike, Barry Jones, Roshini Markandu and Daniel O’Neill
      Drug Metabolism and Disposition September 2021, 49 (9) 736-742; DOI: https://doi.org/10.1124/dmd.121.000409

K

  1. Kirk, Christopher

    1. Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Open Access
      Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Ying Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai Wang
      Drug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307

  2. Knibbe, C. A. J.

    1. Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      Open Access
      Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      L. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de Steeg
      Drug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521

  3. Kofinas, Aristeidis

    1. Oleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
      Oleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
      Foteini Malliou, Christina E. Andriopoulou, Frank J. Gonzalez, Aristeidis Kofinas, Alexios-Leandros Skaltsounis and Maria Konstandi
      Drug Metabolism and Disposition September 2021, 49 (9) 833-843; DOI: https://doi.org/10.1124/dmd.120.000302

  4. Komori, Hisakazu

    1. MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/<em>SLCO2B1</em> in Caco-2 Cells
      MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 Cells
      Hisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi Tamai
      Drug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380

  5. Konstandi, Maria

    1. Oleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
      Oleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
      Foteini Malliou, Christina E. Andriopoulou, Frank J. Gonzalez, Aristeidis Kofinas, Alexios-Leandros Skaltsounis and Maria Konstandi
      Drug Metabolism and Disposition September 2021, 49 (9) 833-843; DOI: https://doi.org/10.1124/dmd.120.000302

  6. Kozminski, Kirk D.

    1. Open Access
      Contribution of Extrahepatic Aldehyde Oxidase Activity to Human Clearance
      Kirk D. Kozminski, Jangir Selimkhanov, Scott Heyward and Michael A. Zientek
      Drug Metabolism and Disposition September 2021, 49 (9) 743-749; DOI: https://doi.org/10.1124/dmd.120.000313

  7. Kulju, Sami

    1. Comparative Hepatic and Intestinal Efflux Transport of Statins
      Open Access
      Comparative Hepatic and Intestinal Efflux Transport of Statins
      Feng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko Niemi
      Drug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430

L

  1. Leimkühler, Silke

    1. The Inactivation of Human Aldehyde Oxidase 1 by Hydrogen Peroxide and Superoxide
      Claudia Garrido and Silke Leimkühler
      Drug Metabolism and Disposition September 2021, 49 (9) 729-735; DOI: https://doi.org/10.1124/dmd.121.000549

  2. Li, Albert P.

    1. Messenger RNA Expression of Albumin, Transferrin, Transthyretin, Asialoglycoprotein Receptor, Cytochrome P450 Isoform, Uptake Transporter, and Efflux Transporter Genes as a Function of Culture Duration in Prolonged Cultured Cryopreserved Human Hepatocytes as Collagen-Matrigel Sandwich Cultures: Evidence for Redifferentiation upon Prolonged Culturing
      Qian Yang and Albert P. Li
      Drug Metabolism and Disposition September 2021, 49 (9) 790-802; DOI: https://doi.org/10.1124/dmd.121.000424

  3. Lou, Yunge

    1. Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Ran Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan Xie
      Drug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438

M

  1. Malliou, Foteini

    1. Oleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
      Oleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
      Foteini Malliou, Christina E. Andriopoulou, Frank J. Gonzalez, Aristeidis Kofinas, Alexios-Leandros Skaltsounis and Maria Konstandi
      Drug Metabolism and Disposition September 2021, 49 (9) 833-843; DOI: https://doi.org/10.1124/dmd.120.000302

  2. Markandu, Roshini

    1. Impact of Interindividual Differences in Plasma Fraction Unbound on the Pharmacokinetics of a Novel Syk Kinase Inhibitor in Beagle Dogs
      Andy Pike, Barry Jones, Roshini Markandu and Daniel O’Neill
      Drug Metabolism and Disposition September 2021, 49 (9) 736-742; DOI: https://doi.org/10.1124/dmd.121.000409

  3. McMinn, Dustin

    1. Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Open Access
      Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Ying Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai Wang
      Drug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307

  4. Morisseau, Christophe

    1. Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Open Access
      Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Ying Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai Wang
      Drug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307

  5. Muchamuel, Tony

    1. Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Open Access
      Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Ying Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai Wang
      Drug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307

N

  1. Nakajima, Miki

    1. Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans
      Shiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki Nakajima
      Drug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513
    2. MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/<em>SLCO2B1</em> in Caco-2 Cells
      MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 Cells
      Hisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi Tamai
      Drug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380

  2. Nakanishi, Takeo

    1. MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/<em>SLCO2B1</em> in Caco-2 Cells
      MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 Cells
      Hisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi Tamai
      Drug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380

  3. Nakano, Masataka

    1. Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans
      Shiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki Nakajima
      Drug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513

  4. Neuvonen, Mikko

    1. Comparative Hepatic and Intestinal Efflux Transport of Statins
      Open Access
      Comparative Hepatic and Intestinal Efflux Transport of Statins
      Feng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko Niemi
      Drug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430

  5. Nguyễn, Ðắc-Trung

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

  6. Niemi, Mikko

    1. Comparative Hepatic and Intestinal Efflux Transport of Statins
      Open Access
      Comparative Hepatic and Intestinal Efflux Transport of Statins
      Feng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko Niemi
      Drug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430

O

  1. O’Neill, Daniel

    1. Impact of Interindividual Differences in Plasma Fraction Unbound on the Pharmacokinetics of a Novel Syk Kinase Inhibitor in Beagle Dogs
      Andy Pike, Barry Jones, Roshini Markandu and Daniel O’Neill
      Drug Metabolism and Disposition September 2021, 49 (9) 736-742; DOI: https://doi.org/10.1124/dmd.121.000409

  2. Obach, R. Scott

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

  3. Oswald, Stefan

    1. Comparative Hepatic and Intestinal Efflux Transport of Statins
      Open Access
      Comparative Hepatic and Intestinal Efflux Transport of Statins
      Feng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko Niemi
      Drug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430

P

  1. Parrott, Neil

    1. Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes
      Ryan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen Fowler
      Drug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474

  2. Pike, Andy

    1. Impact of Interindividual Differences in Plasma Fraction Unbound on the Pharmacokinetics of a Novel Syk Kinase Inhibitor in Beagle Dogs
      Andy Pike, Barry Jones, Roshini Markandu and Daniel O’Neill
      Drug Metabolism and Disposition September 2021, 49 (9) 736-742; DOI: https://doi.org/10.1124/dmd.121.000409

Q

  1. Qiu, NaHong

    1. Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes
      Ryan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen Fowler
      Drug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474

S

  1. Sakamuru, Srilatha

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

  2. Schmidt, Stephan

    1. Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes
      Ryan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen Fowler
      Drug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474

  3. Selimkhanov, Jangir

    1. Open Access
      Contribution of Extrahepatic Aldehyde Oxidase Activity to Human Clearance
      Kirk D. Kozminski, Jangir Selimkhanov, Scott Heyward and Michael A. Zientek
      Drug Metabolism and Disposition September 2021, 49 (9) 743-749; DOI: https://doi.org/10.1124/dmd.120.000313

  4. Shah, Pranav

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

  5. Shirasaki, Yuma

    1. MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/<em>SLCO2B1</em> in Caco-2 Cells
      MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 Cells
      Hisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi Tamai
      Drug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380

  6. Simeonov, Anton

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

  7. Skaltsounis, Alexios-Leandros

    1. Oleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
      Oleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
      Foteini Malliou, Christina E. Andriopoulou, Frank J. Gonzalez, Aristeidis Kofinas, Alexios-Leandros Skaltsounis and Maria Konstandi
      Drug Metabolism and Disposition September 2021, 49 (9) 833-843; DOI: https://doi.org/10.1124/dmd.120.000302

  8. Smith, Alexander D.

    1. Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes
      Ryan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen Fowler
      Drug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474

  9. Stevens, L. J.

    1. Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      Open Access
      Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      L. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de Steeg
      Drug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521

T

  1. Takahashi, Ryan H.

    1. Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes
      Ryan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen Fowler
      Drug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474

  2. Tamai, Ikumi

    1. MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/<em>SLCO2B1</em> in Caco-2 Cells
      MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 Cells
      Hisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi Tamai
      Drug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380

  3. Torimoto-Katori, Nao

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

  4. Tsujiguchi, Takuya

    1. Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans
      Shiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki Nakajima
      Drug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513

  5. Tuomi, Suvi-Kukka

    1. Comparative Hepatic and Intestinal Efflux Transport of Statins
      Open Access
      Comparative Hepatic and Intestinal Efflux Transport of Statins
      Feng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko Niemi
      Drug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430

U

  1. Uehara, Shotaro

    1. Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans
      Shiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki Nakajima
      Drug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513

  2. Uno, Yasuhiro

    1. Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans
      Shiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki Nakajima
      Drug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513

V

  1. Vaes, W. H. J.

    1. Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      Open Access
      Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      L. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de Steeg
      Drug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521

  2. van de Steeg, E.

    1. Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      Open Access
      Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      L. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de Steeg
      Drug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521

W

  1. Wang, Guangji

    1. Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Ran Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan Xie
      Drug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438

  2. Wang, Jinhai

    1. Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Open Access
      Role of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the Immunoproteasome
      Ying Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai Wang
      Drug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307

  3. Wang, Rui

    1. Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Ran Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan Xie
      Drug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438

  4. Wenzel, Christoph

    1. Comparative Hepatic and Intestinal Efflux Transport of Statins
      Open Access
      Comparative Hepatic and Intestinal Efflux Transport of Statins
      Feng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko Niemi
      Drug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430

X

  1. Xia, Menghang

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

  2. Xie, Yuan

    1. Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Ran Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan Xie
      Drug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438

  3. Xu, Dan

    1. Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Ran Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan Xie
      Drug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438

  4. Xu, Xin

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

Y

  1. Yamazaki, Hiroshi

    1. Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans
      Shiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki Nakajima
      Drug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513

  2. Yang, Na

    1. Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Ran Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan Xie
      Drug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438

  3. Yang, Qian

    1. Messenger RNA Expression of Albumin, Transferrin, Transthyretin, Asialoglycoprotein Receptor, Cytochrome P450 Isoform, Uptake Transporter, and Efflux Transporter Genes as a Function of Culture Duration in Prolonged Cultured Cryopreserved Human Hepatocytes as Collagen-Matrigel Sandwich Cultures: Evidence for Redifferentiation upon Prolonged Culturing
      Qian Yang and Albert P. Li
      Drug Metabolism and Disposition September 2021, 49 (9) 790-802; DOI: https://doi.org/10.1124/dmd.121.000424

Z

  1. Zakharov, Alexey

    1. Open Access
      Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition
      Eric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin Xu
      Drug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320

  2. Zhang, Ran

    1. Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Ran Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan Xie
      Drug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438

  3. Zhang, Yirui

    1. Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Ran Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan Xie
      Drug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438

  4. Zhang, Yongjie

    1. Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans
      Shiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki Nakajima
      Drug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513

  5. Zhao, Haokai

    1. Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease
      Ran Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan Xie
      Drug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438

  6. Zhu, A. Z. X.

    1. Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      Open Access
      Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
      L. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de Steeg
      Drug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521

  7. Zhu, Qiunan

    1. MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/<em>SLCO2B1</em> in Caco-2 Cells
      MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 Cells
      Hisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi Tamai
      Drug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380

  8. Zientek, Michael A.

    1. Open Access
      Contribution of Extrahepatic Aldehyde Oxidase Activity to Human Clearance
      Kirk D. Kozminski, Jangir Selimkhanov, Scott Heyward and Michael A. Zientek
      Drug Metabolism and Disposition September 2021, 49 (9) 743-749; DOI: https://doi.org/10.1124/dmd.120.000313
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