Index by author
September 01, 2021; Volume 49,Issue 9
A
Aa, Jiye
- You have accessSilybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver DiseaseRan Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan XieDrug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438
Alwayn, I. P. J.
- Open AccessEvaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using StatinsL. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de SteegDrug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521
Anderl, Janet L.
- Open AccessRole of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the ImmunoproteasomeYing Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai WangDrug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307
Andriopoulou, Christina E.
- You have accessOleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor αFoteini Malliou, Christina E. Andriopoulou, Frank J. Gonzalez, Aristeidis Kofinas, Alexios-Leandros Skaltsounis and Maria KonstandiDrug Metabolism and Disposition September 2021, 49 (9) 833-843; DOI: https://doi.org/10.1124/dmd.120.000302
B
Badee, Justine
- You have accessCharacterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 EnzymesRyan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen FowlerDrug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474
C
Carreño, Fernando O.
- You have accessLeveraging Physiologically Based Pharmacokinetic Modeling and Experimental Data to Guide Dosing Modification of CYP3A-Mediated Drug-Drug Interactions in the Pediatric PopulationSara N. Salerno, Fernando O. Carreño, Andrea N. Edginton, Michael Cohen-Wolkowiez and Daniel GonzalezDrug Metabolism and Disposition September 2021, 49 (9) 844-855; DOI: https://doi.org/10.1124/dmd.120.000318
Chan, Eric Chun Yong
- You have accessInfigratinib Is a Reversible Inhibitor and Mechanism-Based Inactivator of Cytochrome P450 3A4Lloyd Wei Tat Tang, Jian Wei Teng, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Mei Lin Go, Hao Fan and Eric Chun Yong ChanDrug Metabolism and Disposition September 2021, 49 (9) 856-868; DOI: https://doi.org/10.1124/dmd.121.000508
Chothe, P. P.
- Open AccessEvaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using StatinsL. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de SteegDrug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521
Chowdhury, S. K.
- Open AccessEvaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using StatinsL. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de SteegDrug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521
Cohen-Wolkowiez, Michael
- You have accessLeveraging Physiologically Based Pharmacokinetic Modeling and Experimental Data to Guide Dosing Modification of CYP3A-Mediated Drug-Drug Interactions in the Pediatric PopulationSara N. Salerno, Fernando O. Carreño, Andrea N. Edginton, Michael Cohen-Wolkowiez and Daniel GonzalezDrug Metabolism and Disposition September 2021, 49 (9) 844-855; DOI: https://doi.org/10.1124/dmd.120.000318
Collier, Abby C.
- You have accessCharacterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 EnzymesRyan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen FowlerDrug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474
D
Deng, Feng
- Open AccessComparative Hepatic and Intestinal Efflux Transport of StatinsFeng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko NiemiDrug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430
Donkers, J. M.
- Open AccessEvaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using StatinsL. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de SteegDrug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521
E
Edginton, Andrea N.
- You have accessLeveraging Physiologically Based Pharmacokinetic Modeling and Experimental Data to Guide Dosing Modification of CYP3A-Mediated Drug-Drug Interactions in the Pediatric PopulationSara N. Salerno, Fernando O. Carreño, Andrea N. Edginton, Michael Cohen-Wolkowiez and Daniel GonzalezDrug Metabolism and Disposition September 2021, 49 (9) 844-855; DOI: https://doi.org/10.1124/dmd.120.000318
F
Fan, Hao
- You have accessInfigratinib Is a Reversible Inhibitor and Mechanism-Based Inactivator of Cytochrome P450 3A4Lloyd Wei Tat Tang, Jian Wei Teng, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Mei Lin Go, Hao Fan and Eric Chun Yong ChanDrug Metabolism and Disposition September 2021, 49 (9) 856-868; DOI: https://doi.org/10.1124/dmd.121.000508
Fang, Ying
- Open AccessRole of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the ImmunoproteasomeYing Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai WangDrug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307
Filppula, Anne M.
- Open AccessComparative Hepatic and Intestinal Efflux Transport of StatinsFeng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko NiemiDrug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430
Forrest, William F.
- You have accessCharacterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 EnzymesRyan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen FowlerDrug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474
Fowler, Stephen
- You have accessCharacterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 EnzymesRyan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen FowlerDrug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474
Fujita, Daichi
- You have accessMicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 CellsHisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi TamaiDrug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380
Fukami, Tatsuki
- You have accessDifferences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and HumansShiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki NakajimaDrug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513
G
Garrido, Claudia
- You have accessThe Inactivation of Human Aldehyde Oxidase 1 by Hydrogen Peroxide and SuperoxideClaudia Garrido and Silke LeimkühlerDrug Metabolism and Disposition September 2021, 49 (9) 729-735; DOI: https://doi.org/10.1124/dmd.121.000549
Go, Mei Lin
- You have accessInfigratinib Is a Reversible Inhibitor and Mechanism-Based Inactivator of Cytochrome P450 3A4Lloyd Wei Tat Tang, Jian Wei Teng, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Mei Lin Go, Hao Fan and Eric Chun Yong ChanDrug Metabolism and Disposition September 2021, 49 (9) 856-868; DOI: https://doi.org/10.1124/dmd.121.000508
Gonzalez, Daniel
- You have accessLeveraging Physiologically Based Pharmacokinetic Modeling and Experimental Data to Guide Dosing Modification of CYP3A-Mediated Drug-Drug Interactions in the Pediatric PopulationSara N. Salerno, Fernando O. Carreño, Andrea N. Edginton, Michael Cohen-Wolkowiez and Daniel GonzalezDrug Metabolism and Disposition September 2021, 49 (9) 844-855; DOI: https://doi.org/10.1124/dmd.120.000318
Gonzalez, Eric
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
Gonzalez, Frank J.
- You have accessOleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor αFoteini Malliou, Christina E. Andriopoulou, Frank J. Gonzalez, Aristeidis Kofinas, Alexios-Leandros Skaltsounis and Maria KonstandiDrug Metabolism and Disposition September 2021, 49 (9) 833-843; DOI: https://doi.org/10.1124/dmd.120.000302
H
Hammock, Bruce D.
- Open AccessRole of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the ImmunoproteasomeYing Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai WangDrug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307
Heyward, Scott
- Open AccessContribution of Extrahepatic Aldehyde Oxidase Activity to Human ClearanceKirk D. Kozminski, Jangir Selimkhanov, Scott Heyward and Michael A. ZientekDrug Metabolism and Disposition September 2021, 49 (9) 743-749; DOI: https://doi.org/10.1124/dmd.120.000313
Hirosawa, Keiya
- You have accessDifferences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and HumansShiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki NakajimaDrug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513
Hirvensalo, Päivi
- Open AccessComparative Hepatic and Intestinal Efflux Transport of StatinsFeng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko NiemiDrug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430
Honda, Shiori
- You have accessDifferences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and HumansShiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki NakajimaDrug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513
Hop, Cornelis E. C. A.
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
Huang, Ruili
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
I
Iwamoto, Yui
- You have accessMicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 CellsHisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi TamaiDrug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380
J
Jain, Sankalp
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
Johnson, Henry
- Open AccessRole of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the ImmunoproteasomeYing Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai WangDrug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307
Jones, Barry
- You have accessImpact of Interindividual Differences in Plasma Fraction Unbound on the Pharmacokinetics of a Novel Syk Kinase Inhibitor in Beagle DogsAndy Pike, Barry Jones, Roshini Markandu and Daniel O’NeillDrug Metabolism and Disposition September 2021, 49 (9) 736-742; DOI: https://doi.org/10.1124/dmd.121.000409
K
Kirk, Christopher
- Open AccessRole of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the ImmunoproteasomeYing Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai WangDrug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307
Knibbe, C. A. J.
- Open AccessEvaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using StatinsL. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de SteegDrug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521
Kofinas, Aristeidis
- You have accessOleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor αFoteini Malliou, Christina E. Andriopoulou, Frank J. Gonzalez, Aristeidis Kofinas, Alexios-Leandros Skaltsounis and Maria KonstandiDrug Metabolism and Disposition September 2021, 49 (9) 833-843; DOI: https://doi.org/10.1124/dmd.120.000302
Koh, Siew Kwan
- You have accessInfigratinib Is a Reversible Inhibitor and Mechanism-Based Inactivator of Cytochrome P450 3A4Lloyd Wei Tat Tang, Jian Wei Teng, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Mei Lin Go, Hao Fan and Eric Chun Yong ChanDrug Metabolism and Disposition September 2021, 49 (9) 856-868; DOI: https://doi.org/10.1124/dmd.121.000508
Komori, Hisakazu
- You have accessMicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 CellsHisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi TamaiDrug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380
Konstandi, Maria
- You have accessOleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor αFoteini Malliou, Christina E. Andriopoulou, Frank J. Gonzalez, Aristeidis Kofinas, Alexios-Leandros Skaltsounis and Maria KonstandiDrug Metabolism and Disposition September 2021, 49 (9) 833-843; DOI: https://doi.org/10.1124/dmd.120.000302
Kozminski, Kirk D.
- Open AccessContribution of Extrahepatic Aldehyde Oxidase Activity to Human ClearanceKirk D. Kozminski, Jangir Selimkhanov, Scott Heyward and Michael A. ZientekDrug Metabolism and Disposition September 2021, 49 (9) 743-749; DOI: https://doi.org/10.1124/dmd.120.000313
Kulju, Sami
- Open AccessComparative Hepatic and Intestinal Efflux Transport of StatinsFeng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko NiemiDrug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430
L
Leimkühler, Silke
- You have accessThe Inactivation of Human Aldehyde Oxidase 1 by Hydrogen Peroxide and SuperoxideClaudia Garrido and Silke LeimkühlerDrug Metabolism and Disposition September 2021, 49 (9) 729-735; DOI: https://doi.org/10.1124/dmd.121.000549
Li, Albert P.
- You have accessMessenger RNA Expression of Albumin, Transferrin, Transthyretin, Asialoglycoprotein Receptor, Cytochrome P450 Isoform, Uptake Transporter, and Efflux Transporter Genes as a Function of Culture Duration in Prolonged Cultured Cryopreserved Human Hepatocytes as Collagen-Matrigel Sandwich Cultures: Evidence for Redifferentiation upon Prolonged CulturingQian Yang and Albert P. LiDrug Metabolism and Disposition September 2021, 49 (9) 790-802; DOI: https://doi.org/10.1124/dmd.121.000424
Lou, Yunge
- You have accessSilybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver DiseaseRan Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan XieDrug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438
M
Malliou, Foteini
- You have accessOleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor αFoteini Malliou, Christina E. Andriopoulou, Frank J. Gonzalez, Aristeidis Kofinas, Alexios-Leandros Skaltsounis and Maria KonstandiDrug Metabolism and Disposition September 2021, 49 (9) 833-843; DOI: https://doi.org/10.1124/dmd.120.000302
Markandu, Roshini
- You have accessImpact of Interindividual Differences in Plasma Fraction Unbound on the Pharmacokinetics of a Novel Syk Kinase Inhibitor in Beagle DogsAndy Pike, Barry Jones, Roshini Markandu and Daniel O’NeillDrug Metabolism and Disposition September 2021, 49 (9) 736-742; DOI: https://doi.org/10.1124/dmd.121.000409
McMinn, Dustin
- Open AccessRole of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the ImmunoproteasomeYing Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai WangDrug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307
Morisseau, Christophe
- Open AccessRole of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the ImmunoproteasomeYing Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai WangDrug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307
Muchamuel, Tony
- Open AccessRole of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the ImmunoproteasomeYing Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai WangDrug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307
N
Nakajima, Miki
- You have accessDifferences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and HumansShiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki NakajimaDrug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513
- You have accessMicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 CellsHisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi TamaiDrug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380
Nakanishi, Takeo
- You have accessMicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 CellsHisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi TamaiDrug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380
Nakano, Masataka
- You have accessDifferences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and HumansShiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki NakajimaDrug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513
Neuvonen, Mikko
- Open AccessComparative Hepatic and Intestinal Efflux Transport of StatinsFeng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko NiemiDrug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430
Nguyễn, Ðắc-Trung
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
Niemi, Mikko
- Open AccessComparative Hepatic and Intestinal Efflux Transport of StatinsFeng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko NiemiDrug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430
O
O’Neill, Daniel
- You have accessImpact of Interindividual Differences in Plasma Fraction Unbound on the Pharmacokinetics of a Novel Syk Kinase Inhibitor in Beagle DogsAndy Pike, Barry Jones, Roshini Markandu and Daniel O’NeillDrug Metabolism and Disposition September 2021, 49 (9) 736-742; DOI: https://doi.org/10.1124/dmd.121.000409
Obach, R. Scott
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
Oswald, Stefan
- Open AccessComparative Hepatic and Intestinal Efflux Transport of StatinsFeng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko NiemiDrug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430
P
Parrott, Neil
- You have accessCharacterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 EnzymesRyan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen FowlerDrug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474
Pike, Andy
- You have accessImpact of Interindividual Differences in Plasma Fraction Unbound on the Pharmacokinetics of a Novel Syk Kinase Inhibitor in Beagle DogsAndy Pike, Barry Jones, Roshini Markandu and Daniel O’NeillDrug Metabolism and Disposition September 2021, 49 (9) 736-742; DOI: https://doi.org/10.1124/dmd.121.000409
Q
Qiu, NaHong
- You have accessCharacterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 EnzymesRyan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen FowlerDrug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474
S
Sakamuru, Srilatha
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
Salerno, Sara N.
- You have accessLeveraging Physiologically Based Pharmacokinetic Modeling and Experimental Data to Guide Dosing Modification of CYP3A-Mediated Drug-Drug Interactions in the Pediatric PopulationSara N. Salerno, Fernando O. Carreño, Andrea N. Edginton, Michael Cohen-Wolkowiez and Daniel GonzalezDrug Metabolism and Disposition September 2021, 49 (9) 844-855; DOI: https://doi.org/10.1124/dmd.120.000318
Schmidt, Stephan
- You have accessCharacterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 EnzymesRyan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen FowlerDrug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474
Selimkhanov, Jangir
- Open AccessContribution of Extrahepatic Aldehyde Oxidase Activity to Human ClearanceKirk D. Kozminski, Jangir Selimkhanov, Scott Heyward and Michael A. ZientekDrug Metabolism and Disposition September 2021, 49 (9) 743-749; DOI: https://doi.org/10.1124/dmd.120.000313
Shah, Pranav
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
Shirasaki, Yuma
- You have accessMicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 CellsHisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi TamaiDrug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380
Simeonov, Anton
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
Skaltsounis, Alexios-Leandros
- You have accessOleuropein-Induced Acceleration of Cytochrome P450–Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor αFoteini Malliou, Christina E. Andriopoulou, Frank J. Gonzalez, Aristeidis Kofinas, Alexios-Leandros Skaltsounis and Maria KonstandiDrug Metabolism and Disposition September 2021, 49 (9) 833-843; DOI: https://doi.org/10.1124/dmd.120.000302
Smith, Alexander D.
- You have accessCharacterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 EnzymesRyan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen FowlerDrug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474
Stevens, L. J.
- Open AccessEvaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using StatinsL. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de SteegDrug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521
T
Takahashi, Ryan H.
- You have accessCharacterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 EnzymesRyan H. Takahashi, William F. Forrest, Alexander D. Smith, Justine Badee, NaHong Qiu, Stephan Schmidt, Abby C. Collier, Neil Parrott and Stephen FowlerDrug Metabolism and Disposition September 2021, 49 (9) 760-769; DOI: https://doi.org/10.1124/dmd.121.000474
Tamai, Ikumi
- You have accessMicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 CellsHisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi TamaiDrug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380
Tang, Lloyd Wei Tat
- You have accessInfigratinib Is a Reversible Inhibitor and Mechanism-Based Inactivator of Cytochrome P450 3A4Lloyd Wei Tat Tang, Jian Wei Teng, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Mei Lin Go, Hao Fan and Eric Chun Yong ChanDrug Metabolism and Disposition September 2021, 49 (9) 856-868; DOI: https://doi.org/10.1124/dmd.121.000508
Teng, Jian Wei
- You have accessInfigratinib Is a Reversible Inhibitor and Mechanism-Based Inactivator of Cytochrome P450 3A4Lloyd Wei Tat Tang, Jian Wei Teng, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Mei Lin Go, Hao Fan and Eric Chun Yong ChanDrug Metabolism and Disposition September 2021, 49 (9) 856-868; DOI: https://doi.org/10.1124/dmd.121.000508
Torimoto-Katori, Nao
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
Tsujiguchi, Takuya
- You have accessDifferences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and HumansShiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki NakajimaDrug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513
Tuomi, Suvi-Kukka
- Open AccessComparative Hepatic and Intestinal Efflux Transport of StatinsFeng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko NiemiDrug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430
U
Uehara, Shotaro
- You have accessDifferences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and HumansShiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki NakajimaDrug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513
Uno, Yasuhiro
- You have accessDifferences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and HumansShiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki NakajimaDrug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513
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Vaes, W. H. J.
- Open AccessEvaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using StatinsL. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de SteegDrug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521
van de Steeg, E.
- Open AccessEvaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using StatinsL. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de SteegDrug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521
Verma, Ravi Kumar
- You have accessInfigratinib Is a Reversible Inhibitor and Mechanism-Based Inactivator of Cytochrome P450 3A4Lloyd Wei Tat Tang, Jian Wei Teng, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Mei Lin Go, Hao Fan and Eric Chun Yong ChanDrug Metabolism and Disposition September 2021, 49 (9) 856-868; DOI: https://doi.org/10.1124/dmd.121.000508
W
Wang, Guangji
- You have accessSilybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver DiseaseRan Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan XieDrug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438
Wang, Jinhai
- Open AccessRole of Epoxide Hydrolases and Cytochrome P450s on Metabolism of KZR-616, a First-in-Class Selective Inhibitor of the ImmunoproteasomeYing Fang, Henry Johnson, Janet L. Anderl, Tony Muchamuel, Dustin McMinn, Christophe Morisseau, Bruce D. Hammock, Christopher Kirk and Jinhai WangDrug Metabolism and Disposition September 2021, 49 (9) 810-821; DOI: https://doi.org/10.1124/dmd.120.000307
Wang, Rui
- You have accessSilybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver DiseaseRan Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan XieDrug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438
Wenzel, Christoph
- Open AccessComparative Hepatic and Intestinal Efflux Transport of StatinsFeng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko NiemiDrug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430
X
Xia, Menghang
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
Xie, Yuan
- You have accessSilybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver DiseaseRan Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan XieDrug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438
Xu, Dan
- You have accessSilybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver DiseaseRan Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan XieDrug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438
Xu, Xin
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
Y
Yamazaki, Hiroshi
- You have accessDifferences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and HumansShiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki NakajimaDrug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513
Yang, Na
- You have accessSilybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver DiseaseRan Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan XieDrug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438
Yang, Qian
- You have accessMessenger RNA Expression of Albumin, Transferrin, Transthyretin, Asialoglycoprotein Receptor, Cytochrome P450 Isoform, Uptake Transporter, and Efflux Transporter Genes as a Function of Culture Duration in Prolonged Cultured Cryopreserved Human Hepatocytes as Collagen-Matrigel Sandwich Cultures: Evidence for Redifferentiation upon Prolonged CulturingQian Yang and Albert P. LiDrug Metabolism and Disposition September 2021, 49 (9) 790-802; DOI: https://doi.org/10.1124/dmd.121.000424
Z
Zakharov, Alexey
- Open AccessDevelopment of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and InhibitionEric Gonzalez, Sankalp Jain, Pranav Shah, Nao Torimoto-Katori, Alexey Zakharov, Ðắc-Trung Nguyễn, Srilatha Sakamuru, Ruili Huang, Menghang Xia, R. Scott Obach, Cornelis E. C. A. Hop, Anton Simeonov and Xin XuDrug Metabolism and Disposition September 2021, 49 (9) 822-832; DOI: https://doi.org/10.1124/dmd.120.000320
Zhang, Ran
- You have accessSilybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver DiseaseRan Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan XieDrug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438
Zhang, Yirui
- You have accessSilybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver DiseaseRan Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan XieDrug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438
Zhang, Yongjie
- You have accessDifferences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and HumansShiori Honda, Tatsuki Fukami, Keiya Hirosawa, Takuya Tsujiguchi, Yongjie Zhang, Masataka Nakano, Shotaro Uehara, Yasuhiro Uno, Hiroshi Yamazaki and Miki NakajimaDrug Metabolism and Disposition September 2021, 49 (9) 718-728; DOI: https://doi.org/10.1124/dmd.121.000513
Zhao, Haokai
- You have accessSilybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver DiseaseRan Zhang, Dan Xu, Yirui Zhang, Rui Wang, Na Yang, Yunge Lou, Haokai Zhao, Jiye Aa, Guangji Wang and Yuan XieDrug Metabolism and Disposition September 2021, 49 (9) 770-779; DOI: https://doi.org/10.1124/dmd.121.000438
Zhou, Lei
- You have accessInfigratinib Is a Reversible Inhibitor and Mechanism-Based Inactivator of Cytochrome P450 3A4Lloyd Wei Tat Tang, Jian Wei Teng, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Mei Lin Go, Hao Fan and Eric Chun Yong ChanDrug Metabolism and Disposition September 2021, 49 (9) 856-868; DOI: https://doi.org/10.1124/dmd.121.000508
Zhu, A. Z. X.
- Open AccessEvaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using StatinsL. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de SteegDrug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521
Zhu, Qiunan
- You have accessMicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 CellsHisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi TamaiDrug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380
Zientek, Michael A.
- Open AccessContribution of Extrahepatic Aldehyde Oxidase Activity to Human ClearanceKirk D. Kozminski, Jangir Selimkhanov, Scott Heyward and Michael A. ZientekDrug Metabolism and Disposition September 2021, 49 (9) 743-749; DOI: https://doi.org/10.1124/dmd.120.000313
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