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Research ArticleArticle

MicroRNAs in Apple-Derived Nanoparticles Modulate Intestinal Expression of Organic Anion–Transporting Peptide 2B1/SLCO2B1 in Caco-2 Cells

Hisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi Tamai
Drug Metabolism and Disposition September 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380
Hisakazu Komori
Department of Membrane Transport and Biopharmaceutics (H.K., D.F., Y.S., Q.Z., Y.I., T.N., I.T.), Department of Drug Metabolism and Toxicology (M.N.), Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, and WPI Nano Life Science Institute (M.N.), Kanazawa University, Kakuma-machi, Kanazawa, Japan
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Daichi Fujita
Department of Membrane Transport and Biopharmaceutics (H.K., D.F., Y.S., Q.Z., Y.I., T.N., I.T.), Department of Drug Metabolism and Toxicology (M.N.), Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, and WPI Nano Life Science Institute (M.N.), Kanazawa University, Kakuma-machi, Kanazawa, Japan
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Yuma Shirasaki
Department of Membrane Transport and Biopharmaceutics (H.K., D.F., Y.S., Q.Z., Y.I., T.N., I.T.), Department of Drug Metabolism and Toxicology (M.N.), Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, and WPI Nano Life Science Institute (M.N.), Kanazawa University, Kakuma-machi, Kanazawa, Japan
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Qiunan Zhu
Department of Membrane Transport and Biopharmaceutics (H.K., D.F., Y.S., Q.Z., Y.I., T.N., I.T.), Department of Drug Metabolism and Toxicology (M.N.), Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, and WPI Nano Life Science Institute (M.N.), Kanazawa University, Kakuma-machi, Kanazawa, Japan
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Yui Iwamoto
Department of Membrane Transport and Biopharmaceutics (H.K., D.F., Y.S., Q.Z., Y.I., T.N., I.T.), Department of Drug Metabolism and Toxicology (M.N.), Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, and WPI Nano Life Science Institute (M.N.), Kanazawa University, Kakuma-machi, Kanazawa, Japan
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Takeo Nakanishi
Department of Membrane Transport and Biopharmaceutics (H.K., D.F., Y.S., Q.Z., Y.I., T.N., I.T.), Department of Drug Metabolism and Toxicology (M.N.), Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, and WPI Nano Life Science Institute (M.N.), Kanazawa University, Kakuma-machi, Kanazawa, Japan
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Miki Nakajima
Department of Membrane Transport and Biopharmaceutics (H.K., D.F., Y.S., Q.Z., Y.I., T.N., I.T.), Department of Drug Metabolism and Toxicology (M.N.), Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, and WPI Nano Life Science Institute (M.N.), Kanazawa University, Kakuma-machi, Kanazawa, Japan
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Ikumi Tamai
Department of Membrane Transport and Biopharmaceutics (H.K., D.F., Y.S., Q.Z., Y.I., T.N., I.T.), Department of Drug Metabolism and Toxicology (M.N.), Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, and WPI Nano Life Science Institute (M.N.), Kanazawa University, Kakuma-machi, Kanazawa, Japan
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Drug Metabolism and Disposition: 49 (9)
Drug Metabolism and Disposition
Vol. 49, Issue 9
1 Sep 2021
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Research ArticleArticle

Regulation of OATP2B1 by Apple miRNA in Nanoparticles

Hisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi Tamai
Drug Metabolism and Disposition September 1, 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380

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Research ArticleArticle

Regulation of OATP2B1 by Apple miRNA in Nanoparticles

Hisakazu Komori, Daichi Fujita, Yuma Shirasaki, Qiunan Zhu, Yui Iwamoto, Takeo Nakanishi, Miki Nakajima and Ikumi Tamai
Drug Metabolism and Disposition September 1, 2021, 49 (9) 803-809; DOI: https://doi.org/10.1124/dmd.121.000380
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