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Drug Metabolism & Disposition

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Table of Contents

July 01, 1977; Volume 5,Issue 4
  • You have access
    Metabolism and disposition of l-alpha-acetylmethadol in the rat.
    G L Henderson, H North-Root and S H Kuttab
    Drug Metabolism and Disposition July 1977, 5 (4) 321-328;
  • You have access
    The metabolism of p-methoxyamphetamine in dog and monkey. O-demethylation as a major route.
    J W Hubbard, K K Midha and J K Cooper
    Drug Metabolism and Disposition July 1977, 5 (4) 329-334;
  • You have access
    Biotransformation of morphine to dihydromorphinone and normorphine in the mouse, rat, rabbit, guinea pig, cat, dog, and monkey.
    S Y Yeh, R L McQuinn and C W Gorodetzky
    Drug Metabolism and Disposition July 1977, 5 (4) 335-342;
  • You have access
    Determination of optically active thiopental, thiamylal, and their metabolites in human urine.
    F I Carroll, D Smith, L C Mark, L Brand and J M Perel
    Drug Metabolism and Disposition July 1977, 5 (4) 343-354;
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    The interrelationship between the metabolism of (S)-continine-N-oxide and (S)-cotinine.
    J M Yi, C T Sprouse, E R Bowman and H McKennis
    Drug Metabolism and Disposition July 1977, 5 (4) 355-362;
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    The metabolism of styrene oxide in the isolated perfused rat liver. Identification and quantitation of major metabolites.
    A J Ryan and J R Bend
    Drug Metabolism and Disposition July 1977, 5 (4) 363-367;
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    Biliary excretion of iopanoate glucuronide by the rat.
    W J Cooke and L Cooke
    Drug Metabolism and Disposition July 1977, 5 (4) 368-376;
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    Effects of anesthetic agents on the biliary excretion of iopanoate in the rat.
    W J Cooke and L Cooke
    Drug Metabolism and Disposition July 1977, 5 (4) 377-385;
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    A preliminary pharmacokinetic model for several chlorinated biphenyls in the rat.
    R J Lutz, R L Dedrick, H B Matthews, T E Eling and M W Anderson
    Drug Metabolism and Disposition July 1977, 5 (4) 386-396;
  • You have access
    Studies on the glucuronidation of 7-hydroxychlorpromazine in vitro.
    J V Dingell and N Sossi
    Drug Metabolism and Disposition July 1977, 5 (4) 397-404;
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    Effect of experimental diabetes on drug metabolism in the rat.
    D M Ackerman and K C Leibman
    Drug Metabolism and Disposition July 1977, 5 (4) 405-410;
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    Novel routes of drug metabolism. A survey.
    Z H Israili, P G Dayton and J R Kiechel
    Drug Metabolism and Disposition July 1977, 5 (4) 411-415;
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In this issue

Drug Metabolism and Disposition
Vol. 5, Issue 4
1 Jul 1977
  • Table of Contents
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
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