Index by author
January 01, 2022; Volume 50,Issue 1
B
Barbier, Olivier
- You have accessIntestinal UDP-Glucuronosyltransferase 1A1 and Protection against Irinotecan-Induced Toxicity in a Novel UDP-Glucuronosyltransferase 1A1 Tissue-Specific Humanized Mouse ModelElvira Mennillo, Xiaojing Yang, Andre A. Weber, Yoshihiro Maruo, Melanie Verreault, Olivier Barbier, Shujuan Chen and Robert H. TukeyDrug Metabolism and Disposition January 2022, 50 (1) 33-42; DOI: https://doi.org/10.1124/dmd.121.000644
Bart, Aaron G.
- You have accessCytochrome P450 Binding and Bioactivation of Tumor-Targeted Duocarmycin AgentsAaron G. Bart, Goreti Morais, Venu R. Vangala, Paul M. Loadman, Klaus Pors and Emily E. ScottDrug Metabolism and Disposition January 2022, 50 (1) 49-57; DOI: https://doi.org/10.1124/dmd.121.000642
Brink, Andreas
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
Brouwer, Kim L.R.
- You have accessNew Pharmacokinetic Parameters of Imaging Substrates Quantified from Rat Liver CompartmentsCatherine M. Pastor and Kim L.R. BrouwerDrug Metabolism and Disposition January 2022, 50 (1) 58-64; DOI: https://doi.org/10.1124/dmd.121.000546
C
Chen, Shujuan
- You have accessIntestinal UDP-Glucuronosyltransferase 1A1 and Protection against Irinotecan-Induced Toxicity in a Novel UDP-Glucuronosyltransferase 1A1 Tissue-Specific Humanized Mouse ModelElvira Mennillo, Xiaojing Yang, Andre A. Weber, Yoshihiro Maruo, Melanie Verreault, Olivier Barbier, Shujuan Chen and Robert H. TukeyDrug Metabolism and Disposition January 2022, 50 (1) 33-42; DOI: https://doi.org/10.1124/dmd.121.000644
Cleary, Yumi
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
Collins, Joseph M.
- You have accessTranscriptional Regulation of Carboxylesterase 1 in Human Liver: Role of the Nuclear Receptor Subfamily 1 Group H Member 3 and Its Splice IsoformsJoseph M. Collins, Rong Lu, Xinwen Wang, Hao-Jie Zhu and Danxin WangDrug Metabolism and Disposition January 2022, 50 (1) 43-48; DOI: https://doi.org/10.1124/dmd.121.000649
D
Dinh, Jean C.
- You have accessOntogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of LiverJ. Steven Leeder, Jean C. Dinh, Andrea Gaedigk, Vincent S. Staggs, Bhagwat Prasad and Robin E. PearceDrug Metabolism and Disposition January 2022, 50 (1) 24-32; DOI: https://doi.org/10.1124/dmd.121.000623
F
Fowler, Stephen
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
G
Gaedigk, Andrea
- You have accessOntogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of LiverJ. Steven Leeder, Jean C. Dinh, Andrea Gaedigk, Vincent S. Staggs, Bhagwat Prasad and Robin E. PearceDrug Metabolism and Disposition January 2022, 50 (1) 24-32; DOI: https://doi.org/10.1124/dmd.121.000623
Günther, Andreas
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
H
Hanioka, Nobumitsu
- You have accessSimultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase–Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell–Derived Small Intestinal Epithelial CellsTakashi Kitaguchi, Taisei Mizota, Mina Ito, Katsutoshi Ohno, Kazuhiro Kobayashi, Isamu Ogawa, Shimeng Qiu, Takahiro Iwao, Nobumitsu Hanioka, Mitsuru Tanaka and Tamihide MatsunagaDrug Metabolism and Disposition January 2022, 50 (1) 17-23; DOI: https://doi.org/10.1124/dmd.121.000605
Heinig, Katja
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
Husser, Christophe
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
I
Ito, Mina
- You have accessSimultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase–Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell–Derived Small Intestinal Epithelial CellsTakashi Kitaguchi, Taisei Mizota, Mina Ito, Katsutoshi Ohno, Kazuhiro Kobayashi, Isamu Ogawa, Shimeng Qiu, Takahiro Iwao, Nobumitsu Hanioka, Mitsuru Tanaka and Tamihide MatsunagaDrug Metabolism and Disposition January 2022, 50 (1) 17-23; DOI: https://doi.org/10.1124/dmd.121.000605
Iwao, Takahiro
- You have accessSimultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase–Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell–Derived Small Intestinal Epithelial CellsTakashi Kitaguchi, Taisei Mizota, Mina Ito, Katsutoshi Ohno, Kazuhiro Kobayashi, Isamu Ogawa, Shimeng Qiu, Takahiro Iwao, Nobumitsu Hanioka, Mitsuru Tanaka and Tamihide MatsunagaDrug Metabolism and Disposition January 2022, 50 (1) 17-23; DOI: https://doi.org/10.1124/dmd.121.000605
K
Kitaguchi, Takashi
- You have accessSimultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase–Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell–Derived Small Intestinal Epithelial CellsTakashi Kitaguchi, Taisei Mizota, Mina Ito, Katsutoshi Ohno, Kazuhiro Kobayashi, Isamu Ogawa, Shimeng Qiu, Takahiro Iwao, Nobumitsu Hanioka, Mitsuru Tanaka and Tamihide MatsunagaDrug Metabolism and Disposition January 2022, 50 (1) 17-23; DOI: https://doi.org/10.1124/dmd.121.000605
Kletzl, Heidemarie
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
Kobayashi, Kazuhiro
- You have accessSimultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase–Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell–Derived Small Intestinal Epithelial CellsTakashi Kitaguchi, Taisei Mizota, Mina Ito, Katsutoshi Ohno, Kazuhiro Kobayashi, Isamu Ogawa, Shimeng Qiu, Takahiro Iwao, Nobumitsu Hanioka, Mitsuru Tanaka and Tamihide MatsunagaDrug Metabolism and Disposition January 2022, 50 (1) 17-23; DOI: https://doi.org/10.1124/dmd.121.000605
Kratochwil, Nicole
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
L
Lai, Yuen Sze
- You have accessOverview of Current Herb–Drug Interaction DatabasesYufeng Zhang, Chung Man Ip, Yuen Sze Lai and Zhong ZuoDrug Metabolism and Disposition January 2022, 50 (1) 86-94; DOI: https://doi.org/10.1124/dmd.121.000420
Leeder, J. Steven
- You have accessOntogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of LiverJ. Steven Leeder, Jean C. Dinh, Andrea Gaedigk, Vincent S. Staggs, Bhagwat Prasad and Robin E. PearceDrug Metabolism and Disposition January 2022, 50 (1) 24-32; DOI: https://doi.org/10.1124/dmd.121.000623
Li, Fengcheng
- You have accessFeature, Function, and Information of Drug Transporter–Related DatabasesJiayi Yin, Fengcheng Li, Zhaorong Li, Lushan Yu, Feng Zhu and Su ZengDrug Metabolism and Disposition January 2022, 50 (1) 76-85; DOI: https://doi.org/10.1124/dmd.121.000419
Li, Zhaorong
- You have accessFeature, Function, and Information of Drug Transporter–Related DatabasesJiayi Yin, Fengcheng Li, Zhaorong Li, Lushan Yu, Feng Zhu and Su ZengDrug Metabolism and Disposition January 2022, 50 (1) 76-85; DOI: https://doi.org/10.1124/dmd.121.000419
Linderman, Jennifer J.
- You have accessSimulating the Selection of Resistant Cells with Bystander Killing and Antibody Coadministration in Heterogeneous Human Epidermal Growth Factor Receptor 2–Positive TumorsBruna Menezes, Jennifer J. Linderman and Greg M. ThurberDrug Metabolism and Disposition January 2022, 50 (1) 8-16; DOI: https://doi.org/10.1124/dmd.121.000503
Loadman, Paul M.
- You have accessCytochrome P450 Binding and Bioactivation of Tumor-Targeted Duocarmycin AgentsAaron G. Bart, Goreti Morais, Venu R. Vangala, Paul M. Loadman, Klaus Pors and Emily E. ScottDrug Metabolism and Disposition January 2022, 50 (1) 49-57; DOI: https://doi.org/10.1124/dmd.121.000642
Lu, Rong
- You have accessTranscriptional Regulation of Carboxylesterase 1 in Human Liver: Role of the Nuclear Receptor Subfamily 1 Group H Member 3 and Its Splice IsoformsJoseph M. Collins, Rong Lu, Xinwen Wang, Hao-Jie Zhu and Danxin WangDrug Metabolism and Disposition January 2022, 50 (1) 43-48; DOI: https://doi.org/10.1124/dmd.121.000649
M
Man Ip, Chung
- You have accessOverview of Current Herb–Drug Interaction DatabasesYufeng Zhang, Chung Man Ip, Yuen Sze Lai and Zhong ZuoDrug Metabolism and Disposition January 2022, 50 (1) 86-94; DOI: https://doi.org/10.1124/dmd.121.000420
Maruo, Yoshihiro
- You have accessIntestinal UDP-Glucuronosyltransferase 1A1 and Protection against Irinotecan-Induced Toxicity in a Novel UDP-Glucuronosyltransferase 1A1 Tissue-Specific Humanized Mouse ModelElvira Mennillo, Xiaojing Yang, Andre A. Weber, Yoshihiro Maruo, Melanie Verreault, Olivier Barbier, Shujuan Chen and Robert H. TukeyDrug Metabolism and Disposition January 2022, 50 (1) 33-42; DOI: https://doi.org/10.1124/dmd.121.000644
Matsunaga, Tamihide
- You have accessSimultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase–Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell–Derived Small Intestinal Epithelial CellsTakashi Kitaguchi, Taisei Mizota, Mina Ito, Katsutoshi Ohno, Kazuhiro Kobayashi, Isamu Ogawa, Shimeng Qiu, Takahiro Iwao, Nobumitsu Hanioka, Mitsuru Tanaka and Tamihide MatsunagaDrug Metabolism and Disposition January 2022, 50 (1) 17-23; DOI: https://doi.org/10.1124/dmd.121.000605
Menezes, Bruna
- You have accessSimulating the Selection of Resistant Cells with Bystander Killing and Antibody Coadministration in Heterogeneous Human Epidermal Growth Factor Receptor 2–Positive TumorsBruna Menezes, Jennifer J. Linderman and Greg M. ThurberDrug Metabolism and Disposition January 2022, 50 (1) 8-16; DOI: https://doi.org/10.1124/dmd.121.000503
Mennillo, Elvira
- You have accessIntestinal UDP-Glucuronosyltransferase 1A1 and Protection against Irinotecan-Induced Toxicity in a Novel UDP-Glucuronosyltransferase 1A1 Tissue-Specific Humanized Mouse ModelElvira Mennillo, Xiaojing Yang, Andre A. Weber, Yoshihiro Maruo, Melanie Verreault, Olivier Barbier, Shujuan Chen and Robert H. TukeyDrug Metabolism and Disposition January 2022, 50 (1) 33-42; DOI: https://doi.org/10.1124/dmd.121.000644
Mizota, Taisei
- You have accessSimultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase–Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell–Derived Small Intestinal Epithelial CellsTakashi Kitaguchi, Taisei Mizota, Mina Ito, Katsutoshi Ohno, Kazuhiro Kobayashi, Isamu Ogawa, Shimeng Qiu, Takahiro Iwao, Nobumitsu Hanioka, Mitsuru Tanaka and Tamihide MatsunagaDrug Metabolism and Disposition January 2022, 50 (1) 17-23; DOI: https://doi.org/10.1124/dmd.121.000605
Morais, Goreti
- You have accessCytochrome P450 Binding and Bioactivation of Tumor-Targeted Duocarmycin AgentsAaron G. Bart, Goreti Morais, Venu R. Vangala, Paul M. Loadman, Klaus Pors and Emily E. ScottDrug Metabolism and Disposition January 2022, 50 (1) 49-57; DOI: https://doi.org/10.1124/dmd.121.000642
Mueller, Lutz
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
O
Ogawa, Isamu
- You have accessSimultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase–Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell–Derived Small Intestinal Epithelial CellsTakashi Kitaguchi, Taisei Mizota, Mina Ito, Katsutoshi Ohno, Kazuhiro Kobayashi, Isamu Ogawa, Shimeng Qiu, Takahiro Iwao, Nobumitsu Hanioka, Mitsuru Tanaka and Tamihide MatsunagaDrug Metabolism and Disposition January 2022, 50 (1) 17-23; DOI: https://doi.org/10.1124/dmd.121.000605
Ohno, Katsutoshi
- You have accessSimultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase–Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell–Derived Small Intestinal Epithelial CellsTakashi Kitaguchi, Taisei Mizota, Mina Ito, Katsutoshi Ohno, Kazuhiro Kobayashi, Isamu Ogawa, Shimeng Qiu, Takahiro Iwao, Nobumitsu Hanioka, Mitsuru Tanaka and Tamihide MatsunagaDrug Metabolism and Disposition January 2022, 50 (1) 17-23; DOI: https://doi.org/10.1124/dmd.121.000605
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Pastor, Catherine M.
- You have accessNew Pharmacokinetic Parameters of Imaging Substrates Quantified from Rat Liver CompartmentsCatherine M. Pastor and Kim L.R. BrouwerDrug Metabolism and Disposition January 2022, 50 (1) 58-64; DOI: https://doi.org/10.1124/dmd.121.000546
Pearce, Robin E.
- You have accessOntogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of LiverJ. Steven Leeder, Jean C. Dinh, Andrea Gaedigk, Vincent S. Staggs, Bhagwat Prasad and Robin E. PearceDrug Metabolism and Disposition January 2022, 50 (1) 24-32; DOI: https://doi.org/10.1124/dmd.121.000623
Poirier, Agnès
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
Pors, Klaus
- You have accessCytochrome P450 Binding and Bioactivation of Tumor-Targeted Duocarmycin AgentsAaron G. Bart, Goreti Morais, Venu R. Vangala, Paul M. Loadman, Klaus Pors and Emily E. ScottDrug Metabolism and Disposition January 2022, 50 (1) 49-57; DOI: https://doi.org/10.1124/dmd.121.000642
Prasad, Bhagwat
- You have accessOntogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of LiverJ. Steven Leeder, Jean C. Dinh, Andrea Gaedigk, Vincent S. Staggs, Bhagwat Prasad and Robin E. PearceDrug Metabolism and Disposition January 2022, 50 (1) 24-32; DOI: https://doi.org/10.1124/dmd.121.000623
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Qiu, Shimeng
- You have accessSimultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase–Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell–Derived Small Intestinal Epithelial CellsTakashi Kitaguchi, Taisei Mizota, Mina Ito, Katsutoshi Ohno, Kazuhiro Kobayashi, Isamu Ogawa, Shimeng Qiu, Takahiro Iwao, Nobumitsu Hanioka, Mitsuru Tanaka and Tamihide MatsunagaDrug Metabolism and Disposition January 2022, 50 (1) 17-23; DOI: https://doi.org/10.1124/dmd.121.000605
R
Ragueneau-Majlessi, Isabelle
- You have accessPharmacokinetic Drug-Drug Interactions with Drugs Approved by the US Food and Drug Administration in 2020: Mechanistic Understanding and Clinical RecommendationsJingjing Yu, Yan Wang and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition January 2022, 50 (1) 1-7; DOI: https://doi.org/10.1124/dmd.121.000401
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Savage, Mark
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
Scott, Emily E.
- You have accessCytochrome P450 Binding and Bioactivation of Tumor-Targeted Duocarmycin AgentsAaron G. Bart, Goreti Morais, Venu R. Vangala, Paul M. Loadman, Klaus Pors and Emily E. ScottDrug Metabolism and Disposition January 2022, 50 (1) 49-57; DOI: https://doi.org/10.1124/dmd.121.000642
Staggs, Vincent S.
- You have accessOntogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of LiverJ. Steven Leeder, Jean C. Dinh, Andrea Gaedigk, Vincent S. Staggs, Bhagwat Prasad and Robin E. PearceDrug Metabolism and Disposition January 2022, 50 (1) 24-32; DOI: https://doi.org/10.1124/dmd.121.000623
Stillhart, Cordula
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
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Tanaka, Mitsuru
- You have accessSimultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase–Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell–Derived Small Intestinal Epithelial CellsTakashi Kitaguchi, Taisei Mizota, Mina Ito, Katsutoshi Ohno, Kazuhiro Kobayashi, Isamu Ogawa, Shimeng Qiu, Takahiro Iwao, Nobumitsu Hanioka, Mitsuru Tanaka and Tamihide MatsunagaDrug Metabolism and Disposition January 2022, 50 (1) 17-23; DOI: https://doi.org/10.1124/dmd.121.000605
Thurber, Greg M.
- You have accessSimulating the Selection of Resistant Cells with Bystander Killing and Antibody Coadministration in Heterogeneous Human Epidermal Growth Factor Receptor 2–Positive TumorsBruna Menezes, Jennifer J. Linderman and Greg M. ThurberDrug Metabolism and Disposition January 2022, 50 (1) 8-16; DOI: https://doi.org/10.1124/dmd.121.000503
Tuerck, Dietrich
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
Tukey, Robert H.
- You have accessIntestinal UDP-Glucuronosyltransferase 1A1 and Protection against Irinotecan-Induced Toxicity in a Novel UDP-Glucuronosyltransferase 1A1 Tissue-Specific Humanized Mouse ModelElvira Mennillo, Xiaojing Yang, Andre A. Weber, Yoshihiro Maruo, Melanie Verreault, Olivier Barbier, Shujuan Chen and Robert H. TukeyDrug Metabolism and Disposition January 2022, 50 (1) 33-42; DOI: https://doi.org/10.1124/dmd.121.000644
U
Ullah, Mohammed
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
Umehara, Kenichi
- Open AccessAddressing Today’s Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, Andreas Günther, Katja Heinig, Christophe Husser, Heidemarie Kletzl, Nicole Kratochwil, Lutz Mueller, Mark Savage, Cordula Stillhart, Dietrich Tuerck, Mohammed Ullah, Kenichi Umehara and Agnès PoirierDrug Metabolism and Disposition January 2022, 50 (1) 65-75; DOI: https://doi.org/10.1124/dmd.121.000563
V
Vangala, Venu R.
- You have accessCytochrome P450 Binding and Bioactivation of Tumor-Targeted Duocarmycin AgentsAaron G. Bart, Goreti Morais, Venu R. Vangala, Paul M. Loadman, Klaus Pors and Emily E. ScottDrug Metabolism and Disposition January 2022, 50 (1) 49-57; DOI: https://doi.org/10.1124/dmd.121.000642
Verreault, Melanie
- You have accessIntestinal UDP-Glucuronosyltransferase 1A1 and Protection against Irinotecan-Induced Toxicity in a Novel UDP-Glucuronosyltransferase 1A1 Tissue-Specific Humanized Mouse ModelElvira Mennillo, Xiaojing Yang, Andre A. Weber, Yoshihiro Maruo, Melanie Verreault, Olivier Barbier, Shujuan Chen and Robert H. TukeyDrug Metabolism and Disposition January 2022, 50 (1) 33-42; DOI: https://doi.org/10.1124/dmd.121.000644
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Wang, Danxin
- You have accessTranscriptional Regulation of Carboxylesterase 1 in Human Liver: Role of the Nuclear Receptor Subfamily 1 Group H Member 3 and Its Splice IsoformsJoseph M. Collins, Rong Lu, Xinwen Wang, Hao-Jie Zhu and Danxin WangDrug Metabolism and Disposition January 2022, 50 (1) 43-48; DOI: https://doi.org/10.1124/dmd.121.000649
Wang, Xinwen
- You have accessTranscriptional Regulation of Carboxylesterase 1 in Human Liver: Role of the Nuclear Receptor Subfamily 1 Group H Member 3 and Its Splice IsoformsJoseph M. Collins, Rong Lu, Xinwen Wang, Hao-Jie Zhu and Danxin WangDrug Metabolism and Disposition January 2022, 50 (1) 43-48; DOI: https://doi.org/10.1124/dmd.121.000649
Wang, Yan
- You have accessPharmacokinetic Drug-Drug Interactions with Drugs Approved by the US Food and Drug Administration in 2020: Mechanistic Understanding and Clinical RecommendationsJingjing Yu, Yan Wang and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition January 2022, 50 (1) 1-7; DOI: https://doi.org/10.1124/dmd.121.000401
Weber, Andre A.
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Y
Yang, Xiaojing
- You have accessIntestinal UDP-Glucuronosyltransferase 1A1 and Protection against Irinotecan-Induced Toxicity in a Novel UDP-Glucuronosyltransferase 1A1 Tissue-Specific Humanized Mouse ModelElvira Mennillo, Xiaojing Yang, Andre A. Weber, Yoshihiro Maruo, Melanie Verreault, Olivier Barbier, Shujuan Chen and Robert H. TukeyDrug Metabolism and Disposition January 2022, 50 (1) 33-42; DOI: https://doi.org/10.1124/dmd.121.000644
Yin, Jiayi
- You have accessFeature, Function, and Information of Drug Transporter–Related DatabasesJiayi Yin, Fengcheng Li, Zhaorong Li, Lushan Yu, Feng Zhu and Su ZengDrug Metabolism and Disposition January 2022, 50 (1) 76-85; DOI: https://doi.org/10.1124/dmd.121.000419
Yu, Jingjing
- You have accessPharmacokinetic Drug-Drug Interactions with Drugs Approved by the US Food and Drug Administration in 2020: Mechanistic Understanding and Clinical RecommendationsJingjing Yu, Yan Wang and Isabelle Ragueneau-MajlessiDrug Metabolism and Disposition January 2022, 50 (1) 1-7; DOI: https://doi.org/10.1124/dmd.121.000401
Yu, Lushan
- You have accessFeature, Function, and Information of Drug Transporter–Related DatabasesJiayi Yin, Fengcheng Li, Zhaorong Li, Lushan Yu, Feng Zhu and Su ZengDrug Metabolism and Disposition January 2022, 50 (1) 76-85; DOI: https://doi.org/10.1124/dmd.121.000419
Z
Zeng, Su
- You have accessFeature, Function, and Information of Drug Transporter–Related DatabasesJiayi Yin, Fengcheng Li, Zhaorong Li, Lushan Yu, Feng Zhu and Su ZengDrug Metabolism and Disposition January 2022, 50 (1) 76-85; DOI: https://doi.org/10.1124/dmd.121.000419
Zhang, Yufeng
- You have accessOverview of Current Herb–Drug Interaction DatabasesYufeng Zhang, Chung Man Ip, Yuen Sze Lai and Zhong ZuoDrug Metabolism and Disposition January 2022, 50 (1) 86-94; DOI: https://doi.org/10.1124/dmd.121.000420
Zhu, Feng
- You have accessFeature, Function, and Information of Drug Transporter–Related DatabasesJiayi Yin, Fengcheng Li, Zhaorong Li, Lushan Yu, Feng Zhu and Su ZengDrug Metabolism and Disposition January 2022, 50 (1) 76-85; DOI: https://doi.org/10.1124/dmd.121.000419
Zhu, Hao-Jie
- You have accessTranscriptional Regulation of Carboxylesterase 1 in Human Liver: Role of the Nuclear Receptor Subfamily 1 Group H Member 3 and Its Splice IsoformsJoseph M. Collins, Rong Lu, Xinwen Wang, Hao-Jie Zhu and Danxin WangDrug Metabolism and Disposition January 2022, 50 (1) 43-48; DOI: https://doi.org/10.1124/dmd.121.000649
Zuo, Zhong
- You have accessOverview of Current Herb–Drug Interaction DatabasesYufeng Zhang, Chung Man Ip, Yuen Sze Lai and Zhong ZuoDrug Metabolism and Disposition January 2022, 50 (1) 86-94; DOI: https://doi.org/10.1124/dmd.121.000420
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