Metabolic activation by oxidative metabolism | NFZ > KTZ > APAP > CPA > TGZ > AMD | Highest to lowest MDCI, representing highest to lowest levels of metabolic activation |
UGT detoxification | APAP > TGZ > KTZ = NFZ > CPA, > AMD | Lowest to highest MDCI, representing highest to lowest levels of detoxification |
SULT detoxification | APAP > TGZ > KTZ (No apparent SULT detoxification was observed for AMD, NFZ, CPA, NFZ) | Lowest to highest MDCI, representing highest to lowest levels of detoxification |
GST detoxification | TGZ > APAP > CPA = KTZ = NFZ > AMD | Lowest to highest MDCI, representing highest to lowest levels of detoxification |