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Index by author

April 01, 2022; Volume 50,Issue 4

A

  1. Abduljalil, Khaled

    1. Prediction of Maternal and Fetoplacental Concentrations of Cefazolin, Cefuroxime, and Amoxicillin during Pregnancy Using Bottom-Up Physiologically Based Pharmacokinetic Models
      Khaled Abduljalil, Jia Ning, Amita Pansari, Xian Pan and Masoud Jamei
      Drug Metabolism and Disposition April 2022, 50 (4) 386-400; DOI: https://doi.org/10.1124/dmd.121.000711

  2. Altares, R.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  3. Aviles, P.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  4. Awali, Saamera

    1. The Complicated Role of Nuclear Factor Erythroid-Derived 2-Like 2 in Allergy and Asthma
      Cheryl E. Rockwell, Yining Jin, Allison P. Boss, Luca M. Kaiser and Saamera Awali
      Drug Metabolism and Disposition April 2022, 50 (4) 500-507; DOI: https://doi.org/10.1124/dmd.121.000414

B

  1. Backes, Wayne L.

    1. Proteomic and Bioinformatics Analysis of Membrane Lipid Domains after Brij 98 Solubilization of Uninduced and Phenobarbital-Induced Rat Liver Microsomes: Defining the Membrane Localization of the P450 Enzyme System
      James R. Reed, Jessie J. Guidry and Wayne L. Backes
      Drug Metabolism and Disposition April 2022, 50 (4) 374-385; DOI: https://doi.org/10.1124/dmd.121.000752

  2. Badolo, Lassina

    1. Open Access
      Metabolic Profiling of S-praziquantel: Structure Elucidation Using the Crystalline Sponge Method in Combination with Mass Spectrometry and Nuclear Magnetic Resonance
      Lara Rosenberger, Judith Jenniches, Carolina von Essen, Anupam Khutia, Clemens Kühn, Andreas Marx, Katrin Georgi, Anna K. H. Hirsch, Rolf W. Hartmann and Lassina Badolo
      Drug Metabolism and Disposition April 2022, 50 (4) 320-326; DOI: https://doi.org/10.1124/dmd.121.000663

  3. Bai, Mengru

    1. Bilirubin Reduces the Uptake of Estrogen Precursors and the Followed Synthesis of Estradiol in Human Placental Syncytiotrophoblasts via Inhibition and Downregulation of Organic Anion Transporter 4
      Yingqiong Zhang, Yujia Chen, Binxin Dai, Mengru Bai, Shuanghui Lu, Nengming Lin, Hui Zhou and Huidi Jiang
      Drug Metabolism and Disposition April 2022, 50 (4) 341-350; DOI: https://doi.org/10.1124/dmd.121.000685

  4. Bansal, Sumit

    1. Comprehensive Predictions of Cytochrome P450 (P450)-Mediated In Vivo Cannabinoid-Drug Interactions Based on Reversible and Time-Dependent P450 Inhibition in Human Liver Microsomes
      Sumit Bansal, Mary F. Paine and Jashvant D. Unadkat
      Drug Metabolism and Disposition April 2022, 50 (4) 351-360; DOI: https://doi.org/10.1124/dmd.121.000734

  5. Beijnen, J.H.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  6. Benedit, G.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  7. Benet, Leslie Z.

    1. Does Addition of Protein to Hepatocyte or Microsomal In Vitro Incubations Provide a Useful Improvement in In Vitro-In Vivo Extrapolation Predictability?
      Tsubasa Kameyama, Jasleen K. Sodhi and Leslie Z. Benet
      Drug Metabolism and Disposition April 2022, 50 (4) 401-412; DOI: https://doi.org/10.1124/dmd.121.000677

  8. Bhattacharya, Anisha

    1. Environmental Chemical Contribution to the Modulation of Bile Acid Homeostasis and Farnesoid X Receptor Signaling
      Rulaiha E. Taylor, Anisha Bhattacharya and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 456-467; DOI: https://doi.org/10.1124/dmd.121.000388

  9. Boss, Allison P.

    1. The Complicated Role of Nuclear Factor Erythroid-Derived 2-Like 2 in Allergy and Asthma
      Cheryl E. Rockwell, Yining Jin, Allison P. Boss, Luca M. Kaiser and Saamera Awali
      Drug Metabolism and Disposition April 2022, 50 (4) 500-507; DOI: https://doi.org/10.1124/dmd.121.000414

  10. Boteju, Asela

    1. In Vitro and In Vivo Metabolism of a Novel Antimitochondrial Cancer Metabolism Agent, CPI-613, in Rat and Human
      Vijay Bhasker Reddy, Lakmal Boteju, Asela Boteju, Li Shen, Kelem Kassahun, Nageshwar Reddy, Adrian Sheldon, Sanjeev Luther and Ke Hu
      Drug Metabolism and Disposition April 2022, 50 (4) 361-373; DOI: https://doi.org/10.1124/dmd.121.000726

  11. Boteju, Lakmal

    1. In Vitro and In Vivo Metabolism of a Novel Antimitochondrial Cancer Metabolism Agent, CPI-613, in Rat and Human
      Vijay Bhasker Reddy, Lakmal Boteju, Asela Boteju, Li Shen, Kelem Kassahun, Nageshwar Reddy, Adrian Sheldon, Sanjeev Luther and Ke Hu
      Drug Metabolism and Disposition April 2022, 50 (4) 361-373; DOI: https://doi.org/10.1124/dmd.121.000726

C

  1. Chen, Liming

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

  2. Chen, Yujia

    1. Bilirubin Reduces the Uptake of Estrogen Precursors and the Followed Synthesis of Estradiol in Human Placental Syncytiotrophoblasts via Inhibition and Downregulation of Organic Anion Transporter 4
      Yingqiong Zhang, Yujia Chen, Binxin Dai, Mengru Bai, Shuanghui Lu, Nengming Lin, Hui Zhou and Huidi Jiang
      Drug Metabolism and Disposition April 2022, 50 (4) 341-350; DOI: https://doi.org/10.1124/dmd.121.000685

  3. Cherrington, Nathan J.

    1. Strategies to Diagnose Nonalcoholic Steatohepatitis: A Novel Approach to Take Advantage of Pharmacokinetic Alterations
      Solène Marie, David K.K. Tripp and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2022, 50 (4) 492-499; DOI: https://doi.org/10.1124/dmd.121.000413

  4. Choudhuri, Supratim

    1. Molecular Regulation of Bile Acid Homeostasis
      Supratim Choudhuri and Curtis D. Klaassen
      Drug Metabolism and Disposition April 2022, 50 (4) 425-455; DOI: https://doi.org/10.1124/dmd.121.000643

  5. Cuevas, C.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  6. Cui, Julia Yue

    1. Pregnane X Receptor and the Gut-Liver Axis: A Recent Update
      Moumita Dutta, Joe Jongpyo Lim and Julia Yue Cui
      Drug Metabolism and Disposition April 2022, 50 (4) 478-491; DOI: https://doi.org/10.1124/dmd.121.000415

D

  1. Dai, Binxin

    1. Bilirubin Reduces the Uptake of Estrogen Precursors and the Followed Synthesis of Estradiol in Human Placental Syncytiotrophoblasts via Inhibition and Downregulation of Organic Anion Transporter 4
      Yingqiong Zhang, Yujia Chen, Binxin Dai, Mengru Bai, Shuanghui Lu, Nengming Lin, Hui Zhou and Huidi Jiang
      Drug Metabolism and Disposition April 2022, 50 (4) 341-350; DOI: https://doi.org/10.1124/dmd.121.000685

  2. Dutta, Moumita

    1. Pregnane X Receptor and the Gut-Liver Axis: A Recent Update
      Moumita Dutta, Joe Jongpyo Lim and Julia Yue Cui
      Drug Metabolism and Disposition April 2022, 50 (4) 478-491; DOI: https://doi.org/10.1124/dmd.121.000415

E

  1. Estefan, X.E. Luepke

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

F

  1. Francesch, A.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  2. Fudio, S.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

G

  1. Georgi, Katrin

    1. Open Access
      Metabolic Profiling of S-praziquantel: Structure Elucidation Using the Crystalline Sponge Method in Combination with Mass Spectrometry and Nuclear Magnetic Resonance
      Lara Rosenberger, Judith Jenniches, Carolina von Essen, Anupam Khutia, Clemens Kühn, Andreas Marx, Katrin Georgi, Anna K. H. Hirsch, Rolf W. Hartmann and Lassina Badolo
      Drug Metabolism and Disposition April 2022, 50 (4) 320-326; DOI: https://doi.org/10.1124/dmd.121.000663

  2. Guidry, Jessie J.

    1. Proteomic and Bioinformatics Analysis of Membrane Lipid Domains after Brij 98 Solubilization of Uninduced and Phenobarbital-Induced Rat Liver Microsomes: Defining the Membrane Localization of the P450 Enzyme System
      James R. Reed, Jessie J. Guidry and Wayne L. Backes
      Drug Metabolism and Disposition April 2022, 50 (4) 374-385; DOI: https://doi.org/10.1124/dmd.121.000752

  3. Guo, Grace L.

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416
    2. Environmental Chemical Contribution to the Modulation of Bile Acid Homeostasis and Farnesoid X Receptor Signaling
      Rulaiha E. Taylor, Anisha Bhattacharya and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 456-467; DOI: https://doi.org/10.1124/dmd.121.000388

H

  1. Hartmann, Rolf W.

    1. Open Access
      Metabolic Profiling of S-praziquantel: Structure Elucidation Using the Crystalline Sponge Method in Combination with Mass Spectrometry and Nuclear Magnetic Resonance
      Lara Rosenberger, Judith Jenniches, Carolina von Essen, Anupam Khutia, Clemens Kühn, Andreas Marx, Katrin Georgi, Anna K. H. Hirsch, Rolf W. Hartmann and Lassina Badolo
      Drug Metabolism and Disposition April 2022, 50 (4) 320-326; DOI: https://doi.org/10.1124/dmd.121.000663

  2. Hirsch, Anna K. H.

    1. Open Access
      Metabolic Profiling of S-praziquantel: Structure Elucidation Using the Crystalline Sponge Method in Combination with Mass Spectrometry and Nuclear Magnetic Resonance
      Lara Rosenberger, Judith Jenniches, Carolina von Essen, Anupam Khutia, Clemens Kühn, Andreas Marx, Katrin Georgi, Anna K. H. Hirsch, Rolf W. Hartmann and Lassina Badolo
      Drug Metabolism and Disposition April 2022, 50 (4) 320-326; DOI: https://doi.org/10.1124/dmd.121.000663

  3. Hu, Ke

    1. In Vitro and In Vivo Metabolism of a Novel Antimitochondrial Cancer Metabolism Agent, CPI-613, in Rat and Human
      Vijay Bhasker Reddy, Lakmal Boteju, Asela Boteju, Li Shen, Kelem Kassahun, Nageshwar Reddy, Adrian Sheldon, Sanjeev Luther and Ke Hu
      Drug Metabolism and Disposition April 2022, 50 (4) 361-373; DOI: https://doi.org/10.1124/dmd.121.000726

J

  1. Jamei, Masoud

    1. Prediction of Maternal and Fetoplacental Concentrations of Cefazolin, Cefuroxime, and Amoxicillin during Pregnancy Using Bottom-Up Physiologically Based Pharmacokinetic Models
      Khaled Abduljalil, Jia Ning, Amita Pansari, Xian Pan and Masoud Jamei
      Drug Metabolism and Disposition April 2022, 50 (4) 386-400; DOI: https://doi.org/10.1124/dmd.121.000711

  2. Jenniches, Judith

    1. Open Access
      Metabolic Profiling of S-praziquantel: Structure Elucidation Using the Crystalline Sponge Method in Combination with Mass Spectrometry and Nuclear Magnetic Resonance
      Lara Rosenberger, Judith Jenniches, Carolina von Essen, Anupam Khutia, Clemens Kühn, Andreas Marx, Katrin Georgi, Anna K. H. Hirsch, Rolf W. Hartmann and Lassina Badolo
      Drug Metabolism and Disposition April 2022, 50 (4) 320-326; DOI: https://doi.org/10.1124/dmd.121.000663

  3. Jiang, Huidi

    1. Bilirubin Reduces the Uptake of Estrogen Precursors and the Followed Synthesis of Estradiol in Human Placental Syncytiotrophoblasts via Inhibition and Downregulation of Organic Anion Transporter 4
      Yingqiong Zhang, Yujia Chen, Binxin Dai, Mengru Bai, Shuanghui Lu, Nengming Lin, Hui Zhou and Huidi Jiang
      Drug Metabolism and Disposition April 2022, 50 (4) 341-350; DOI: https://doi.org/10.1124/dmd.121.000685

  4. Jin, Yining

    1. The Complicated Role of Nuclear Factor Erythroid-Derived 2-Like 2 in Allergy and Asthma
      Cheryl E. Rockwell, Yining Jin, Allison P. Boss, Luca M. Kaiser and Saamera Awali
      Drug Metabolism and Disposition April 2022, 50 (4) 500-507; DOI: https://doi.org/10.1124/dmd.121.000414

K

  1. Kagan, Leonid

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

  2. Kaiser, Luca M.

    1. The Complicated Role of Nuclear Factor Erythroid-Derived 2-Like 2 in Allergy and Asthma
      Cheryl E. Rockwell, Yining Jin, Allison P. Boss, Luca M. Kaiser and Saamera Awali
      Drug Metabolism and Disposition April 2022, 50 (4) 500-507; DOI: https://doi.org/10.1124/dmd.121.000414

  3. Kameyama, Tsubasa

    1. Does Addition of Protein to Hepatocyte or Microsomal In Vitro Incubations Provide a Useful Improvement in In Vitro-In Vivo Extrapolation Predictability?
      Tsubasa Kameyama, Jasleen K. Sodhi and Leslie Z. Benet
      Drug Metabolism and Disposition April 2022, 50 (4) 401-412; DOI: https://doi.org/10.1124/dmd.121.000677

  4. Kassahun, Kelem

    1. In Vitro and In Vivo Metabolism of a Novel Antimitochondrial Cancer Metabolism Agent, CPI-613, in Rat and Human
      Vijay Bhasker Reddy, Lakmal Boteju, Asela Boteju, Li Shen, Kelem Kassahun, Nageshwar Reddy, Adrian Sheldon, Sanjeev Luther and Ke Hu
      Drug Metabolism and Disposition April 2022, 50 (4) 361-373; DOI: https://doi.org/10.1124/dmd.121.000726

  5. Khutia, Anupam

    1. Open Access
      Metabolic Profiling of S-praziquantel: Structure Elucidation Using the Crystalline Sponge Method in Combination with Mass Spectrometry and Nuclear Magnetic Resonance
      Lara Rosenberger, Judith Jenniches, Carolina von Essen, Anupam Khutia, Clemens Kühn, Andreas Marx, Katrin Georgi, Anna K. H. Hirsch, Rolf W. Hartmann and Lassina Badolo
      Drug Metabolism and Disposition April 2022, 50 (4) 320-326; DOI: https://doi.org/10.1124/dmd.121.000663

  6. Klaassen, Curtis D.

    1. Molecular Regulation of Bile Acid Homeostasis
      Supratim Choudhuri and Curtis D. Klaassen
      Drug Metabolism and Disposition April 2022, 50 (4) 425-455; DOI: https://doi.org/10.1124/dmd.121.000643

  7. Kong, Bo

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

  8. Kühn, Clemens

    1. Open Access
      Metabolic Profiling of S-praziquantel: Structure Elucidation Using the Crystalline Sponge Method in Combination with Mass Spectrometry and Nuclear Magnetic Resonance
      Lara Rosenberger, Judith Jenniches, Carolina von Essen, Anupam Khutia, Clemens Kühn, Andreas Marx, Katrin Georgi, Anna K. H. Hirsch, Rolf W. Hartmann and Lassina Badolo
      Drug Metabolism and Disposition April 2022, 50 (4) 320-326; DOI: https://doi.org/10.1124/dmd.121.000663

L

  1. Li, Albert

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

  2. Li, Linhao

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

  3. Lim, Joe Jongpyo

    1. Pregnane X Receptor and the Gut-Liver Axis: A Recent Update
      Moumita Dutta, Joe Jongpyo Lim and Julia Yue Cui
      Drug Metabolism and Disposition April 2022, 50 (4) 478-491; DOI: https://doi.org/10.1124/dmd.121.000415

  4. Lin, Nengming

    1. Bilirubin Reduces the Uptake of Estrogen Precursors and the Followed Synthesis of Estradiol in Human Placental Syncytiotrophoblasts via Inhibition and Downregulation of Organic Anion Transporter 4
      Yingqiong Zhang, Yujia Chen, Binxin Dai, Mengru Bai, Shuanghui Lu, Nengming Lin, Hui Zhou and Huidi Jiang
      Drug Metabolism and Disposition April 2022, 50 (4) 341-350; DOI: https://doi.org/10.1124/dmd.121.000685

  5. Lu, Jie

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

  6. Lu, Shuanghui

    1. Bilirubin Reduces the Uptake of Estrogen Precursors and the Followed Synthesis of Estradiol in Human Placental Syncytiotrophoblasts via Inhibition and Downregulation of Organic Anion Transporter 4
      Yingqiong Zhang, Yujia Chen, Binxin Dai, Mengru Bai, Shuanghui Lu, Nengming Lin, Hui Zhou and Huidi Jiang
      Drug Metabolism and Disposition April 2022, 50 (4) 341-350; DOI: https://doi.org/10.1124/dmd.121.000685

  7. Lubomirov, R.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  8. Luther, Sanjeev

    1. In Vitro and In Vivo Metabolism of a Novel Antimitochondrial Cancer Metabolism Agent, CPI-613, in Rat and Human
      Vijay Bhasker Reddy, Lakmal Boteju, Asela Boteju, Li Shen, Kelem Kassahun, Nageshwar Reddy, Adrian Sheldon, Sanjeev Luther and Ke Hu
      Drug Metabolism and Disposition April 2022, 50 (4) 361-373; DOI: https://doi.org/10.1124/dmd.121.000726

M

  1. Marie, Solène

    1. Strategies to Diagnose Nonalcoholic Steatohepatitis: A Novel Approach to Take Advantage of Pharmacokinetic Alterations
      Solène Marie, David K.K. Tripp and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2022, 50 (4) 492-499; DOI: https://doi.org/10.1124/dmd.121.000413

  2. Márquez del Pino, F. M.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  3. Marx, Andreas

    1. Open Access
      Metabolic Profiling of S-praziquantel: Structure Elucidation Using the Crystalline Sponge Method in Combination with Mass Spectrometry and Nuclear Magnetic Resonance
      Lara Rosenberger, Judith Jenniches, Carolina von Essen, Anupam Khutia, Clemens Kühn, Andreas Marx, Katrin Georgi, Anna K. H. Hirsch, Rolf W. Hartmann and Lassina Badolo
      Drug Metabolism and Disposition April 2022, 50 (4) 320-326; DOI: https://doi.org/10.1124/dmd.121.000663

N

  1. Nan-Offeringa, L.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  2. Ning, Jia

    1. Prediction of Maternal and Fetoplacental Concentrations of Cefazolin, Cefuroxime, and Amoxicillin during Pregnancy Using Bottom-Up Physiologically Based Pharmacokinetic Models
      Khaled Abduljalil, Jia Ning, Amita Pansari, Xian Pan and Masoud Jamei
      Drug Metabolism and Disposition April 2022, 50 (4) 386-400; DOI: https://doi.org/10.1124/dmd.121.000711

O

  1. Obach, R. Scott

    1. Linezolid Metabolism Is Catalyzed by Cytochrome P450 2J2, 4F2, and 1B1
      R. Scott Obach
      Drug Metabolism and Disposition April 2022, 50 (4) 413-421; DOI: https://doi.org/10.1124/dmd.121.000776

P

  1. Paine, Mary F.

    1. Comprehensive Predictions of Cytochrome P450 (P450)-Mediated In Vivo Cannabinoid-Drug Interactions Based on Reversible and Time-Dependent P450 Inhibition in Human Liver Microsomes
      Sumit Bansal, Mary F. Paine and Jashvant D. Unadkat
      Drug Metabolism and Disposition April 2022, 50 (4) 351-360; DOI: https://doi.org/10.1124/dmd.121.000734

  2. Pan, Xian

    1. Prediction of Maternal and Fetoplacental Concentrations of Cefazolin, Cefuroxime, and Amoxicillin during Pregnancy Using Bottom-Up Physiologically Based Pharmacokinetic Models
      Khaled Abduljalil, Jia Ning, Amita Pansari, Xian Pan and Masoud Jamei
      Drug Metabolism and Disposition April 2022, 50 (4) 386-400; DOI: https://doi.org/10.1124/dmd.121.000711

  3. Pansari, Amita

    1. Prediction of Maternal and Fetoplacental Concentrations of Cefazolin, Cefuroxime, and Amoxicillin during Pregnancy Using Bottom-Up Physiologically Based Pharmacokinetic Models
      Khaled Abduljalil, Jia Ning, Amita Pansari, Xian Pan and Masoud Jamei
      Drug Metabolism and Disposition April 2022, 50 (4) 386-400; DOI: https://doi.org/10.1124/dmd.121.000711

  4. Park, Celine

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

  5. Piekos, Stephanie

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

R

  1. Reddy, Nageshwar

    1. In Vitro and In Vivo Metabolism of a Novel Antimitochondrial Cancer Metabolism Agent, CPI-613, in Rat and Human
      Vijay Bhasker Reddy, Lakmal Boteju, Asela Boteju, Li Shen, Kelem Kassahun, Nageshwar Reddy, Adrian Sheldon, Sanjeev Luther and Ke Hu
      Drug Metabolism and Disposition April 2022, 50 (4) 361-373; DOI: https://doi.org/10.1124/dmd.121.000726

  2. Reddy, Vijay Bhasker

    1. In Vitro and In Vivo Metabolism of a Novel Antimitochondrial Cancer Metabolism Agent, CPI-613, in Rat and Human
      Vijay Bhasker Reddy, Lakmal Boteju, Asela Boteju, Li Shen, Kelem Kassahun, Nageshwar Reddy, Adrian Sheldon, Sanjeev Luther and Ke Hu
      Drug Metabolism and Disposition April 2022, 50 (4) 361-373; DOI: https://doi.org/10.1124/dmd.121.000726

  3. Reed, James R.

    1. Proteomic and Bioinformatics Analysis of Membrane Lipid Domains after Brij 98 Solubilization of Uninduced and Phenobarbital-Induced Rat Liver Microsomes: Defining the Membrane Localization of the P450 Enzyme System
      James R. Reed, Jessie J. Guidry and Wayne L. Backes
      Drug Metabolism and Disposition April 2022, 50 (4) 374-385; DOI: https://doi.org/10.1124/dmd.121.000752

  4. Rizzolo, Daniel

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

  5. Rockwell, Cheryl E.

    1. The Complicated Role of Nuclear Factor Erythroid-Derived 2-Like 2 in Allergy and Asthma
      Cheryl E. Rockwell, Yining Jin, Allison P. Boss, Luca M. Kaiser and Saamera Awali
      Drug Metabolism and Disposition April 2022, 50 (4) 500-507; DOI: https://doi.org/10.1124/dmd.121.000414

  6. Rosenberger, Lara

    1. Open Access
      Metabolic Profiling of S-praziquantel: Structure Elucidation Using the Crystalline Sponge Method in Combination with Mass Spectrometry and Nuclear Magnetic Resonance
      Lara Rosenberger, Judith Jenniches, Carolina von Essen, Anupam Khutia, Clemens Kühn, Andreas Marx, Katrin Georgi, Anna K. H. Hirsch, Rolf W. Hartmann and Lassina Badolo
      Drug Metabolism and Disposition April 2022, 50 (4) 320-326; DOI: https://doi.org/10.1124/dmd.121.000663

  7. Rosing, H.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

S

  1. Schellens, J.H.M.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  2. Sheldon, Adrian

    1. In Vitro and In Vivo Metabolism of a Novel Antimitochondrial Cancer Metabolism Agent, CPI-613, in Rat and Human
      Vijay Bhasker Reddy, Lakmal Boteju, Asela Boteju, Li Shen, Kelem Kassahun, Nageshwar Reddy, Adrian Sheldon, Sanjeev Luther and Ke Hu
      Drug Metabolism and Disposition April 2022, 50 (4) 361-373; DOI: https://doi.org/10.1124/dmd.121.000726

  3. Shen, Li

    1. In Vitro and In Vivo Metabolism of a Novel Antimitochondrial Cancer Metabolism Agent, CPI-613, in Rat and Human
      Vijay Bhasker Reddy, Lakmal Boteju, Asela Boteju, Li Shen, Kelem Kassahun, Nageshwar Reddy, Adrian Sheldon, Sanjeev Luther and Ke Hu
      Drug Metabolism and Disposition April 2022, 50 (4) 361-373; DOI: https://doi.org/10.1124/dmd.121.000726

  4. Shi, Jian

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

  5. Siemiątkowska, Anna

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

  6. Sodhi, Jasleen K.

    1. Does Addition of Protein to Hepatocyte or Microsomal In Vitro Incubations Provide a Useful Improvement in In Vitro-In Vivo Extrapolation Predictability?
      Tsubasa Kameyama, Jasleen K. Sodhi and Leslie Z. Benet
      Drug Metabolism and Disposition April 2022, 50 (4) 401-412; DOI: https://doi.org/10.1124/dmd.121.000677

T

  1. Taylor, Rulaiha E.

    1. Environmental Chemical Contribution to the Modulation of Bile Acid Homeostasis and Farnesoid X Receptor Signaling
      Rulaiha E. Taylor, Anisha Bhattacharya and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 456-467; DOI: https://doi.org/10.1124/dmd.121.000388

  2. Tibben, M.M.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  3. Tripp, David K.K.

    1. Strategies to Diagnose Nonalcoholic Steatohepatitis: A Novel Approach to Take Advantage of Pharmacokinetic Alterations
      Solène Marie, David K.K. Tripp and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2022, 50 (4) 492-499; DOI: https://doi.org/10.1124/dmd.121.000413

U

  1. Unadkat, Jashvant D.

    1. Comprehensive Predictions of Cytochrome P450 (P450)-Mediated In Vivo Cannabinoid-Drug Interactions Based on Reversible and Time-Dependent P450 Inhibition in Human Liver Microsomes
      Sumit Bansal, Mary F. Paine and Jashvant D. Unadkat
      Drug Metabolism and Disposition April 2022, 50 (4) 351-360; DOI: https://doi.org/10.1124/dmd.121.000734

V

  1. van Andel, L.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  2. Vansell, Nichole R.

    1. Open Access
      Mechanisms by Which Inducers of Drug Metabolizing Enzymes Alter Thyroid Hormones in Rats
      Nichole R. Vansell
      Drug Metabolism and Disposition April 2022, 50 (4) 508-517; DOI: https://doi.org/10.1124/dmd.121.000498

  3. von Essen, Carolina

    1. Open Access
      Metabolic Profiling of S-praziquantel: Structure Elucidation Using the Crystalline Sponge Method in Combination with Mass Spectrometry and Nuclear Magnetic Resonance
      Lara Rosenberger, Judith Jenniches, Carolina von Essen, Anupam Khutia, Clemens Kühn, Andreas Marx, Katrin Georgi, Anna K. H. Hirsch, Rolf W. Hartmann and Lassina Badolo
      Drug Metabolism and Disposition April 2022, 50 (4) 320-326; DOI: https://doi.org/10.1124/dmd.121.000663

W

  1. Wang, Hongbing

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

Y

  1. Yang, Qian

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

Z

  1. Zeaiter, A.

    1. Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
      P. Aviles, R. Altares, L. van Andel, R. Lubomirov, S. Fudio, H. Rosing, F. M. Márquez del Pino, M.M. Tibben, G. Benedit, L. Nan-Offeringa, X.E. Luepke Estefan, A. Francesch, A. Zeaiter, C. Cuevas, J.H.M. Schellens and J.H. Beijnen
      Drug Metabolism and Disposition April 2022, 50 (4) 327-340; DOI: https://doi.org/10.1124/dmd.121.000668

  2. Zhang, Yingqiong

    1. Bilirubin Reduces the Uptake of Estrogen Precursors and the Followed Synthesis of Estradiol in Human Placental Syncytiotrophoblasts via Inhibition and Downregulation of Organic Anion Transporter 4
      Yingqiong Zhang, Yujia Chen, Binxin Dai, Mengru Bai, Shuanghui Lu, Nengming Lin, Hui Zhou and Huidi Jiang
      Drug Metabolism and Disposition April 2022, 50 (4) 341-350; DOI: https://doi.org/10.1124/dmd.121.000685

  3. Zhong, Xiaobo

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416

  4. Zhou, Hui

    1. Bilirubin Reduces the Uptake of Estrogen Precursors and the Followed Synthesis of Estradiol in Human Placental Syncytiotrophoblasts via Inhibition and Downregulation of Organic Anion Transporter 4
      Yingqiong Zhang, Yujia Chen, Binxin Dai, Mengru Bai, Shuanghui Lu, Nengming Lin, Hui Zhou and Huidi Jiang
      Drug Metabolism and Disposition April 2022, 50 (4) 341-350; DOI: https://doi.org/10.1124/dmd.121.000685

  5. Zhu, Hao-jie

    1. Effects of Overexpression of Fibroblast Growth Factor 15/19 on Hepatic Drug Metabolizing Enzymes
      Daniel Rizzolo, Bo Kong, Stephanie Piekos, Liming Chen, Xiaobo Zhong, Jie Lu, Jian Shi, Hao-jie Zhu, Qian Yang, Albert Li, Linhao Li, Hongbing Wang, Anna Siemiątkowska, Celine Park, Leonid Kagan and Grace L. Guo
      Drug Metabolism and Disposition April 2022, 50 (4) 468-477; DOI: https://doi.org/10.1124/dmd.121.000416
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