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Index by author

May 01, 2022; Volume 50,Issue 5

B

  1. Bao, Yifan

    1. Alterations of Cytochrome P450–Mediated Drug Metabolism during Liver Repair and Regeneration after Acetaminophen-Induced Liver Injury in Mice
      Yifan Bao, Mi Phan, Junjie Zhu, Xiaochao Ma, José E. Manautou and Xiao-bo Zhong
      Drug Metabolism and Disposition May 2022, 50 (5) 694-703; DOI: https://doi.org/10.1124/dmd.121.000459

  2. Bi, Huichang

    1. Novel Clinical Biomarkers for Drug-Induced Liver Injury
      Youhao Chen, Shaoxing Guan, Yanping Guan, Siyuan Tang, Yanying Zhou, Xueding Wang, Huichang Bi and Min Huang
      Drug Metabolism and Disposition May 2022, 50 (5) 671-684; DOI: https://doi.org/10.1124/dmd.121.000732
    2. Nuclear Receptor-Mediated Hepatomegaly and Liver Regeneration: An Update
      Pengfei Zhao, Shicheng Fan, Yue Gao, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2022, 50 (5) 636-645; DOI: https://doi.org/10.1124/dmd.121.000454

  3. Boras, Britton

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

C

  1. Cai, Weimin

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

  2. Chan, Eric Chun Yong

    1. Direct and Sequential Bioactivation of Pemigatinib to Reactive Iminium Ion Intermediates Culminates in Mechanism-Based Inactivation of Cytochrome P450 3A
      Lloyd Wei Tat Tang, Wan Wei, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Hao Fan and Eric Chun Yong Chan
      Drug Metabolism and Disposition May 2022, 50 (5) 529-540; DOI: https://doi.org/10.1124/dmd.121.000804

  3. Chen, Youhao

    1. Novel Clinical Biomarkers for Drug-Induced Liver Injury
      Youhao Chen, Shaoxing Guan, Yanping Guan, Siyuan Tang, Yanying Zhou, Xueding Wang, Huichang Bi and Min Huang
      Drug Metabolism and Disposition May 2022, 50 (5) 671-684; DOI: https://doi.org/10.1124/dmd.121.000732

  4. Chowdhury, Swapan K.

    1. Open Access
      Determination of Acyl-, O-, and N-Glucuronide Using Chemical Derivatization Coupled with Liquid Chromatography–High-Resolution Mass Spectrometry
      Yukuang Guo, Abhi Shah, Eugene Oh, Swapan K. Chowdhury and Xiaochun Zhu
      Drug Metabolism and Disposition May 2022, 50 (5) 716-724; DOI: https://doi.org/10.1124/dmd.122.000832

D

  1. Dahal, Upendra P.

    1. Absorption, Distribution, Metabolism, and Excretion of [14C]-Sotorasib in Rats and Dogs: Interspecies Differences in Absorption, Protein Conjugation and Metabolism
      Upendra P. Dahal, Brooke M. Rock, John Rodgers, Xiaomeng Shen, Zhe Wang and Jan L. Wahlstrom
      Drug Metabolism and Disposition May 2022, 50 (5) 600-612; DOI: https://doi.org/10.1124/dmd.121.000798

  2. Dantonio, Alyssa L.

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

  3. Di, Li

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

  4. Du, Wandi

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

E

  1. Ekiciler, Aynur

    1. Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Florian Klammers, Andreas Goetschi, Aynur Ekiciler, Isabelle Walter, Neil Parrott, Stephen Fowler and Kenichi Umehara
      Drug Metabolism and Disposition May 2022, 50 (5) 566-575; DOI: https://doi.org/10.1124/dmd.121.000765

  2. Eng, Heather

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

F

  1. Fan, Hao

    1. Direct and Sequential Bioactivation of Pemigatinib to Reactive Iminium Ion Intermediates Culminates in Mechanism-Based Inactivation of Cytochrome P450 3A
      Lloyd Wei Tat Tang, Wan Wei, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Hao Fan and Eric Chun Yong Chan
      Drug Metabolism and Disposition May 2022, 50 (5) 529-540; DOI: https://doi.org/10.1124/dmd.121.000804

  2. Fan, Shicheng

    1. Nuclear Receptor-Mediated Hepatomegaly and Liver Regeneration: An Update
      Pengfei Zhao, Shicheng Fan, Yue Gao, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2022, 50 (5) 636-645; DOI: https://doi.org/10.1124/dmd.121.000454

  3. Fowler, Stephen

    1. Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Florian Klammers, Andreas Goetschi, Aynur Ekiciler, Isabelle Walter, Neil Parrott, Stephen Fowler and Kenichi Umehara
      Drug Metabolism and Disposition May 2022, 50 (5) 566-575; DOI: https://doi.org/10.1124/dmd.121.000765

G

  1. Gao, Lu

    1. E4BP4 Regulates Hepatic Solute Carrier Family 2 Member 9 and Uric Acid Disposition in Mice
      Zhigang Wang, Lu Gao, Shujing Ren, Guanghui Sun, Yanke Lin, Shuai Wang and Baojian Wu
      Drug Metabolism and Disposition May 2022, 50 (5) 591-599; DOI: https://doi.org/10.1124/dmd.121.000790

  2. Gao, Yue

    1. Nuclear Receptor-Mediated Hepatomegaly and Liver Regeneration: An Update
      Pengfei Zhao, Shicheng Fan, Yue Gao, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2022, 50 (5) 636-645; DOI: https://doi.org/10.1124/dmd.121.000454

  3. Ge, Guangbo

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

  4. Goetschi, Andreas

    1. Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Florian Klammers, Andreas Goetschi, Aynur Ekiciler, Isabelle Walter, Neil Parrott, Stephen Fowler and Kenichi Umehara
      Drug Metabolism and Disposition May 2022, 50 (5) 566-575; DOI: https://doi.org/10.1124/dmd.121.000765

  5. Gonzalez, Frank J.

    1. Withaferin A in the Treatment of Liver Diseases: Progress and Pharmacokinetic Insights
      Yangliu Xia, Mingrui Yan, Ping Wang, Keisuke Hamada, Nana Yan, Haiping Hao, Frank J. Gonzalez and Tingting Yan
      Drug Metabolism and Disposition May 2022, 50 (5) 685-693; DOI: https://doi.org/10.1124/dmd.121.000455

  6. Gu, Ruizhi

    1. Roles of Cofactors in Drug-Induced Liver Injury: Drug Metabolism and Beyond
      Ruizhi Gu, Alina Liang, Grace Liao, Isabelle To, Amina Shehu and Xiaochao Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 646-654; DOI: https://doi.org/10.1124/dmd.121.000457

  7. Guan, Shaoxing

    1. Novel Clinical Biomarkers for Drug-Induced Liver Injury
      Youhao Chen, Shaoxing Guan, Yanping Guan, Siyuan Tang, Yanying Zhou, Xueding Wang, Huichang Bi and Min Huang
      Drug Metabolism and Disposition May 2022, 50 (5) 671-684; DOI: https://doi.org/10.1124/dmd.121.000732

  8. Guan, Yanping

    1. Novel Clinical Biomarkers for Drug-Induced Liver Injury
      Youhao Chen, Shaoxing Guan, Yanping Guan, Siyuan Tang, Yanying Zhou, Xueding Wang, Huichang Bi and Min Huang
      Drug Metabolism and Disposition May 2022, 50 (5) 671-684; DOI: https://doi.org/10.1124/dmd.121.000732

  9. Guo, Yukuang

    1. Open Access
      Determination of Acyl-, O-, and N-Glucuronide Using Chemical Derivatization Coupled with Liquid Chromatography–High-Resolution Mass Spectrometry
      Yukuang Guo, Abhi Shah, Eugene Oh, Swapan K. Chowdhury and Xiaochun Zhu
      Drug Metabolism and Disposition May 2022, 50 (5) 716-724; DOI: https://doi.org/10.1124/dmd.122.000832

H

  1. Hamada, Keisuke

    1. Withaferin A in the Treatment of Liver Diseases: Progress and Pharmacokinetic Insights
      Yangliu Xia, Mingrui Yan, Ping Wang, Keisuke Hamada, Nana Yan, Haiping Hao, Frank J. Gonzalez and Tingting Yan
      Drug Metabolism and Disposition May 2022, 50 (5) 685-693; DOI: https://doi.org/10.1124/dmd.121.000455

  2. Hao, Haiping

    1. Withaferin A in the Treatment of Liver Diseases: Progress and Pharmacokinetic Insights
      Yangliu Xia, Mingrui Yan, Ping Wang, Keisuke Hamada, Nana Yan, Haiping Hao, Frank J. Gonzalez and Tingting Yan
      Drug Metabolism and Disposition May 2022, 50 (5) 685-693; DOI: https://doi.org/10.1124/dmd.121.000455

  3. Hu, Jiarong

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

  4. Huang, Min

    1. Novel Clinical Biomarkers for Drug-Induced Liver Injury
      Youhao Chen, Shaoxing Guan, Yanping Guan, Siyuan Tang, Yanying Zhou, Xueding Wang, Huichang Bi and Min Huang
      Drug Metabolism and Disposition May 2022, 50 (5) 671-684; DOI: https://doi.org/10.1124/dmd.121.000732
    2. Nuclear Receptor-Mediated Hepatomegaly and Liver Regeneration: An Update
      Pengfei Zhao, Shicheng Fan, Yue Gao, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2022, 50 (5) 636-645; DOI: https://doi.org/10.1124/dmd.121.000454

I

  1. Izumi, Saki

    1. Experimental and Modeling Evidence Supporting the Trans-Inhibition Mechanism for Preincubation Time-Dependent, Long-Lasting Inhibition of Organic Anion Transporting Polypeptide 1B1 by Cyclosporine A
      Saki Izumi, Yoshitane Nozaki, Wooin Lee and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2022, 50 (5) 541-551; DOI: https://doi.org/10.1124/dmd.121.000783

K

  1. Kadar, Eugene P.

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

  2. Kalgutkar, Amit S.

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

  3. Kimoto, Emi

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

  4. Klammers, Florian

    1. Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Florian Klammers, Andreas Goetschi, Aynur Ekiciler, Isabelle Walter, Neil Parrott, Stephen Fowler and Kenichi Umehara
      Drug Metabolism and Disposition May 2022, 50 (5) 566-575; DOI: https://doi.org/10.1124/dmd.121.000765

  5. Koh, Siew Kwan

    1. Direct and Sequential Bioactivation of Pemigatinib to Reactive Iminium Ion Intermediates Culminates in Mechanism-Based Inactivation of Cytochrome P450 3A
      Lloyd Wei Tat Tang, Wan Wei, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Hao Fan and Eric Chun Yong Chan
      Drug Metabolism and Disposition May 2022, 50 (5) 529-540; DOI: https://doi.org/10.1124/dmd.121.000804

L

  1. Ladumor, Mayur K.

    1. Open Access
      Estimation of Fetal-to-Maternal Unbound Steady-State Plasma Concentration Ratio of P-Glycoprotein and/or Breast Cancer Resistance Protein Substrate Drugs Using a Maternal-Fetal Physiologically Based Pharmacokinetic Model
      Jinfu Peng, Mayur K. Ladumor and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2022, 50 (5) 613-623; DOI: https://doi.org/10.1124/dmd.121.000733
    2. Predicting Regional Respiratory Tissue and Systemic Concentrations of Orally Inhaled Drugs through a Novel PBPK Model
      Mayur K. Ladumor and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2022, 50 (5) 519-528; DOI: https://doi.org/10.1124/dmd.121.000789

  2. Lai, Yurong

    1. Special Section On Drug Metabolism in Liver Injury and Repair—Editorial
      Xiao-bo Zhong and Yurong Lai
      Drug Metabolism and Disposition May 2022, 50 (5) 634-635; DOI: https://doi.org/10.1124/dmd.122.000869

  3. Lee, Wooin

    1. Experimental and Modeling Evidence Supporting the Trans-Inhibition Mechanism for Preincubation Time-Dependent, Long-Lasting Inhibition of Organic Anion Transporting Polypeptide 1B1 by Cyclosporine A
      Saki Izumi, Yoshitane Nozaki, Wooin Lee and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2022, 50 (5) 541-551; DOI: https://doi.org/10.1124/dmd.121.000783

  4. Liang, Alina

    1. Roles of Cofactors in Drug-Induced Liver Injury: Drug Metabolism and Beyond
      Ruizhi Gu, Alina Liang, Grace Liao, Isabelle To, Amina Shehu and Xiaochao Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 646-654; DOI: https://doi.org/10.1124/dmd.121.000457

  5. Liang, Jingru

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

  6. Liao, Grace

    1. Roles of Cofactors in Drug-Induced Liver Injury: Drug Metabolism and Beyond
      Ruizhi Gu, Alina Liang, Grace Liao, Isabelle To, Amina Shehu and Xiaochao Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 646-654; DOI: https://doi.org/10.1124/dmd.121.000457

  7. Lin, Jian

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

  8. Lin, Yanke

    1. E4BP4 Regulates Hepatic Solute Carrier Family 2 Member 9 and Uric Acid Disposition in Mice
      Zhigang Wang, Lu Gao, Shujing Ren, Guanghui Sun, Yanke Lin, Shuai Wang and Baojian Wu
      Drug Metabolism and Disposition May 2022, 50 (5) 591-599; DOI: https://doi.org/10.1124/dmd.121.000790

  9. Liu, Bei

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

  10. Liu, Ye

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

M

  1. Ma, Guo

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

  2. Ma, Xiaochao

    1. Alterations of Cytochrome P450–Mediated Drug Metabolism during Liver Repair and Regeneration after Acetaminophen-Induced Liver Injury in Mice
      Yifan Bao, Mi Phan, Junjie Zhu, Xiaochao Ma, José E. Manautou and Xiao-bo Zhong
      Drug Metabolism and Disposition May 2022, 50 (5) 694-703; DOI: https://doi.org/10.1124/dmd.121.000459
    2. Roles of Cofactors in Drug-Induced Liver Injury: Drug Metabolism and Beyond
      Ruizhi Gu, Alina Liang, Grace Liao, Isabelle To, Amina Shehu and Xiaochao Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 646-654; DOI: https://doi.org/10.1124/dmd.121.000457

  3. Manautou, José E.

    1. Alterations of Cytochrome P450–Mediated Drug Metabolism during Liver Repair and Regeneration after Acetaminophen-Induced Liver Injury in Mice
      Yifan Bao, Mi Phan, Junjie Zhu, Xiaochao Ma, José E. Manautou and Xiao-bo Zhong
      Drug Metabolism and Disposition May 2022, 50 (5) 694-703; DOI: https://doi.org/10.1124/dmd.121.000459

N

  1. Nakajima, Miki

    1. Adenosine-to-Inosine RNA Editing and N6-Methyladenosine Modification Modulating Expression of Drug Metabolizing Enzymes
      Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition May 2022, 50 (5) 624-633; DOI: https://doi.org/10.1124/dmd.121.000390

  2. Nakano, Masataka

    1. Adenosine-to-Inosine RNA Editing and N6-Methyladenosine Modification Modulating Expression of Drug Metabolizing Enzymes
      Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition May 2022, 50 (5) 624-633; DOI: https://doi.org/10.1124/dmd.121.000390

  3. Novak, Jonathan J.

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

  4. Nozaki, Yoshitane

    1. Experimental and Modeling Evidence Supporting the Trans-Inhibition Mechanism for Preincubation Time-Dependent, Long-Lasting Inhibition of Organic Anion Transporting Polypeptide 1B1 by Cyclosporine A
      Saki Izumi, Yoshitane Nozaki, Wooin Lee and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2022, 50 (5) 541-551; DOI: https://doi.org/10.1124/dmd.121.000783

O

  1. Obach, R. Scott

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

  2. Oh, Eugene

    1. Open Access
      Determination of Acyl-, O-, and N-Glucuronide Using Chemical Derivatization Coupled with Liquid Chromatography–High-Resolution Mass Spectrometry
      Yukuang Guo, Abhi Shah, Eugene Oh, Swapan K. Chowdhury and Xiaochun Zhu
      Drug Metabolism and Disposition May 2022, 50 (5) 716-724; DOI: https://doi.org/10.1124/dmd.122.000832

P

  1. Parrott, Neil

    1. Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Florian Klammers, Andreas Goetschi, Aynur Ekiciler, Isabelle Walter, Neil Parrott, Stephen Fowler and Kenichi Umehara
      Drug Metabolism and Disposition May 2022, 50 (5) 566-575; DOI: https://doi.org/10.1124/dmd.121.000765

  2. Patel, Nandini C.

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

  3. Peng, Jinfu

    1. Open Access
      Estimation of Fetal-to-Maternal Unbound Steady-State Plasma Concentration Ratio of P-Glycoprotein and/or Breast Cancer Resistance Protein Substrate Drugs Using a Maternal-Fetal Physiologically Based Pharmacokinetic Model
      Jinfu Peng, Mayur K. Ladumor and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2022, 50 (5) 613-623; DOI: https://doi.org/10.1124/dmd.121.000733

  4. Peng, Ying

    1. Metabolic Activation and Hepatotoxicity of Furan-Containing Compounds
      Min Tian, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition May 2022, 50 (5) 655-670; DOI: https://doi.org/10.1124/dmd.121.000458

  5. Phan, Mi

    1. Alterations of Cytochrome P450–Mediated Drug Metabolism during Liver Repair and Regeneration after Acetaminophen-Induced Liver Injury in Mice
      Yifan Bao, Mi Phan, Junjie Zhu, Xiaochao Ma, José E. Manautou and Xiao-bo Zhong
      Drug Metabolism and Disposition May 2022, 50 (5) 694-703; DOI: https://doi.org/10.1124/dmd.121.000459

R

  1. Ren, Shujing

    1. E4BP4 Regulates Hepatic Solute Carrier Family 2 Member 9 and Uric Acid Disposition in Mice
      Zhigang Wang, Lu Gao, Shujing Ren, Guanghui Sun, Yanke Lin, Shuai Wang and Baojian Wu
      Drug Metabolism and Disposition May 2022, 50 (5) 591-599; DOI: https://doi.org/10.1124/dmd.121.000790

  2. Rock, Brooke M.

    1. Absorption, Distribution, Metabolism, and Excretion of [14C]-Sotorasib in Rats and Dogs: Interspecies Differences in Absorption, Protein Conjugation and Metabolism
      Upendra P. Dahal, Brooke M. Rock, John Rodgers, Xiaomeng Shen, Zhe Wang and Jan L. Wahlstrom
      Drug Metabolism and Disposition May 2022, 50 (5) 600-612; DOI: https://doi.org/10.1124/dmd.121.000798

  3. Rodgers, John

    1. Absorption, Distribution, Metabolism, and Excretion of [14C]-Sotorasib in Rats and Dogs: Interspecies Differences in Absorption, Protein Conjugation and Metabolism
      Upendra P. Dahal, Brooke M. Rock, John Rodgers, Xiaomeng Shen, Zhe Wang and Jan L. Wahlstrom
      Drug Metabolism and Disposition May 2022, 50 (5) 600-612; DOI: https://doi.org/10.1124/dmd.121.000798

S

  1. Shah, Abhi

    1. Open Access
      Determination of Acyl-, O-, and N-Glucuronide Using Chemical Derivatization Coupled with Liquid Chromatography–High-Resolution Mass Spectrometry
      Yukuang Guo, Abhi Shah, Eugene Oh, Swapan K. Chowdhury and Xiaochun Zhu
      Drug Metabolism and Disposition May 2022, 50 (5) 716-724; DOI: https://doi.org/10.1124/dmd.122.000832

  2. Shehu, Amina

    1. Roles of Cofactors in Drug-Induced Liver Injury: Drug Metabolism and Beyond
      Ruizhi Gu, Alina Liang, Grace Liao, Isabelle To, Amina Shehu and Xiaochao Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 646-654; DOI: https://doi.org/10.1124/dmd.121.000457

  3. Shen, Xiaomeng

    1. Absorption, Distribution, Metabolism, and Excretion of [14C]-Sotorasib in Rats and Dogs: Interspecies Differences in Absorption, Protein Conjugation and Metabolism
      Upendra P. Dahal, Brooke M. Rock, John Rodgers, Xiaomeng Shen, Zhe Wang and Jan L. Wahlstrom
      Drug Metabolism and Disposition May 2022, 50 (5) 600-612; DOI: https://doi.org/10.1124/dmd.121.000798

  4. Singh, Ravi Shankar P.

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

  5. Sugiyama, Yuichi

    1. Experimental and Modeling Evidence Supporting the Trans-Inhibition Mechanism for Preincubation Time-Dependent, Long-Lasting Inhibition of Organic Anion Transporting Polypeptide 1B1 by Cyclosporine A
      Saki Izumi, Yoshitane Nozaki, Wooin Lee and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2022, 50 (5) 541-551; DOI: https://doi.org/10.1124/dmd.121.000783

  6. Sun, Guanghui

    1. E4BP4 Regulates Hepatic Solute Carrier Family 2 Member 9 and Uric Acid Disposition in Mice
      Zhigang Wang, Lu Gao, Shujing Ren, Guanghui Sun, Yanke Lin, Shuai Wang and Baojian Wu
      Drug Metabolism and Disposition May 2022, 50 (5) 591-599; DOI: https://doi.org/10.1124/dmd.121.000790

T

  1. Tang, Lloyd Wei Tat

    1. Direct and Sequential Bioactivation of Pemigatinib to Reactive Iminium Ion Intermediates Culminates in Mechanism-Based Inactivation of Cytochrome P450 3A
      Lloyd Wei Tat Tang, Wan Wei, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Hao Fan and Eric Chun Yong Chan
      Drug Metabolism and Disposition May 2022, 50 (5) 529-540; DOI: https://doi.org/10.1124/dmd.121.000804

  2. Tang, Siyuan

    1. Novel Clinical Biomarkers for Drug-Induced Liver Injury
      Youhao Chen, Shaoxing Guan, Yanping Guan, Siyuan Tang, Yanying Zhou, Xueding Wang, Huichang Bi and Min Huang
      Drug Metabolism and Disposition May 2022, 50 (5) 671-684; DOI: https://doi.org/10.1124/dmd.121.000732

  3. Tian, Min

    1. Metabolic Activation and Hepatotoxicity of Furan-Containing Compounds
      Min Tian, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition May 2022, 50 (5) 655-670; DOI: https://doi.org/10.1124/dmd.121.000458

  4. To, Isabelle

    1. Roles of Cofactors in Drug-Induced Liver Injury: Drug Metabolism and Beyond
      Ruizhi Gu, Alina Liang, Grace Liao, Isabelle To, Amina Shehu and Xiaochao Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 646-654; DOI: https://doi.org/10.1124/dmd.121.000457

U

  1. Umehara, Kenichi

    1. Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Florian Klammers, Andreas Goetschi, Aynur Ekiciler, Isabelle Walter, Neil Parrott, Stephen Fowler and Kenichi Umehara
      Drug Metabolism and Disposition May 2022, 50 (5) 566-575; DOI: https://doi.org/10.1124/dmd.121.000765

  2. Unadkat, Jashvant D.

    1. Open Access
      Estimation of Fetal-to-Maternal Unbound Steady-State Plasma Concentration Ratio of P-Glycoprotein and/or Breast Cancer Resistance Protein Substrate Drugs Using a Maternal-Fetal Physiologically Based Pharmacokinetic Model
      Jinfu Peng, Mayur K. Ladumor and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2022, 50 (5) 613-623; DOI: https://doi.org/10.1124/dmd.121.000733
    2. Predicting Regional Respiratory Tissue and Systemic Concentrations of Orally Inhaled Drugs through a Novel PBPK Model
      Mayur K. Ladumor and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2022, 50 (5) 519-528; DOI: https://doi.org/10.1124/dmd.121.000789

V

  1. Verma, Ravi Kumar

    1. Direct and Sequential Bioactivation of Pemigatinib to Reactive Iminium Ion Intermediates Culminates in Mechanism-Based Inactivation of Cytochrome P450 3A
      Lloyd Wei Tat Tang, Wan Wei, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Hao Fan and Eric Chun Yong Chan
      Drug Metabolism and Disposition May 2022, 50 (5) 529-540; DOI: https://doi.org/10.1124/dmd.121.000804

W

  1. Wahlstrom, Jan L.

    1. Absorption, Distribution, Metabolism, and Excretion of [14C]-Sotorasib in Rats and Dogs: Interspecies Differences in Absorption, Protein Conjugation and Metabolism
      Upendra P. Dahal, Brooke M. Rock, John Rodgers, Xiaomeng Shen, Zhe Wang and Jan L. Wahlstrom
      Drug Metabolism and Disposition May 2022, 50 (5) 600-612; DOI: https://doi.org/10.1124/dmd.121.000798

  2. Walker, Gregory S.

    1. Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
      Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar
      Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801

  3. Walter, Isabelle

    1. Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes
      Florian Klammers, Andreas Goetschi, Aynur Ekiciler, Isabelle Walter, Neil Parrott, Stephen Fowler and Kenichi Umehara
      Drug Metabolism and Disposition May 2022, 50 (5) 566-575; DOI: https://doi.org/10.1124/dmd.121.000765

  4. Wang, Pei

    1. Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells
      Xiaofei Wang, Yihang Yu, Pei Wang, Kun Yang, Yiting Wang, Liang Yan, Xiao-bo Zhong and Lirong Zhang
      Drug Metabolism and Disposition May 2022, 50 (5) 704-715; DOI: https://doi.org/10.1124/dmd.121.000693

  5. Wang, Ping

    1. Withaferin A in the Treatment of Liver Diseases: Progress and Pharmacokinetic Insights
      Yangliu Xia, Mingrui Yan, Ping Wang, Keisuke Hamada, Nana Yan, Haiping Hao, Frank J. Gonzalez and Tingting Yan
      Drug Metabolism and Disposition May 2022, 50 (5) 685-693; DOI: https://doi.org/10.1124/dmd.121.000455

  6. Wang, Shuai

    1. E4BP4 Regulates Hepatic Solute Carrier Family 2 Member 9 and Uric Acid Disposition in Mice
      Zhigang Wang, Lu Gao, Shujing Ren, Guanghui Sun, Yanke Lin, Shuai Wang and Baojian Wu
      Drug Metabolism and Disposition May 2022, 50 (5) 591-599; DOI: https://doi.org/10.1124/dmd.121.000790

  7. Wang, Xiaofei

    1. Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells
      Xiaofei Wang, Yihang Yu, Pei Wang, Kun Yang, Yiting Wang, Liang Yan, Xiao-bo Zhong and Lirong Zhang
      Drug Metabolism and Disposition May 2022, 50 (5) 704-715; DOI: https://doi.org/10.1124/dmd.121.000693

  8. Wang, Xueding

    1. Novel Clinical Biomarkers for Drug-Induced Liver Injury
      Youhao Chen, Shaoxing Guan, Yanping Guan, Siyuan Tang, Yanying Zhou, Xueding Wang, Huichang Bi and Min Huang
      Drug Metabolism and Disposition May 2022, 50 (5) 671-684; DOI: https://doi.org/10.1124/dmd.121.000732

  9. Wang, Yiting

    1. Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells
      Xiaofei Wang, Yihang Yu, Pei Wang, Kun Yang, Yiting Wang, Liang Yan, Xiao-bo Zhong and Lirong Zhang
      Drug Metabolism and Disposition May 2022, 50 (5) 704-715; DOI: https://doi.org/10.1124/dmd.121.000693

  10. Wang, Zhe

    1. Absorption, Distribution, Metabolism, and Excretion of [14C]-Sotorasib in Rats and Dogs: Interspecies Differences in Absorption, Protein Conjugation and Metabolism
      Upendra P. Dahal, Brooke M. Rock, John Rodgers, Xiaomeng Shen, Zhe Wang and Jan L. Wahlstrom
      Drug Metabolism and Disposition May 2022, 50 (5) 600-612; DOI: https://doi.org/10.1124/dmd.121.000798

  11. Wang, Zhigang

    1. E4BP4 Regulates Hepatic Solute Carrier Family 2 Member 9 and Uric Acid Disposition in Mice
      Zhigang Wang, Lu Gao, Shujing Ren, Guanghui Sun, Yanke Lin, Shuai Wang and Baojian Wu
      Drug Metabolism and Disposition May 2022, 50 (5) 591-599; DOI: https://doi.org/10.1124/dmd.121.000790

  12. Wei, Wan

    1. Direct and Sequential Bioactivation of Pemigatinib to Reactive Iminium Ion Intermediates Culminates in Mechanism-Based Inactivation of Cytochrome P450 3A
      Lloyd Wei Tat Tang, Wan Wei, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Hao Fan and Eric Chun Yong Chan
      Drug Metabolism and Disposition May 2022, 50 (5) 529-540; DOI: https://doi.org/10.1124/dmd.121.000804

  13. Wu, Baojian

    1. E4BP4 Regulates Hepatic Solute Carrier Family 2 Member 9 and Uric Acid Disposition in Mice
      Zhigang Wang, Lu Gao, Shujing Ren, Guanghui Sun, Yanke Lin, Shuai Wang and Baojian Wu
      Drug Metabolism and Disposition May 2022, 50 (5) 591-599; DOI: https://doi.org/10.1124/dmd.121.000790

  14. Wu, Xubo

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

X

  1. Xia, Yangliu

    1. Withaferin A in the Treatment of Liver Diseases: Progress and Pharmacokinetic Insights
      Yangliu Xia, Mingrui Yan, Ping Wang, Keisuke Hamada, Nana Yan, Haiping Hao, Frank J. Gonzalez and Tingting Yan
      Drug Metabolism and Disposition May 2022, 50 (5) 685-693; DOI: https://doi.org/10.1124/dmd.121.000455

Y

  1. Yan, Liang

    1. Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells
      Xiaofei Wang, Yihang Yu, Pei Wang, Kun Yang, Yiting Wang, Liang Yan, Xiao-bo Zhong and Lirong Zhang
      Drug Metabolism and Disposition May 2022, 50 (5) 704-715; DOI: https://doi.org/10.1124/dmd.121.000693

  2. Yan, Mingrui

    1. Withaferin A in the Treatment of Liver Diseases: Progress and Pharmacokinetic Insights
      Yangliu Xia, Mingrui Yan, Ping Wang, Keisuke Hamada, Nana Yan, Haiping Hao, Frank J. Gonzalez and Tingting Yan
      Drug Metabolism and Disposition May 2022, 50 (5) 685-693; DOI: https://doi.org/10.1124/dmd.121.000455

  3. Yan, Nana

    1. Withaferin A in the Treatment of Liver Diseases: Progress and Pharmacokinetic Insights
      Yangliu Xia, Mingrui Yan, Ping Wang, Keisuke Hamada, Nana Yan, Haiping Hao, Frank J. Gonzalez and Tingting Yan
      Drug Metabolism and Disposition May 2022, 50 (5) 685-693; DOI: https://doi.org/10.1124/dmd.121.000455

  4. Yan, Tingting

    1. Withaferin A in the Treatment of Liver Diseases: Progress and Pharmacokinetic Insights
      Yangliu Xia, Mingrui Yan, Ping Wang, Keisuke Hamada, Nana Yan, Haiping Hao, Frank J. Gonzalez and Tingting Yan
      Drug Metabolism and Disposition May 2022, 50 (5) 685-693; DOI: https://doi.org/10.1124/dmd.121.000455

  5. Yang, Kun

    1. Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells
      Xiaofei Wang, Yihang Yu, Pei Wang, Kun Yang, Yiting Wang, Liang Yan, Xiao-bo Zhong and Lirong Zhang
      Drug Metabolism and Disposition May 2022, 50 (5) 704-715; DOI: https://doi.org/10.1124/dmd.121.000693

  6. Yang, Ping

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

  7. Yang, Qing

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

  8. Yang, Xiaolei

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

  9. Yu, Yihang

    1. Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells
      Xiaofei Wang, Yihang Yu, Pei Wang, Kun Yang, Yiting Wang, Liang Yan, Xiao-bo Zhong and Lirong Zhang
      Drug Metabolism and Disposition May 2022, 50 (5) 704-715; DOI: https://doi.org/10.1124/dmd.121.000693

Z

  1. Zhang, Lirong

    1. Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells
      Xiaofei Wang, Yihang Yu, Pei Wang, Kun Yang, Yiting Wang, Liang Yan, Xiao-bo Zhong and Lirong Zhang
      Drug Metabolism and Disposition May 2022, 50 (5) 704-715; DOI: https://doi.org/10.1124/dmd.121.000693

  2. Zhang, Ying

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

  3. Zhao, Pengfei

    1. Nuclear Receptor-Mediated Hepatomegaly and Liver Regeneration: An Update
      Pengfei Zhao, Shicheng Fan, Yue Gao, Min Huang and Huichang Bi
      Drug Metabolism and Disposition May 2022, 50 (5) 636-645; DOI: https://doi.org/10.1124/dmd.121.000454

  4. Zheng, Jiang

    1. Metabolic Activation and Hepatotoxicity of Furan-Containing Compounds
      Min Tian, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition May 2022, 50 (5) 655-670; DOI: https://doi.org/10.1124/dmd.121.000458

  5. Zhong, Xiao-bo

    1. Alterations of Cytochrome P450–Mediated Drug Metabolism during Liver Repair and Regeneration after Acetaminophen-Induced Liver Injury in Mice
      Yifan Bao, Mi Phan, Junjie Zhu, Xiaochao Ma, José E. Manautou and Xiao-bo Zhong
      Drug Metabolism and Disposition May 2022, 50 (5) 694-703; DOI: https://doi.org/10.1124/dmd.121.000459
    2. Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells
      Xiaofei Wang, Yihang Yu, Pei Wang, Kun Yang, Yiting Wang, Liang Yan, Xiao-bo Zhong and Lirong Zhang
      Drug Metabolism and Disposition May 2022, 50 (5) 704-715; DOI: https://doi.org/10.1124/dmd.121.000693
    3. Special Section On Drug Metabolism in Liver Injury and Repair—Editorial
      Xiao-bo Zhong and Yurong Lai
      Drug Metabolism and Disposition May 2022, 50 (5) 634-635; DOI: https://doi.org/10.1124/dmd.122.000869

  6. Zhou, Lei

    1. Direct and Sequential Bioactivation of Pemigatinib to Reactive Iminium Ion Intermediates Culminates in Mechanism-Based Inactivation of Cytochrome P450 3A
      Lloyd Wei Tat Tang, Wan Wei, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Hao Fan and Eric Chun Yong Chan
      Drug Metabolism and Disposition May 2022, 50 (5) 529-540; DOI: https://doi.org/10.1124/dmd.121.000804

  7. Zhou, Yanying

    1. Novel Clinical Biomarkers for Drug-Induced Liver Injury
      Youhao Chen, Shaoxing Guan, Yanping Guan, Siyuan Tang, Yanying Zhou, Xueding Wang, Huichang Bi and Min Huang
      Drug Metabolism and Disposition May 2022, 50 (5) 671-684; DOI: https://doi.org/10.1124/dmd.121.000732

  8. Zhu, Guanghao

    1. Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice
      Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai and Guo Ma
      Drug Metabolism and Disposition May 2022, 50 (5) 552-565; DOI: https://doi.org/10.1124/dmd.121.000714

  9. Zhu, Junjie

    1. Alterations of Cytochrome P450–Mediated Drug Metabolism during Liver Repair and Regeneration after Acetaminophen-Induced Liver Injury in Mice
      Yifan Bao, Mi Phan, Junjie Zhu, Xiaochao Ma, José E. Manautou and Xiao-bo Zhong
      Drug Metabolism and Disposition May 2022, 50 (5) 694-703; DOI: https://doi.org/10.1124/dmd.121.000459

  10. Zhu, Xiaochun

    1. Open Access
      Determination of Acyl-, O-, and N-Glucuronide Using Chemical Derivatization Coupled with Liquid Chromatography–High-Resolution Mass Spectrometry
      Yukuang Guo, Abhi Shah, Eugene Oh, Swapan K. Chowdhury and Xiaochun Zhu
      Drug Metabolism and Disposition May 2022, 50 (5) 716-724; DOI: https://doi.org/10.1124/dmd.122.000832
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