Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester, Manchester, United Kingdom (J.B., Z.M.A.-M., N.C., A.-M.V., A.T., S.A., A.R.-H., B.A.) Simcyp Division, Certara, Sheffield, United Kingdom (A.R.-H.) and Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, the University of Rhode Island, Kingston, Rhode Island (B.A.)

Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester, Manchester, United Kingdom (J.B., Z.M.A.-M., N.C., A.-M.V., A.T., S.A., A.R.-H., B.A.) Simcyp Division, Certara, Sheffield, United Kingdom (A.R.-H.) and Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, the University of Rhode Island, Kingston, Rhode Island (B.A.)

Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester, Manchester, United Kingdom (J.B., Z.M.A.-M., N.C., A.-M.V., A.T., S.A., A.R.-H., B.A.) Simcyp Division, Certara, Sheffield, United Kingdom (A.R.-H.) and Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, the University of Rhode Island, Kingston, Rhode Island (B.A.)

Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester, Manchester, United Kingdom (J.B., Z.M.A.-M., N.C., A.-M.V., A.T., S.A., A.R.-H., B.A.) Simcyp Division, Certara, Sheffield, United Kingdom (A.R.-H.) and Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, the University of Rhode Island, Kingston, Rhode Island (B.A.)

Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester, Manchester, United Kingdom (J.B., Z.M.A.-M., N.C., A.-M.V., A.T., S.A., A.R.-H., B.A.) Simcyp Division, Certara, Sheffield, United Kingdom (A.R.-H.) and Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, the University of Rhode Island, Kingston, Rhode Island (B.A.)

Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester, Manchester, United Kingdom (J.B., Z.M.A.-M., N.C., A.-M.V., A.T., S.A., A.R.-H., B.A.) Simcyp Division, Certara, Sheffield, United Kingdom (A.R.-H.) and Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, the University of Rhode Island, Kingston, Rhode Island (B.A.)

Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester, Manchester, United Kingdom (J.B., Z.M.A.-M., N.C., A.-M.V., A.T., S.A., A.R.-H., B.A.) Simcyp Division, Certara, Sheffield, United Kingdom (A.R.-H.) and Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, the University of Rhode Island, Kingston, Rhode Island (B.A.)

Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester, Manchester, United Kingdom (J.B., Z.M.A.-M., N.C., A.-M.V., A.T., S.A., A.R.-H., B.A.) Simcyp Division, Certara, Sheffield, United Kingdom (A.R.-H.) and Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, the University of Rhode Island, Kingston, Rhode Island (B.A.)