Index by author
September 01, 2022; Volume 50,Issue 9
B
Balesano, Amanda
- You have accessDefining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting ApproachAngela C. Doran, Woodrow Burchett, Connor Landers, Gabrielle M. Gualtieri, Amanda Balesano, Heather Eng, Alyssa L Dantonio, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1259-1271; DOI: https://doi.org/10.1124/dmd.122.000884
- You have accessAn Improved Method for Cytochrome P450 Reaction Phenotyping Using a Sequential Qualitative-Then-Quantitative ApproachAngela C. Doran, Alyssa L. Dantonio, Gabrielle M. Gualtieri, Amanda Balesano, Connor Landers, Woodrow Burchett, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1272-1286; DOI: https://doi.org/10.1124/dmd.122.000883
Bessire, Andrew J.
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
Bi, Yi-an
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
Brundage, Richard C.
- You have accessPharmacokinetic Modeling of Warfarin ІI – Model-Based Analysis of Warfarin Metabolites after Warfarin Administered Either Alone or Together with Fluconazole or RifampinShen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. TracyDrug Metabolism and Disposition September 2022, 50 (9) 1302-1311; DOI: https://doi.org/10.1124/dmd.122.000877
- You have accessPharmacokinetic Modeling of Warfarin І – Model-Based Analysis of Warfarin Enantiomers with a Target Mediated Drug Disposition Model Reveals CYP2C9 Genotype-Dependent Drug-Drug Interactions of S-WarfarinShen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. TracyDrug Metabolism and Disposition September 2022, 50 (9) 1287-1301; DOI: https://doi.org/10.1124/dmd.122.000876
Burchett, Woodrow
- You have accessDefining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting ApproachAngela C. Doran, Woodrow Burchett, Connor Landers, Gabrielle M. Gualtieri, Amanda Balesano, Heather Eng, Alyssa L Dantonio, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1259-1271; DOI: https://doi.org/10.1124/dmd.122.000884
- You have accessAn Improved Method for Cytochrome P450 Reaction Phenotyping Using a Sequential Qualitative-Then-Quantitative ApproachAngela C. Doran, Alyssa L. Dantonio, Gabrielle M. Gualtieri, Amanda Balesano, Connor Landers, Woodrow Burchett, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1272-1286; DOI: https://doi.org/10.1124/dmd.122.000883
C
Cerny, Mathew A.
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
Chen, Ligong
- Open AccessAmino Acid Solute Carrier Transporters in Inflammation and AutoimmunityLinlin Sheng, Qi Luo and Ligong ChenDrug Metabolism and Disposition September 2022, 50 (9) 1228-1237; DOI: https://doi.org/10.1124/dmd.121.000705
Chen, Xue
- You have accessAntibiotics-Induced Disruption of Gut Microbiota Increases Systemic Exposure of Clopidogrel Active Metabolite in Type 2 Diabetic RatsXue Chen, Yingrui Liu, Hongwei Yao, Wenfang Song, Yu Song, Jingkai Gu and Yingjie GuoDrug Metabolism and Disposition September 2022, 50 (9) 1142-1150; DOI: https://doi.org/10.1124/dmd.122.000906
Cheng, Shen
- You have accessPharmacokinetic Modeling of Warfarin ІI – Model-Based Analysis of Warfarin Metabolites after Warfarin Administered Either Alone or Together with Fluconazole or RifampinShen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. TracyDrug Metabolism and Disposition September 2022, 50 (9) 1302-1311; DOI: https://doi.org/10.1124/dmd.122.000877
- You have accessPharmacokinetic Modeling of Warfarin І – Model-Based Analysis of Warfarin Enantiomers with a Target Mediated Drug Disposition Model Reveals CYP2C9 Genotype-Dependent Drug-Drug Interactions of S-WarfarinShen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. TracyDrug Metabolism and Disposition September 2022, 50 (9) 1287-1301; DOI: https://doi.org/10.1124/dmd.122.000876
D
Dantonio, Alyssa L
- You have accessDefining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting ApproachAngela C. Doran, Woodrow Burchett, Connor Landers, Gabrielle M. Gualtieri, Amanda Balesano, Heather Eng, Alyssa L Dantonio, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1259-1271; DOI: https://doi.org/10.1124/dmd.122.000884
Dantonio, Alyssa L.
- You have accessAn Improved Method for Cytochrome P450 Reaction Phenotyping Using a Sequential Qualitative-Then-Quantitative ApproachAngela C. Doran, Alyssa L. Dantonio, Gabrielle M. Gualtieri, Amanda Balesano, Connor Landers, Woodrow Burchett, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1272-1286; DOI: https://doi.org/10.1124/dmd.122.000883
Di, Li
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
Doran, Angela C.
- You have accessDefining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting ApproachAngela C. Doran, Woodrow Burchett, Connor Landers, Gabrielle M. Gualtieri, Amanda Balesano, Heather Eng, Alyssa L Dantonio, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1259-1271; DOI: https://doi.org/10.1124/dmd.122.000884
- You have accessAn Improved Method for Cytochrome P450 Reaction Phenotyping Using a Sequential Qualitative-Then-Quantitative ApproachAngela C. Doran, Alyssa L. Dantonio, Gabrielle M. Gualtieri, Amanda Balesano, Connor Landers, Woodrow Burchett, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1272-1286; DOI: https://doi.org/10.1124/dmd.122.000883
E
Eades, William
- You have accessThe COVID-19 Oral Drug Molnupiravir Is a CES2 Substrate: Potential Drug-Drug Interactions and Impact of CES2 Genetic Polymorphism In VitroYue Shen, William Eades, William Liu and Bingfang YanDrug Metabolism and Disposition September 2022, 50 (9) 1151-1160; DOI: https://doi.org/10.1124/dmd.122.000918
Eng, Heather
- You have accessDefining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting ApproachAngela C. Doran, Woodrow Burchett, Connor Landers, Gabrielle M. Gualtieri, Amanda Balesano, Heather Eng, Alyssa L Dantonio, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1259-1271; DOI: https://doi.org/10.1124/dmd.122.000884
F
Flora, Darcy R.
- You have accessPharmacokinetic Modeling of Warfarin ІI – Model-Based Analysis of Warfarin Metabolites after Warfarin Administered Either Alone or Together with Fluconazole or RifampinShen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. TracyDrug Metabolism and Disposition September 2022, 50 (9) 1302-1311; DOI: https://doi.org/10.1124/dmd.122.000877
- You have accessPharmacokinetic Modeling of Warfarin І – Model-Based Analysis of Warfarin Enantiomers with a Target Mediated Drug Disposition Model Reveals CYP2C9 Genotype-Dependent Drug-Drug Interactions of S-WarfarinShen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. TracyDrug Metabolism and Disposition September 2022, 50 (9) 1287-1301; DOI: https://doi.org/10.1124/dmd.122.000876
Fonseca, Kari R.
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
Furugen, Ayako
- You have accessThe rs35217482 (T755I) Single-Nucleotide Polymorphism in Aldehyde Oxidase-1 Attenuates Protein Dimer Formation and Reduces the Rates of Phthalazine MetabolismHinata Ueda, Katsuya Narumi, Ayako Furugen, Yoshitaka Saito and Masaki KobayashiDrug Metabolism and Disposition September 2022, 50 (9) 1126-1131; DOI: https://doi.org/10.1124/dmd.122.000902
G
Giacomini, Kathleen M.
- You have accessEmerging Roles of the Human Solute Carrier 22 FamilySook Wah Yee and Kathleen M. GiacominiDrug Metabolism and Disposition September 2022, 50 (9) 1193-1210; DOI: https://doi.org/10.1124/dmd.121.000702
Goosen, Theunis C.
- You have accessDefining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting ApproachAngela C. Doran, Woodrow Burchett, Connor Landers, Gabrielle M. Gualtieri, Amanda Balesano, Heather Eng, Alyssa L Dantonio, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1259-1271; DOI: https://doi.org/10.1124/dmd.122.000884
- You have accessAn Improved Method for Cytochrome P450 Reaction Phenotyping Using a Sequential Qualitative-Then-Quantitative ApproachAngela C. Doran, Alyssa L. Dantonio, Gabrielle M. Gualtieri, Amanda Balesano, Connor Landers, Woodrow Burchett, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1272-1286; DOI: https://doi.org/10.1124/dmd.122.000883
Gu, Jingkai
- You have accessAntibiotics-Induced Disruption of Gut Microbiota Increases Systemic Exposure of Clopidogrel Active Metabolite in Type 2 Diabetic RatsXue Chen, Yingrui Liu, Hongwei Yao, Wenfang Song, Yu Song, Jingkai Gu and Yingjie GuoDrug Metabolism and Disposition September 2022, 50 (9) 1142-1150; DOI: https://doi.org/10.1124/dmd.122.000906
Gualtieri, Gabrielle M.
- You have accessDefining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting ApproachAngela C. Doran, Woodrow Burchett, Connor Landers, Gabrielle M. Gualtieri, Amanda Balesano, Heather Eng, Alyssa L Dantonio, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1259-1271; DOI: https://doi.org/10.1124/dmd.122.000884
- You have accessAn Improved Method for Cytochrome P450 Reaction Phenotyping Using a Sequential Qualitative-Then-Quantitative ApproachAngela C. Doran, Alyssa L. Dantonio, Gabrielle M. Gualtieri, Amanda Balesano, Connor Landers, Woodrow Burchett, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1272-1286; DOI: https://doi.org/10.1124/dmd.122.000883
Guo, Yingjie
- You have accessAntibiotics-Induced Disruption of Gut Microbiota Increases Systemic Exposure of Clopidogrel Active Metabolite in Type 2 Diabetic RatsXue Chen, Yingrui Liu, Hongwei Yao, Wenfang Song, Yu Song, Jingkai Gu and Yingjie GuoDrug Metabolism and Disposition September 2022, 50 (9) 1142-1150; DOI: https://doi.org/10.1124/dmd.122.000906
H
Hop, Cornelis E.C.A.
- You have accessPhysiologically Based Pharmacokinetic Models Can Be Used to Predict the Unique Nonlinear Absorption Profiles of VismodegibLouis Lin, Matthew R. Wright, Cornelis E.C.A. Hop and Harvey WongDrug Metabolism and Disposition September 2022, 50 (9) 1170-1181; DOI: https://doi.org/10.1124/dmd.122.000885
Huang, Shiew-Mei
- You have accessTransporters in Regulatory Science: Notable Contributions from Dr. Giacomini in the Past Two DecadesLei Zhang, Qi Liu, Shiew-Mei Huang and Robert LionbergerDrug Metabolism and Disposition September 2022, 50 (9) 1211-1217; DOI: https://doi.org/10.1124/dmd.121.000706
Hurtarte, Milena
- You have accessImpact of Inflammation and Infection on the Expression of Amino Acid Transporters in the Placenta: A MinireviewEliza R. McColl, Milena Hurtarte and Micheline Piquette-MillerDrug Metabolism and Disposition September 2022, 50 (9) 1251-1258; DOI: https://doi.org/10.1124/dmd.121.000703
J
Jones, Dean P.
- You have accessHigh-Throughput Production of Diverse Xenobiotic Metabolites with Cytochrome P450–Transduced Huh7 Hepatoma Cell LinesChoon-myung Lee, Ken H. Liu, Grant Singer, Gary W. Miller, Shuzhao Li, Dean P. Jones and Edward T. MorganDrug Metabolism and Disposition September 2022, 50 (9) 1182-1189; DOI: https://doi.org/10.1124/dmd.122.000900
Joy, Melanie S.
- You have accessPhysiologically Based Pharmacokinetic Modeling of Vitamin D3 and Metabolites in Vitamin D–Insufficient PatientsColton W. Sawyer, Stacey M. Tuey, Raymond E. West, Thomas D. Nolin and Melanie S. JoyDrug Metabolism and Disposition September 2022, 50 (9) 1161-1169; DOI: https://doi.org/10.1124/dmd.121.000609
K
Kalgutkar, Amit S.
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
Kobayashi, Masaki
- You have accessThe rs35217482 (T755I) Single-Nucleotide Polymorphism in Aldehyde Oxidase-1 Attenuates Protein Dimer Formation and Reduces the Rates of Phthalazine MetabolismHinata Ueda, Katsuya Narumi, Ayako Furugen, Yoshitaka Saito and Masaki KobayashiDrug Metabolism and Disposition September 2022, 50 (9) 1126-1131; DOI: https://doi.org/10.1124/dmd.122.000902
L
Lai, Yurong
- You have accessSpecial Section on New Era of Transporter Science: Unraveling the Functional Role of Orphan Transporters–EditorialYurong Lai and Xiao-bo ZhongDrug Metabolism and Disposition September 2022, 50 (9) 1190-1192; DOI: https://doi.org/10.1124/dmd.122.001014
Landers, Connor
- You have accessDefining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting ApproachAngela C. Doran, Woodrow Burchett, Connor Landers, Gabrielle M. Gualtieri, Amanda Balesano, Heather Eng, Alyssa L Dantonio, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1259-1271; DOI: https://doi.org/10.1124/dmd.122.000884
- You have accessAn Improved Method for Cytochrome P450 Reaction Phenotyping Using a Sequential Qualitative-Then-Quantitative ApproachAngela C. Doran, Alyssa L. Dantonio, Gabrielle M. Gualtieri, Amanda Balesano, Connor Landers, Woodrow Burchett, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1272-1286; DOI: https://doi.org/10.1124/dmd.122.000883
Lee, Choon-myung
- You have accessHigh-Throughput Production of Diverse Xenobiotic Metabolites with Cytochrome P450–Transduced Huh7 Hepatoma Cell LinesChoon-myung Lee, Ken H. Liu, Grant Singer, Gary W. Miller, Shuzhao Li, Dean P. Jones and Edward T. MorganDrug Metabolism and Disposition September 2022, 50 (9) 1182-1189; DOI: https://doi.org/10.1124/dmd.122.000900
Li, Shuzhao
- You have accessHigh-Throughput Production of Diverse Xenobiotic Metabolites with Cytochrome P450–Transduced Huh7 Hepatoma Cell LinesChoon-myung Lee, Ken H. Liu, Grant Singer, Gary W. Miller, Shuzhao Li, Dean P. Jones and Edward T. MorganDrug Metabolism and Disposition September 2022, 50 (9) 1182-1189; DOI: https://doi.org/10.1124/dmd.122.000900
Lin, Louis
- You have accessPhysiologically Based Pharmacokinetic Models Can Be Used to Predict the Unique Nonlinear Absorption Profiles of VismodegibLouis Lin, Matthew R. Wright, Cornelis E.C.A. Hop and Harvey WongDrug Metabolism and Disposition September 2022, 50 (9) 1170-1181; DOI: https://doi.org/10.1124/dmd.122.000885
Lionberger, Robert
- You have accessTransporters in Regulatory Science: Notable Contributions from Dr. Giacomini in the Past Two DecadesLei Zhang, Qi Liu, Shiew-Mei Huang and Robert LionbergerDrug Metabolism and Disposition September 2022, 50 (9) 1211-1217; DOI: https://doi.org/10.1124/dmd.121.000706
Litchfield, John
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
Liu, Ken H.
- You have accessHigh-Throughput Production of Diverse Xenobiotic Metabolites with Cytochrome P450–Transduced Huh7 Hepatoma Cell LinesChoon-myung Lee, Ken H. Liu, Grant Singer, Gary W. Miller, Shuzhao Li, Dean P. Jones and Edward T. MorganDrug Metabolism and Disposition September 2022, 50 (9) 1182-1189; DOI: https://doi.org/10.1124/dmd.122.000900
Liu, Qi
- You have accessTransporters in Regulatory Science: Notable Contributions from Dr. Giacomini in the Past Two DecadesLei Zhang, Qi Liu, Shiew-Mei Huang and Robert LionbergerDrug Metabolism and Disposition September 2022, 50 (9) 1211-1217; DOI: https://doi.org/10.1124/dmd.121.000706
Liu, William
- You have accessThe COVID-19 Oral Drug Molnupiravir Is a CES2 Substrate: Potential Drug-Drug Interactions and Impact of CES2 Genetic Polymorphism In VitroYue Shen, William Eades, William Liu and Bingfang YanDrug Metabolism and Disposition September 2022, 50 (9) 1151-1160; DOI: https://doi.org/10.1124/dmd.122.000918
Liu, Yingrui
- You have accessAntibiotics-Induced Disruption of Gut Microbiota Increases Systemic Exposure of Clopidogrel Active Metabolite in Type 2 Diabetic RatsXue Chen, Yingrui Liu, Hongwei Yao, Wenfang Song, Yu Song, Jingkai Gu and Yingjie GuoDrug Metabolism and Disposition September 2022, 50 (9) 1142-1150; DOI: https://doi.org/10.1124/dmd.122.000906
López Quiñones, Antonio J.
- You have accessClinical Applications and the Roles of Transporters in Disposition, Tumor Targeting, and Tissue Toxicity of meta-IodobenzylguanidineAntonio J. López Quiñones, Letícia Salvador Vieira and Joanne WangDrug Metabolism and Disposition September 2022, 50 (9) 1218-1227; DOI: https://doi.org/10.1124/dmd.121.000707
Luo, Qi
- Open AccessAmino Acid Solute Carrier Transporters in Inflammation and AutoimmunityLinlin Sheng, Qi Luo and Ligong ChenDrug Metabolism and Disposition September 2022, 50 (9) 1228-1237; DOI: https://doi.org/10.1124/dmd.121.000705
M
Mathialagan, Sumathy
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
McColl, Eliza R.
- You have accessImpact of Inflammation and Infection on the Expression of Amino Acid Transporters in the Placenta: A MinireviewEliza R. McColl, Milena Hurtarte and Micheline Piquette-MillerDrug Metabolism and Disposition September 2022, 50 (9) 1251-1258; DOI: https://doi.org/10.1124/dmd.121.000703
Miller, Gary W.
- You have accessHigh-Throughput Production of Diverse Xenobiotic Metabolites with Cytochrome P450–Transduced Huh7 Hepatoma Cell LinesChoon-myung Lee, Ken H. Liu, Grant Singer, Gary W. Miller, Shuzhao Li, Dean P. Jones and Edward T. MorganDrug Metabolism and Disposition September 2022, 50 (9) 1182-1189; DOI: https://doi.org/10.1124/dmd.122.000900
Morgan, Edward T.
- You have accessHigh-Throughput Production of Diverse Xenobiotic Metabolites with Cytochrome P450–Transduced Huh7 Hepatoma Cell LinesChoon-myung Lee, Ken H. Liu, Grant Singer, Gary W. Miller, Shuzhao Li, Dean P. Jones and Edward T. MorganDrug Metabolism and Disposition September 2022, 50 (9) 1182-1189; DOI: https://doi.org/10.1124/dmd.122.000900
N
Narumi, Katsuya
- You have accessThe rs35217482 (T755I) Single-Nucleotide Polymorphism in Aldehyde Oxidase-1 Attenuates Protein Dimer Formation and Reduces the Rates of Phthalazine MetabolismHinata Ueda, Katsuya Narumi, Ayako Furugen, Yoshitaka Saito and Masaki KobayashiDrug Metabolism and Disposition September 2022, 50 (9) 1126-1131; DOI: https://doi.org/10.1124/dmd.122.000902
Nolin, Thomas D.
- You have accessPhysiologically Based Pharmacokinetic Modeling of Vitamin D3 and Metabolites in Vitamin D–Insufficient PatientsColton W. Sawyer, Stacey M. Tuey, Raymond E. West, Thomas D. Nolin and Melanie S. JoyDrug Metabolism and Disposition September 2022, 50 (9) 1161-1169; DOI: https://doi.org/10.1124/dmd.121.000609
O
Obach, R. Scott
- You have accessDefining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting ApproachAngela C. Doran, Woodrow Burchett, Connor Landers, Gabrielle M. Gualtieri, Amanda Balesano, Heather Eng, Alyssa L Dantonio, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1259-1271; DOI: https://doi.org/10.1124/dmd.122.000884
- You have accessAn Improved Method for Cytochrome P450 Reaction Phenotyping Using a Sequential Qualitative-Then-Quantitative ApproachAngela C. Doran, Alyssa L. Dantonio, Gabrielle M. Gualtieri, Amanda Balesano, Connor Landers, Woodrow Burchett, Theunis C. Goosen and R. Scott ObachDrug Metabolism and Disposition September 2022, 50 (9) 1272-1286; DOI: https://doi.org/10.1124/dmd.122.000883
P
Piquette-Miller, Micheline
- You have accessImpact of Inflammation and Infection on the Expression of Amino Acid Transporters in the Placenta: A MinireviewEliza R. McColl, Milena Hurtarte and Micheline Piquette-MillerDrug Metabolism and Disposition September 2022, 50 (9) 1251-1258; DOI: https://doi.org/10.1124/dmd.121.000703
R
Rettie, Allan E.
- You have accessPharmacokinetic Modeling of Warfarin ІI – Model-Based Analysis of Warfarin Metabolites after Warfarin Administered Either Alone or Together with Fluconazole or RifampinShen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. TracyDrug Metabolism and Disposition September 2022, 50 (9) 1302-1311; DOI: https://doi.org/10.1124/dmd.122.000877
- You have accessPharmacokinetic Modeling of Warfarin І – Model-Based Analysis of Warfarin Enantiomers with a Target Mediated Drug Disposition Model Reveals CYP2C9 Genotype-Dependent Drug-Drug Interactions of S-WarfarinShen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. TracyDrug Metabolism and Disposition September 2022, 50 (9) 1287-1301; DOI: https://doi.org/10.1124/dmd.122.000876
Riccardi, Keith
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
Rodrigues, A. David
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
S
Saito, Yoshitaka
- You have accessThe rs35217482 (T755I) Single-Nucleotide Polymorphism in Aldehyde Oxidase-1 Attenuates Protein Dimer Formation and Reduces the Rates of Phthalazine MetabolismHinata Ueda, Katsuya Narumi, Ayako Furugen, Yoshitaka Saito and Masaki KobayashiDrug Metabolism and Disposition September 2022, 50 (9) 1126-1131; DOI: https://doi.org/10.1124/dmd.122.000902
Sawyer, Colton W.
- You have accessPhysiologically Based Pharmacokinetic Modeling of Vitamin D3 and Metabolites in Vitamin D–Insufficient PatientsColton W. Sawyer, Stacey M. Tuey, Raymond E. West, Thomas D. Nolin and Melanie S. JoyDrug Metabolism and Disposition September 2022, 50 (9) 1161-1169; DOI: https://doi.org/10.1124/dmd.121.000609
Shen, Yue
- You have accessThe COVID-19 Oral Drug Molnupiravir Is a CES2 Substrate: Potential Drug-Drug Interactions and Impact of CES2 Genetic Polymorphism In VitroYue Shen, William Eades, William Liu and Bingfang YanDrug Metabolism and Disposition September 2022, 50 (9) 1151-1160; DOI: https://doi.org/10.1124/dmd.122.000918
Sheng, Linlin
- Open AccessAmino Acid Solute Carrier Transporters in Inflammation and AutoimmunityLinlin Sheng, Qi Luo and Ligong ChenDrug Metabolism and Disposition September 2022, 50 (9) 1228-1237; DOI: https://doi.org/10.1124/dmd.121.000705
Shu, Yan
- You have accessTranscriptional Regulation of Solute Carrier Drug TransportersShiwei Zhou and Yan ShuDrug Metabolism and Disposition September 2022, 50 (9) 1238-1250; DOI: https://doi.org/10.1124/dmd.121.000704
Singer, Grant
- You have accessHigh-Throughput Production of Diverse Xenobiotic Metabolites with Cytochrome P450–Transduced Huh7 Hepatoma Cell LinesChoon-myung Lee, Ken H. Liu, Grant Singer, Gary W. Miller, Shuzhao Li, Dean P. Jones and Edward T. MorganDrug Metabolism and Disposition September 2022, 50 (9) 1182-1189; DOI: https://doi.org/10.1124/dmd.122.000900
Song, Wenfang
- You have accessAntibiotics-Induced Disruption of Gut Microbiota Increases Systemic Exposure of Clopidogrel Active Metabolite in Type 2 Diabetic RatsXue Chen, Yingrui Liu, Hongwei Yao, Wenfang Song, Yu Song, Jingkai Gu and Yingjie GuoDrug Metabolism and Disposition September 2022, 50 (9) 1142-1150; DOI: https://doi.org/10.1124/dmd.122.000906
Song, Yu
- You have accessAntibiotics-Induced Disruption of Gut Microbiota Increases Systemic Exposure of Clopidogrel Active Metabolite in Type 2 Diabetic RatsXue Chen, Yingrui Liu, Hongwei Yao, Wenfang Song, Yu Song, Jingkai Gu and Yingjie GuoDrug Metabolism and Disposition September 2022, 50 (9) 1142-1150; DOI: https://doi.org/10.1124/dmd.122.000906
Storelli, Flavia
- You have accessIs the Protein-Mediated Uptake of Drugs by Organic Anion Transporting Polypeptides a Real Phenomenon or an Artifact?Mengyue Yin, Flavia Storelli and Jashvant D. UnadkatDrug Metabolism and Disposition September 2022, 50 (9) 1132-1141; DOI: https://doi.org/10.1124/dmd.122.000849
T
Tess, David A.
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
Tracy, Timothy S.
- You have accessPharmacokinetic Modeling of Warfarin ІI – Model-Based Analysis of Warfarin Metabolites after Warfarin Administered Either Alone or Together with Fluconazole or RifampinShen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. TracyDrug Metabolism and Disposition September 2022, 50 (9) 1302-1311; DOI: https://doi.org/10.1124/dmd.122.000877
- You have accessPharmacokinetic Modeling of Warfarin І – Model-Based Analysis of Warfarin Enantiomers with a Target Mediated Drug Disposition Model Reveals CYP2C9 Genotype-Dependent Drug-Drug Interactions of S-WarfarinShen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. TracyDrug Metabolism and Disposition September 2022, 50 (9) 1287-1301; DOI: https://doi.org/10.1124/dmd.122.000876
Tseng, Elaine
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
Tuey, Stacey M.
- You have accessPhysiologically Based Pharmacokinetic Modeling of Vitamin D3 and Metabolites in Vitamin D–Insufficient PatientsColton W. Sawyer, Stacey M. Tuey, Raymond E. West, Thomas D. Nolin and Melanie S. JoyDrug Metabolism and Disposition September 2022, 50 (9) 1161-1169; DOI: https://doi.org/10.1124/dmd.121.000609
U
Ueda, Hinata
- You have accessThe rs35217482 (T755I) Single-Nucleotide Polymorphism in Aldehyde Oxidase-1 Attenuates Protein Dimer Formation and Reduces the Rates of Phthalazine MetabolismHinata Ueda, Katsuya Narumi, Ayako Furugen, Yoshitaka Saito and Masaki KobayashiDrug Metabolism and Disposition September 2022, 50 (9) 1126-1131; DOI: https://doi.org/10.1124/dmd.122.000902
Unadkat, Jashvant D.
- You have accessIs the Protein-Mediated Uptake of Drugs by Organic Anion Transporting Polypeptides a Real Phenomenon or an Artifact?Mengyue Yin, Flavia Storelli and Jashvant D. UnadkatDrug Metabolism and Disposition September 2022, 50 (9) 1132-1141; DOI: https://doi.org/10.1124/dmd.122.000849
V
Varma, Manthena V. S.
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
Vieira, Letícia Salvador
- You have accessClinical Applications and the Roles of Transporters in Disposition, Tumor Targeting, and Tissue Toxicity of meta-IodobenzylguanidineAntonio J. López Quiñones, Letícia Salvador Vieira and Joanne WangDrug Metabolism and Disposition September 2022, 50 (9) 1218-1227; DOI: https://doi.org/10.1124/dmd.121.000707
W
Wang, Joanne
- You have accessClinical Applications and the Roles of Transporters in Disposition, Tumor Targeting, and Tissue Toxicity of meta-IodobenzylguanidineAntonio J. López Quiñones, Letícia Salvador Vieira and Joanne WangDrug Metabolism and Disposition September 2022, 50 (9) 1218-1227; DOI: https://doi.org/10.1124/dmd.121.000707
Weng, Yan
- You have accessTransporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver DiseaseYan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. VarmaDrug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
West, Raymond E.
- You have accessPhysiologically Based Pharmacokinetic Modeling of Vitamin D3 and Metabolites in Vitamin D–Insufficient PatientsColton W. Sawyer, Stacey M. Tuey, Raymond E. West, Thomas D. Nolin and Melanie S. JoyDrug Metabolism and Disposition September 2022, 50 (9) 1161-1169; DOI: https://doi.org/10.1124/dmd.121.000609
Wong, Harvey
- You have accessPhysiologically Based Pharmacokinetic Models Can Be Used to Predict the Unique Nonlinear Absorption Profiles of VismodegibLouis Lin, Matthew R. Wright, Cornelis E.C.A. Hop and Harvey WongDrug Metabolism and Disposition September 2022, 50 (9) 1170-1181; DOI: https://doi.org/10.1124/dmd.122.000885
Wright, Matthew R.
- You have accessPhysiologically Based Pharmacokinetic Models Can Be Used to Predict the Unique Nonlinear Absorption Profiles of VismodegibLouis Lin, Matthew R. Wright, Cornelis E.C.A. Hop and Harvey WongDrug Metabolism and Disposition September 2022, 50 (9) 1170-1181; DOI: https://doi.org/10.1124/dmd.122.000885
Y
Yan, Bingfang
- You have accessThe COVID-19 Oral Drug Molnupiravir Is a CES2 Substrate: Potential Drug-Drug Interactions and Impact of CES2 Genetic Polymorphism In VitroYue Shen, William Eades, William Liu and Bingfang YanDrug Metabolism and Disposition September 2022, 50 (9) 1151-1160; DOI: https://doi.org/10.1124/dmd.122.000918
Yao, Hongwei
- You have accessAntibiotics-Induced Disruption of Gut Microbiota Increases Systemic Exposure of Clopidogrel Active Metabolite in Type 2 Diabetic RatsXue Chen, Yingrui Liu, Hongwei Yao, Wenfang Song, Yu Song, Jingkai Gu and Yingjie GuoDrug Metabolism and Disposition September 2022, 50 (9) 1142-1150; DOI: https://doi.org/10.1124/dmd.122.000906
Yee, Sook Wah
- You have accessEmerging Roles of the Human Solute Carrier 22 FamilySook Wah Yee and Kathleen M. GiacominiDrug Metabolism and Disposition September 2022, 50 (9) 1193-1210; DOI: https://doi.org/10.1124/dmd.121.000702
Yin, Mengyue
- You have accessIs the Protein-Mediated Uptake of Drugs by Organic Anion Transporting Polypeptides a Real Phenomenon or an Artifact?Mengyue Yin, Flavia Storelli and Jashvant D. UnadkatDrug Metabolism and Disposition September 2022, 50 (9) 1132-1141; DOI: https://doi.org/10.1124/dmd.122.000849
Z
Zhang, Lei
- You have accessTransporters in Regulatory Science: Notable Contributions from Dr. Giacomini in the Past Two DecadesLei Zhang, Qi Liu, Shiew-Mei Huang and Robert LionbergerDrug Metabolism and Disposition September 2022, 50 (9) 1211-1217; DOI: https://doi.org/10.1124/dmd.121.000706
Zhong, Xiao-bo
- You have accessSpecial Section on New Era of Transporter Science: Unraveling the Functional Role of Orphan Transporters–EditorialYurong Lai and Xiao-bo ZhongDrug Metabolism and Disposition September 2022, 50 (9) 1190-1192; DOI: https://doi.org/10.1124/dmd.122.001014
Zhou, Shiwei
- You have accessTranscriptional Regulation of Solute Carrier Drug TransportersShiwei Zhou and Yan ShuDrug Metabolism and Disposition September 2022, 50 (9) 1238-1250; DOI: https://doi.org/10.1124/dmd.121.000704
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