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Index by author

January 01, 2023; Volume 51,Issue 1

A

  1. Abeysinghe, Stephenie

    1. Gut Microbiome–Wide Search for Bacterial Azoreductases Reveals Potentially Uncharacterized Azoreductases Encoded in the Human Gut Microbiome
      Domenick J. Braccia, Glory Minabou Ndjite, Ashley Weiss, Sophia Levy, Stephenie Abeysinghe, Xiaofang Jiang, Mihai Pop and Brantley Hall
      Drug Metabolism and Disposition January 2023, 51 (1) 142-153; DOI: https://doi.org/10.1124/dmd.122.000898

  2. Amai, Keito

    1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver
      Hiroyuki Ichida, Tatsuki Fukami, Keito Amai, Kohei Suzuki, Kenji Mishiro, Shiori Takano, Wataru Obuchi, Zhengyu Zhang, Akiko Watanabe, Masataka Nakano, Kengo Watanabe and Miki Nakajima
      Drug Metabolism and Disposition January 2023, 51 (1) 17-28; DOI: https://doi.org/10.1124/dmd.122.001037

  3. Asano, Daigo

    1. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver
      Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe and Kouichi Yoshinari
      Drug Metabolism and Disposition January 2023, 51 (1) 67-80; DOI: https://doi.org/10.1124/dmd.122.001000

B

  1. Bamfo, Nadia O

    1. Stereoselective Metabolism of Bupropion to Active Metabolites in Cellular Fractions of Human Liver and Intestine
      Nadia O Bamfo, Jessica BL Lu and Zeruesenay Desta
      Drug Metabolism and Disposition January 2023, 51 (1) 54-66; DOI: https://doi.org/10.1124/dmd.122.000867

  2. Braccia, Domenick J.

    1. Gut Microbiome–Wide Search for Bacterial Azoreductases Reveals Potentially Uncharacterized Azoreductases Encoded in the Human Gut Microbiome
      Domenick J. Braccia, Glory Minabou Ndjite, Ashley Weiss, Sophia Levy, Stephenie Abeysinghe, Xiaofang Jiang, Mihai Pop and Brantley Hall
      Drug Metabolism and Disposition January 2023, 51 (1) 142-153; DOI: https://doi.org/10.1124/dmd.122.000898

C

  1. Chen, Gang

    1. Open Access
      CYP2C19 Plays a Major Role in the Hepatic N-Oxidation of Cotinine
      Yadira X. Perez-Paramo, Christy J.W. Watson, Gang Chen and Philip Lazarus
      Drug Metabolism and Disposition January 2023, 51 (1) 29-37; DOI: https://doi.org/10.1124/dmd.121.000624

  2. Chen, Jian

    1. Covalent Binding Mechanism of Furmonertinib and Osimertinib With Human Serum Albumin
      Yali Wu, Lili Chen, Jian Chen, Hao Xue, Qingfeng He, Dafang Zhong and Xingxing Diao
      Drug Metabolism and Disposition January 2023, 51 (1) 8-16; DOI: https://doi.org/10.1124/dmd.122.001019

  3. Chen, Lili

    1. Covalent Binding Mechanism of Furmonertinib and Osimertinib With Human Serum Albumin
      Yali Wu, Lili Chen, Jian Chen, Hao Xue, Qingfeng He, Dafang Zhong and Xingxing Diao
      Drug Metabolism and Disposition January 2023, 51 (1) 8-16; DOI: https://doi.org/10.1124/dmd.122.001019

  4. Croyle, Maria A.

    1. COVID-19 Vaccines and the Virus: Impact on Drug Metabolism and Pharmacokinetics
      Eliza R. McColl, Maria A. Croyle, William C. Zamboni, William G. Honer, Mark Heise, Micheline Piquette-Miller and Kerry B. Goralski
      Drug Metabolism and Disposition January 2023, 51 (1) 130-141; DOI: https://doi.org/10.1124/dmd.122.000934

D

  1. Desta, Zeruesenay

    1. Stereoselective Metabolism of Bupropion to Active Metabolites in Cellular Fractions of Human Liver and Intestine
      Nadia O Bamfo, Jessica BL Lu and Zeruesenay Desta
      Drug Metabolism and Disposition January 2023, 51 (1) 54-66; DOI: https://doi.org/10.1124/dmd.122.000867

  2. Diao, Xingxing

    1. Covalent Binding Mechanism of Furmonertinib and Osimertinib With Human Serum Albumin
      Yali Wu, Lili Chen, Jian Chen, Hao Xue, Qingfeng He, Dafang Zhong and Xingxing Diao
      Drug Metabolism and Disposition January 2023, 51 (1) 8-16; DOI: https://doi.org/10.1124/dmd.122.001019

  3. Ding, Xinxin

    1. Detection of Transgene Location in the CYP2A13/2B6/2F1-transgenic Mouse Model using Optical Genome Mapping Technology
      Xinxin Ding, John Han, Laura S. Van Winkle and Qing-Yu Zhang
      Drug Metabolism and Disposition January 2023, 51 (1) 46-53; DOI: https://doi.org/10.1124/dmd.122.001090
    2. Celebrating 50 Years of Excellence in DMD Science
      Xinxin Ding
      Drug Metabolism and Disposition January 2023, 51 (1) 96-98; DOI: https://doi.org/10.1124/dmd.122.001179

E

  1. El-Kadi, Ayman O.S.

    1. Sexual Dimorphism in the Expression of Cytochrome P450 Enzymes in Rat Heart, Liver, Kidney, Lung, Brain, and Small Intestine
      Sexual Dimorphism in the Expression of Cytochrome P450 Enzymes in Rat Heart, Liver, Kidney, Lung, Brain, and Small Intestine
      Samar H. Gerges and Ayman O.S. El-Kadi
      Drug Metabolism and Disposition January 2023, 51 (1) 81-94; DOI: https://doi.org/10.1124/dmd.122.000915

F

  1. Fukami, Tatsuki

    1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver
      Hiroyuki Ichida, Tatsuki Fukami, Keito Amai, Kohei Suzuki, Kenji Mishiro, Shiori Takano, Wataru Obuchi, Zhengyu Zhang, Akiko Watanabe, Masataka Nakano, Kengo Watanabe and Miki Nakajima
      Drug Metabolism and Disposition January 2023, 51 (1) 17-28; DOI: https://doi.org/10.1124/dmd.122.001037

G

  1. Gao, Huanyao

    1. Open Access
      Cytochrome P450 Transcriptional Regulation by Testis‐Specific Y‐Encoded‐Like Protein: Identification of Novel Upstream Transcription Factors
      Suganti Shivaram, Huanyao Gao, Sisi Qin, Duan Liu, Richard M. Weinshilboum and Liewei Wang
      Drug Metabolism and Disposition January 2023, 51 (1) 1-7; DOI: https://doi.org/10.1124/dmd.122.000945

  2. Gerges, Samar H.

    1. Sexual Dimorphism in the Expression of Cytochrome P450 Enzymes in Rat Heart, Liver, Kidney, Lung, Brain, and Small Intestine
      Sexual Dimorphism in the Expression of Cytochrome P450 Enzymes in Rat Heart, Liver, Kidney, Lung, Brain, and Small Intestine
      Samar H. Gerges and Ayman O.S. El-Kadi
      Drug Metabolism and Disposition January 2023, 51 (1) 81-94; DOI: https://doi.org/10.1124/dmd.122.000915

  3. Goralski, Kerry B.

    1. COVID-19 Vaccines and the Virus: Impact on Drug Metabolism and Pharmacokinetics
      Eliza R. McColl, Maria A. Croyle, William C. Zamboni, William G. Honer, Mark Heise, Micheline Piquette-Miller and Kerry B. Goralski
      Drug Metabolism and Disposition January 2023, 51 (1) 130-141; DOI: https://doi.org/10.1124/dmd.122.000934

  4. Guengerich, F. Peter

    1. Drug Metabolism: A Half-Century Plus of Progress, Continued Needs, and New Opportunities
      F. Peter Guengerich
      Drug Metabolism and Disposition January 2023, 51 (1) 99-104; DOI: https://doi.org/10.1124/dmd.121.000739

H

  1. Hall, Brantley

    1. Gut Microbiome–Wide Search for Bacterial Azoreductases Reveals Potentially Uncharacterized Azoreductases Encoded in the Human Gut Microbiome
      Domenick J. Braccia, Glory Minabou Ndjite, Ashley Weiss, Sophia Levy, Stephenie Abeysinghe, Xiaofang Jiang, Mihai Pop and Brantley Hall
      Drug Metabolism and Disposition January 2023, 51 (1) 142-153; DOI: https://doi.org/10.1124/dmd.122.000898

  2. Halpert, James R.

    1. Four Decades of Cytochrome P450 2B Research: From Protein Adducts to Protein Structures and Beyond
      Arthur G. Roberts, Jeffrey C. Stevens, Grazyna D. Szklarz, Emily E. Scott, Santosh Kumar, Manish B. Shah and James R. Halpert
      Drug Metabolism and Disposition January 2023, 51 (1) 111-122; DOI: https://doi.org/10.1124/dmd.122.001109
    2. The Evolution of Drug Metabolism and Disposition: A Perspective From the Editors
      Edward T. Morgan, Raymond F. Novak, James R. Halpert, Eric F. Johnson and Jeffrey C. Stevens
      Drug Metabolism and Disposition January 2023, 51 (1) 105-110; DOI: https://doi.org/10.1124/dmd.122.000986

  3. Hamada, Takakazu

    1. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver
      Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe and Kouichi Yoshinari
      Drug Metabolism and Disposition January 2023, 51 (1) 67-80; DOI: https://doi.org/10.1124/dmd.122.001000

  4. Han, John

    1. Detection of Transgene Location in the CYP2A13/2B6/2F1-transgenic Mouse Model using Optical Genome Mapping Technology
      Xinxin Ding, John Han, Laura S. Van Winkle and Qing-Yu Zhang
      Drug Metabolism and Disposition January 2023, 51 (1) 46-53; DOI: https://doi.org/10.1124/dmd.122.001090

  5. He, Qingfeng

    1. Covalent Binding Mechanism of Furmonertinib and Osimertinib With Human Serum Albumin
      Yali Wu, Lili Chen, Jian Chen, Hao Xue, Qingfeng He, Dafang Zhong and Xingxing Diao
      Drug Metabolism and Disposition January 2023, 51 (1) 8-16; DOI: https://doi.org/10.1124/dmd.122.001019

  6. Heise, Mark

    1. COVID-19 Vaccines and the Virus: Impact on Drug Metabolism and Pharmacokinetics
      Eliza R. McColl, Maria A. Croyle, William C. Zamboni, William G. Honer, Mark Heise, Micheline Piquette-Miller and Kerry B. Goralski
      Drug Metabolism and Disposition January 2023, 51 (1) 130-141; DOI: https://doi.org/10.1124/dmd.122.000934

  7. Honer, William G.

    1. COVID-19 Vaccines and the Virus: Impact on Drug Metabolism and Pharmacokinetics
      Eliza R. McColl, Maria A. Croyle, William C. Zamboni, William G. Honer, Mark Heise, Micheline Piquette-Miller and Kerry B. Goralski
      Drug Metabolism and Disposition January 2023, 51 (1) 130-141; DOI: https://doi.org/10.1124/dmd.122.000934

I

  1. Ichida, Hiroyuki

    1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver
      Hiroyuki Ichida, Tatsuki Fukami, Keito Amai, Kohei Suzuki, Kenji Mishiro, Shiori Takano, Wataru Obuchi, Zhengyu Zhang, Akiko Watanabe, Masataka Nakano, Kengo Watanabe and Miki Nakajima
      Drug Metabolism and Disposition January 2023, 51 (1) 17-28; DOI: https://doi.org/10.1124/dmd.122.001037

  2. Inoue, Shin-ichi

    1. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver
      Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe and Kouichi Yoshinari
      Drug Metabolism and Disposition January 2023, 51 (1) 67-80; DOI: https://doi.org/10.1124/dmd.122.001000

J

  1. Jiang, Xiaofang

    1. Gut Microbiome–Wide Search for Bacterial Azoreductases Reveals Potentially Uncharacterized Azoreductases Encoded in the Human Gut Microbiome
      Domenick J. Braccia, Glory Minabou Ndjite, Ashley Weiss, Sophia Levy, Stephenie Abeysinghe, Xiaofang Jiang, Mihai Pop and Brantley Hall
      Drug Metabolism and Disposition January 2023, 51 (1) 142-153; DOI: https://doi.org/10.1124/dmd.122.000898

  2. Jikuya, Shiori

    1. A Comprehensive Investigation of Dog Cytochrome P450 3A (CYP3A) Reveals a Functional Role of Newly Identified CYP3A98 in Small Intestine
      A Comprehensive Investigation of Dog Cytochrome P450 3A (CYP3A) Reveals a Functional Role of Newly Identified CYP3A98 in Small Intestine
      Yasuhiro Uno, Shiori Jikuya, Yutaro Noda, Norie Murayama and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2023, 51 (1) 38-45; DOI: https://doi.org/10.1124/dmd.121.000749

  3. Johnson, Eric F.

    1. The Evolution of Drug Metabolism and Disposition: A Perspective From the Editors
      Edward T. Morgan, Raymond F. Novak, James R. Halpert, Eric F. Johnson and Jeffrey C. Stevens
      Drug Metabolism and Disposition January 2023, 51 (1) 105-110; DOI: https://doi.org/10.1124/dmd.122.000986

K

  1. Kumar, Santosh

    1. Four Decades of Cytochrome P450 2B Research: From Protein Adducts to Protein Structures and Beyond
      Arthur G. Roberts, Jeffrey C. Stevens, Grazyna D. Szklarz, Emily E. Scott, Santosh Kumar, Manish B. Shah and James R. Halpert
      Drug Metabolism and Disposition January 2023, 51 (1) 111-122; DOI: https://doi.org/10.1124/dmd.122.001109

L

  1. Lazarus, Philip

    1. Open Access
      CYP2C19 Plays a Major Role in the Hepatic N-Oxidation of Cotinine
      Yadira X. Perez-Paramo, Christy J.W. Watson, Gang Chen and Philip Lazarus
      Drug Metabolism and Disposition January 2023, 51 (1) 29-37; DOI: https://doi.org/10.1124/dmd.121.000624

  2. Levy, Sophia

    1. Gut Microbiome–Wide Search for Bacterial Azoreductases Reveals Potentially Uncharacterized Azoreductases Encoded in the Human Gut Microbiome
      Domenick J. Braccia, Glory Minabou Ndjite, Ashley Weiss, Sophia Levy, Stephenie Abeysinghe, Xiaofang Jiang, Mihai Pop and Brantley Hall
      Drug Metabolism and Disposition January 2023, 51 (1) 142-153; DOI: https://doi.org/10.1124/dmd.122.000898

  3. Liu, Duan

    1. Open Access
      Cytochrome P450 Transcriptional Regulation by Testis‐Specific Y‐Encoded‐Like Protein: Identification of Novel Upstream Transcription Factors
      Suganti Shivaram, Huanyao Gao, Sisi Qin, Duan Liu, Richard M. Weinshilboum and Liewei Wang
      Drug Metabolism and Disposition January 2023, 51 (1) 1-7; DOI: https://doi.org/10.1124/dmd.122.000945

  4. Lu, Jessica BL

    1. Stereoselective Metabolism of Bupropion to Active Metabolites in Cellular Fractions of Human Liver and Intestine
      Nadia O Bamfo, Jessica BL Lu and Zeruesenay Desta
      Drug Metabolism and Disposition January 2023, 51 (1) 54-66; DOI: https://doi.org/10.1124/dmd.122.000867

M

  1. McColl, Eliza R.

    1. COVID-19 Vaccines and the Virus: Impact on Drug Metabolism and Pharmacokinetics
      Eliza R. McColl, Maria A. Croyle, William C. Zamboni, William G. Honer, Mark Heise, Micheline Piquette-Miller and Kerry B. Goralski
      Drug Metabolism and Disposition January 2023, 51 (1) 130-141; DOI: https://doi.org/10.1124/dmd.122.000934

  2. Minabou Ndjite, Glory

    1. Gut Microbiome–Wide Search for Bacterial Azoreductases Reveals Potentially Uncharacterized Azoreductases Encoded in the Human Gut Microbiome
      Domenick J. Braccia, Glory Minabou Ndjite, Ashley Weiss, Sophia Levy, Stephenie Abeysinghe, Xiaofang Jiang, Mihai Pop and Brantley Hall
      Drug Metabolism and Disposition January 2023, 51 (1) 142-153; DOI: https://doi.org/10.1124/dmd.122.000898

  3. Mishiro, Kenji

    1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver
      Hiroyuki Ichida, Tatsuki Fukami, Keito Amai, Kohei Suzuki, Kenji Mishiro, Shiori Takano, Wataru Obuchi, Zhengyu Zhang, Akiko Watanabe, Masataka Nakano, Kengo Watanabe and Miki Nakajima
      Drug Metabolism and Disposition January 2023, 51 (1) 17-28; DOI: https://doi.org/10.1124/dmd.122.001037

  4. Morgan, Edward T.

    1. The Evolution of Drug Metabolism and Disposition: A Perspective From the Editors
      Edward T. Morgan, Raymond F. Novak, James R. Halpert, Eric F. Johnson and Jeffrey C. Stevens
      Drug Metabolism and Disposition January 2023, 51 (1) 105-110; DOI: https://doi.org/10.1124/dmd.122.000986

  5. Murayama, Norie

    1. A Comprehensive Investigation of Dog Cytochrome P450 3A (CYP3A) Reveals a Functional Role of Newly Identified CYP3A98 in Small Intestine
      A Comprehensive Investigation of Dog Cytochrome P450 3A (CYP3A) Reveals a Functional Role of Newly Identified CYP3A98 in Small Intestine
      Yasuhiro Uno, Shiori Jikuya, Yutaro Noda, Norie Murayama and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2023, 51 (1) 38-45; DOI: https://doi.org/10.1124/dmd.121.000749

N

  1. Nakajima, Miki

    1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver
      Hiroyuki Ichida, Tatsuki Fukami, Keito Amai, Kohei Suzuki, Kenji Mishiro, Shiori Takano, Wataru Obuchi, Zhengyu Zhang, Akiko Watanabe, Masataka Nakano, Kengo Watanabe and Miki Nakajima
      Drug Metabolism and Disposition January 2023, 51 (1) 17-28; DOI: https://doi.org/10.1124/dmd.122.001037

  2. Nakamura, Koichi

    1. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver
      Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe and Kouichi Yoshinari
      Drug Metabolism and Disposition January 2023, 51 (1) 67-80; DOI: https://doi.org/10.1124/dmd.122.001000

  3. Nakano, Masataka

    1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver
      Hiroyuki Ichida, Tatsuki Fukami, Keito Amai, Kohei Suzuki, Kenji Mishiro, Shiori Takano, Wataru Obuchi, Zhengyu Zhang, Akiko Watanabe, Masataka Nakano, Kengo Watanabe and Miki Nakajima
      Drug Metabolism and Disposition January 2023, 51 (1) 17-28; DOI: https://doi.org/10.1124/dmd.122.001037

  4. Nishiya, Yumi

    1. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver
      Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe and Kouichi Yoshinari
      Drug Metabolism and Disposition January 2023, 51 (1) 67-80; DOI: https://doi.org/10.1124/dmd.122.001000

  5. Noda, Yutaro

    1. A Comprehensive Investigation of Dog Cytochrome P450 3A (CYP3A) Reveals a Functional Role of Newly Identified CYP3A98 in Small Intestine
      A Comprehensive Investigation of Dog Cytochrome P450 3A (CYP3A) Reveals a Functional Role of Newly Identified CYP3A98 in Small Intestine
      Yasuhiro Uno, Shiori Jikuya, Yutaro Noda, Norie Murayama and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2023, 51 (1) 38-45; DOI: https://doi.org/10.1124/dmd.121.000749

  6. Novak, Raymond F.

    1. The Evolution of Drug Metabolism and Disposition: A Perspective From the Editors
      Edward T. Morgan, Raymond F. Novak, James R. Halpert, Eric F. Johnson and Jeffrey C. Stevens
      Drug Metabolism and Disposition January 2023, 51 (1) 105-110; DOI: https://doi.org/10.1124/dmd.122.000986

O

  1. Obuchi, Wataru

    1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver
      Hiroyuki Ichida, Tatsuki Fukami, Keito Amai, Kohei Suzuki, Kenji Mishiro, Shiori Takano, Wataru Obuchi, Zhengyu Zhang, Akiko Watanabe, Masataka Nakano, Kengo Watanabe and Miki Nakajima
      Drug Metabolism and Disposition January 2023, 51 (1) 17-28; DOI: https://doi.org/10.1124/dmd.122.001037

P

  1. Perez-Paramo, Yadira X.

    1. Open Access
      CYP2C19 Plays a Major Role in the Hepatic N-Oxidation of Cotinine
      Yadira X. Perez-Paramo, Christy J.W. Watson, Gang Chen and Philip Lazarus
      Drug Metabolism and Disposition January 2023, 51 (1) 29-37; DOI: https://doi.org/10.1124/dmd.121.000624

  2. Piquette-Miller, Micheline

    1. COVID-19 Vaccines and the Virus: Impact on Drug Metabolism and Pharmacokinetics
      Eliza R. McColl, Maria A. Croyle, William C. Zamboni, William G. Honer, Mark Heise, Micheline Piquette-Miller and Kerry B. Goralski
      Drug Metabolism and Disposition January 2023, 51 (1) 130-141; DOI: https://doi.org/10.1124/dmd.122.000934

  3. Pop, Mihai

    1. Gut Microbiome–Wide Search for Bacterial Azoreductases Reveals Potentially Uncharacterized Azoreductases Encoded in the Human Gut Microbiome
      Domenick J. Braccia, Glory Minabou Ndjite, Ashley Weiss, Sophia Levy, Stephenie Abeysinghe, Xiaofang Jiang, Mihai Pop and Brantley Hall
      Drug Metabolism and Disposition January 2023, 51 (1) 142-153; DOI: https://doi.org/10.1124/dmd.122.000898

Q

  1. Qin, Sisi

    1. Open Access
      Cytochrome P450 Transcriptional Regulation by Testis‐Specific Y‐Encoded‐Like Protein: Identification of Novel Upstream Transcription Factors
      Suganti Shivaram, Huanyao Gao, Sisi Qin, Duan Liu, Richard M. Weinshilboum and Liewei Wang
      Drug Metabolism and Disposition January 2023, 51 (1) 1-7; DOI: https://doi.org/10.1124/dmd.122.000945

R

  1. Roberts, Arthur G.

    1. Four Decades of Cytochrome P450 2B Research: From Protein Adducts to Protein Structures and Beyond
      Arthur G. Roberts, Jeffrey C. Stevens, Grazyna D. Szklarz, Emily E. Scott, Santosh Kumar, Manish B. Shah and James R. Halpert
      Drug Metabolism and Disposition January 2023, 51 (1) 111-122; DOI: https://doi.org/10.1124/dmd.122.001109

S

  1. Scott, Emily E.

    1. Four Decades of Cytochrome P450 2B Research: From Protein Adducts to Protein Structures and Beyond
      Arthur G. Roberts, Jeffrey C. Stevens, Grazyna D. Szklarz, Emily E. Scott, Santosh Kumar, Manish B. Shah and James R. Halpert
      Drug Metabolism and Disposition January 2023, 51 (1) 111-122; DOI: https://doi.org/10.1124/dmd.122.001109

  2. Shah, Manish B.

    1. Four Decades of Cytochrome P450 2B Research: From Protein Adducts to Protein Structures and Beyond
      Arthur G. Roberts, Jeffrey C. Stevens, Grazyna D. Szklarz, Emily E. Scott, Santosh Kumar, Manish B. Shah and James R. Halpert
      Drug Metabolism and Disposition January 2023, 51 (1) 111-122; DOI: https://doi.org/10.1124/dmd.122.001109

  3. Shibayama, Takahiro

    1. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver
      Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe and Kouichi Yoshinari
      Drug Metabolism and Disposition January 2023, 51 (1) 67-80; DOI: https://doi.org/10.1124/dmd.122.001000

  4. Shimizu, Makiko

    1. Species Specificity and Selection of Models for Drug Oxidations Mediated by Polymorphic Human Enzymes
      Species Specificity and Selection of Models for Drug Oxidations Mediated by Polymorphic Human Enzymes
      Hiroshi Yamazaki and Makiko Shimizu
      Drug Metabolism and Disposition January 2023, 51 (1) 123-129; DOI: https://doi.org/10.1124/dmd.121.000742

  5. Shinozuka, Tsuyoshi

    1. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver
      Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe and Kouichi Yoshinari
      Drug Metabolism and Disposition January 2023, 51 (1) 67-80; DOI: https://doi.org/10.1124/dmd.122.001000

  6. Shiozawa, Hideyuki

    1. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver
      Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe and Kouichi Yoshinari
      Drug Metabolism and Disposition January 2023, 51 (1) 67-80; DOI: https://doi.org/10.1124/dmd.122.001000

  7. Shivaram, Suganti

    1. Open Access
      Cytochrome P450 Transcriptional Regulation by Testis‐Specific Y‐Encoded‐Like Protein: Identification of Novel Upstream Transcription Factors
      Suganti Shivaram, Huanyao Gao, Sisi Qin, Duan Liu, Richard M. Weinshilboum and Liewei Wang
      Drug Metabolism and Disposition January 2023, 51 (1) 1-7; DOI: https://doi.org/10.1124/dmd.122.000945

  8. Stevens, Jeffrey C.

    1. Four Decades of Cytochrome P450 2B Research: From Protein Adducts to Protein Structures and Beyond
      Arthur G. Roberts, Jeffrey C. Stevens, Grazyna D. Szklarz, Emily E. Scott, Santosh Kumar, Manish B. Shah and James R. Halpert
      Drug Metabolism and Disposition January 2023, 51 (1) 111-122; DOI: https://doi.org/10.1124/dmd.122.001109
    2. The Evolution of Drug Metabolism and Disposition: A Perspective From the Editors
      Edward T. Morgan, Raymond F. Novak, James R. Halpert, Eric F. Johnson and Jeffrey C. Stevens
      Drug Metabolism and Disposition January 2023, 51 (1) 105-110; DOI: https://doi.org/10.1124/dmd.122.000986

  9. Suzuki, Kohei

    1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver
      Hiroyuki Ichida, Tatsuki Fukami, Keito Amai, Kohei Suzuki, Kenji Mishiro, Shiori Takano, Wataru Obuchi, Zhengyu Zhang, Akiko Watanabe, Masataka Nakano, Kengo Watanabe and Miki Nakajima
      Drug Metabolism and Disposition January 2023, 51 (1) 17-28; DOI: https://doi.org/10.1124/dmd.122.001037

  10. Szklarz, Grazyna D.

    1. Four Decades of Cytochrome P450 2B Research: From Protein Adducts to Protein Structures and Beyond
      Arthur G. Roberts, Jeffrey C. Stevens, Grazyna D. Szklarz, Emily E. Scott, Santosh Kumar, Manish B. Shah and James R. Halpert
      Drug Metabolism and Disposition January 2023, 51 (1) 111-122; DOI: https://doi.org/10.1124/dmd.122.001109

T

  1. Takakusa, Hideo

    1. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver
      Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe and Kouichi Yoshinari
      Drug Metabolism and Disposition January 2023, 51 (1) 67-80; DOI: https://doi.org/10.1124/dmd.122.001000

  2. Takano, Shiori

    1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver
      Hiroyuki Ichida, Tatsuki Fukami, Keito Amai, Kohei Suzuki, Kenji Mishiro, Shiori Takano, Wataru Obuchi, Zhengyu Zhang, Akiko Watanabe, Masataka Nakano, Kengo Watanabe and Miki Nakajima
      Drug Metabolism and Disposition January 2023, 51 (1) 17-28; DOI: https://doi.org/10.1124/dmd.122.001037

U

  1. Uno, Yasuhiro

    1. A Comprehensive Investigation of Dog Cytochrome P450 3A (CYP3A) Reveals a Functional Role of Newly Identified CYP3A98 in Small Intestine
      A Comprehensive Investigation of Dog Cytochrome P450 3A (CYP3A) Reveals a Functional Role of Newly Identified CYP3A98 in Small Intestine
      Yasuhiro Uno, Shiori Jikuya, Yutaro Noda, Norie Murayama and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2023, 51 (1) 38-45; DOI: https://doi.org/10.1124/dmd.121.000749

V

  1. Van Winkle, Laura S.

    1. Detection of Transgene Location in the CYP2A13/2B6/2F1-transgenic Mouse Model using Optical Genome Mapping Technology
      Xinxin Ding, John Han, Laura S. Van Winkle and Qing-Yu Zhang
      Drug Metabolism and Disposition January 2023, 51 (1) 46-53; DOI: https://doi.org/10.1124/dmd.122.001090

W

  1. Wang, Liewei

    1. Open Access
      Cytochrome P450 Transcriptional Regulation by Testis‐Specific Y‐Encoded‐Like Protein: Identification of Novel Upstream Transcription Factors
      Suganti Shivaram, Huanyao Gao, Sisi Qin, Duan Liu, Richard M. Weinshilboum and Liewei Wang
      Drug Metabolism and Disposition January 2023, 51 (1) 1-7; DOI: https://doi.org/10.1124/dmd.122.000945

  2. Watanabe, Akiko

    1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver
      Hiroyuki Ichida, Tatsuki Fukami, Keito Amai, Kohei Suzuki, Kenji Mishiro, Shiori Takano, Wataru Obuchi, Zhengyu Zhang, Akiko Watanabe, Masataka Nakano, Kengo Watanabe and Miki Nakajima
      Drug Metabolism and Disposition January 2023, 51 (1) 17-28; DOI: https://doi.org/10.1124/dmd.122.001037

  3. Watanabe, Kengo

    1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver
      Hiroyuki Ichida, Tatsuki Fukami, Keito Amai, Kohei Suzuki, Kenji Mishiro, Shiori Takano, Wataru Obuchi, Zhengyu Zhang, Akiko Watanabe, Masataka Nakano, Kengo Watanabe and Miki Nakajima
      Drug Metabolism and Disposition January 2023, 51 (1) 17-28; DOI: https://doi.org/10.1124/dmd.122.001037

  4. Watanabe, Nobuaki

    1. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver
      Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe and Kouichi Yoshinari
      Drug Metabolism and Disposition January 2023, 51 (1) 67-80; DOI: https://doi.org/10.1124/dmd.122.001000

  5. Watson, Christy J.W.

    1. Open Access
      CYP2C19 Plays a Major Role in the Hepatic N-Oxidation of Cotinine
      Yadira X. Perez-Paramo, Christy J.W. Watson, Gang Chen and Philip Lazarus
      Drug Metabolism and Disposition January 2023, 51 (1) 29-37; DOI: https://doi.org/10.1124/dmd.121.000624

  6. Weinshilboum, Richard M.

    1. Open Access
      Cytochrome P450 Transcriptional Regulation by Testis‐Specific Y‐Encoded‐Like Protein: Identification of Novel Upstream Transcription Factors
      Suganti Shivaram, Huanyao Gao, Sisi Qin, Duan Liu, Richard M. Weinshilboum and Liewei Wang
      Drug Metabolism and Disposition January 2023, 51 (1) 1-7; DOI: https://doi.org/10.1124/dmd.122.000945

  7. Weiss, Ashley

    1. Gut Microbiome–Wide Search for Bacterial Azoreductases Reveals Potentially Uncharacterized Azoreductases Encoded in the Human Gut Microbiome
      Domenick J. Braccia, Glory Minabou Ndjite, Ashley Weiss, Sophia Levy, Stephenie Abeysinghe, Xiaofang Jiang, Mihai Pop and Brantley Hall
      Drug Metabolism and Disposition January 2023, 51 (1) 142-153; DOI: https://doi.org/10.1124/dmd.122.000898

  8. Wu, Yali

    1. Covalent Binding Mechanism of Furmonertinib and Osimertinib With Human Serum Albumin
      Yali Wu, Lili Chen, Jian Chen, Hao Xue, Qingfeng He, Dafang Zhong and Xingxing Diao
      Drug Metabolism and Disposition January 2023, 51 (1) 8-16; DOI: https://doi.org/10.1124/dmd.122.001019

X

  1. Xue, Hao

    1. Covalent Binding Mechanism of Furmonertinib and Osimertinib With Human Serum Albumin
      Yali Wu, Lili Chen, Jian Chen, Hao Xue, Qingfeng He, Dafang Zhong and Xingxing Diao
      Drug Metabolism and Disposition January 2023, 51 (1) 8-16; DOI: https://doi.org/10.1124/dmd.122.001019

Y

  1. Yahara, Chizuko

    1. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver
      Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe and Kouichi Yoshinari
      Drug Metabolism and Disposition January 2023, 51 (1) 67-80; DOI: https://doi.org/10.1124/dmd.122.001000

  2. Yamazaki, Hiroshi

    1. A Comprehensive Investigation of Dog Cytochrome P450 3A (CYP3A) Reveals a Functional Role of Newly Identified CYP3A98 in Small Intestine
      A Comprehensive Investigation of Dog Cytochrome P450 3A (CYP3A) Reveals a Functional Role of Newly Identified CYP3A98 in Small Intestine
      Yasuhiro Uno, Shiori Jikuya, Yutaro Noda, Norie Murayama and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2023, 51 (1) 38-45; DOI: https://doi.org/10.1124/dmd.121.000749
    2. Species Specificity and Selection of Models for Drug Oxidations Mediated by Polymorphic Human Enzymes
      Species Specificity and Selection of Models for Drug Oxidations Mediated by Polymorphic Human Enzymes
      Hiroshi Yamazaki and Makiko Shimizu
      Drug Metabolism and Disposition January 2023, 51 (1) 123-129; DOI: https://doi.org/10.1124/dmd.121.000742

  3. Yoshinari, Kouichi

    1. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver
      Daigo Asano, Koichi Nakamura, Yumi Nishiya, Hideyuki Shiozawa, Hideo Takakusa, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Takakazu Hamada, Chizuko Yahara, Nobuaki Watanabe and Kouichi Yoshinari
      Drug Metabolism and Disposition January 2023, 51 (1) 67-80; DOI: https://doi.org/10.1124/dmd.122.001000

Z

  1. Zamboni, William C.

    1. COVID-19 Vaccines and the Virus: Impact on Drug Metabolism and Pharmacokinetics
      Eliza R. McColl, Maria A. Croyle, William C. Zamboni, William G. Honer, Mark Heise, Micheline Piquette-Miller and Kerry B. Goralski
      Drug Metabolism and Disposition January 2023, 51 (1) 130-141; DOI: https://doi.org/10.1124/dmd.122.000934

  2. Zhang, Qing-Yu

    1. Detection of Transgene Location in the CYP2A13/2B6/2F1-transgenic Mouse Model using Optical Genome Mapping Technology
      Xinxin Ding, John Han, Laura S. Van Winkle and Qing-Yu Zhang
      Drug Metabolism and Disposition January 2023, 51 (1) 46-53; DOI: https://doi.org/10.1124/dmd.122.001090

  3. Zhang, Zhengyu

    1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver
      Hiroyuki Ichida, Tatsuki Fukami, Keito Amai, Kohei Suzuki, Kenji Mishiro, Shiori Takano, Wataru Obuchi, Zhengyu Zhang, Akiko Watanabe, Masataka Nakano, Kengo Watanabe and Miki Nakajima
      Drug Metabolism and Disposition January 2023, 51 (1) 17-28; DOI: https://doi.org/10.1124/dmd.122.001037

  4. Zhong, Dafang

    1. Covalent Binding Mechanism of Furmonertinib and Osimertinib With Human Serum Albumin
      Yali Wu, Lili Chen, Jian Chen, Hao Xue, Qingfeng He, Dafang Zhong and Xingxing Diao
      Drug Metabolism and Disposition January 2023, 51 (1) 8-16; DOI: https://doi.org/10.1124/dmd.122.001019
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