Research ArticleArticle
Covalent Binding Mechanism of Furmonertinib and Osimertinib With Human Serum Albumin
Yali Wu, Lili Chen, Jian Chen, Hao Xue, Qingfeng He, Dafang Zhong and Xingxing Diao
Drug Metabolism and Disposition January 2023, 51 (1) 8-16; DOI: https://doi.org/10.1124/dmd.122.001019
Yali Wu
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.W., L.C., H.X., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.W., L.C., D.Z., X.D.); Radiopharmacy and Molecular Imaging Center (J.C.), and Department of Clinical Pharmacy and Pharmacy Administration (Q.H.), School of Pharmacy, Fudan University, Shanghai, China; and Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, Shanghai, China(J.C.)
Lili Chen
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.W., L.C., H.X., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.W., L.C., D.Z., X.D.); Radiopharmacy and Molecular Imaging Center (J.C.), and Department of Clinical Pharmacy and Pharmacy Administration (Q.H.), School of Pharmacy, Fudan University, Shanghai, China; and Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, Shanghai, China(J.C.)
Jian Chen
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.W., L.C., H.X., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.W., L.C., D.Z., X.D.); Radiopharmacy and Molecular Imaging Center (J.C.), and Department of Clinical Pharmacy and Pharmacy Administration (Q.H.), School of Pharmacy, Fudan University, Shanghai, China; and Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, Shanghai, China(J.C.)
Hao Xue
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.W., L.C., H.X., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.W., L.C., D.Z., X.D.); Radiopharmacy and Molecular Imaging Center (J.C.), and Department of Clinical Pharmacy and Pharmacy Administration (Q.H.), School of Pharmacy, Fudan University, Shanghai, China; and Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, Shanghai, China(J.C.)
Qingfeng He
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.W., L.C., H.X., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.W., L.C., D.Z., X.D.); Radiopharmacy and Molecular Imaging Center (J.C.), and Department of Clinical Pharmacy and Pharmacy Administration (Q.H.), School of Pharmacy, Fudan University, Shanghai, China; and Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, Shanghai, China(J.C.)
Dafang Zhong
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.W., L.C., H.X., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.W., L.C., D.Z., X.D.); Radiopharmacy and Molecular Imaging Center (J.C.), and Department of Clinical Pharmacy and Pharmacy Administration (Q.H.), School of Pharmacy, Fudan University, Shanghai, China; and Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, Shanghai, China(J.C.)
Xingxing Diao
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.W., L.C., H.X., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.W., L.C., D.Z., X.D.); Radiopharmacy and Molecular Imaging Center (J.C.), and Department of Clinical Pharmacy and Pharmacy Administration (Q.H.), School of Pharmacy, Fudan University, Shanghai, China; and Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, Shanghai, China(J.C.)
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Identification of TKI Covalent Adducts
Yali Wu, Lili Chen, Jian Chen, Hao Xue, Qingfeng He, Dafang Zhong and Xingxing Diao
Drug Metabolism and Disposition January 1, 2023, 51 (1) 8-16; DOI: https://doi.org/10.1124/dmd.122.001019
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