Index by author
October 01, 2023; Volume 51,Issue 10
A
Abraham, Trent L.
- You have accessImpact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4Luc R.A. Rougée, David W. Bedwell, Kasi Hansen, Trent L. Abraham and Stephen D. HallDrug Metabolism and Disposition October 2023, 51 (10) 1372-1380; DOI: https://doi.org/10.1124/dmd.123.001382
Achour, Brahim
- Open AccessNovel Approaches to Characterize Individual Drug Metabolism and Advance Precision MedicineKlarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. LathamDrug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066
Ahire, Deepak S.
- You have accessDissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of DrugsSandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat PrasadDrug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
Al-Sayah, Mohammad A.
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
B
Barbu, Ioana M.
- You have accessThe Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous AdministrationNarayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott ObachDrug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416
Bedwell, David W.
- You have accessImpact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4Luc R.A. Rougée, David W. Bedwell, Kasi Hansen, Trent L. Abraham and Stephen D. HallDrug Metabolism and Disposition October 2023, 51 (10) 1372-1380; DOI: https://doi.org/10.1124/dmd.123.001382
Beers, Jessica L.
- Open AccessNovel Approaches to Characterize Individual Drug Metabolism and Advance Precision MedicineKlarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. LathamDrug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066
Bobba, Sudheer
- You have accessIdentification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral AdministrationChenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu ZhangDrug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071
C
Chang, Jae H.
- You have accessAnalysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction StudiesMario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico ScheerDrug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398
Chen, Yu
- You have accessRecent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and MetabolomicsYu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang ZhengDrug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069
Cheruvu, Narayan
- You have accessThe Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous AdministrationNarayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott ObachDrug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416
Cho, Sungjoon
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
Choo, Edna F.
- You have accessIdentification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral AdministrationChenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu ZhangDrug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071
Chothe, Paresh P.
- You have accessAnalysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction StudiesMario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico ScheerDrug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398
Cronin, Ciarán N.
- You have accessDissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of DrugsSandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat PrasadDrug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
D
Dahlén, Anders
- Open AccessIn Vivo Metabolite Profiles of an N-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and HumansXue-Qing Li, Marie Elebring, Anders Dahlén and Lars WeidolfDrug Metabolism and Disposition October 2023, 51 (10) 1350-1361; DOI: https://doi.org/10.1124/dmd.123.001370
Dai, Wanying
- You have accessUse of Traditional and Proteomic Methods in the Assessment of a Preclinical Model of PreeclampsiaWanying Dai, Angela Pollinzi and Micheline Piquette-MillerDrug Metabolism and Disposition October 2023, 51 (10) 1308-1315; DOI: https://doi.org/10.1124/dmd.122.001080
Dai, Ziru
- You have accessFluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug InteractionsRongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo GeDrug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068
Dean, Brian
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
Deng, Yuzhong
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
Ding, Xinxin
- You have accessSpecial Section on New and Emerging Areas and Technologies in Drug Metabolism and Disposition, Part I–EditorialXiao-bo Zhong, Yurong Lai and Xinxin DingDrug Metabolism and Disposition October 2023, 51 (10) 1227-1229; DOI: https://doi.org/10.1124/dmd.123.001480
E
Elebring, Marie
- Open AccessIn Vivo Metabolite Profiles of an N-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and HumansXue-Qing Li, Marie Elebring, Anders Dahlén and Lars WeidolfDrug Metabolism and Disposition October 2023, 51 (10) 1350-1361; DOI: https://doi.org/10.1124/dmd.123.001370
F
Finel, Moshe
- You have accessFluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug InteractionsRongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo GeDrug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068
Foquet, Lander
- You have accessAnalysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction StudiesMario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico ScheerDrug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398
Fu, Tingting
- You have accessThe Important Role of Transporter Structures in Drug Disposition, Efficacy, and ToxicityTingting Fu, Su Zeng, Qingchuan Zheng and Feng ZhuDrug Metabolism and Disposition October 2023, 51 (10) 1316-1323; DOI: https://doi.org/10.1124/dmd.123.001275
Fukami, Tatsuki
- You have accessNEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 InductionRei Mitamura, Masataka Nakano, Motoki Isono, Kiamu Kurosawa, Tatsuki Fukami and Miki NakajimaDrug Metabolism and Disposition October 2023, 51 (10) 1230-1237; DOI: https://doi.org/10.1124/dmd.122.001065
G
Ge, Guangbo
- You have accessFluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug InteractionsRongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo GeDrug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068
Geffert, Raeanne M.
- Open AccessNovel Approaches to Characterize Individual Drug Metabolism and Advance Precision MedicineKlarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. LathamDrug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066
Goldman, Devorah C.
- You have accessAnalysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction StudiesMario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico ScheerDrug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398
Gu, Jingkai
- You have accessBioanalytical Assays for Pharmacokinetic and Biodistribution Study of Antibody-Drug ConjugatesLei Yin, Aiyun Xu, Yumeng Zhao and Jingkai GuDrug Metabolism and Disposition October 2023, 51 (10) 1324-1331; DOI: https://doi.org/10.1124/dmd.123.001313
H
Hall, Stephen D.
- You have accessImpact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4Luc R.A. Rougée, David W. Bedwell, Kasi Hansen, Trent L. Abraham and Stephen D. HallDrug Metabolism and Disposition October 2023, 51 (10) 1372-1380; DOI: https://doi.org/10.1124/dmd.123.001382
Hansen, Kasi
- You have accessImpact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4Luc R.A. Rougée, David W. Bedwell, Kasi Hansen, Trent L. Abraham and Stephen D. HallDrug Metabolism and Disposition October 2023, 51 (10) 1372-1380; DOI: https://doi.org/10.1124/dmd.123.001382
He, Rongjing
- You have accessFluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug InteractionsRongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo GeDrug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068
He, Yan
- You have accessRecent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and MetabolomicsYu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang ZhengDrug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069
Heikkinen, Aki T.
- You have accessAnalysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction StudiesMario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico ScheerDrug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398
Heyward, Scott
- You have accessDissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of DrugsSandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat PrasadDrug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
Ho, Quynh
- You have accessIdentification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral AdministrationChenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu ZhangDrug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071
Hoffmann, Matthew
- You have accessAnalysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction StudiesMario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico ScheerDrug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398
I
Imai, Shunji
- You have accessPrediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using ViltolarsenShunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi KusanoDrug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425
Ishida, Kazuya
- You have accessInterpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein ComplexMengyue Yin, Kazuya Ishida, Xiaomin Liang, Yurong Lai and Jashvant D. UnadkatDrug Metabolism and Disposition October 2023, 51 (10) 1381-1390; DOI: https://doi.org/10.1124/dmd.123.001386
Isono, Motoki
- You have accessNEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 InductionRei Mitamura, Masataka Nakano, Motoki Isono, Kiamu Kurosawa, Tatsuki Fukami and Miki NakajimaDrug Metabolism and Disposition October 2023, 51 (10) 1230-1237; DOI: https://doi.org/10.1124/dmd.122.001065
J
Jackson, Klarissa D.
- Open AccessNovel Approaches to Characterize Individual Drug Metabolism and Advance Precision MedicineKlarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. LathamDrug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066
Jones, Rhys M.
- You have accessThe Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous AdministrationNarayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott ObachDrug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416
Jones, Robert S.
- You have accessDissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of DrugsSandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat PrasadDrug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
- You have accessAnalysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction StudiesMario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico ScheerDrug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398
Jorski, Jamie D.
- You have accessIdentification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral AdministrationChenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu ZhangDrug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071
Jusko, William J.
- You have accessUtility of Minimal Physiologically Based Pharmacokinetic Models for Assessing Fractional Distribution, Oral Absorption, and Series-Compartment Models of Hepatic ClearanceXiaonan Li and William J. JuskoDrug Metabolism and Disposition October 2023, 51 (10) 1403-1418; DOI: https://doi.org/10.1124/dmd.123.001403
K
Kenny, Jane R.
- You have accessIdentification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral AdministrationChenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu ZhangDrug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071
Khojasteh, S. Cyrus
- You have accessDissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of DrugsSandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat PrasadDrug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
- You have accessIdentification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral AdministrationChenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu ZhangDrug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071
Kshirsagar, Smita
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
Kulkarni, Priyanka
- You have accessDissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of DrugsSandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat PrasadDrug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
Kurosawa, Kiamu
- You have accessNEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 InductionRei Mitamura, Masataka Nakano, Motoki Isono, Kiamu Kurosawa, Tatsuki Fukami and Miki NakajimaDrug Metabolism and Disposition October 2023, 51 (10) 1230-1237; DOI: https://doi.org/10.1124/dmd.122.001065
Kusano, Kazutomi
- You have accessPrediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using ViltolarsenShunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi KusanoDrug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425
L
Lai, Yurong
- You have accessSpecial Section on New and Emerging Areas and Technologies in Drug Metabolism and Disposition, Part I–EditorialXiao-bo Zhong, Yurong Lai and Xinxin DingDrug Metabolism and Disposition October 2023, 51 (10) 1227-1229; DOI: https://doi.org/10.1124/dmd.123.001480
- You have accessInterpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein ComplexMengyue Yin, Kazuya Ishida, Xiaomin Liang, Yurong Lai and Jashvant D. UnadkatDrug Metabolism and Disposition October 2023, 51 (10) 1381-1390; DOI: https://doi.org/10.1124/dmd.123.001386
Latham, Bethany D.
- Open AccessNovel Approaches to Characterize Individual Drug Metabolism and Advance Precision MedicineKlarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. LathamDrug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066
Lee, Jonghwa
- Open AccessNovel Approaches to Characterize Individual Drug Metabolism and Advance Precision MedicineKlarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. LathamDrug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066
Li, Weiwei
- You have accessRecent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and MetabolomicsYu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang ZhengDrug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069
Li, Xiaonan
- You have accessUtility of Minimal Physiologically Based Pharmacokinetic Models for Assessing Fractional Distribution, Oral Absorption, and Series-Compartment Models of Hepatic ClearanceXiaonan Li and William J. JuskoDrug Metabolism and Disposition October 2023, 51 (10) 1403-1418; DOI: https://doi.org/10.1124/dmd.123.001403
Li, Ximei
- You have accessRecent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and MetabolomicsYu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang ZhengDrug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069
Li, Xue-Qing
- Open AccessIn Vivo Metabolite Profiles of an N-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and HumansXue-Qing Li, Marie Elebring, Anders Dahlén and Lars WeidolfDrug Metabolism and Disposition October 2023, 51 (10) 1350-1361; DOI: https://doi.org/10.1124/dmd.123.001370
Liang, Xiaomin
- You have accessInterpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein ComplexMengyue Yin, Kazuya Ishida, Xiaomin Liang, Yurong Lai and Jashvant D. UnadkatDrug Metabolism and Disposition October 2023, 51 (10) 1381-1390; DOI: https://doi.org/10.1124/dmd.123.001386
Liederer, Bianca M.
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
Liu, Lichuan
- You have accessIdentification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral AdministrationChenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu ZhangDrug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071
Liu, Ying
- You have accessRecent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and MetabolomicsYu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang ZhengDrug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069
M
Ma, Shuguang
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
Malhi, Vikram
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
Mannila, Janne
- You have accessAnalysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction StudiesMario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico ScheerDrug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398
Mezler, Mario
- You have accessAnalysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction StudiesMario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico ScheerDrug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398
Mitamura, Rei
- You have accessNEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 InductionRei Mitamura, Masataka Nakano, Motoki Isono, Kiamu Kurosawa, Tatsuki Fukami and Miki NakajimaDrug Metabolism and Disposition October 2023, 51 (10) 1230-1237; DOI: https://doi.org/10.1124/dmd.122.001065
Mori, Jumpei
- You have accessPrediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using ViltolarsenShunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi KusanoDrug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425
Murray, Bernard P.
- You have accessDissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of DrugsSandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat PrasadDrug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
Murray, John W.
- You have accessInteraction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma MembranePijun Wang, John W. Murray and Allan W. WolkoffDrug Metabolism and Disposition October 2023, 51 (10) 1342-1349; DOI: https://doi.org/10.1124/dmd.123.001248
Musib, Luna
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
N
Nakajima, Miki
- You have accessNEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 InductionRei Mitamura, Masataka Nakano, Motoki Isono, Kiamu Kurosawa, Tatsuki Fukami and Miki NakajimaDrug Metabolism and Disposition October 2023, 51 (10) 1230-1237; DOI: https://doi.org/10.1124/dmd.122.001065
Nakano, Masataka
- You have accessNEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 InductionRei Mitamura, Masataka Nakano, Motoki Isono, Kiamu Kurosawa, Tatsuki Fukami and Miki NakajimaDrug Metabolism and Disposition October 2023, 51 (10) 1230-1237; DOI: https://doi.org/10.1124/dmd.122.001065
Nugteren, James
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
O
Obach, R. Scott
- You have accessThe Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous AdministrationNarayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott ObachDrug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416
P
Peng, Ying
- You have accessRecent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and MetabolomicsYu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang ZhengDrug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069
Pikuleva, Irina A.
- Open AccessChallenges and Opportunities in P450 Research on the EyeIrina A. PikulevaDrug Metabolism and Disposition October 2023, 51 (10) 1295-1307; DOI: https://doi.org/10.1124/dmd.122.001072
Piquette-Miller, Micheline
- You have accessUse of Traditional and Proteomic Methods in the Assessment of a Preclinical Model of PreeclampsiaWanying Dai, Angela Pollinzi and Micheline Piquette-MillerDrug Metabolism and Disposition October 2023, 51 (10) 1308-1315; DOI: https://doi.org/10.1124/dmd.122.001080
Pollinzi, Angela
- You have accessUse of Traditional and Proteomic Methods in the Assessment of a Preclinical Model of PreeclampsiaWanying Dai, Angela Pollinzi and Micheline Piquette-MillerDrug Metabolism and Disposition October 2023, 51 (10) 1308-1315; DOI: https://doi.org/10.1124/dmd.122.001080
Prasad, Bhagwat
- You have accessDissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of DrugsSandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat PrasadDrug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
Pusalkar, Sandeepraj
- You have accessAnalysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction StudiesMario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico ScheerDrug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398
R
Rougée, Luc R.A.
- You have accessImpact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4Luc R.A. Rougée, David W. Bedwell, Kasi Hansen, Trent L. Abraham and Stephen D. HallDrug Metabolism and Disposition October 2023, 51 (10) 1372-1380; DOI: https://doi.org/10.1124/dmd.123.001382
S
Sane, Rucha
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
Sangaraju, Dewakar
- You have accessAnalysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction StudiesMario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico ScheerDrug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398
Sasaki, Yoshihiro
- You have accessPrediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using ViltolarsenShunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi KusanoDrug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425
Scheer, Nico
- You have accessAnalysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction StudiesMario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico ScheerDrug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398
Schildknegt, Klaas
- You have accessThe Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous AdministrationNarayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott ObachDrug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416
Singh, Dilip K.
- You have accessDissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of DrugsSandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat PrasadDrug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
Smith, Bill J.
- You have accessDissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of DrugsSandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat PrasadDrug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
Spigt, Pieter A.
- You have accessThe Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous AdministrationNarayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott ObachDrug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416
Su, Dian
- You have accessIdentification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral AdministrationChenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu ZhangDrug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071
Subash, Sandhya
- You have accessDissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of DrugsSandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat PrasadDrug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
Suda, Yusuke
- You have accessPrediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using ViltolarsenShunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi KusanoDrug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425
T
Takahashi, Ryan H.
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
Toussi, Sima S.
- You have accessThe Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous AdministrationNarayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott ObachDrug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416
Tu, Dongzhu
- You have accessFluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug InteractionsRongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo GeDrug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068
U
Unadkat, Jashvant D.
- You have accessInterpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein ComplexMengyue Yin, Kazuya Ishida, Xiaomin Liang, Yurong Lai and Jashvant D. UnadkatDrug Metabolism and Disposition October 2023, 51 (10) 1381-1390; DOI: https://doi.org/10.1124/dmd.123.001386
V
van Duijn, Esther
- You have accessThe Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous AdministrationNarayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott ObachDrug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416
W
Wang, Jing
- You have accessIdentification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral AdministrationChenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu ZhangDrug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071
Wang, Pijun
- You have accessInteraction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma MembranePijun Wang, John W. Murray and Allan W. WolkoffDrug Metabolism and Disposition October 2023, 51 (10) 1342-1349; DOI: https://doi.org/10.1124/dmd.123.001248
Weidolf, Lars
- Open AccessIn Vivo Metabolite Profiles of an N-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and HumansXue-Qing Li, Marie Elebring, Anders Dahlén and Lars WeidolfDrug Metabolism and Disposition October 2023, 51 (10) 1350-1361; DOI: https://doi.org/10.1124/dmd.123.001370
Wolkoff, Allan W.
- You have accessInteraction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma MembranePijun Wang, John W. Murray and Allan W. WolkoffDrug Metabolism and Disposition October 2023, 51 (10) 1342-1349; DOI: https://doi.org/10.1124/dmd.123.001248
X
Xu, Aiyun
- You have accessBioanalytical Assays for Pharmacokinetic and Biodistribution Study of Antibody-Drug ConjugatesLei Yin, Aiyun Xu, Yumeng Zhao and Jingkai GuDrug Metabolism and Disposition October 2023, 51 (10) 1324-1331; DOI: https://doi.org/10.1124/dmd.123.001313
Y
Yamada, Tetsuhiro
- You have accessPrediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using ViltolarsenShunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi KusanoDrug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425
Yang, Ling
- You have accessFluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug InteractionsRongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo GeDrug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068
Yin, Lei
- You have accessBioanalytical Assays for Pharmacokinetic and Biodistribution Study of Antibody-Drug ConjugatesLei Yin, Aiyun Xu, Yumeng Zhao and Jingkai GuDrug Metabolism and Disposition October 2023, 51 (10) 1324-1331; DOI: https://doi.org/10.1124/dmd.123.001313
Yin, Mengyue
- You have accessInterpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein ComplexMengyue Yin, Kazuya Ishida, Xiaomin Liang, Yurong Lai and Jashvant D. UnadkatDrug Metabolism and Disposition October 2023, 51 (10) 1381-1390; DOI: https://doi.org/10.1124/dmd.123.001386
Yost, Edward
- You have accessThe Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) InhibitorRyan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna MusibDrug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175
Z
Zeng, Su
- You have accessThe Important Role of Transporter Structures in Drug Disposition, Efficacy, and ToxicityTingting Fu, Su Zeng, Qingchuan Zheng and Feng ZhuDrug Metabolism and Disposition October 2023, 51 (10) 1316-1323; DOI: https://doi.org/10.1124/dmd.123.001275
Zhang, Chenghong
- You have accessIdentification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral AdministrationChenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu ZhangDrug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071
Zhang, Donglu
- You have accessIdentification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral AdministrationChenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu ZhangDrug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071
Zhang, Feng
- You have accessFluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug InteractionsRongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo GeDrug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068
Zhao, Yumeng
- You have accessBioanalytical Assays for Pharmacokinetic and Biodistribution Study of Antibody-Drug ConjugatesLei Yin, Aiyun Xu, Yumeng Zhao and Jingkai GuDrug Metabolism and Disposition October 2023, 51 (10) 1324-1331; DOI: https://doi.org/10.1124/dmd.123.001313
Zheng, Jiang
- You have accessRecent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and MetabolomicsYu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang ZhengDrug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069
Zheng, Qingchuan
- You have accessThe Important Role of Transporter Structures in Drug Disposition, Efficacy, and ToxicityTingting Fu, Su Zeng, Qingchuan Zheng and Feng ZhuDrug Metabolism and Disposition October 2023, 51 (10) 1316-1323; DOI: https://doi.org/10.1124/dmd.123.001275
Zhong, Xiao-bo
- You have accessSpecial Section on New and Emerging Areas and Technologies in Drug Metabolism and Disposition, Part I–EditorialXiao-bo Zhong, Yurong Lai and Xinxin DingDrug Metabolism and Disposition October 2023, 51 (10) 1227-1229; DOI: https://doi.org/10.1124/dmd.123.001480
Zhu, Feng
- You have accessThe Important Role of Transporter Structures in Drug Disposition, Efficacy, and ToxicityTingting Fu, Su Zeng, Qingchuan Zheng and Feng ZhuDrug Metabolism and Disposition October 2023, 51 (10) 1316-1323; DOI: https://doi.org/10.1124/dmd.123.001275
Zientek, Michael A.
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