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Index by author

October 01, 2023; Volume 51,Issue 10

A

  1. Abraham, Trent L.

    1. Impact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4
      Luc R.A. Rougée, David W. Bedwell, Kasi Hansen, Trent L. Abraham and Stephen D. Hall
      Drug Metabolism and Disposition October 2023, 51 (10) 1372-1380; DOI: https://doi.org/10.1124/dmd.123.001382

  2. Achour, Brahim

    1. Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
      Open Access
      Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
      Klarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. Latham
      Drug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066

  3. Ahire, Deepak S.

    1. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
      Sandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat Prasad
      Drug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379

  4. Al-Sayah, Mohammad A.

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

B

  1. Barbu, Ioana M.

    1. The Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous Administration
      Narayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott Obach
      Drug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416

  2. Bedwell, David W.

    1. Impact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4
      Luc R.A. Rougée, David W. Bedwell, Kasi Hansen, Trent L. Abraham and Stephen D. Hall
      Drug Metabolism and Disposition October 2023, 51 (10) 1372-1380; DOI: https://doi.org/10.1124/dmd.123.001382

  3. Beers, Jessica L.

    1. Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
      Open Access
      Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
      Klarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. Latham
      Drug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066

  4. Bobba, Sudheer

    1. Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Chenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu Zhang
      Drug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071

C

  1. Chang, Jae H.

    1. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies
      Mario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico Scheer
      Drug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398

  2. Chen, Yu

    1. Recent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and Metabolomics
      Yu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069

  3. Cheruvu, Narayan

    1. The Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous Administration
      Narayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott Obach
      Drug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416

  4. Cho, Sungjoon

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

  5. Choo, Edna F.

    1. Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Chenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu Zhang
      Drug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071

  6. Chothe, Paresh P.

    1. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies
      Mario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico Scheer
      Drug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398

  7. Cronin, Ciarán N.

    1. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
      Sandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat Prasad
      Drug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379

D

  1. Dahlén, Anders

    1. In Vivo Metabolite Profiles of an <em>N</em>-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and Humans
      Open Access
      In Vivo Metabolite Profiles of an N-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and Humans
      Xue-Qing Li, Marie Elebring, Anders Dahlén and Lars Weidolf
      Drug Metabolism and Disposition October 2023, 51 (10) 1350-1361; DOI: https://doi.org/10.1124/dmd.123.001370

  2. Dai, Wanying

    1. Use of Traditional and Proteomic Methods in the Assessment of a Preclinical Model of Preeclampsia
      Wanying Dai, Angela Pollinzi and Micheline Piquette-Miller
      Drug Metabolism and Disposition October 2023, 51 (10) 1308-1315; DOI: https://doi.org/10.1124/dmd.122.001080

  3. Dai, Ziru

    1. Fluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug Interactions
      Rongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo Ge
      Drug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068

  4. Dean, Brian

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

  5. Deng, Yuzhong

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

  6. Ding, Xinxin

    1. Special Section on New and Emerging Areas and Technologies in Drug Metabolism and Disposition, Part I–Editorial
      Xiao-bo Zhong, Yurong Lai and Xinxin Ding
      Drug Metabolism and Disposition October 2023, 51 (10) 1227-1229; DOI: https://doi.org/10.1124/dmd.123.001480

E

  1. Elebring, Marie

    1. In Vivo Metabolite Profiles of an <em>N</em>-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and Humans
      Open Access
      In Vivo Metabolite Profiles of an N-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and Humans
      Xue-Qing Li, Marie Elebring, Anders Dahlén and Lars Weidolf
      Drug Metabolism and Disposition October 2023, 51 (10) 1350-1361; DOI: https://doi.org/10.1124/dmd.123.001370

F

  1. Finel, Moshe

    1. Fluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug Interactions
      Rongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo Ge
      Drug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068

  2. Foquet, Lander

    1. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies
      Mario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico Scheer
      Drug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398

  3. Fu, Tingting

    1. The Important Role of Transporter Structures in Drug Disposition, Efficacy, and Toxicity
      The Important Role of Transporter Structures in Drug Disposition, Efficacy, and Toxicity
      Tingting Fu, Su Zeng, Qingchuan Zheng and Feng Zhu
      Drug Metabolism and Disposition October 2023, 51 (10) 1316-1323; DOI: https://doi.org/10.1124/dmd.123.001275

  4. Fukami, Tatsuki

    1. NEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 Induction
      Rei Mitamura, Masataka Nakano, Motoki Isono, Kiamu Kurosawa, Tatsuki Fukami and Miki Nakajima
      Drug Metabolism and Disposition October 2023, 51 (10) 1230-1237; DOI: https://doi.org/10.1124/dmd.122.001065

G

  1. Ge, Guangbo

    1. Fluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug Interactions
      Rongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo Ge
      Drug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068

  2. Geffert, Raeanne M.

    1. Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
      Open Access
      Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
      Klarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. Latham
      Drug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066

  3. Goldman, Devorah C.

    1. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies
      Mario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico Scheer
      Drug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398

  4. Gu, Jingkai

    1. Bioanalytical Assays for Pharmacokinetic and Biodistribution Study of Antibody-Drug Conjugates
      Lei Yin, Aiyun Xu, Yumeng Zhao and Jingkai Gu
      Drug Metabolism and Disposition October 2023, 51 (10) 1324-1331; DOI: https://doi.org/10.1124/dmd.123.001313

H

  1. Hall, Stephen D.

    1. Impact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4
      Luc R.A. Rougée, David W. Bedwell, Kasi Hansen, Trent L. Abraham and Stephen D. Hall
      Drug Metabolism and Disposition October 2023, 51 (10) 1372-1380; DOI: https://doi.org/10.1124/dmd.123.001382

  2. Hansen, Kasi

    1. Impact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4
      Luc R.A. Rougée, David W. Bedwell, Kasi Hansen, Trent L. Abraham and Stephen D. Hall
      Drug Metabolism and Disposition October 2023, 51 (10) 1372-1380; DOI: https://doi.org/10.1124/dmd.123.001382

  3. He, Rongjing

    1. Fluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug Interactions
      Rongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo Ge
      Drug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068

  4. He, Yan

    1. Recent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and Metabolomics
      Yu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069

  5. Heikkinen, Aki T.

    1. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies
      Mario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico Scheer
      Drug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398

  6. Heyward, Scott

    1. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
      Sandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat Prasad
      Drug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379

  7. Ho, Quynh

    1. Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Chenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu Zhang
      Drug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071

  8. Hoffmann, Matthew

    1. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies
      Mario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico Scheer
      Drug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398

I

  1. Imai, Shunji

    1. Prediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using Viltolarsen
      Shunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi Kusano
      Drug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425

  2. Ishida, Kazuya

    1. Interpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein Complex
      Interpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein Complex
      Mengyue Yin, Kazuya Ishida, Xiaomin Liang, Yurong Lai and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2023, 51 (10) 1381-1390; DOI: https://doi.org/10.1124/dmd.123.001386

  3. Isono, Motoki

    1. NEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 Induction
      Rei Mitamura, Masataka Nakano, Motoki Isono, Kiamu Kurosawa, Tatsuki Fukami and Miki Nakajima
      Drug Metabolism and Disposition October 2023, 51 (10) 1230-1237; DOI: https://doi.org/10.1124/dmd.122.001065

J

  1. Jackson, Klarissa D.

    1. Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
      Open Access
      Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
      Klarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. Latham
      Drug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066

  2. Jones, Rhys M.

    1. The Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous Administration
      Narayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott Obach
      Drug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416

  3. Jones, Robert S.

    1. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
      Sandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat Prasad
      Drug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
    2. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies
      Mario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico Scheer
      Drug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398

  4. Jorski, Jamie D.

    1. Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Chenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu Zhang
      Drug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071

  5. Jusko, William J.

    1. Utility of Minimal Physiologically Based Pharmacokinetic Models for Assessing Fractional Distribution, Oral Absorption, and Series-Compartment Models of Hepatic Clearance
      Utility of Minimal Physiologically Based Pharmacokinetic Models for Assessing Fractional Distribution, Oral Absorption, and Series-Compartment Models of Hepatic Clearance
      Xiaonan Li and William J. Jusko
      Drug Metabolism and Disposition October 2023, 51 (10) 1403-1418; DOI: https://doi.org/10.1124/dmd.123.001403

K

  1. Kenny, Jane R.

    1. Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Chenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu Zhang
      Drug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071

  2. Khojasteh, S. Cyrus

    1. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
      Sandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat Prasad
      Drug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
    2. Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Chenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu Zhang
      Drug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071

  3. Kshirsagar, Smita

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

  4. Kulkarni, Priyanka

    1. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
      Sandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat Prasad
      Drug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379

  5. Kurosawa, Kiamu

    1. NEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 Induction
      Rei Mitamura, Masataka Nakano, Motoki Isono, Kiamu Kurosawa, Tatsuki Fukami and Miki Nakajima
      Drug Metabolism and Disposition October 2023, 51 (10) 1230-1237; DOI: https://doi.org/10.1124/dmd.122.001065

  6. Kusano, Kazutomi

    1. Prediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using Viltolarsen
      Shunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi Kusano
      Drug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425

L

  1. Lai, Yurong

    1. Special Section on New and Emerging Areas and Technologies in Drug Metabolism and Disposition, Part I–Editorial
      Xiao-bo Zhong, Yurong Lai and Xinxin Ding
      Drug Metabolism and Disposition October 2023, 51 (10) 1227-1229; DOI: https://doi.org/10.1124/dmd.123.001480
    2. Interpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein Complex
      Interpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein Complex
      Mengyue Yin, Kazuya Ishida, Xiaomin Liang, Yurong Lai and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2023, 51 (10) 1381-1390; DOI: https://doi.org/10.1124/dmd.123.001386

  2. Latham, Bethany D.

    1. Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
      Open Access
      Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
      Klarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. Latham
      Drug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066

  3. Lee, Jonghwa

    1. Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
      Open Access
      Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
      Klarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. Latham
      Drug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066

  4. Li, Weiwei

    1. Recent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and Metabolomics
      Yu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069

  5. Li, Xiaonan

    1. Utility of Minimal Physiologically Based Pharmacokinetic Models for Assessing Fractional Distribution, Oral Absorption, and Series-Compartment Models of Hepatic Clearance
      Utility of Minimal Physiologically Based Pharmacokinetic Models for Assessing Fractional Distribution, Oral Absorption, and Series-Compartment Models of Hepatic Clearance
      Xiaonan Li and William J. Jusko
      Drug Metabolism and Disposition October 2023, 51 (10) 1403-1418; DOI: https://doi.org/10.1124/dmd.123.001403

  6. Li, Ximei

    1. Recent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and Metabolomics
      Yu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069

  7. Li, Xue-Qing

    1. In Vivo Metabolite Profiles of an <em>N</em>-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and Humans
      Open Access
      In Vivo Metabolite Profiles of an N-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and Humans
      Xue-Qing Li, Marie Elebring, Anders Dahlén and Lars Weidolf
      Drug Metabolism and Disposition October 2023, 51 (10) 1350-1361; DOI: https://doi.org/10.1124/dmd.123.001370

  8. Liang, Xiaomin

    1. Interpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein Complex
      Interpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein Complex
      Mengyue Yin, Kazuya Ishida, Xiaomin Liang, Yurong Lai and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2023, 51 (10) 1381-1390; DOI: https://doi.org/10.1124/dmd.123.001386

  9. Liederer, Bianca M.

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

  10. Liu, Lichuan

    1. Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Chenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu Zhang
      Drug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071

  11. Liu, Ying

    1. Recent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and Metabolomics
      Yu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069

M

  1. Ma, Shuguang

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

  2. Malhi, Vikram

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

  3. Mannila, Janne

    1. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies
      Mario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico Scheer
      Drug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398

  4. Mezler, Mario

    1. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies
      Mario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico Scheer
      Drug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398

  5. Mitamura, Rei

    1. NEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 Induction
      Rei Mitamura, Masataka Nakano, Motoki Isono, Kiamu Kurosawa, Tatsuki Fukami and Miki Nakajima
      Drug Metabolism and Disposition October 2023, 51 (10) 1230-1237; DOI: https://doi.org/10.1124/dmd.122.001065

  6. Mori, Jumpei

    1. Prediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using Viltolarsen
      Shunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi Kusano
      Drug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425

  7. Murray, Bernard P.

    1. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
      Sandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat Prasad
      Drug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379

  8. Murray, John W.

    1. Interaction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma Membrane
      Interaction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma Membrane
      Pijun Wang, John W. Murray and Allan W. Wolkoff
      Drug Metabolism and Disposition October 2023, 51 (10) 1342-1349; DOI: https://doi.org/10.1124/dmd.123.001248

  9. Musib, Luna

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

N

  1. Nakajima, Miki

    1. NEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 Induction
      Rei Mitamura, Masataka Nakano, Motoki Isono, Kiamu Kurosawa, Tatsuki Fukami and Miki Nakajima
      Drug Metabolism and Disposition October 2023, 51 (10) 1230-1237; DOI: https://doi.org/10.1124/dmd.122.001065

  2. Nakano, Masataka

    1. NEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 Induction
      Rei Mitamura, Masataka Nakano, Motoki Isono, Kiamu Kurosawa, Tatsuki Fukami and Miki Nakajima
      Drug Metabolism and Disposition October 2023, 51 (10) 1230-1237; DOI: https://doi.org/10.1124/dmd.122.001065

  3. Nugteren, James

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

O

  1. Obach, R. Scott

    1. The Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous Administration
      Narayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott Obach
      Drug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416

P

  1. Peng, Ying

    1. Recent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and Metabolomics
      Yu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069

  2. Pikuleva, Irina A.

    1. Open Access
      Challenges and Opportunities in P450 Research on the Eye
      Irina A. Pikuleva
      Drug Metabolism and Disposition October 2023, 51 (10) 1295-1307; DOI: https://doi.org/10.1124/dmd.122.001072

  3. Piquette-Miller, Micheline

    1. Use of Traditional and Proteomic Methods in the Assessment of a Preclinical Model of Preeclampsia
      Wanying Dai, Angela Pollinzi and Micheline Piquette-Miller
      Drug Metabolism and Disposition October 2023, 51 (10) 1308-1315; DOI: https://doi.org/10.1124/dmd.122.001080

  4. Pollinzi, Angela

    1. Use of Traditional and Proteomic Methods in the Assessment of a Preclinical Model of Preeclampsia
      Wanying Dai, Angela Pollinzi and Micheline Piquette-Miller
      Drug Metabolism and Disposition October 2023, 51 (10) 1308-1315; DOI: https://doi.org/10.1124/dmd.122.001080

  5. Prasad, Bhagwat

    1. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
      Sandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat Prasad
      Drug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379

  6. Pusalkar, Sandeepraj

    1. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies
      Mario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico Scheer
      Drug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398

R

  1. Rougée, Luc R.A.

    1. Impact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4
      Luc R.A. Rougée, David W. Bedwell, Kasi Hansen, Trent L. Abraham and Stephen D. Hall
      Drug Metabolism and Disposition October 2023, 51 (10) 1372-1380; DOI: https://doi.org/10.1124/dmd.123.001382

S

  1. Sane, Rucha

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

  2. Sangaraju, Dewakar

    1. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies
      Mario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico Scheer
      Drug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398

  3. Sasaki, Yoshihiro

    1. Prediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using Viltolarsen
      Shunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi Kusano
      Drug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425

  4. Scheer, Nico

    1. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies
      Mario Mezler, Robert S. Jones, Dewakar Sangaraju, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae H. Chang, Lander Foquet, Sandeepraj Pusalkar, Paresh P. Chothe and Nico Scheer
      Drug Metabolism and Disposition October 2023, 51 (10) 1391-1402; DOI: https://doi.org/10.1124/dmd.123.001398

  5. Schildknegt, Klaas

    1. The Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous Administration
      Narayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott Obach
      Drug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416

  6. Singh, Dilip K.

    1. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
      Sandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat Prasad
      Drug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379

  7. Smith, Bill J.

    1. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
      Sandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat Prasad
      Drug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379

  8. Spigt, Pieter A.

    1. The Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous Administration
      Narayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott Obach
      Drug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416

  9. Su, Dian

    1. Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Chenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu Zhang
      Drug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071

  10. Subash, Sandhya

    1. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
      Sandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat Prasad
      Drug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379

  11. Suda, Yusuke

    1. Prediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using Viltolarsen
      Shunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi Kusano
      Drug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425

T

  1. Takahashi, Ryan H.

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

  2. Toussi, Sima S.

    1. The Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous Administration
      Narayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott Obach
      Drug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416

  3. Tu, Dongzhu

    1. Fluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug Interactions
      Rongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo Ge
      Drug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068

U

  1. Unadkat, Jashvant D.

    1. Interpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein Complex
      Interpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein Complex
      Mengyue Yin, Kazuya Ishida, Xiaomin Liang, Yurong Lai and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2023, 51 (10) 1381-1390; DOI: https://doi.org/10.1124/dmd.123.001386

V

  1. van Duijn, Esther

    1. The Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous Administration
      Narayan Cheruvu, Esther van Duijn, Pieter A. Spigt, Ioana M. Barbu, Sima S. Toussi, Klaas Schildknegt, Rhys M. Jones and R. Scott Obach
      Drug Metabolism and Disposition October 2023, 51 (10) 1419-1427; DOI: https://doi.org/10.1124/dmd.123.001416

W

  1. Wang, Jing

    1. Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Chenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu Zhang
      Drug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071

  2. Wang, Pijun

    1. Interaction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma Membrane
      Interaction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma Membrane
      Pijun Wang, John W. Murray and Allan W. Wolkoff
      Drug Metabolism and Disposition October 2023, 51 (10) 1342-1349; DOI: https://doi.org/10.1124/dmd.123.001248

  3. Weidolf, Lars

    1. In Vivo Metabolite Profiles of an <em>N</em>-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and Humans
      Open Access
      In Vivo Metabolite Profiles of an N-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and Humans
      Xue-Qing Li, Marie Elebring, Anders Dahlén and Lars Weidolf
      Drug Metabolism and Disposition October 2023, 51 (10) 1350-1361; DOI: https://doi.org/10.1124/dmd.123.001370

  4. Wolkoff, Allan W.

    1. Interaction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma Membrane
      Interaction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma Membrane
      Pijun Wang, John W. Murray and Allan W. Wolkoff
      Drug Metabolism and Disposition October 2023, 51 (10) 1342-1349; DOI: https://doi.org/10.1124/dmd.123.001248

X

  1. Xu, Aiyun

    1. Bioanalytical Assays for Pharmacokinetic and Biodistribution Study of Antibody-Drug Conjugates
      Lei Yin, Aiyun Xu, Yumeng Zhao and Jingkai Gu
      Drug Metabolism and Disposition October 2023, 51 (10) 1324-1331; DOI: https://doi.org/10.1124/dmd.123.001313

Y

  1. Yamada, Tetsuhiro

    1. Prediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using Viltolarsen
      Shunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi Kusano
      Drug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425

  2. Yang, Ling

    1. Fluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug Interactions
      Rongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo Ge
      Drug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068

  3. Yin, Lei

    1. Bioanalytical Assays for Pharmacokinetic and Biodistribution Study of Antibody-Drug Conjugates
      Lei Yin, Aiyun Xu, Yumeng Zhao and Jingkai Gu
      Drug Metabolism and Disposition October 2023, 51 (10) 1324-1331; DOI: https://doi.org/10.1124/dmd.123.001313

  4. Yin, Mengyue

    1. Interpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein Complex
      Interpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein Complex
      Mengyue Yin, Kazuya Ishida, Xiaomin Liang, Yurong Lai and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2023, 51 (10) 1381-1390; DOI: https://doi.org/10.1124/dmd.123.001386

  5. Yost, Edward

    1. The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor
      Ryan H. Takahashi, Vikram Malhi, Bianca M. Liederer, Sungjoon Cho, Yuzhong Deng, Brian Dean, James Nugteren, Edward Yost, Mohammad A. Al-Sayah, Rucha Sane, Smita Kshirsagar, Shuguang Ma and Luna Musib
      Drug Metabolism and Disposition October 2023, 51 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.001175

Z

  1. Zeng, Su

    1. The Important Role of Transporter Structures in Drug Disposition, Efficacy, and Toxicity
      The Important Role of Transporter Structures in Drug Disposition, Efficacy, and Toxicity
      Tingting Fu, Su Zeng, Qingchuan Zheng and Feng Zhu
      Drug Metabolism and Disposition October 2023, 51 (10) 1316-1323; DOI: https://doi.org/10.1124/dmd.123.001275

  2. Zhang, Chenghong

    1. Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Chenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu Zhang
      Drug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071

  3. Zhang, Donglu

    1. Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration
      Chenghong Zhang, Dian Su, Edna F. Choo, Lichuan Liu, Sudheer Bobba, Jamie D. Jorski, Quynh Ho, Jing Wang, Jane R. Kenny, S. Cyrus Khojasteh and Donglu Zhang
      Drug Metabolism and Disposition October 2023, 51 (10) 1284-1294; DOI: https://doi.org/10.1124/dmd.122.001071

  4. Zhang, Feng

    1. Fluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug–Drug Interactions
      Rongjing He, Ziru Dai, Moshe Finel, Feng Zhang, Dongzhu Tu, Ling Yang and Guangbo Ge
      Drug Metabolism and Disposition October 2023, 51 (10) 1254-1272; DOI: https://doi.org/10.1124/dmd.122.001068

  5. Zhao, Yumeng

    1. Bioanalytical Assays for Pharmacokinetic and Biodistribution Study of Antibody-Drug Conjugates
      Lei Yin, Aiyun Xu, Yumeng Zhao and Jingkai Gu
      Drug Metabolism and Disposition October 2023, 51 (10) 1324-1331; DOI: https://doi.org/10.1124/dmd.123.001313

  6. Zheng, Jiang

    1. Recent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and Metabolomics
      Yu Chen, Ying Liu, Ximei Li, Yan He, Weiwei Li, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition October 2023, 51 (10) 1273-1283; DOI: https://doi.org/10.1124/dmd.122.001069

  7. Zheng, Qingchuan

    1. The Important Role of Transporter Structures in Drug Disposition, Efficacy, and Toxicity
      The Important Role of Transporter Structures in Drug Disposition, Efficacy, and Toxicity
      Tingting Fu, Su Zeng, Qingchuan Zheng and Feng Zhu
      Drug Metabolism and Disposition October 2023, 51 (10) 1316-1323; DOI: https://doi.org/10.1124/dmd.123.001275

  8. Zhong, Xiao-bo

    1. Special Section on New and Emerging Areas and Technologies in Drug Metabolism and Disposition, Part I–Editorial
      Xiao-bo Zhong, Yurong Lai and Xinxin Ding
      Drug Metabolism and Disposition October 2023, 51 (10) 1227-1229; DOI: https://doi.org/10.1124/dmd.123.001480

  9. Zhu, Feng

    1. The Important Role of Transporter Structures in Drug Disposition, Efficacy, and Toxicity
      The Important Role of Transporter Structures in Drug Disposition, Efficacy, and Toxicity
      Tingting Fu, Su Zeng, Qingchuan Zheng and Feng Zhu
      Drug Metabolism and Disposition October 2023, 51 (10) 1316-1323; DOI: https://doi.org/10.1124/dmd.123.001275

  10. Zientek, Michael A.

    1. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
      Sandhya Subash, Dilip K. Singh, Deepak S. Ahire, S. Cyrus Khojasteh, Bernard P. Murray, Michael A. Zientek, Robert S. Jones, Priyanka Kulkarni, Bill J. Smith, Scott Heyward, Ciarán N. Cronin and Bhagwat Prasad
      Drug Metabolism and Disposition October 2023, 51 (10) 1362-1371; DOI: https://doi.org/10.1124/dmd.123.001379
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