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Research ArticleArticle

Impact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4

Luc R.A. Rougée, David W. Bedwell, Kasi Hansen, Trent L. Abraham and Stephen D. Hall
Drug Metabolism and Disposition October 2023, 51 (10) 1372-1380; DOI: https://doi.org/10.1124/dmd.123.001382

Article Information

vol. 51 no. 10 1372-1380
DOI 
https://doi.org/10.1124/dmd.123.001382
PubMed 
37524542
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 2, 2023
  • Accepted July 20, 2023
  • Published online September 14, 2023.

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Copyright & Usage 
Copyright © 2023 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Luc R.A. Rougée,
  2. David W. Bedwell,
  3. Kasi Hansen,
  4. Trent L. Abraham, and
  5. Stephen D. Hall
  1. Lilly Research Laboratories; Eli Lilly and Company, Indianapolis, Indiana
  1. Address correspondence to:
    Luc Rougée, Eli Lilly Corporate Center, Indianapolis, IN 46285. E-mail: lrougee{at}lilly.com
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Research ArticleArticle

Allosteric Modulation of CYP3A4 Time-Dependent Inhibition

Luc R.A. Rougée, David W. Bedwell, Kasi Hansen, Trent L. Abraham and Stephen D. Hall
Drug Metabolism and Disposition October 1, 2023, 51 (10) 1372-1380; DOI: https://doi.org/10.1124/dmd.123.001382
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