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Prediction of Human Pharmacokinetics of Phosphorodiamidate Morpholino Oligonucleotides in Duchenne Muscular Dystrophy Patients Using Viltolarsen

Shunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi Kusano
Drug Metabolism and Disposition October 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425

Article Information

vol. 51 no. 10 1428-1435
DOI 
https://doi.org/10.1124/dmd.123.001425
PubMed 
37468285
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 16, 2023
  • Accepted July 14, 2023
  • Published online September 14, 2023.

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Copyright & Usage 
Copyright © 2023 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Shunji Imai,
  2. Yusuke Suda,
  3. Jumpei Mori,
  4. Yoshihiro Sasaki,
  5. Tetsuhiro Yamada, and
  6. Kazutomi Kusano
  1. Drug Metabolism and Pharmacokinetics Research Department, Discovery Research Laboratories, Nippon Shinyaku Co., Ltd., Kyoto, Japan
  1. Address correspondence to:
    Dr. Shunji Imai, 14, Nishinosho-monguchi-cho, Kisshoin, Minami-ku, Kyoto 601-8550, Japan. E-mail: sy.imai{at}po.nippon-shinyaku.co.jp
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Predicting the Human Pharmacokinetics of PMOs

Shunji Imai, Yusuke Suda, Jumpei Mori, Yoshihiro Sasaki, Tetsuhiro Yamada and Kazutomi Kusano
Drug Metabolism and Disposition October 1, 2023, 51 (10) 1428-1435; DOI: https://doi.org/10.1124/dmd.123.001425
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