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Cover Caption

About the Cover: Xenobiotic receptors are master regulators of drug metabolism and beyond. Image created and used with permission by Wen Xie.

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Drug Metabolism and Disposition: 51 (2)

Drug Metabolism and Disposition

Vol. 51, Issue 2

1 Feb 2023

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Special Section on Xenobiotic Receptors
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Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUC_I/AUC) RATIOS
In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”

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