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Index by author

February 01, 2023; Volume 51,Issue 2

A

  1. Abe, Satoshi

    1. Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse Cyp2c and Cyp3a Genes
      Kaoru Kobayashi, Genki Minegishi, Nina Kuriyama, Atsushi Miyajima, Satoshi Abe, Kanako Kazuki and Yasuhiro Kazuki
      Drug Metabolism and Disposition February 2023, 51 (2) 174-182; DOI: https://doi.org/10.1124/dmd.122.001087

  2. Ames, Matthew M.

    1. Bioavailability and Pharmacokinetics of Endoxifen in Female Rats and Dogs: Evidence to Support the Use of Endoxifen to Overcome the Limitations of CYP2D6-Mediated Tamoxifen Metabolism
      Emily J. Koubek, Sarah A. Buhrow, Stephanie L. Safgren, Lee Jia, Matthew P. Goetz, Matthew M. Ames and Joel M. Reid
      Drug Metabolism and Disposition February 2023, 51 (2) 183-192; DOI: https://doi.org/10.1124/dmd.122.000929

  3. Arya, Vikram

    1. Clinical Pharmacology of RNA Interference–Based Therapeutics: A Summary Based on Food and Drug Administration–Approved Small Interfering RNAs
      Xing Jing, Vikram Arya, Kellie Schoolar Reynolds and Hobart Rogers
      Drug Metabolism and Disposition February 2023, 51 (2) 193-198; DOI: https://doi.org/10.1124/dmd.122.001107

B

  1. Banuvar, Suzanne

    1. Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants
      Jialin Liu, Suzanne Banuvar, Marlos Viana, Elena Barengolts, Shao-Nong Chen, Guido F. Pauli and Richard B. van Breemen
      Drug Metabolism and Disposition February 2023, 51 (2) 199-204; DOI: https://doi.org/10.1124/dmd.122.001050

  2. Barengolts, Elena

    1. Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants
      Jialin Liu, Suzanne Banuvar, Marlos Viana, Elena Barengolts, Shao-Nong Chen, Guido F. Pauli and Richard B. van Breemen
      Drug Metabolism and Disposition February 2023, 51 (2) 199-204; DOI: https://doi.org/10.1124/dmd.122.001050

  3. Billheimer, Dean

    1. Renal Transporter Alterations in Patients with Chronic Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination
      Kayla L. Frost, Joseph L. Jilek, Shripad Sinari, Robert R. Klein, Dean Billheimer, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition February 2023, 51 (2) 155-164; DOI: https://doi.org/10.1124/dmd.122.001038

  4. Bischoff, Rainer

    1. Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Open Access
      Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Oladapo Olaleye, Baubek Spanov, Peter Bults, Anna van der Voort, Natalia Govorukhina, Gabe S. Sonke, Peter Horvatovich, Nico C. van de Merbel and Rainer Bischoff
      Drug Metabolism and Disposition February 2023, 51 (2) 249-256; DOI: https://doi.org/10.1124/dmd.122.001094

  5. Brundage, Richard C.

    1. A Physiological-Based Pharmacokinetic Model Embedded with a Target-Mediated Drug Disposition Mechanism Can Characterize Single-Dose Warfarin Pharmacokinetic Profiles in Subjects with Various CYP2C9 Genotypes under Different Cotreatments
      Shen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. Tracy
      Drug Metabolism and Disposition February 2023, 51 (2) 257-267; DOI: https://doi.org/10.1124/dmd.122.001048

  6. Buhrow, Sarah A.

    1. Bioavailability and Pharmacokinetics of Endoxifen in Female Rats and Dogs: Evidence to Support the Use of Endoxifen to Overcome the Limitations of CYP2D6-Mediated Tamoxifen Metabolism
      Emily J. Koubek, Sarah A. Buhrow, Stephanie L. Safgren, Lee Jia, Matthew P. Goetz, Matthew M. Ames and Joel M. Reid
      Drug Metabolism and Disposition February 2023, 51 (2) 183-192; DOI: https://doi.org/10.1124/dmd.122.000929

  7. Bults, Peter

    1. Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Open Access
      Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Oladapo Olaleye, Baubek Spanov, Peter Bults, Anna van der Voort, Natalia Govorukhina, Gabe S. Sonke, Peter Horvatovich, Nico C. van de Merbel and Rainer Bischoff
      Drug Metabolism and Disposition February 2023, 51 (2) 249-256; DOI: https://doi.org/10.1124/dmd.122.001094

C

  1. Chen, Shao-Nong

    1. Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants
      Jialin Liu, Suzanne Banuvar, Marlos Viana, Elena Barengolts, Shao-Nong Chen, Guido F. Pauli and Richard B. van Breemen
      Drug Metabolism and Disposition February 2023, 51 (2) 199-204; DOI: https://doi.org/10.1124/dmd.122.001050

  2. Chen, Taosheng

    1. Regulation of Nuclear Receptors PXR and CAR by Small Molecules and Signal Crosstalk: Roles in Drug Metabolism and Beyond
      Shyaron Poudel, Andrew D. Huber and Taosheng Chen
      Drug Metabolism and Disposition February 2023, 51 (2) 228-236; DOI: https://doi.org/10.1124/dmd.122.000858

  3. Cheng, Shen

    1. A Physiological-Based Pharmacokinetic Model Embedded with a Target-Mediated Drug Disposition Mechanism Can Characterize Single-Dose Warfarin Pharmacokinetic Profiles in Subjects with Various CYP2C9 Genotypes under Different Cotreatments
      Shen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. Tracy
      Drug Metabolism and Disposition February 2023, 51 (2) 257-267; DOI: https://doi.org/10.1124/dmd.122.001048

  4. Cherrington, Nathan J.

    1. Renal Transporter Alterations in Patients with Chronic Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination
      Kayla L. Frost, Joseph L. Jilek, Shripad Sinari, Robert R. Klein, Dean Billheimer, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition February 2023, 51 (2) 155-164; DOI: https://doi.org/10.1124/dmd.122.001038

D

  1. Dvořák, Zdeněk

    1. Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future
      Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future
      Zdeněk Dvořák, Hao Li and Sridhar Mani
      Drug Metabolism and Disposition February 2023, 51 (2) 219-227; DOI: https://doi.org/10.1124/dmd.122.000860

F

  1. Flora, Darcy R.

    1. A Physiological-Based Pharmacokinetic Model Embedded with a Target-Mediated Drug Disposition Mechanism Can Characterize Single-Dose Warfarin Pharmacokinetic Profiles in Subjects with Various CYP2C9 Genotypes under Different Cotreatments
      Shen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. Tracy
      Drug Metabolism and Disposition February 2023, 51 (2) 257-267; DOI: https://doi.org/10.1124/dmd.122.001048

  2. Frost, Kayla L.

    1. Renal Transporter Alterations in Patients with Chronic Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination
      Kayla L. Frost, Joseph L. Jilek, Shripad Sinari, Robert R. Klein, Dean Billheimer, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition February 2023, 51 (2) 155-164; DOI: https://doi.org/10.1124/dmd.122.001038

G

  1. Goetz, Matthew P.

    1. Bioavailability and Pharmacokinetics of Endoxifen in Female Rats and Dogs: Evidence to Support the Use of Endoxifen to Overcome the Limitations of CYP2D6-Mediated Tamoxifen Metabolism
      Emily J. Koubek, Sarah A. Buhrow, Stephanie L. Safgren, Lee Jia, Matthew P. Goetz, Matthew M. Ames and Joel M. Reid
      Drug Metabolism and Disposition February 2023, 51 (2) 183-192; DOI: https://doi.org/10.1124/dmd.122.000929

  2. Govorukhina, Natalia

    1. Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Open Access
      Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Oladapo Olaleye, Baubek Spanov, Peter Bults, Anna van der Voort, Natalia Govorukhina, Gabe S. Sonke, Peter Horvatovich, Nico C. van de Merbel and Rainer Bischoff
      Drug Metabolism and Disposition February 2023, 51 (2) 249-256; DOI: https://doi.org/10.1124/dmd.122.001094

H

  1. He, Jinhan

    1. The Function of Xenobiotic Receptors in Metabolic Diseases
      Jinhang Zhang, Qingyi Jia, Yanping Li and Jinhan He
      Drug Metabolism and Disposition February 2023, 51 (2) 237-248; DOI: https://doi.org/10.1124/dmd.122.000862

  2. Hirasawa, Noriyasu

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  3. Hiratsuka, Masahiro

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  4. Hishinuma, Eiji

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  5. Horvatovich, Peter

    1. Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Open Access
      Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Oladapo Olaleye, Baubek Spanov, Peter Bults, Anna van der Voort, Natalia Govorukhina, Gabe S. Sonke, Peter Horvatovich, Nico C. van de Merbel and Rainer Bischoff
      Drug Metabolism and Disposition February 2023, 51 (2) 249-256; DOI: https://doi.org/10.1124/dmd.122.001094

  6. Huber, Andrew D.

    1. Regulation of Nuclear Receptors PXR and CAR by Small Molecules and Signal Crosstalk: Roles in Drug Metabolism and Beyond
      Shyaron Poudel, Andrew D. Huber and Taosheng Chen
      Drug Metabolism and Disposition February 2023, 51 (2) 228-236; DOI: https://doi.org/10.1124/dmd.122.000858

J

  1. Jia, Lee

    1. Bioavailability and Pharmacokinetics of Endoxifen in Female Rats and Dogs: Evidence to Support the Use of Endoxifen to Overcome the Limitations of CYP2D6-Mediated Tamoxifen Metabolism
      Emily J. Koubek, Sarah A. Buhrow, Stephanie L. Safgren, Lee Jia, Matthew P. Goetz, Matthew M. Ames and Joel M. Reid
      Drug Metabolism and Disposition February 2023, 51 (2) 183-192; DOI: https://doi.org/10.1124/dmd.122.000929

  2. Jia, Qingyi

    1. The Function of Xenobiotic Receptors in Metabolic Diseases
      Jinhang Zhang, Qingyi Jia, Yanping Li and Jinhan He
      Drug Metabolism and Disposition February 2023, 51 (2) 237-248; DOI: https://doi.org/10.1124/dmd.122.000862

  3. Jilek, Joseph L.

    1. Renal Transporter Alterations in Patients with Chronic Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination
      Kayla L. Frost, Joseph L. Jilek, Shripad Sinari, Robert R. Klein, Dean Billheimer, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition February 2023, 51 (2) 155-164; DOI: https://doi.org/10.1124/dmd.122.001038

  4. Jing, Xing

    1. Clinical Pharmacology of RNA Interference–Based Therapeutics: A Summary Based on Food and Drug Administration–Approved Small Interfering RNAs
      Xing Jing, Vikram Arya, Kellie Schoolar Reynolds and Hobart Rogers
      Drug Metabolism and Disposition February 2023, 51 (2) 193-198; DOI: https://doi.org/10.1124/dmd.122.001107

K

  1. Kazuki, Kanako

    1. Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse Cyp2c and Cyp3a Genes
      Kaoru Kobayashi, Genki Minegishi, Nina Kuriyama, Atsushi Miyajima, Satoshi Abe, Kanako Kazuki and Yasuhiro Kazuki
      Drug Metabolism and Disposition February 2023, 51 (2) 174-182; DOI: https://doi.org/10.1124/dmd.122.001087

  2. Kazuki, Yasuhiro

    1. Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse Cyp2c and Cyp3a Genes
      Kaoru Kobayashi, Genki Minegishi, Nina Kuriyama, Atsushi Miyajima, Satoshi Abe, Kanako Kazuki and Yasuhiro Kazuki
      Drug Metabolism and Disposition February 2023, 51 (2) 174-182; DOI: https://doi.org/10.1124/dmd.122.001087

  3. Kinoshita, Kengo

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  4. Klein, Robert R.

    1. Renal Transporter Alterations in Patients with Chronic Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination
      Kayla L. Frost, Joseph L. Jilek, Shripad Sinari, Robert R. Klein, Dean Billheimer, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition February 2023, 51 (2) 155-164; DOI: https://doi.org/10.1124/dmd.122.001038

  5. Kobayashi, Kaoru

    1. Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse Cyp2c and Cyp3a Genes
      Kaoru Kobayashi, Genki Minegishi, Nina Kuriyama, Atsushi Miyajima, Satoshi Abe, Kanako Kazuki and Yasuhiro Kazuki
      Drug Metabolism and Disposition February 2023, 51 (2) 174-182; DOI: https://doi.org/10.1124/dmd.122.001087

  6. Koubek, Emily J.

    1. Bioavailability and Pharmacokinetics of Endoxifen in Female Rats and Dogs: Evidence to Support the Use of Endoxifen to Overcome the Limitations of CYP2D6-Mediated Tamoxifen Metabolism
      Emily J. Koubek, Sarah A. Buhrow, Stephanie L. Safgren, Lee Jia, Matthew P. Goetz, Matthew M. Ames and Joel M. Reid
      Drug Metabolism and Disposition February 2023, 51 (2) 183-192; DOI: https://doi.org/10.1124/dmd.122.000929

  7. Kuriyama, Nina

    1. Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse Cyp2c and Cyp3a Genes
      Kaoru Kobayashi, Genki Minegishi, Nina Kuriyama, Atsushi Miyajima, Satoshi Abe, Kanako Kazuki and Yasuhiro Kazuki
      Drug Metabolism and Disposition February 2023, 51 (2) 174-182; DOI: https://doi.org/10.1124/dmd.122.001087

L

  1. Lai, Yurong

    1. Special Section on Xenobiotic Receptors–Editorial
      Xiao-bo Zhong and Yurong Lai
      Drug Metabolism and Disposition February 2023, 51 (2) 205-206; DOI: https://doi.org/10.1124/dmd.122.001207

  2. Li, Hao

    1. Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future
      Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future
      Zdeněk Dvořák, Hao Li and Sridhar Mani
      Drug Metabolism and Disposition February 2023, 51 (2) 219-227; DOI: https://doi.org/10.1124/dmd.122.000860

  3. Li, Yanping

    1. The Function of Xenobiotic Receptors in Metabolic Diseases
      Jinhang Zhang, Qingyi Jia, Yanping Li and Jinhan He
      Drug Metabolism and Disposition February 2023, 51 (2) 237-248; DOI: https://doi.org/10.1124/dmd.122.000862

  4. Liu, Jialin

    1. Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants
      Jialin Liu, Suzanne Banuvar, Marlos Viana, Elena Barengolts, Shao-Nong Chen, Guido F. Pauli and Richard B. van Breemen
      Drug Metabolism and Disposition February 2023, 51 (2) 199-204; DOI: https://doi.org/10.1124/dmd.122.001050

M

  1. Maekawa, Masamitsu

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  2. Mani, Sridhar

    1. Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future
      Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future
      Zdeněk Dvořák, Hao Li and Sridhar Mani
      Drug Metabolism and Disposition February 2023, 51 (2) 219-227; DOI: https://doi.org/10.1124/dmd.122.000860

  3. Mano, Nariyasu

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  4. Men, Shuaiqian

    1. Phenobarbital in Nuclear Receptor Activation: An Update
      Shuaiqian Men and Hongbing Wang
      Drug Metabolism and Disposition February 2023, 51 (2) 210-218; DOI: https://doi.org/10.1124/dmd.122.000859

  5. Minegishi, Genki

    1. Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse Cyp2c and Cyp3a Genes
      Kaoru Kobayashi, Genki Minegishi, Nina Kuriyama, Atsushi Miyajima, Satoshi Abe, Kanako Kazuki and Yasuhiro Kazuki
      Drug Metabolism and Disposition February 2023, 51 (2) 174-182; DOI: https://doi.org/10.1124/dmd.122.001087

  6. Miyajima, Atsushi

    1. Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse Cyp2c and Cyp3a Genes
      Kaoru Kobayashi, Genki Minegishi, Nina Kuriyama, Atsushi Miyajima, Satoshi Abe, Kanako Kazuki and Yasuhiro Kazuki
      Drug Metabolism and Disposition February 2023, 51 (2) 174-182; DOI: https://doi.org/10.1124/dmd.122.001087

N

  1. Nakayoshi, Tomoki

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  2. Narita, Yoko

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

O

  1. Obuchi, Kai

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  2. Oda, Akifumi

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  3. Olaleye, Oladapo

    1. Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Open Access
      Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Oladapo Olaleye, Baubek Spanov, Peter Bults, Anna van der Voort, Natalia Govorukhina, Gabe S. Sonke, Peter Horvatovich, Nico C. van de Merbel and Rainer Bischoff
      Drug Metabolism and Disposition February 2023, 51 (2) 249-256; DOI: https://doi.org/10.1124/dmd.122.001094

P

  1. Pauli, Guido F.

    1. Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants
      Jialin Liu, Suzanne Banuvar, Marlos Viana, Elena Barengolts, Shao-Nong Chen, Guido F. Pauli and Richard B. van Breemen
      Drug Metabolism and Disposition February 2023, 51 (2) 199-204; DOI: https://doi.org/10.1124/dmd.122.001050

  2. Poudel, Shyaron

    1. Regulation of Nuclear Receptors PXR and CAR by Small Molecules and Signal Crosstalk: Roles in Drug Metabolism and Beyond
      Shyaron Poudel, Andrew D. Huber and Taosheng Chen
      Drug Metabolism and Disposition February 2023, 51 (2) 228-236; DOI: https://doi.org/10.1124/dmd.122.000858

R

  1. Reid, Joel M.

    1. Bioavailability and Pharmacokinetics of Endoxifen in Female Rats and Dogs: Evidence to Support the Use of Endoxifen to Overcome the Limitations of CYP2D6-Mediated Tamoxifen Metabolism
      Emily J. Koubek, Sarah A. Buhrow, Stephanie L. Safgren, Lee Jia, Matthew P. Goetz, Matthew M. Ames and Joel M. Reid
      Drug Metabolism and Disposition February 2023, 51 (2) 183-192; DOI: https://doi.org/10.1124/dmd.122.000929

  2. Rettie, Allan E.

    1. A Physiological-Based Pharmacokinetic Model Embedded with a Target-Mediated Drug Disposition Mechanism Can Characterize Single-Dose Warfarin Pharmacokinetic Profiles in Subjects with Various CYP2C9 Genotypes under Different Cotreatments
      Shen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. Tracy
      Drug Metabolism and Disposition February 2023, 51 (2) 257-267; DOI: https://doi.org/10.1124/dmd.122.001048

  3. Reynolds, Kellie Schoolar

    1. Clinical Pharmacology of RNA Interference–Based Therapeutics: A Summary Based on Food and Drug Administration–Approved Small Interfering RNAs
      Xing Jing, Vikram Arya, Kellie Schoolar Reynolds and Hobart Rogers
      Drug Metabolism and Disposition February 2023, 51 (2) 193-198; DOI: https://doi.org/10.1124/dmd.122.001107

  4. Rico, Evelyn Marie Gutiérrez

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  5. Rogers, Hobart

    1. Clinical Pharmacology of RNA Interference–Based Therapeutics: A Summary Based on Food and Drug Administration–Approved Small Interfering RNAs
      Xing Jing, Vikram Arya, Kellie Schoolar Reynolds and Hobart Rogers
      Drug Metabolism and Disposition February 2023, 51 (2) 193-198; DOI: https://doi.org/10.1124/dmd.122.001107

S

  1. Safgren, Stephanie L.

    1. Bioavailability and Pharmacokinetics of Endoxifen in Female Rats and Dogs: Evidence to Support the Use of Endoxifen to Overcome the Limitations of CYP2D6-Mediated Tamoxifen Metabolism
      Emily J. Koubek, Sarah A. Buhrow, Stephanie L. Safgren, Lee Jia, Matthew P. Goetz, Matthew M. Ames and Joel M. Reid
      Drug Metabolism and Disposition February 2023, 51 (2) 183-192; DOI: https://doi.org/10.1124/dmd.122.000929

  2. Saito, Sakae

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  3. Sinari, Shripad

    1. Renal Transporter Alterations in Patients with Chronic Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination
      Kayla L. Frost, Joseph L. Jilek, Shripad Sinari, Robert R. Klein, Dean Billheimer, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition February 2023, 51 (2) 155-164; DOI: https://doi.org/10.1124/dmd.122.001038

  4. Sonke, Gabe S.

    1. Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Open Access
      Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Oladapo Olaleye, Baubek Spanov, Peter Bults, Anna van der Voort, Natalia Govorukhina, Gabe S. Sonke, Peter Horvatovich, Nico C. van de Merbel and Rainer Bischoff
      Drug Metabolism and Disposition February 2023, 51 (2) 249-256; DOI: https://doi.org/10.1124/dmd.122.001094

  5. Spanov, Baubek

    1. Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Open Access
      Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Oladapo Olaleye, Baubek Spanov, Peter Bults, Anna van der Voort, Natalia Govorukhina, Gabe S. Sonke, Peter Horvatovich, Nico C. van de Merbel and Rainer Bischoff
      Drug Metabolism and Disposition February 2023, 51 (2) 249-256; DOI: https://doi.org/10.1124/dmd.122.001094

T

  1. Tadaka, Shu

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  2. Tanaka, Yoshikazu

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

  3. Tracy, Timothy S.

    1. A Physiological-Based Pharmacokinetic Model Embedded with a Target-Mediated Drug Disposition Mechanism Can Characterize Single-Dose Warfarin Pharmacokinetic Profiles in Subjects with Various CYP2C9 Genotypes under Different Cotreatments
      Shen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. Tracy
      Drug Metabolism and Disposition February 2023, 51 (2) 257-267; DOI: https://doi.org/10.1124/dmd.122.001048

U

  1. Ueda, Akiko

    1. Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
      Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition February 2023, 51 (2) 165-173; DOI: https://doi.org/10.1124/dmd.122.001045

V

  1. van Breemen, Richard B.

    1. Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants
      Jialin Liu, Suzanne Banuvar, Marlos Viana, Elena Barengolts, Shao-Nong Chen, Guido F. Pauli and Richard B. van Breemen
      Drug Metabolism and Disposition February 2023, 51 (2) 199-204; DOI: https://doi.org/10.1124/dmd.122.001050

  2. van de Merbel, Nico C.

    1. Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Open Access
      Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Oladapo Olaleye, Baubek Spanov, Peter Bults, Anna van der Voort, Natalia Govorukhina, Gabe S. Sonke, Peter Horvatovich, Nico C. van de Merbel and Rainer Bischoff
      Drug Metabolism and Disposition February 2023, 51 (2) 249-256; DOI: https://doi.org/10.1124/dmd.122.001094

  3. van der Voort, Anna

    1. Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Open Access
      Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography
      Oladapo Olaleye, Baubek Spanov, Peter Bults, Anna van der Voort, Natalia Govorukhina, Gabe S. Sonke, Peter Horvatovich, Nico C. van de Merbel and Rainer Bischoff
      Drug Metabolism and Disposition February 2023, 51 (2) 249-256; DOI: https://doi.org/10.1124/dmd.122.001094

  4. Viana, Marlos

    1. Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants
      Jialin Liu, Suzanne Banuvar, Marlos Viana, Elena Barengolts, Shao-Nong Chen, Guido F. Pauli and Richard B. van Breemen
      Drug Metabolism and Disposition February 2023, 51 (2) 199-204; DOI: https://doi.org/10.1124/dmd.122.001050

W

  1. Wang, Hongbing

    1. Phenobarbital in Nuclear Receptor Activation: An Update
      Shuaiqian Men and Hongbing Wang
      Drug Metabolism and Disposition February 2023, 51 (2) 210-218; DOI: https://doi.org/10.1124/dmd.122.000859

  2. Wright, Stephen H.

    1. Renal Transporter Alterations in Patients with Chronic Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination
      Kayla L. Frost, Joseph L. Jilek, Shripad Sinari, Robert R. Klein, Dean Billheimer, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition February 2023, 51 (2) 155-164; DOI: https://doi.org/10.1124/dmd.122.001038

X

  1. Xie, Wen

    1. Xenobiotic Receptors, a Journey of Rewards
      Wen Xie
      Drug Metabolism and Disposition February 2023, 51 (2) 207-209; DOI: https://doi.org/10.1124/dmd.122.000857

Z

  1. Zhang, Jinhang

    1. The Function of Xenobiotic Receptors in Metabolic Diseases
      Jinhang Zhang, Qingyi Jia, Yanping Li and Jinhan He
      Drug Metabolism and Disposition February 2023, 51 (2) 237-248; DOI: https://doi.org/10.1124/dmd.122.000862

  2. Zhong, Xiao-bo

    1. Special Section on Xenobiotic Receptors–Editorial
      Xiao-bo Zhong and Yurong Lai
      Drug Metabolism and Disposition February 2023, 51 (2) 205-206; DOI: https://doi.org/10.1124/dmd.122.001207
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