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Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography

Oladapo Olaleye, Baubek Spanov, Peter Bults, Anna van der Voort, Natalia Govorukhina, Gabe S. Sonke, Peter Horvatovich, Nico C. van de Merbel and Rainer Bischoff
Drug Metabolism and Disposition February 2023, 51 (2) 249-256; DOI: https://doi.org/10.1124/dmd.122.001094

Article Information

vol. 51 no. 2 249-256
DOI 
https://doi.org/10.1124/dmd.122.001094
PubMed 
36379709
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 31, 2022
  • Accepted October 21, 2022
  • Published online January 26, 2023.

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Copyright & Usage 
Copyright © 2023 The Author(s) This is an open access article distributed under the CC BY Attribution 4.0 International license.

Author Information

  1. Oladapo Olaleye1,
  2. Baubek Spanov1,
  3. Peter Bults2,
  4. Anna van der Voort3,
  5. Natalia Govorukhina1,
  6. Gabe S. Sonke3,
  7. Peter Horvatovich1,
  8. Nico C. van de Merbel1,2, and
  9. Rainer Bischoff1
  1. Department of Analytical Biochemistry, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands
  1. Address correspondence to:
    Rainer Bischoff, Department of Analytical Biochemistry, Groningen Research Institute of Pharmacy, University of Groningen, A Deusinglaan 1, 9713 AV Groningen, The Netherlands. E-mail: r.p.h.bischoff{at}rug.nl
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Research ArticleArticle

Biotransformation of Trastuzumab and Pertuzumab

Oladapo Olaleye, Baubek Spanov, Peter Bults, Anna van der Voort, Natalia Govorukhina, Gabe S. Sonke, Peter Horvatovich, Nico C. van de Merbel and Rainer Bischoff
Drug Metabolism and Disposition February 1, 2023, 51 (2) 249-256; DOI: https://doi.org/10.1124/dmd.122.001094
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