Advertisement

Index by author

March 01, 2023; Volume 51,Issue 3

A

  1. Ahire, Deepak

    1. Quantification of Accurate Composition and Total Abundance of Homologous Proteins by Conserved-Plus-Surrogate Peptide Approach: Quantification of UDP Glucuronosyltransferases in Human Tissues
      Deepak Ahire, Mitesh Patel, Sujal V. Deshmukh and Bhagwat Prasad
      Drug Metabolism and Disposition March 2023, 51 (3) 285-292; DOI: https://doi.org/10.1124/dmd.122.001155

  2. Angle, Ethan D.

    1. Multidisciplinary Insights into the Structure–Function Relationship of the CYP2B6 Active Site
      Ethan D. Angle and Philip M. Cox
      Drug Metabolism and Disposition March 2023, 51 (3) 369-384; DOI: https://doi.org/10.1124/dmd.122.000853

  3. Asano, Satoshi

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

B

  1. Backman, Janne T.

    1. Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A <em>in vitro</em>
      Open Access
      Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro
      Marie-Noëlle Paludetto, Mika Kurkela, Helinä Kahma, Janne T. Backman, Mikko Niemi and Anne M. Filppula
      Drug Metabolism and Disposition March 2023, 51 (3) 293-305; DOI: https://doi.org/10.1124/dmd.122.001018

  2. Bo, Yan

    1. Quantitative Cytochrome P450 3A4 Induction Risk Assessment Using Human Hepatocytes Complemented with Pregnane X Receptor-Activating Profiles
      Aynur Ekiciler, Wen Li Kelly Chen, Yan Bo, Alessandra Pugliano, Massimiliano Donzelli, Neil Parrott and Kenichi Umehara
      Drug Metabolism and Disposition March 2023, 51 (3) 276-284; DOI: https://doi.org/10.1124/dmd.122.001132

  3. Brown, Robin M.

    1. Open Access
      Intravital Microscopy Reveals Unforeseen Biodistribution Within the Liver and Kidney Mechanistically Connected to the Clearance of a Bifunctional Antibody
      Amita Datta-Mannan, Bruce A. Molitoris, Yiqing Feng, Michelle M. Martinez, Ruben M. Sandoval, Robin M. Brown, Daniel Merkel, Johnny E. Croy and Kenneth W. Dunn
      Drug Metabolism and Disposition March 2023, 51 (3) 403-412; DOI: https://doi.org/10.1124/dmd.122.001049

  4. Bumpus, Namandjé N.

    1. Open Access
      Achieving a Deeper Understanding of Drug Metabolism and Responses Using Single-Cell Technologies
      Abigail M. Wheeler, Colten D. Eberhard, Eric P. Mosher, Yuting Yuan, Hannah N. Wilkins, Herana Kamal Seneviratne, Benjamin C. Orsburn and Namandjé N. Bumpus
      Drug Metabolism and Disposition March 2023, 51 (3) 350-359; DOI: https://doi.org/10.1124/dmd.122.001043

C

  1. Chen, Wen Li Kelly

    1. Quantitative Cytochrome P450 3A4 Induction Risk Assessment Using Human Hepatocytes Complemented with Pregnane X Receptor-Activating Profiles
      Aynur Ekiciler, Wen Li Kelly Chen, Yan Bo, Alessandra Pugliano, Massimiliano Donzelli, Neil Parrott and Kenichi Umehara
      Drug Metabolism and Disposition March 2023, 51 (3) 276-284; DOI: https://doi.org/10.1124/dmd.122.001132

  2. Chen, Xin

    1. Maternal and Fetal Exposure to (-)-Δ9-tetrahydrocannabinol and Its Major Metabolites in Pregnant Mice Is Differentially Impacted by P-glycoprotein and Breast Cancer Resistance Protein
      Xin Chen, Jashvant D. Unadkat and Qingcheng Mao
      Drug Metabolism and Disposition March 2023, 51 (3) 269-275; DOI: https://doi.org/10.1124/dmd.122.001110

  3. Cox, Philip M.

    1. Multidisciplinary Insights into the Structure–Function Relationship of the CYP2B6 Active Site
      Ethan D. Angle and Philip M. Cox
      Drug Metabolism and Disposition March 2023, 51 (3) 369-384; DOI: https://doi.org/10.1124/dmd.122.000853

  4. Croy, Johnny E.

    1. Open Access
      Intravital Microscopy Reveals Unforeseen Biodistribution Within the Liver and Kidney Mechanistically Connected to the Clearance of a Bifunctional Antibody
      Amita Datta-Mannan, Bruce A. Molitoris, Yiqing Feng, Michelle M. Martinez, Ruben M. Sandoval, Robin M. Brown, Daniel Merkel, Johnny E. Croy and Kenneth W. Dunn
      Drug Metabolism and Disposition March 2023, 51 (3) 403-412; DOI: https://doi.org/10.1124/dmd.122.001049

D

  1. Datta-Mannan, Amita

    1. Open Access
      Intravital Microscopy Reveals Unforeseen Biodistribution Within the Liver and Kidney Mechanistically Connected to the Clearance of a Bifunctional Antibody
      Amita Datta-Mannan, Bruce A. Molitoris, Yiqing Feng, Michelle M. Martinez, Ruben M. Sandoval, Robin M. Brown, Daniel Merkel, Johnny E. Croy and Kenneth W. Dunn
      Drug Metabolism and Disposition March 2023, 51 (3) 403-412; DOI: https://doi.org/10.1124/dmd.122.001049

  2. Deshmukh, Sujal V.

    1. Quantification of Accurate Composition and Total Abundance of Homologous Proteins by Conserved-Plus-Surrogate Peptide Approach: Quantification of UDP Glucuronosyltransferases in Human Tissues
      Deepak Ahire, Mitesh Patel, Sujal V. Deshmukh and Bhagwat Prasad
      Drug Metabolism and Disposition March 2023, 51 (3) 285-292; DOI: https://doi.org/10.1124/dmd.122.001155

  3. Donzelli, Massimiliano

    1. Quantitative Cytochrome P450 3A4 Induction Risk Assessment Using Human Hepatocytes Complemented with Pregnane X Receptor-Activating Profiles
      Aynur Ekiciler, Wen Li Kelly Chen, Yan Bo, Alessandra Pugliano, Massimiliano Donzelli, Neil Parrott and Kenichi Umehara
      Drug Metabolism and Disposition March 2023, 51 (3) 276-284; DOI: https://doi.org/10.1124/dmd.122.001132

  4. Dunn, Kenneth W.

    1. Open Access
      Intravital Microscopy Reveals Unforeseen Biodistribution Within the Liver and Kidney Mechanistically Connected to the Clearance of a Bifunctional Antibody
      Amita Datta-Mannan, Bruce A. Molitoris, Yiqing Feng, Michelle M. Martinez, Ruben M. Sandoval, Robin M. Brown, Daniel Merkel, Johnny E. Croy and Kenneth W. Dunn
      Drug Metabolism and Disposition March 2023, 51 (3) 403-412; DOI: https://doi.org/10.1124/dmd.122.001049

E

  1. Eberhard, Colten D.

    1. Open Access
      Achieving a Deeper Understanding of Drug Metabolism and Responses Using Single-Cell Technologies
      Abigail M. Wheeler, Colten D. Eberhard, Eric P. Mosher, Yuting Yuan, Hannah N. Wilkins, Herana Kamal Seneviratne, Benjamin C. Orsburn and Namandjé N. Bumpus
      Drug Metabolism and Disposition March 2023, 51 (3) 350-359; DOI: https://doi.org/10.1124/dmd.122.001043

  2. Ekiciler, Aynur

    1. Quantitative Cytochrome P450 3A4 Induction Risk Assessment Using Human Hepatocytes Complemented with Pregnane X Receptor-Activating Profiles
      Aynur Ekiciler, Wen Li Kelly Chen, Yan Bo, Alessandra Pugliano, Massimiliano Donzelli, Neil Parrott and Kenichi Umehara
      Drug Metabolism and Disposition March 2023, 51 (3) 276-284; DOI: https://doi.org/10.1124/dmd.122.001132

  3. Enokizono, Junichi

    1. Comprehensive Analyses of the Intracellular and in Vivo Disposition of Fab– Small Interfering RNA Conjugate to Identify Key Issues to Improve Its in Vivo Activity
      Comprehensive Analyses of the Intracellular and in Vivo Disposition of Fab– Small Interfering RNA Conjugate to Identify Key Issues to Improve Its in Vivo Activity
      Asami Toshima, Yasuhisa Shiraishi, Daisuke Shinmi, Yoshiyuki Kagawa and Junichi Enokizono
      Drug Metabolism and Disposition March 2023, 51 (3) 338-347; DOI: https://doi.org/10.1124/dmd.122.001098

F

  1. Feng, Yiqing

    1. Open Access
      Intravital Microscopy Reveals Unforeseen Biodistribution Within the Liver and Kidney Mechanistically Connected to the Clearance of a Bifunctional Antibody
      Amita Datta-Mannan, Bruce A. Molitoris, Yiqing Feng, Michelle M. Martinez, Ruben M. Sandoval, Robin M. Brown, Daniel Merkel, Johnny E. Croy and Kenneth W. Dunn
      Drug Metabolism and Disposition March 2023, 51 (3) 403-412; DOI: https://doi.org/10.1124/dmd.122.001049

  2. Filppula, Anne M.

    1. Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A <em>in vitro</em>
      Open Access
      Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro
      Marie-Noëlle Paludetto, Mika Kurkela, Helinä Kahma, Janne T. Backman, Mikko Niemi and Anne M. Filppula
      Drug Metabolism and Disposition March 2023, 51 (3) 293-305; DOI: https://doi.org/10.1124/dmd.122.001018

  3. Fowler, Stephen

    1. Contribution of UGT Enzymes to Human Drug Metabolism Stereoselectivity: A Case Study of Medetomidine, RO5263397, Propranolol, and Testosterone
      Nicolò Milani, NaHong Qiu and Stephen Fowler
      Drug Metabolism and Disposition March 2023, 51 (3) 306-317; DOI: https://doi.org/10.1124/dmd.122.001024

G

  1. Gillam, Elizabeth M.J.

    1. Opportunities for Accelerating Drug Discovery and Development by Using Engineered Drug-Metabolizing Enzymes
      Elizabeth M.J. Gillam and Valerie M. Kramlinger
      Drug Metabolism and Disposition March 2023, 51 (3) 392-402; DOI: https://doi.org/10.1124/dmd.121.000743

H

  1. Hashimoto, Natsumi

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

  2. Hisaka, Akihiro

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

  3. Hozuki, Shizuka

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

I

  1. Iijima, Takeshi

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

K

  1. Kagawa, Yoshiyuki

    1. Comprehensive Analyses of the Intracellular and in Vivo Disposition of Fab– Small Interfering RNA Conjugate to Identify Key Issues to Improve Its in Vivo Activity
      Comprehensive Analyses of the Intracellular and in Vivo Disposition of Fab– Small Interfering RNA Conjugate to Identify Key Issues to Improve Its in Vivo Activity
      Asami Toshima, Yasuhisa Shiraishi, Daisuke Shinmi, Yoshiyuki Kagawa and Junichi Enokizono
      Drug Metabolism and Disposition March 2023, 51 (3) 338-347; DOI: https://doi.org/10.1124/dmd.122.001098

  2. Kageyama, Michiharu

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

  3. Kahma, Helinä

    1. Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A <em>in vitro</em>
      Open Access
      Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro
      Marie-Noëlle Paludetto, Mika Kurkela, Helinä Kahma, Janne T. Backman, Mikko Niemi and Anne M. Filppula
      Drug Metabolism and Disposition March 2023, 51 (3) 293-305; DOI: https://doi.org/10.1124/dmd.122.001018

  4. Kazuki, Yasuhiro

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

  5. Kimura, Shunsuke

    1. Pharmacokinetic/Pharmacodynamic Models of an Alzheimer’s Drug, Donepezil, in Rats
      Pharmacokinetic/Pharmacodynamic Models of an Alzheimer’s Drug, Donepezil, in Rats
      Akiko Kiriyama, Shunsuke Kimura and Shugo Yamashita
      Drug Metabolism and Disposition March 2023, 51 (3) 329-337; DOI: https://doi.org/10.1124/dmd.122.001061

  6. Kiriyama, Akiko

    1. Pharmacokinetic/Pharmacodynamic Models of an Alzheimer’s Drug, Donepezil, in Rats
      Pharmacokinetic/Pharmacodynamic Models of an Alzheimer’s Drug, Donepezil, in Rats
      Akiko Kiriyama, Shunsuke Kimura and Shugo Yamashita
      Drug Metabolism and Disposition March 2023, 51 (3) 329-337; DOI: https://doi.org/10.1124/dmd.122.001061

  7. Kramlinger, Valerie M.

    1. Opportunities for Accelerating Drug Discovery and Development by Using Engineered Drug-Metabolizing Enzymes
      Elizabeth M.J. Gillam and Valerie M. Kramlinger
      Drug Metabolism and Disposition March 2023, 51 (3) 392-402; DOI: https://doi.org/10.1124/dmd.121.000743

  8. Kurkela, Mika

    1. Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A <em>in vitro</em>
      Open Access
      Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro
      Marie-Noëlle Paludetto, Mika Kurkela, Helinä Kahma, Janne T. Backman, Mikko Niemi and Anne M. Filppula
      Drug Metabolism and Disposition March 2023, 51 (3) 293-305; DOI: https://doi.org/10.1124/dmd.122.001018

L

  1. Lai, Yurong

    1. Special Section on Drug Metabolism and Precision Medicine—Editorial
      Xiao-bo Zhong and Yurong Lai
      Drug Metabolism and Disposition March 2023, 51 (3) 348-349; DOI: https://doi.org/10.1124/dmd.122.001243

M

  1. Mao, Qingcheng

    1. Maternal and Fetal Exposure to (-)-Δ9-tetrahydrocannabinol and Its Major Metabolites in Pregnant Mice Is Differentially Impacted by P-glycoprotein and Breast Cancer Resistance Protein
      Xin Chen, Jashvant D. Unadkat and Qingcheng Mao
      Drug Metabolism and Disposition March 2023, 51 (3) 269-275; DOI: https://doi.org/10.1124/dmd.122.001110

  2. Martinez, Michelle M.

    1. Open Access
      Intravital Microscopy Reveals Unforeseen Biodistribution Within the Liver and Kidney Mechanistically Connected to the Clearance of a Bifunctional Antibody
      Amita Datta-Mannan, Bruce A. Molitoris, Yiqing Feng, Michelle M. Martinez, Ruben M. Sandoval, Robin M. Brown, Daniel Merkel, Johnny E. Croy and Kenneth W. Dunn
      Drug Metabolism and Disposition March 2023, 51 (3) 403-412; DOI: https://doi.org/10.1124/dmd.122.001049

  3. Merkel, Daniel

    1. Open Access
      Intravital Microscopy Reveals Unforeseen Biodistribution Within the Liver and Kidney Mechanistically Connected to the Clearance of a Bifunctional Antibody
      Amita Datta-Mannan, Bruce A. Molitoris, Yiqing Feng, Michelle M. Martinez, Ruben M. Sandoval, Robin M. Brown, Daniel Merkel, Johnny E. Croy and Kenneth W. Dunn
      Drug Metabolism and Disposition March 2023, 51 (3) 403-412; DOI: https://doi.org/10.1124/dmd.122.001049

  4. Milani, Nicolò

    1. Contribution of UGT Enzymes to Human Drug Metabolism Stereoselectivity: A Case Study of Medetomidine, RO5263397, Propranolol, and Testosterone
      Nicolò Milani, NaHong Qiu and Stephen Fowler
      Drug Metabolism and Disposition March 2023, 51 (3) 306-317; DOI: https://doi.org/10.1124/dmd.122.001024

  5. Molitoris, Bruce A.

    1. Open Access
      Intravital Microscopy Reveals Unforeseen Biodistribution Within the Liver and Kidney Mechanistically Connected to the Clearance of a Bifunctional Antibody
      Amita Datta-Mannan, Bruce A. Molitoris, Yiqing Feng, Michelle M. Martinez, Ruben M. Sandoval, Robin M. Brown, Daniel Merkel, Johnny E. Croy and Kenneth W. Dunn
      Drug Metabolism and Disposition March 2023, 51 (3) 403-412; DOI: https://doi.org/10.1124/dmd.122.001049

  6. Mosher, Eric P.

    1. Open Access
      Achieving a Deeper Understanding of Drug Metabolism and Responses Using Single-Cell Technologies
      Abigail M. Wheeler, Colten D. Eberhard, Eric P. Mosher, Yuting Yuan, Hannah N. Wilkins, Herana Kamal Seneviratne, Benjamin C. Orsburn and Namandjé N. Bumpus
      Drug Metabolism and Disposition March 2023, 51 (3) 350-359; DOI: https://doi.org/10.1124/dmd.122.001043

N

  1. Niemi, Mikko

    1. Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A <em>in vitro</em>
      Open Access
      Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro
      Marie-Noëlle Paludetto, Mika Kurkela, Helinä Kahma, Janne T. Backman, Mikko Niemi and Anne M. Filppula
      Drug Metabolism and Disposition March 2023, 51 (3) 293-305; DOI: https://doi.org/10.1124/dmd.122.001018

O

  1. Orsburn, Benjamin C.

    1. Open Access
      Achieving a Deeper Understanding of Drug Metabolism and Responses Using Single-Cell Technologies
      Abigail M. Wheeler, Colten D. Eberhard, Eric P. Mosher, Yuting Yuan, Hannah N. Wilkins, Herana Kamal Seneviratne, Benjamin C. Orsburn and Namandjé N. Bumpus
      Drug Metabolism and Disposition March 2023, 51 (3) 350-359; DOI: https://doi.org/10.1124/dmd.122.001043

  2. Ozawa, Naoka

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

P

  1. Paludetto, Marie-Noëlle

    1. Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A <em>in vitro</em>
      Open Access
      Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro
      Marie-Noëlle Paludetto, Mika Kurkela, Helinä Kahma, Janne T. Backman, Mikko Niemi and Anne M. Filppula
      Drug Metabolism and Disposition March 2023, 51 (3) 293-305; DOI: https://doi.org/10.1124/dmd.122.001018

  2. Parrott, Neil

    1. Quantitative Cytochrome P450 3A4 Induction Risk Assessment Using Human Hepatocytes Complemented with Pregnane X Receptor-Activating Profiles
      Aynur Ekiciler, Wen Li Kelly Chen, Yan Bo, Alessandra Pugliano, Massimiliano Donzelli, Neil Parrott and Kenichi Umehara
      Drug Metabolism and Disposition March 2023, 51 (3) 276-284; DOI: https://doi.org/10.1124/dmd.122.001132

  3. Patel, Mitesh

    1. Quantification of Accurate Composition and Total Abundance of Homologous Proteins by Conserved-Plus-Surrogate Peptide Approach: Quantification of UDP Glucuronosyltransferases in Human Tissues
      Deepak Ahire, Mitesh Patel, Sujal V. Deshmukh and Bhagwat Prasad
      Drug Metabolism and Disposition March 2023, 51 (3) 285-292; DOI: https://doi.org/10.1124/dmd.122.001155

  4. Prasad, Bhagwat

    1. Quantification of Accurate Composition and Total Abundance of Homologous Proteins by Conserved-Plus-Surrogate Peptide Approach: Quantification of UDP Glucuronosyltransferases in Human Tissues
      Deepak Ahire, Mitesh Patel, Sujal V. Deshmukh and Bhagwat Prasad
      Drug Metabolism and Disposition March 2023, 51 (3) 285-292; DOI: https://doi.org/10.1124/dmd.122.001155

  5. Pugliano, Alessandra

    1. Quantitative Cytochrome P450 3A4 Induction Risk Assessment Using Human Hepatocytes Complemented with Pregnane X Receptor-Activating Profiles
      Aynur Ekiciler, Wen Li Kelly Chen, Yan Bo, Alessandra Pugliano, Massimiliano Donzelli, Neil Parrott and Kenichi Umehara
      Drug Metabolism and Disposition March 2023, 51 (3) 276-284; DOI: https://doi.org/10.1124/dmd.122.001132

Q

  1. Qiu, NaHong

    1. Contribution of UGT Enzymes to Human Drug Metabolism Stereoselectivity: A Case Study of Medetomidine, RO5263397, Propranolol, and Testosterone
      Nicolò Milani, NaHong Qiu and Stephen Fowler
      Drug Metabolism and Disposition March 2023, 51 (3) 306-317; DOI: https://doi.org/10.1124/dmd.122.001024

S

  1. Sandoval, Ruben M.

    1. Open Access
      Intravital Microscopy Reveals Unforeseen Biodistribution Within the Liver and Kidney Mechanistically Connected to the Clearance of a Bifunctional Antibody
      Amita Datta-Mannan, Bruce A. Molitoris, Yiqing Feng, Michelle M. Martinez, Ruben M. Sandoval, Robin M. Brown, Daniel Merkel, Johnny E. Croy and Kenneth W. Dunn
      Drug Metabolism and Disposition March 2023, 51 (3) 403-412; DOI: https://doi.org/10.1124/dmd.122.001049

  2. Sasaki, Yoko

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

  3. Sato, Hiromi

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

  4. Seneviratne, Herana Kamal

    1. Open Access
      Achieving a Deeper Understanding of Drug Metabolism and Responses Using Single-Cell Technologies
      Abigail M. Wheeler, Colten D. Eberhard, Eric P. Mosher, Yuting Yuan, Hannah N. Wilkins, Herana Kamal Seneviratne, Benjamin C. Orsburn and Namandjé N. Bumpus
      Drug Metabolism and Disposition March 2023, 51 (3) 350-359; DOI: https://doi.org/10.1124/dmd.122.001043
    2. Nucleoside Triphosphate Diphosphohydrolase 1 Exhibits Enzymatic Activity toward Tenofovir Diphosphate
      Herana Kamal Seneviratne
      Drug Metabolism and Disposition March 2023, 51 (3) 385-391; DOI: https://doi.org/10.1124/dmd.122.000855

  5. Shibata, Yukihiro

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

  6. Shinmi, Daisuke

    1. Comprehensive Analyses of the Intracellular and in Vivo Disposition of Fab– Small Interfering RNA Conjugate to Identify Key Issues to Improve Its in Vivo Activity
      Comprehensive Analyses of the Intracellular and in Vivo Disposition of Fab– Small Interfering RNA Conjugate to Identify Key Issues to Improve Its in Vivo Activity
      Asami Toshima, Yasuhisa Shiraishi, Daisuke Shinmi, Yoshiyuki Kagawa and Junichi Enokizono
      Drug Metabolism and Disposition March 2023, 51 (3) 338-347; DOI: https://doi.org/10.1124/dmd.122.001098

  7. Shiraishi, Yasuhisa

    1. Comprehensive Analyses of the Intracellular and in Vivo Disposition of Fab– Small Interfering RNA Conjugate to Identify Key Issues to Improve Its in Vivo Activity
      Comprehensive Analyses of the Intracellular and in Vivo Disposition of Fab– Small Interfering RNA Conjugate to Identify Key Issues to Improve Its in Vivo Activity
      Asami Toshima, Yasuhisa Shiraishi, Daisuke Shinmi, Yoshiyuki Kagawa and Junichi Enokizono
      Drug Metabolism and Disposition March 2023, 51 (3) 338-347; DOI: https://doi.org/10.1124/dmd.122.001098

T

  1. Takahashi, Keita

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

  2. Tamemoto, Yuta

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

  3. To, Elaine E.

    1. Cell and Tissue Specific Metabolism of Nucleoside and Nucleotide Drugs: Case Studies and Implications for Precision Medicine
      Elaine E. To
      Drug Metabolism and Disposition March 2023, 51 (3) 360-368; DOI: https://doi.org/10.1124/dmd.122.000856

  4. Toshima, Asami

    1. Comprehensive Analyses of the Intracellular and in Vivo Disposition of Fab– Small Interfering RNA Conjugate to Identify Key Issues to Improve Its in Vivo Activity
      Comprehensive Analyses of the Intracellular and in Vivo Disposition of Fab– Small Interfering RNA Conjugate to Identify Key Issues to Improve Its in Vivo Activity
      Asami Toshima, Yasuhisa Shiraishi, Daisuke Shinmi, Yoshiyuki Kagawa and Junichi Enokizono
      Drug Metabolism and Disposition March 2023, 51 (3) 338-347; DOI: https://doi.org/10.1124/dmd.122.001098

U

  1. Umehara, Kenichi

    1. Quantitative Cytochrome P450 3A4 Induction Risk Assessment Using Human Hepatocytes Complemented with Pregnane X Receptor-Activating Profiles
      Aynur Ekiciler, Wen Li Kelly Chen, Yan Bo, Alessandra Pugliano, Massimiliano Donzelli, Neil Parrott and Kenichi Umehara
      Drug Metabolism and Disposition March 2023, 51 (3) 276-284; DOI: https://doi.org/10.1124/dmd.122.001132

  2. Unadkat, Jashvant D.

    1. Maternal and Fetal Exposure to (-)-Δ9-tetrahydrocannabinol and Its Major Metabolites in Pregnant Mice Is Differentially Impacted by P-glycoprotein and Breast Cancer Resistance Protein
      Xin Chen, Jashvant D. Unadkat and Qingcheng Mao
      Drug Metabolism and Disposition March 2023, 51 (3) 269-275; DOI: https://doi.org/10.1124/dmd.122.001110

W

  1. Wheeler, Abigail M.

    1. Open Access
      Achieving a Deeper Understanding of Drug Metabolism and Responses Using Single-Cell Technologies
      Abigail M. Wheeler, Colten D. Eberhard, Eric P. Mosher, Yuting Yuan, Hannah N. Wilkins, Herana Kamal Seneviratne, Benjamin C. Orsburn and Namandjé N. Bumpus
      Drug Metabolism and Disposition March 2023, 51 (3) 350-359; DOI: https://doi.org/10.1124/dmd.122.001043

  2. Wilkins, Hannah N.

    1. Open Access
      Achieving a Deeper Understanding of Drug Metabolism and Responses Using Single-Cell Technologies
      Abigail M. Wheeler, Colten D. Eberhard, Eric P. Mosher, Yuting Yuan, Hannah N. Wilkins, Herana Kamal Seneviratne, Benjamin C. Orsburn and Namandjé N. Bumpus
      Drug Metabolism and Disposition March 2023, 51 (3) 350-359; DOI: https://doi.org/10.1124/dmd.122.001043

Y

  1. Yamashita, Shugo

    1. Pharmacokinetic/Pharmacodynamic Models of an Alzheimer’s Drug, Donepezil, in Rats
      Pharmacokinetic/Pharmacodynamic Models of an Alzheimer’s Drug, Donepezil, in Rats
      Akiko Kiriyama, Shunsuke Kimura and Shugo Yamashita
      Drug Metabolism and Disposition March 2023, 51 (3) 329-337; DOI: https://doi.org/10.1124/dmd.122.001061

  2. Yoshitomo, Aoi

    1. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
      Aoi Yoshitomo, Satoshi Asano, Shizuka Hozuki, Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Keita Takahashi, Yoko Sasaki, Naoka Ozawa, Michiharu Kageyama, Takeshi Iijima, Yasuhiro Kazuki, Hiromi Sato and Akihiro Hisaka
      Drug Metabolism and Disposition March 2023, 51 (3) 318-328; DOI: https://doi.org/10.1124/dmd.122.000907

  3. Yuan, Yuting

    1. Open Access
      Achieving a Deeper Understanding of Drug Metabolism and Responses Using Single-Cell Technologies
      Abigail M. Wheeler, Colten D. Eberhard, Eric P. Mosher, Yuting Yuan, Hannah N. Wilkins, Herana Kamal Seneviratne, Benjamin C. Orsburn and Namandjé N. Bumpus
      Drug Metabolism and Disposition March 2023, 51 (3) 350-359; DOI: https://doi.org/10.1124/dmd.122.001043

Z

  1. Zhong, Xiao-bo

    1. Special Section on Drug Metabolism and Precision Medicine—Editorial
      Xiao-bo Zhong and Yurong Lai
      Drug Metabolism and Disposition March 2023, 51 (3) 348-349; DOI: https://doi.org/10.1124/dmd.122.001243
Back to top

In this issue

Advertisement