Research ArticleArticle
Absorption, Metabolism, and Excretion of Taselisib (GDC-0032), a Potent β-Sparing PI3K Inhibitor in Rats, Dogs, and Humans
Shuguang Ma, Sungjoon Cho, Srikumar Sahasranaman, Weiping Zhao, Jodie Pang, Xiao Ding, Brian Dean, Bin Wang, Jerry Y. Hsu, Joseph Ware and Laurent Salphati
Drug Metabolism and Disposition April 2023, 51 (4) 436-450; DOI: https://doi.org/10.1124/dmd.122.001096
Shuguang Ma
Department of Drug Metabolism and Pharmacokinetics (S.M., S.C., W.Z., J.P., X.D., B.D., L.S.) and Department of Clinical Pharmacology (S.S., J.Y.H., J.W.), Genentech, Inc., South San Francisco, California; and XenoBiotic Laboratories (B.W.), Inc., Plainsboro, New Jersey
Sungjoon Cho
Department of Drug Metabolism and Pharmacokinetics (S.M., S.C., W.Z., J.P., X.D., B.D., L.S.) and Department of Clinical Pharmacology (S.S., J.Y.H., J.W.), Genentech, Inc., South San Francisco, California; and XenoBiotic Laboratories (B.W.), Inc., Plainsboro, New Jersey
Srikumar Sahasranaman
Department of Drug Metabolism and Pharmacokinetics (S.M., S.C., W.Z., J.P., X.D., B.D., L.S.) and Department of Clinical Pharmacology (S.S., J.Y.H., J.W.), Genentech, Inc., South San Francisco, California; and XenoBiotic Laboratories (B.W.), Inc., Plainsboro, New Jersey
Weiping Zhao
Department of Drug Metabolism and Pharmacokinetics (S.M., S.C., W.Z., J.P., X.D., B.D., L.S.) and Department of Clinical Pharmacology (S.S., J.Y.H., J.W.), Genentech, Inc., South San Francisco, California; and XenoBiotic Laboratories (B.W.), Inc., Plainsboro, New Jersey
Jodie Pang
Department of Drug Metabolism and Pharmacokinetics (S.M., S.C., W.Z., J.P., X.D., B.D., L.S.) and Department of Clinical Pharmacology (S.S., J.Y.H., J.W.), Genentech, Inc., South San Francisco, California; and XenoBiotic Laboratories (B.W.), Inc., Plainsboro, New Jersey
Xiao Ding
Department of Drug Metabolism and Pharmacokinetics (S.M., S.C., W.Z., J.P., X.D., B.D., L.S.) and Department of Clinical Pharmacology (S.S., J.Y.H., J.W.), Genentech, Inc., South San Francisco, California; and XenoBiotic Laboratories (B.W.), Inc., Plainsboro, New Jersey
Brian Dean
Department of Drug Metabolism and Pharmacokinetics (S.M., S.C., W.Z., J.P., X.D., B.D., L.S.) and Department of Clinical Pharmacology (S.S., J.Y.H., J.W.), Genentech, Inc., South San Francisco, California; and XenoBiotic Laboratories (B.W.), Inc., Plainsboro, New Jersey
Bin Wang
Department of Drug Metabolism and Pharmacokinetics (S.M., S.C., W.Z., J.P., X.D., B.D., L.S.) and Department of Clinical Pharmacology (S.S., J.Y.H., J.W.), Genentech, Inc., South San Francisco, California; and XenoBiotic Laboratories (B.W.), Inc., Plainsboro, New Jersey
Jerry Y. Hsu
Department of Drug Metabolism and Pharmacokinetics (S.M., S.C., W.Z., J.P., X.D., B.D., L.S.) and Department of Clinical Pharmacology (S.S., J.Y.H., J.W.), Genentech, Inc., South San Francisco, California; and XenoBiotic Laboratories (B.W.), Inc., Plainsboro, New Jersey
Joseph Ware
Department of Drug Metabolism and Pharmacokinetics (S.M., S.C., W.Z., J.P., X.D., B.D., L.S.) and Department of Clinical Pharmacology (S.S., J.Y.H., J.W.), Genentech, Inc., South San Francisco, California; and XenoBiotic Laboratories (B.W.), Inc., Plainsboro, New Jersey
Laurent Salphati
Department of Drug Metabolism and Pharmacokinetics (S.M., S.C., W.Z., J.P., X.D., B.D., L.S.) and Department of Clinical Pharmacology (S.S., J.Y.H., J.W.), Genentech, Inc., South San Francisco, California; and XenoBiotic Laboratories (B.W.), Inc., Plainsboro, New Jersey
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Research ArticleArticle
Absorption, Metabolism, and Excretion of Taselisib
Shuguang Ma, Sungjoon Cho, Srikumar Sahasranaman, Weiping Zhao, Jodie Pang, Xiao Ding, Brian Dean, Bin Wang, Jerry Y. Hsu, Joseph Ware and Laurent Salphati
Drug Metabolism and Disposition April 1, 2023, 51 (4) 436-450; DOI: https://doi.org/10.1124/dmd.122.001096
Research ArticleArticle
Absorption, Metabolism, and Excretion of Taselisib
Shuguang Ma, Sungjoon Cho, Srikumar Sahasranaman, Weiping Zhao, Jodie Pang, Xiao Ding, Brian Dean, Bin Wang, Jerry Y. Hsu, Joseph Ware and Laurent Salphati
Drug Metabolism and Disposition April 1, 2023, 51 (4) 436-450; DOI: https://doi.org/10.1124/dmd.122.001096
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