Table of Contents

Articles

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  Characterization of Enzymes Involved in Nintedanib Metabolism in Humans

  Shimon Nakashima, Rei Sato, Tatsuki Fukami, Takashi Kudo, Shiori Hashiba, Gaku Morinaga, Masataka Nakano, Eva Ludwig-Schwellinger, Akiko Matsui, Naoki Ishiguro, Thomas Ebner and Miki Nakajima

  Drug Metabolism and Disposition June 2023, 51 (6) 733-742; DOI: https://doi.org/10.1124/dmd.122.001113
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  A Physiologically-Based Pharmacokinetic Model for Cannabidiol in Healthy Adults, Hepatically-Impaired Adults, and Children

  Sumit Bansal, Mayur K. Ladumor, Mary F. Paine and Jashvant D. Unadkat

  Drug Metabolism and Disposition June 2023, 51 (6) 743-752; DOI: https://doi.org/10.1124/dmd.122.001128
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  Complex Metabolism of the Novel Neurosteroid, Ganaxolone, in Humans: A Unique Challenge for Metabolites in Safety Testing Assessment

  William L. Fitch, Steven Smith, Michael Saporito, Gregory Busse, Mingbao Zhang, Julie Ren, Michael E. Fitzsimmons, Ping Yi, Stephen English, Adam Carter and Thomas A. Baillie

  Drug Metabolism and Disposition June 2023, 51 (6) 753-763; DOI: https://doi.org/10.1124/dmd.122.001218
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  Inactivation of Human Aldehyde Oxidase by Small Sulfhydryl-Containing Reducing Agents

  Mariam Esmaeeli, Manfred Nimtz, Lothar Jänsch, Lloyd W. Ruddock and Silke Leimkühler

  Drug Metabolism and Disposition June 2023, 51 (6) 764-770; DOI: https://doi.org/10.1124/dmd.122.001244
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  Mechanistic Study of Icaritin-Induced Inactivation of Cytochrome P450 2C9

  Xiang Chen, Luyao Han, Yulin Zhao, Haoyan Huang, He Pan, Chenmeng Zhang, Huili Chen, Shanliang Sun, Sihui Yao, Xijing Chen and Yongjie Zhang

  Drug Metabolism and Disposition June 2023, 51 (6) 771-781; DOI: https://doi.org/10.1124/dmd.122.001245
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  Mechanistic Investigation of the Time-Dependent Aldehyde Oxidase Inhibitor Hydralazine

  J. Paige Barnes, Shaoyun M. Yang, Taylor S. Thompson, Caithlyne M. Guevarra, Shaniya S. Pleasant, Tri Q. Do and Rachel D. Crouch

  Drug Metabolism and Disposition June 2023, 51 (6) 782-791; DOI: https://doi.org/10.1124/dmd.123.001257