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Index by author

September 01, 2023; Volume 51,Issue 9

A

  1. Aoki, Yasunori

    1. A 20-Year Research Overview: Quantitative Prediction of Hepatic Clearance Using the In Vitro-In Vivo Extrapolation Approach Based on Physiologically Based Pharmacokinetic Modeling and Extended Clearance Concept
      Yuichi Sugiyama and Yasunori Aoki
      Drug Metabolism and Disposition September 2023, 51 (9) 1067-1076; DOI: https://doi.org/10.1124/dmd.123.001344
    2. Predicting In Vivo Target Occupancy (TO) Profiles via Physiologically Based Pharmacokinetic–TO Modeling of Warfarin Pharmacokinetics in Blood: Importance of Low Dose Data and Prediction of Stereoselective Target Interactions
      Wooin Lee, Min-Soo Kim, Jiyoung Kim, Yasunori Aoki and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2023, 51 (9) 1145-1156; DOI: https://doi.org/10.1124/dmd.122.000968

  2. Arakawa, Hiroshi

    1. Emerging Roles of Uremic Toxins and Inflammatory Cytokines in the Alteration of Hepatic Drug Disposition in Patients with Kidney Dysfunction
      Hiroshi Arakawa and Yukio Kato
      Drug Metabolism and Disposition September 2023, 51 (9) 1127-1135; DOI: https://doi.org/10.1124/dmd.122.000967
    2. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

B

  1. Backes, Wayne L.

    1. The Influence of Lipid Microdomain Heterogeneity on Protein-Protein Interactions: Proteomic Analysis of Co-Immunoprecipitated Binding Partners of P450 1A2 and P450 3A in Rat Liver Microsomes
      James R. Reed, Jessie J. Guidry, Marilyn Eyer and Wayne L. Backes
      Drug Metabolism and Disposition September 2023, 51 (9) 1196-1206; DOI: https://doi.org/10.1124/dmd.123.001287

  2. Banner, Jytte

    1. Sex- and Lifestyle-Related Factors are Associated with Altered Hepatic CYP Protein Levels in People Diagnosed with Mental Disorders
      Kata W. Pedersen, Jakob Hansen, Jytte Banner, Jørgen B. Hasselstrøm and Jakob R. Jornil
      Drug Metabolism and Disposition September 2023, 51 (9) 1169-1176; DOI: https://doi.org/10.1124/dmd.122.001125

  3. Blumberg, Bruce

    1. Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Fang Wang, Jingwei Liu, Rebecca Hernandez, Se-Hyung Park, Ying-Jing Lai, Shuxia Wang, Bruce Blumberg and Changcheng Zhou
      Drug Metabolism and Disposition September 2023, 51 (9) 1207-1215; DOI: https://doi.org/10.1124/dmd.123.001311

C

  1. Chan, Grace Hoyee

    1. Evaluation of the Selectivity of Several Organic Anion Transporting Polypeptide 1B Biomarkers Using Relative Activity Factor Method
      Grace Hoyee Chan, Robert Houle, Jinghui Zhang, Ravi Katwaru, Yang Li and Xiaoyan Chu
      Drug Metabolism and Disposition September 2023, 51 (9) 1089-1104; DOI: https://doi.org/10.1124/dmd.122.000972

  2. Cherrington, Nathan J.

    1. In Vitro and In Vivo Models for Drug Transport Across the Blood-Testis Barrier
      Raymond K. Hau, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition September 2023, 51 (9) 1157-1168; DOI: https://doi.org/10.1124/dmd.123.001288

  3. Chu, Xiaoyan

    1. Evaluation of the Selectivity of Several Organic Anion Transporting Polypeptide 1B Biomarkers Using Relative Activity Factor Method
      Grace Hoyee Chan, Robert Houle, Jinghui Zhang, Ravi Katwaru, Yang Li and Xiaoyan Chu
      Drug Metabolism and Disposition September 2023, 51 (9) 1089-1104; DOI: https://doi.org/10.1124/dmd.122.000972

E

  1. Eyer, Marilyn

    1. The Influence of Lipid Microdomain Heterogeneity on Protein-Protein Interactions: Proteomic Analysis of Co-Immunoprecipitated Binding Partners of P450 1A2 and P450 3A in Rat Liver Microsomes
      James R. Reed, Jessie J. Guidry, Marilyn Eyer and Wayne L. Backes
      Drug Metabolism and Disposition September 2023, 51 (9) 1196-1206; DOI: https://doi.org/10.1124/dmd.123.001287

F

  1. Fukami, Tatsuki

    1. In Vitro Evaluation of the Reductase Activities of Human AKR1C3 Allelic Variants
      Shiori Takano, Tatsuki Fukami, Hiroyuki Ichida, Kohei Suzuki, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition September 2023, 51 (9) 1188-1195; DOI: https://doi.org/10.1124/dmd.123.001264

G

  1. Guidry, Jessie J.

    1. The Influence of Lipid Microdomain Heterogeneity on Protein-Protein Interactions: Proteomic Analysis of Co-Immunoprecipitated Binding Partners of P450 1A2 and P450 3A in Rat Liver Microsomes
      James R. Reed, Jessie J. Guidry, Marilyn Eyer and Wayne L. Backes
      Drug Metabolism and Disposition September 2023, 51 (9) 1196-1206; DOI: https://doi.org/10.1124/dmd.123.001287

H

  1. Hansen, Jakob

    1. Sex- and Lifestyle-Related Factors are Associated with Altered Hepatic CYP Protein Levels in People Diagnosed with Mental Disorders
      Kata W. Pedersen, Jakob Hansen, Jytte Banner, Jørgen B. Hasselstrøm and Jakob R. Jornil
      Drug Metabolism and Disposition September 2023, 51 (9) 1169-1176; DOI: https://doi.org/10.1124/dmd.122.001125

  2. Hasselstrøm, Jørgen B.

    1. Sex- and Lifestyle-Related Factors are Associated with Altered Hepatic CYP Protein Levels in People Diagnosed with Mental Disorders
      Kata W. Pedersen, Jakob Hansen, Jytte Banner, Jørgen B. Hasselstrøm and Jakob R. Jornil
      Drug Metabolism and Disposition September 2023, 51 (9) 1169-1176; DOI: https://doi.org/10.1124/dmd.122.001125

  3. Hau, Raymond K.

    1. In Vitro and In Vivo Models for Drug Transport Across the Blood-Testis Barrier
      Raymond K. Hau, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition September 2023, 51 (9) 1157-1168; DOI: https://doi.org/10.1124/dmd.123.001288

  4. Hernandez, Rebecca

    1. Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Fang Wang, Jingwei Liu, Rebecca Hernandez, Se-Hyung Park, Ying-Jing Lai, Shuxia Wang, Bruce Blumberg and Changcheng Zhou
      Drug Metabolism and Disposition September 2023, 51 (9) 1207-1215; DOI: https://doi.org/10.1124/dmd.123.001311

  5. Higuchi, Daichi

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  6. Houle, Robert

    1. Evaluation of the Selectivity of Several Organic Anion Transporting Polypeptide 1B Biomarkers Using Relative Activity Factor Method
      Grace Hoyee Chan, Robert Houle, Jinghui Zhang, Ravi Katwaru, Yang Li and Xiaoyan Chu
      Drug Metabolism and Disposition September 2023, 51 (9) 1089-1104; DOI: https://doi.org/10.1124/dmd.122.000972

I

  1. Ichida, Hiroyuki

    1. In Vitro Evaluation of the Reductase Activities of Human AKR1C3 Allelic Variants
      Shiori Takano, Tatsuki Fukami, Hiroyuki Ichida, Kohei Suzuki, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition September 2023, 51 (9) 1188-1195; DOI: https://doi.org/10.1124/dmd.123.001264

  2. Ishiguro, Naoki

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  3. Ito, Kiyomi

    1. Quantitative Consideration of Clinical Increases in Serum Creatinine Caused by Renal Transporter Inhibition
      Tomohisa Nakada, Toshiyuki Kudo and Kiyomi Ito
      Drug Metabolism and Disposition September 2023, 51 (9) 1114-1126; DOI: https://doi.org/10.1124/dmd.122.000969

  4. Izumi, Saki

    1. Preincubation Time-Dependent, Long-Lasting Inhibition of Drug Transporters and Impact on the Prediction of Drug−Drug Interactions
      Yoshitane Nozaki and Saki Izumi
      Drug Metabolism and Disposition September 2023, 51 (9) 1077-1088; DOI: https://doi.org/10.1124/dmd.122.000970

J

  1. Jianmongkol, Suree

    1. The Potentially Significant Role of CYP3A-Mediated Oxidative Metabolism of Dabigatran Etexilate and Its Intermediate Metabolites in Drug-Drug Interaction Assessments Using Microdose Dabigatran Etexilate
      Udomsak Udomnilobol, Suree Jianmongkol and Thomayant Prueksaritanont
      Drug Metabolism and Disposition September 2023, 51 (9) 1216-1226; DOI: https://doi.org/10.1124/dmd.123.001353

  2. Jimbo, Yoichi

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  3. Jornil, Jakob R.

    1. Sex- and Lifestyle-Related Factors are Associated with Altered Hepatic CYP Protein Levels in People Diagnosed with Mental Disorders
      Kata W. Pedersen, Jakob Hansen, Jytte Banner, Jørgen B. Hasselstrøm and Jakob R. Jornil
      Drug Metabolism and Disposition September 2023, 51 (9) 1169-1176; DOI: https://doi.org/10.1124/dmd.122.001125

K

  1. Kadoguchi, Moeno

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  2. Kato, Yukio

    1. Emerging Roles of Uremic Toxins and Inflammatory Cytokines in the Alteration of Hepatic Drug Disposition in Patients with Kidney Dysfunction
      Hiroshi Arakawa and Yukio Kato
      Drug Metabolism and Disposition September 2023, 51 (9) 1127-1135; DOI: https://doi.org/10.1124/dmd.122.000967

  3. Katwaru, Ravi

    1. Evaluation of the Selectivity of Several Organic Anion Transporting Polypeptide 1B Biomarkers Using Relative Activity Factor Method
      Grace Hoyee Chan, Robert Houle, Jinghui Zhang, Ravi Katwaru, Yang Li and Xiaoyan Chu
      Drug Metabolism and Disposition September 2023, 51 (9) 1089-1104; DOI: https://doi.org/10.1124/dmd.122.000972

  4. Kim, Jiyoung

    1. Predicting In Vivo Target Occupancy (TO) Profiles via Physiologically Based Pharmacokinetic–TO Modeling of Warfarin Pharmacokinetics in Blood: Importance of Low Dose Data and Prediction of Stereoselective Target Interactions
      Wooin Lee, Min-Soo Kim, Jiyoung Kim, Yasunori Aoki and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2023, 51 (9) 1145-1156; DOI: https://doi.org/10.1124/dmd.122.000968

  5. Kim, Min-Soo

    1. Predicting In Vivo Target Occupancy (TO) Profiles via Physiologically Based Pharmacokinetic–TO Modeling of Warfarin Pharmacokinetics in Blood: Importance of Low Dose Data and Prediction of Stereoselective Target Interactions
      Wooin Lee, Min-Soo Kim, Jiyoung Kim, Yasunori Aoki and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2023, 51 (9) 1145-1156; DOI: https://doi.org/10.1124/dmd.122.000968

  6. Kitagawa, Fumihiko

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  7. Kondo, Masayuki

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  8. Kudo, Takashi

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  9. Kudo, Toshiyuki

    1. Quantitative Consideration of Clinical Increases in Serum Creatinine Caused by Renal Transporter Inhibition
      Tomohisa Nakada, Toshiyuki Kudo and Kiyomi Ito
      Drug Metabolism and Disposition September 2023, 51 (9) 1114-1126; DOI: https://doi.org/10.1124/dmd.122.000969

  10. Kusuhara, Hiroyuki

    1. Progress in the Quantitative Assessment of Transporter-Mediated Drug–Drug Interactions Using Endogenous Substrates in Clinical Studies
      Tatsuki Mochizuki and Hiroyuki Kusuhara
      Drug Metabolism and Disposition September 2023, 51 (9) 1105-1113; DOI: https://doi.org/10.1124/dmd.123.001285

L

  1. Lai, Ying-Jing

    1. Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Fang Wang, Jingwei Liu, Rebecca Hernandez, Se-Hyung Park, Ying-Jing Lai, Shuxia Wang, Bruce Blumberg and Changcheng Zhou
      Drug Metabolism and Disposition September 2023, 51 (9) 1207-1215; DOI: https://doi.org/10.1124/dmd.123.001311

  2. Lai, Yurong

    1. Special Section on Mechanism-Based Predictive Methods in Drug Discovery and Development—Editorial
      Yurong Lai and Xiao-bo Zhong
      Drug Metabolism and Disposition September 2023, 51 (9) 1064-1066; DOI: https://doi.org/10.1124/dmd.123.001456

  3. Lee, Wooin

    1. Predicting In Vivo Target Occupancy (TO) Profiles via Physiologically Based Pharmacokinetic–TO Modeling of Warfarin Pharmacokinetics in Blood: Importance of Low Dose Data and Prediction of Stereoselective Target Interactions
      Wooin Lee, Min-Soo Kim, Jiyoung Kim, Yasunori Aoki and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2023, 51 (9) 1145-1156; DOI: https://doi.org/10.1124/dmd.122.000968

  4. Li, Yang

    1. Evaluation of the Selectivity of Several Organic Anion Transporting Polypeptide 1B Biomarkers Using Relative Activity Factor Method
      Grace Hoyee Chan, Robert Houle, Jinghui Zhang, Ravi Katwaru, Yang Li and Xiaoyan Chu
      Drug Metabolism and Disposition September 2023, 51 (9) 1089-1104; DOI: https://doi.org/10.1124/dmd.122.000972

  5. Liu, Jingwei

    1. Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Fang Wang, Jingwei Liu, Rebecca Hernandez, Se-Hyung Park, Ying-Jing Lai, Shuxia Wang, Bruce Blumberg and Changcheng Zhou
      Drug Metabolism and Disposition September 2023, 51 (9) 1207-1215; DOI: https://doi.org/10.1124/dmd.123.001311

M

  1. Mae, Shin-ichi

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  2. Maeda, Kazuya

    1. Quantitative Prediction of Intestinal Absorption of Drugs from In Vitro Study: Utilization of Differentiated Intestinal Epithelial Cells Derived from Intestinal Stem Cells at Crypts
      Kazuya Maeda
      Drug Metabolism and Disposition September 2023, 51 (9) 1136-1144; DOI: https://doi.org/10.1124/dmd.122.000966

  3. Mochizuki, Tatsuki

    1. Progress in the Quantitative Assessment of Transporter-Mediated Drug–Drug Interactions Using Endogenous Substrates in Clinical Studies
      Tatsuki Mochizuki and Hiroyuki Kusuhara
      Drug Metabolism and Disposition September 2023, 51 (9) 1105-1113; DOI: https://doi.org/10.1124/dmd.123.001285

  4. Morinaga, Gaku

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

N

  1. Nakada, Tomohisa

    1. Quantitative Consideration of Clinical Increases in Serum Creatinine Caused by Renal Transporter Inhibition
      Tomohisa Nakada, Toshiyuki Kudo and Kiyomi Ito
      Drug Metabolism and Disposition September 2023, 51 (9) 1114-1126; DOI: https://doi.org/10.1124/dmd.122.000969

  2. Nakajima, Miki

    1. In Vitro Evaluation of the Reductase Activities of Human AKR1C3 Allelic Variants
      Shiori Takano, Tatsuki Fukami, Hiroyuki Ichida, Kohei Suzuki, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition September 2023, 51 (9) 1188-1195; DOI: https://doi.org/10.1124/dmd.123.001264

  3. Nakano, Masataka

    1. In Vitro Evaluation of the Reductase Activities of Human AKR1C3 Allelic Variants
      Shiori Takano, Tatsuki Fukami, Hiroyuki Ichida, Kohei Suzuki, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition September 2023, 51 (9) 1188-1195; DOI: https://doi.org/10.1124/dmd.123.001264

  4. Nakazono, Yuya

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  5. Nozaki, Yoshitane

    1. Preincubation Time-Dependent, Long-Lasting Inhibition of Drug Transporters and Impact on the Prediction of Drug−Drug Interactions
      Yoshitane Nozaki and Saki Izumi
      Drug Metabolism and Disposition September 2023, 51 (9) 1077-1088; DOI: https://doi.org/10.1124/dmd.122.000970

O

  1. Osafune, Kenji

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

P

  1. Park, Se-Hyung

    1. Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Fang Wang, Jingwei Liu, Rebecca Hernandez, Se-Hyung Park, Ying-Jing Lai, Shuxia Wang, Bruce Blumberg and Changcheng Zhou
      Drug Metabolism and Disposition September 2023, 51 (9) 1207-1215; DOI: https://doi.org/10.1124/dmd.123.001311

  2. Pedersen, Kata W.

    1. Sex- and Lifestyle-Related Factors are Associated with Altered Hepatic CYP Protein Levels in People Diagnosed with Mental Disorders
      Kata W. Pedersen, Jakob Hansen, Jytte Banner, Jørgen B. Hasselstrøm and Jakob R. Jornil
      Drug Metabolism and Disposition September 2023, 51 (9) 1169-1176; DOI: https://doi.org/10.1124/dmd.122.001125

  3. Prueksaritanont, Thomayant

    1. The Potentially Significant Role of CYP3A-Mediated Oxidative Metabolism of Dabigatran Etexilate and Its Intermediate Metabolites in Drug-Drug Interaction Assessments Using Microdose Dabigatran Etexilate
      Udomsak Udomnilobol, Suree Jianmongkol and Thomayant Prueksaritanont
      Drug Metabolism and Disposition September 2023, 51 (9) 1216-1226; DOI: https://doi.org/10.1124/dmd.123.001353

R

  1. Reed, James R.

    1. The Influence of Lipid Microdomain Heterogeneity on Protein-Protein Interactions: Proteomic Analysis of Co-Immunoprecipitated Binding Partners of P450 1A2 and P450 3A in Rat Liver Microsomes
      James R. Reed, Jessie J. Guidry, Marilyn Eyer and Wayne L. Backes
      Drug Metabolism and Disposition September 2023, 51 (9) 1196-1206; DOI: https://doi.org/10.1124/dmd.123.001287

S

  1. Saito, Asami

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  2. Sugiyama, Yuichi

    1. A 20-Year Research Overview: Quantitative Prediction of Hepatic Clearance Using the In Vitro-In Vivo Extrapolation Approach Based on Physiologically Based Pharmacokinetic Modeling and Extended Clearance Concept
      Yuichi Sugiyama and Yasunori Aoki
      Drug Metabolism and Disposition September 2023, 51 (9) 1067-1076; DOI: https://doi.org/10.1124/dmd.123.001344
    2. Predicting In Vivo Target Occupancy (TO) Profiles via Physiologically Based Pharmacokinetic–TO Modeling of Warfarin Pharmacokinetics in Blood: Importance of Low Dose Data and Prediction of Stereoselective Target Interactions
      Wooin Lee, Min-Soo Kim, Jiyoung Kim, Yasunori Aoki and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2023, 51 (9) 1145-1156; DOI: https://doi.org/10.1124/dmd.122.000968

  3. Suzuki, Kohei

    1. In Vitro Evaluation of the Reductase Activities of Human AKR1C3 Allelic Variants
      Shiori Takano, Tatsuki Fukami, Hiroyuki Ichida, Kohei Suzuki, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition September 2023, 51 (9) 1188-1195; DOI: https://doi.org/10.1124/dmd.123.001264

T

  1. Takahashi, Etsushi

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  2. Takahashi, Ryo

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  3. Takano, Shiori

    1. In Vitro Evaluation of the Reductase Activities of Human AKR1C3 Allelic Variants
      Shiori Takano, Tatsuki Fukami, Hiroyuki Ichida, Kohei Suzuki, Masataka Nakano and Miki Nakajima
      Drug Metabolism and Disposition September 2023, 51 (9) 1188-1195; DOI: https://doi.org/10.1124/dmd.123.001264

  4. Takatani, Masahito

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

  5. Tamai, Ikumi

    1. Open Access
      Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
      Naoki Ishiguro, Etsushi Takahashi, Hiroshi Arakawa, Asami Saito, Fumihiko Kitagawa, Masayuki Kondo, Gaku Morinaga, Masahito Takatani, Ryo Takahashi, Takashi Kudo, Shin-ichi Mae, Moeno Kadoguchi, Daichi Higuchi, Yuya Nakazono, Ikumi Tamai, Kenji Osafune and Yoichi Jimbo
      Drug Metabolism and Disposition September 2023, 51 (9) 1177-1187; DOI: https://doi.org/10.1124/dmd.122.001171

U

  1. Udomnilobol, Udomsak

    1. The Potentially Significant Role of CYP3A-Mediated Oxidative Metabolism of Dabigatran Etexilate and Its Intermediate Metabolites in Drug-Drug Interaction Assessments Using Microdose Dabigatran Etexilate
      Udomsak Udomnilobol, Suree Jianmongkol and Thomayant Prueksaritanont
      Drug Metabolism and Disposition September 2023, 51 (9) 1216-1226; DOI: https://doi.org/10.1124/dmd.123.001353

W

  1. Wang, Fang

    1. Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Fang Wang, Jingwei Liu, Rebecca Hernandez, Se-Hyung Park, Ying-Jing Lai, Shuxia Wang, Bruce Blumberg and Changcheng Zhou
      Drug Metabolism and Disposition September 2023, 51 (9) 1207-1215; DOI: https://doi.org/10.1124/dmd.123.001311

  2. Wang, Shuxia

    1. Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Fang Wang, Jingwei Liu, Rebecca Hernandez, Se-Hyung Park, Ying-Jing Lai, Shuxia Wang, Bruce Blumberg and Changcheng Zhou
      Drug Metabolism and Disposition September 2023, 51 (9) 1207-1215; DOI: https://doi.org/10.1124/dmd.123.001311

  3. Wright, Stephen H.

    1. In Vitro and In Vivo Models for Drug Transport Across the Blood-Testis Barrier
      Raymond K. Hau, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition September 2023, 51 (9) 1157-1168; DOI: https://doi.org/10.1124/dmd.123.001288

Z

  1. Zhang, Jinghui

    1. Evaluation of the Selectivity of Several Organic Anion Transporting Polypeptide 1B Biomarkers Using Relative Activity Factor Method
      Grace Hoyee Chan, Robert Houle, Jinghui Zhang, Ravi Katwaru, Yang Li and Xiaoyan Chu
      Drug Metabolism and Disposition September 2023, 51 (9) 1089-1104; DOI: https://doi.org/10.1124/dmd.122.000972

  2. Zhong, Xiao-bo

    1. Special Section on Mechanism-Based Predictive Methods in Drug Discovery and Development—Editorial
      Yurong Lai and Xiao-bo Zhong
      Drug Metabolism and Disposition September 2023, 51 (9) 1064-1066; DOI: https://doi.org/10.1124/dmd.123.001456

  3. Zhou, Changcheng

    1. Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
      Fang Wang, Jingwei Liu, Rebecca Hernandez, Se-Hyung Park, Ying-Jing Lai, Shuxia Wang, Bruce Blumberg and Changcheng Zhou
      Drug Metabolism and Disposition September 2023, 51 (9) 1207-1215; DOI: https://doi.org/10.1124/dmd.123.001311
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