The Potentially Significant Role of CYP3A-Mediated Oxidative Metabolism of Dabigatran Etexilate and Its Intermediate Metabolites in Drug-Drug Interaction Assessments Using Microdose Dabigatran Etexilate

Udomsak Udomnilobol; Suree Jianmongkol; Thomayant Prueksaritanont

doi:10.1124/dmd.123.001353

Research ArticleArticle

The Potentially Significant Role of CYP3A-Mediated Oxidative Metabolism of Dabigatran Etexilate and Its Intermediate Metabolites in Drug-Drug Interaction Assessments Using Microdose Dabigatran Etexilate

Udomsak Udomnilobol, Suree Jianmongkol and Thomayant Prueksaritanont

Drug Metabolism and Disposition September 2023, 51 (9) 1216-1226; DOI: https://doi.org/10.1124/dmd.123.001353

Udomsak Udomnilobol

Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences (U.U., S.J.) and Chulalongkorn University Drug Discovery and Drug Development Research Center (Chula4DR) (U.U., T.P.), Chulalongkorn University, Bangkok, Thailand

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Suree Jianmongkol

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Thomayant Prueksaritanont

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Drug Metabolism and Disposition

Vol. 51, Issue 9

1 Sep 2023

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Research ArticleArticle

CYP3A-Mediated Oxidation of DABE and BIBR0951

Udomsak Udomnilobol, Suree Jianmongkol and Thomayant Prueksaritanont

Drug Metabolism and Disposition September 1, 2023, 51 (9) 1216-1226; DOI: https://doi.org/10.1124/dmd.123.001353

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Research ArticleArticle

CYP3A-Mediated Oxidation of DABE and BIBR0951

Udomsak Udomnilobol, Suree Jianmongkol and Thomayant Prueksaritanont

Drug Metabolism and Disposition September 1, 2023, 51 (9) 1216-1226; DOI: https://doi.org/10.1124/dmd.123.001353

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