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Drug Metabolism & Disposition

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Table of Contents

March 01, 1979; Volume 7,Issue 2
  • You have access
    Studies of the mechanism of the substrate activation of glucuronyltransferase by 7-hydroxychlorpromazine.
    J V Dingell and N Sossi
    Drug Metabolism and Disposition March 1979, 7 (2) 61-64;
  • You have access
    The metabolism of N-hydroxyphentermine by rat liver microsomes.
    C Y Sum and A K Cho
    Drug Metabolism and Disposition March 1979, 7 (2) 65-69;
  • You have access
    Foreign compound metabolism by isolated cells from rabbit lung.
    T R Devereux, G E Hook and J R Fouts
    Drug Metabolism and Disposition March 1979, 7 (2) 70-75;
  • You have access
    Biotransformation of 4'-ethynl-2-fluorobiphenyl in the rat. In vitro and in vivo studies.
    H R Sullivan, P Roffey and R E McMahon
    Drug Metabolism and Disposition March 1979, 7 (2) 76-80;
  • You have access
    Disposition of flunisolide in the rat, mouse, dog, rhesus monkey, and cynomolgus monkey.
    N I Chu, B A Amos, L Tökés, M L Maddox, S B Matin, K M Hama, J W Patterson, P J Wagner, J P Bell and M D Chaplin
    Drug Metabolism and Disposition March 1979, 7 (2) 81-89;
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    Disposition of the pulmonary toxin, bleomycin.
    W M Tom and M R Montgomery
    Drug Metabolism and Disposition March 1979, 7 (2) 90-93;
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    Metabolism and disposition by the rat of 35S-sulfadiazine alone and in the presence of trimethoprim.
    J L Woolley and C W Sigel
    Drug Metabolism and Disposition March 1979, 7 (2) 94-99;
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    A pharmacokinetic model for enterohepatic recirculation in the rat: phenolphthalein, a model drug.
    W A Colburn, P C Hirom, R J Parker and P Milburn
    Drug Metabolism and Disposition March 1979, 7 (2) 100-102;
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    Re-evaluation of the antimineralocorticoid effect of the spironolactone metabolite, canrenone, from plasma concentrations determined by a new high-pressure liquid-chromatographic method.
    C G Dahlöf, P Lundborg, B A Persson and C G Regårdh
    Drug Metabolism and Disposition March 1979, 7 (2) 103-107;
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    Pharmacokinetics and analgesic effect of pethidine (meperidine) and its metabolites in the rat.
    B E Dahlström, L K Paalzow, C Lindberg and C Bogentoft
    Drug Metabolism and Disposition March 1979, 7 (2) 108-112;
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    Effect of ethanol on the renal excretion and metabolism of choline in the isolated perfused rat kidney.
    M Acara
    Drug Metabolism and Disposition March 1979, 7 (2) 113-117;
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In this issue

Drug Metabolism and Disposition
Vol. 7, Issue 2
1 Mar 1979
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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