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Drug Metabolism & Disposition

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Table of Contents

March 01, 1980; Volume 8,Issue 2
  • You have access
    Studies on the disposition of phencyclidine in mice.
    B R Martin, W C Vincek and R L Balster
    Drug Metabolism and Disposition March 1980, 8 (2) 49-54;
  • You have access
    Distribution of l-alpha-[2-3H]acetylmethadol and its metabolites in maternal and fetal rat tissues.
    M Man, S O Alozie, L A Woods, B R Martin and L S Harris
    Drug Metabolism and Disposition March 1980, 8 (2) 55-59;
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    Disposition of 9-beta-D-arabinofuranosyl-2-fluoroadenine in mice, dogs, and monkeys.
    S M El Dareer, R F Struck, K F Tillery, L M Rose, R W Brockman, J A Montgomery and D L Hill
    Drug Metabolism and Disposition March 1980, 8 (2) 60-63;
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    Pharmacokinetics of saccharin in the rat. Renal clearance in vivo and in the isolated perfused kidney.
    I Bekersky, W J Poynor and W A Colburn
    Drug Metabolism and Disposition March 1980, 8 (2) 64-67;
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    Metabolism and biliary excretion of benzo[a]pyrene 4,5-oxide in the rat.
    J L Plummer, B R Smith, L M Ball and J R Bend
    Drug Metabolism and Disposition March 1980, 8 (2) 68-72;
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    Studies in the rabbit on 3-methyltriazolophthalazine, an acetylated metabolite of hydralazine. Evidence for an alternative route of formation.
    T Talseth, K D Haegele and J L McNay
    Drug Metabolism and Disposition March 1980, 8 (2) 73-76;
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    Ethchlorvynol: potential of metabolites for adverse effects in man.
    J P Horwitz, W Brukwinski, J Treisman, D Andrzejewski, E B Hills, H L Chung and C Y Wang
    Drug Metabolism and Disposition March 1980, 8 (2) 77-83;
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    Determination of a urinary epoxide metabolite of alclofenac in man.
    J A Slack and A W Ford-Hutchinson
    Drug Metabolism and Disposition March 1980, 8 (2) 84-86;
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    In vivo metabolism of clebopride in three animal species and in man.
    J Segura, O M Bakke, G Huizing and A H Beckett
    Drug Metabolism and Disposition March 1980, 8 (2) 87-92;
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    Glutathione-dependent dechlorination of chloramphenicol by cytosol of rat liver.
    J L Martin, J W George and L R Pohl
    Drug Metabolism and Disposition March 1980, 8 (2) 93-97;
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    Initial characterization of drug-metabolizing systems in the liver of the Northern pike, Esox lucius.
    L Balk, J Meijer, J Seidegärd, R Morgenstein and J W Depierre
    Drug Metabolism and Disposition March 1980, 8 (2) 98-103;
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    Stereoselective hydroxylation of hexobarbital enantiomers by rat liver microsomes.
    K Miyano, Y Fujii and S Toki
    Drug Metabolism and Disposition March 1980, 8 (2) 104-110;
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    Preparation of four optical isomers of hydroxylated hexobarbital and activities of 3-hydroxyhexobarbital dehydrogenase from guinea pig and rabbit liver.
    K Miyano and S Toki
    Drug Metabolism and Disposition March 1980, 8 (2) 111-114;
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    1-(3-Hydroxycyclohexyl)-1-phenyl-3-(1-pyrrolidinyl)-1-propanol, a procyclidine metabolite.
    G Paeme, W Sonck, D Tourwé, R Grimée and A Vercruysse
    Drug Metabolism and Disposition March 1980, 8 (2) 115-116;
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    Aldehyde conjugates.
    P G Dayton
    Drug Metabolism and Disposition March 1980, 8 (2) 120;
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In this issue

Drug Metabolism and Disposition
Vol. 8, Issue 2
1 Mar 1980
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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