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Drug Metabolism & Disposition

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Index by author

May 01, 1980; Volume 8,Issue 3
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Al-Turk, W A

    1. You have access
      Effect of acute and chronic estrone, estradiol, and estriol treatment on hepatic, pulmonary, and intestinal mixed-function mon-oxygenase activities in female rats.
      W A Al-Turk, S J Stohs and E B Roche
      Drug Metabolism and Disposition May 1980, 8 (3) 143-146; DOI: https://doi.org/10.1124/dmd.8.3.143
  2. Andrews, P A

    1. You have access
      Facile and definitive determination of human adriamycin and daunoribicin metabolites by high-pressure liquid chromatography.
      P A Andrews, D E Brenner, F T Chou, H Kubo and N R Bachur
      Drug Metabolism and Disposition May 1980, 8 (3) 152-156; DOI: https://doi.org/10.1124/dmd.8.3.152
  3. Arison, B H

    1. You have access
      Identification of a glutathione conjugate of cambendazole formed in the presence of liver microsomes.
      D E Wolf, J A VandenHeuvel, T R Tyler, R W Walker, F R Koniuszy, V Gruber, B H Arison, A Rosegay, T A Jacob and F J Wolf
      Drug Metabolism and Disposition May 1980, 8 (3) 131-136; DOI: https://doi.org/10.1124/dmd.8.3.131
    2. You have access
      The metabolic disposition of (S)-2-(3-tert-butylamino-2-hydroxypropoxy)-3-cyanopyridine in rats, dogs, and humans.
      S Vickers, C A Duncan, B H Arison, R O Davies, R Ferguson and A G Zacchei
      Drug Metabolism and Disposition May 1980, 8 (3) 163-167; DOI: https://doi.org/10.1124/dmd.8.3.163

B

  1. Bachur, N R

    1. You have access
      Facile and definitive determination of human adriamycin and daunoribicin metabolites by high-pressure liquid chromatography.
      P A Andrews, D E Brenner, F T Chou, H Kubo and N R Bachur
      Drug Metabolism and Disposition May 1980, 8 (3) 152-156; DOI: https://doi.org/10.1124/dmd.8.3.152
  2. Bigler, P

    1. You have access
      Identification of mephenytoin metabolites in the dog.
      G Karlaganis, A Küpfer, J Bircher, U P Schlunegger, H Gfeller and P Bigler
      Drug Metabolism and Disposition May 1980, 8 (3) 173-177; DOI: https://doi.org/10.1124/dmd.8.3.173
  3. Bindel, U

    1. You have access
      Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
      M D Golan, M Bücker, H U Schmassmann, D Raphael, R Jung, U Bindel, H O Brase, F Tegtmeyer, T Friedberg, J Lorenz, P Stasiecki and F Oesch
      Drug Metabolism and Disposition May 1980, 8 (3) 121-126; DOI: https://doi.org/10.1124/dmd.8.3.121
  4. Bircher, J

    1. You have access
      Identification of mephenytoin metabolites in the dog.
      G Karlaganis, A Küpfer, J Bircher, U P Schlunegger, H Gfeller and P Bigler
      Drug Metabolism and Disposition May 1980, 8 (3) 173-177; DOI: https://doi.org/10.1124/dmd.8.3.173
  5. Brase, H O

    1. You have access
      Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
      M D Golan, M Bücker, H U Schmassmann, D Raphael, R Jung, U Bindel, H O Brase, F Tegtmeyer, T Friedberg, J Lorenz, P Stasiecki and F Oesch
      Drug Metabolism and Disposition May 1980, 8 (3) 121-126; DOI: https://doi.org/10.1124/dmd.8.3.121
  6. Brenner, D E

    1. You have access
      Facile and definitive determination of human adriamycin and daunoribicin metabolites by high-pressure liquid chromatography.
      P A Andrews, D E Brenner, F T Chou, H Kubo and N R Bachur
      Drug Metabolism and Disposition May 1980, 8 (3) 152-156; DOI: https://doi.org/10.1124/dmd.8.3.152
  7. Bücker, M

    1. You have access
      Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
      M D Golan, M Bücker, H U Schmassmann, D Raphael, R Jung, U Bindel, H O Brase, F Tegtmeyer, T Friedberg, J Lorenz, P Stasiecki and F Oesch
      Drug Metabolism and Disposition May 1980, 8 (3) 121-126; DOI: https://doi.org/10.1124/dmd.8.3.121

C

  1. Chou, F T

    1. You have access
      Facile and definitive determination of human adriamycin and daunoribicin metabolites by high-pressure liquid chromatography.
      P A Andrews, D E Brenner, F T Chou, H Kubo and N R Bachur
      Drug Metabolism and Disposition May 1980, 8 (3) 152-156; DOI: https://doi.org/10.1124/dmd.8.3.152

D

  1. Davies, R O

    1. You have access
      The metabolic disposition of (S)-2-(3-tert-butylamino-2-hydroxypropoxy)-3-cyanopyridine in rats, dogs, and humans.
      S Vickers, C A Duncan, B H Arison, R O Davies, R Ferguson and A G Zacchei
      Drug Metabolism and Disposition May 1980, 8 (3) 163-167; DOI: https://doi.org/10.1124/dmd.8.3.163
  2. Deeb, G

    1. You have access
      Disposition of 14C-cefatrizine in man.
      R C Gaver and G Deeb
      Drug Metabolism and Disposition May 1980, 8 (3) 157-162; DOI: https://doi.org/10.1124/dmd.8.3.157
  3. Duncan, C A

    1. You have access
      The metabolic disposition of (S)-2-(3-tert-butylamino-2-hydroxypropoxy)-3-cyanopyridine in rats, dogs, and humans.
      S Vickers, C A Duncan, B H Arison, R O Davies, R Ferguson and A G Zacchei
      Drug Metabolism and Disposition May 1980, 8 (3) 163-167; DOI: https://doi.org/10.1124/dmd.8.3.163

F

  1. Ferguson, R

    1. You have access
      The metabolic disposition of (S)-2-(3-tert-butylamino-2-hydroxypropoxy)-3-cyanopyridine in rats, dogs, and humans.
      S Vickers, C A Duncan, B H Arison, R O Davies, R Ferguson and A G Zacchei
      Drug Metabolism and Disposition May 1980, 8 (3) 163-167; DOI: https://doi.org/10.1124/dmd.8.3.163
  2. Friedberg, T

    1. You have access
      Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
      M D Golan, M Bücker, H U Schmassmann, D Raphael, R Jung, U Bindel, H O Brase, F Tegtmeyer, T Friedberg, J Lorenz, P Stasiecki and F Oesch
      Drug Metabolism and Disposition May 1980, 8 (3) 121-126; DOI: https://doi.org/10.1124/dmd.8.3.121

G

  1. Gaver, R C

    1. You have access
      Disposition of 14C-cefatrizine in man.
      R C Gaver and G Deeb
      Drug Metabolism and Disposition May 1980, 8 (3) 157-162; DOI: https://doi.org/10.1124/dmd.8.3.157
  2. Gfeller, H

    1. You have access
      Identification of mephenytoin metabolites in the dog.
      G Karlaganis, A Küpfer, J Bircher, U P Schlunegger, H Gfeller and P Bigler
      Drug Metabolism and Disposition May 1980, 8 (3) 173-177; DOI: https://doi.org/10.1124/dmd.8.3.173
  3. Golan, M D

    1. You have access
      Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
      M D Golan, M Bücker, H U Schmassmann, D Raphael, R Jung, U Bindel, H O Brase, F Tegtmeyer, T Friedberg, J Lorenz, P Stasiecki and F Oesch
      Drug Metabolism and Disposition May 1980, 8 (3) 121-126; DOI: https://doi.org/10.1124/dmd.8.3.121
  4. Gruber, V

    1. You have access
      Identification of a glutathione conjugate of cambendazole formed in the presence of liver microsomes.
      D E Wolf, J A VandenHeuvel, T R Tyler, R W Walker, F R Koniuszy, V Gruber, B H Arison, A Rosegay, T A Jacob and F J Wolf
      Drug Metabolism and Disposition May 1980, 8 (3) 131-136; DOI: https://doi.org/10.1124/dmd.8.3.131

H

  1. Harvey, D J

    1. You have access
      Identification of in vivo liver metabolites of delta 6-tetrahydrocannabinol produced by the mouse.
      D J Harvey and W D Paton
      Drug Metabolism and Disposition May 1980, 8 (3) 178-186; DOI: https://doi.org/10.1124/dmd.8.3.178

J

  1. Jacob, T A

    1. You have access
      Identification of a glutathione conjugate of cambendazole formed in the presence of liver microsomes.
      D E Wolf, J A VandenHeuvel, T R Tyler, R W Walker, F R Koniuszy, V Gruber, B H Arison, A Rosegay, T A Jacob and F J Wolf
      Drug Metabolism and Disposition May 1980, 8 (3) 131-136; DOI: https://doi.org/10.1124/dmd.8.3.131
  2. Jung, R

    1. You have access
      Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
      M D Golan, M Bücker, H U Schmassmann, D Raphael, R Jung, U Bindel, H O Brase, F Tegtmeyer, T Friedberg, J Lorenz, P Stasiecki and F Oesch
      Drug Metabolism and Disposition May 1980, 8 (3) 121-126; DOI: https://doi.org/10.1124/dmd.8.3.121

K

  1. Karlaganis, G

    1. You have access
      Identification of mephenytoin metabolites in the dog.
      G Karlaganis, A Küpfer, J Bircher, U P Schlunegger, H Gfeller and P Bigler
      Drug Metabolism and Disposition May 1980, 8 (3) 173-177; DOI: https://doi.org/10.1124/dmd.8.3.173
  2. Koniuszy, F R

    1. You have access
      Identification of a glutathione conjugate of cambendazole formed in the presence of liver microsomes.
      D E Wolf, J A VandenHeuvel, T R Tyler, R W Walker, F R Koniuszy, V Gruber, B H Arison, A Rosegay, T A Jacob and F J Wolf
      Drug Metabolism and Disposition May 1980, 8 (3) 131-136; DOI: https://doi.org/10.1124/dmd.8.3.131
  3. Kubo, H

    1. You have access
      Facile and definitive determination of human adriamycin and daunoribicin metabolites by high-pressure liquid chromatography.
      P A Andrews, D E Brenner, F T Chou, H Kubo and N R Bachur
      Drug Metabolism and Disposition May 1980, 8 (3) 152-156; DOI: https://doi.org/10.1124/dmd.8.3.152
  4. Küpfer, A

    1. You have access
      Identification of mephenytoin metabolites in the dog.
      G Karlaganis, A Küpfer, J Bircher, U P Schlunegger, H Gfeller and P Bigler
      Drug Metabolism and Disposition May 1980, 8 (3) 173-177; DOI: https://doi.org/10.1124/dmd.8.3.173

L

  1. Lorenz, J

    1. You have access
      Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
      M D Golan, M Bücker, H U Schmassmann, D Raphael, R Jung, U Bindel, H O Brase, F Tegtmeyer, T Friedberg, J Lorenz, P Stasiecki and F Oesch
      Drug Metabolism and Disposition May 1980, 8 (3) 121-126; DOI: https://doi.org/10.1124/dmd.8.3.121

M

  1. Martz, F

    1. You have access
      Metabolism and covalent binding of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane (o,p,'-DDD). Correlation between adrenocorticolytic activity and metabolic activation by adrenocortical mitochondria.
      F Martz and J A Straw
      Drug Metabolism and Disposition May 1980, 8 (3) 127-130; DOI: https://doi.org/10.1124/dmd.8.3.127
  2. Masters, B S

    1. You have access
      Effect of phenobarbital treatment and cytochrome P-450 inhibitors on the laurate omega- and (omega - 1)-hydroxylase activities of rat liver microsomes.
      R T Okita and B S Masters
      Drug Metabolism and Disposition May 1980, 8 (3) 147-151; DOI: https://doi.org/10.1124/dmd.8.3.147

O

  1. Oesch, F

    1. You have access
      Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
      M D Golan, M Bücker, H U Schmassmann, D Raphael, R Jung, U Bindel, H O Brase, F Tegtmeyer, T Friedberg, J Lorenz, P Stasiecki and F Oesch
      Drug Metabolism and Disposition May 1980, 8 (3) 121-126; DOI: https://doi.org/10.1124/dmd.8.3.121
  2. Okita, R T

    1. You have access
      Effect of phenobarbital treatment and cytochrome P-450 inhibitors on the laurate omega- and (omega - 1)-hydroxylase activities of rat liver microsomes.
      R T Okita and B S Masters
      Drug Metabolism and Disposition May 1980, 8 (3) 147-151; DOI: https://doi.org/10.1124/dmd.8.3.147
  3. Olson, J W

    1. You have access
      Inhibition of hepatic drug metabolism in VX2 carcinoma-bearing rabbits.
      M Weiner and J W Olson
      Drug Metabolism and Disposition May 1980, 8 (3) 139-142; DOI: https://doi.org/10.1124/dmd.8.3.139

P

  1. Paton, W D

    1. You have access
      Identification of in vivo liver metabolites of delta 6-tetrahydrocannabinol produced by the mouse.
      D J Harvey and W D Paton
      Drug Metabolism and Disposition May 1980, 8 (3) 178-186; DOI: https://doi.org/10.1124/dmd.8.3.178

R

  1. Raphael, D

    1. You have access
      Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
      M D Golan, M Bücker, H U Schmassmann, D Raphael, R Jung, U Bindel, H O Brase, F Tegtmeyer, T Friedberg, J Lorenz, P Stasiecki and F Oesch
      Drug Metabolism and Disposition May 1980, 8 (3) 121-126; DOI: https://doi.org/10.1124/dmd.8.3.121
  2. Roche, E B

    1. You have access
      Effect of acute and chronic estrone, estradiol, and estriol treatment on hepatic, pulmonary, and intestinal mixed-function mon-oxygenase activities in female rats.
      W A Al-Turk, S J Stohs and E B Roche
      Drug Metabolism and Disposition May 1980, 8 (3) 143-146; DOI: https://doi.org/10.1124/dmd.8.3.143
  3. Rosegay, A

    1. You have access
      Identification of a glutathione conjugate of cambendazole formed in the presence of liver microsomes.
      D E Wolf, J A VandenHeuvel, T R Tyler, R W Walker, F R Koniuszy, V Gruber, B H Arison, A Rosegay, T A Jacob and F J Wolf
      Drug Metabolism and Disposition May 1980, 8 (3) 131-136; DOI: https://doi.org/10.1124/dmd.8.3.131
    2. You have access
      4-Thio derivatives of cambendazole.
      A Rosegay
      Drug Metabolism and Disposition May 1980, 8 (3) 136-138; DOI: https://doi.org/10.1124/dmd.8.3.136

S

  1. Schlunegger, U P

    1. You have access
      Identification of mephenytoin metabolites in the dog.
      G Karlaganis, A Küpfer, J Bircher, U P Schlunegger, H Gfeller and P Bigler
      Drug Metabolism and Disposition May 1980, 8 (3) 173-177; DOI: https://doi.org/10.1124/dmd.8.3.173
  2. Schmassmann, H U

    1. You have access
      Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
      M D Golan, M Bücker, H U Schmassmann, D Raphael, R Jung, U Bindel, H O Brase, F Tegtmeyer, T Friedberg, J Lorenz, P Stasiecki and F Oesch
      Drug Metabolism and Disposition May 1980, 8 (3) 121-126; DOI: https://doi.org/10.1124/dmd.8.3.121
  3. Sporn, M B

    1. You have access
      Pharmacokinetics of N-(4-hydroxyphenyl)-all-trans-retinamide in rats.
      B N Swanson, D W Zaharevitz and M B Sporn
      Drug Metabolism and Disposition May 1980, 8 (3) 168-172; DOI: https://doi.org/10.1124/dmd.8.3.168
  4. Stasiecki, P

    1. You have access
      Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
      M D Golan, M Bücker, H U Schmassmann, D Raphael, R Jung, U Bindel, H O Brase, F Tegtmeyer, T Friedberg, J Lorenz, P Stasiecki and F Oesch
      Drug Metabolism and Disposition May 1980, 8 (3) 121-126; DOI: https://doi.org/10.1124/dmd.8.3.121
  5. Stohs, S J

    1. You have access
      Effect of acute and chronic estrone, estradiol, and estriol treatment on hepatic, pulmonary, and intestinal mixed-function mon-oxygenase activities in female rats.
      W A Al-Turk, S J Stohs and E B Roche
      Drug Metabolism and Disposition May 1980, 8 (3) 143-146; DOI: https://doi.org/10.1124/dmd.8.3.143
  6. Straw, J A

    1. You have access
      Metabolism and covalent binding of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane (o,p,'-DDD). Correlation between adrenocorticolytic activity and metabolic activation by adrenocortical mitochondria.
      F Martz and J A Straw
      Drug Metabolism and Disposition May 1980, 8 (3) 127-130; DOI: https://doi.org/10.1124/dmd.8.3.127
  7. Swanson, B N

    1. You have access
      Pharmacokinetics of N-(4-hydroxyphenyl)-all-trans-retinamide in rats.
      B N Swanson, D W Zaharevitz and M B Sporn
      Drug Metabolism and Disposition May 1980, 8 (3) 168-172; DOI: https://doi.org/10.1124/dmd.8.3.168

T

  1. Tegtmeyer, F

    1. You have access
      Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
      M D Golan, M Bücker, H U Schmassmann, D Raphael, R Jung, U Bindel, H O Brase, F Tegtmeyer, T Friedberg, J Lorenz, P Stasiecki and F Oesch
      Drug Metabolism and Disposition May 1980, 8 (3) 121-126; DOI: https://doi.org/10.1124/dmd.8.3.121
  2. Tyler, T R

    1. You have access
      Identification of a glutathione conjugate of cambendazole formed in the presence of liver microsomes.
      D E Wolf, J A VandenHeuvel, T R Tyler, R W Walker, F R Koniuszy, V Gruber, B H Arison, A Rosegay, T A Jacob and F J Wolf
      Drug Metabolism and Disposition May 1980, 8 (3) 131-136; DOI: https://doi.org/10.1124/dmd.8.3.131

V

  1. VandenHeuvel, J A

    1. You have access
      Identification of a glutathione conjugate of cambendazole formed in the presence of liver microsomes.
      D E Wolf, J A VandenHeuvel, T R Tyler, R W Walker, F R Koniuszy, V Gruber, B H Arison, A Rosegay, T A Jacob and F J Wolf
      Drug Metabolism and Disposition May 1980, 8 (3) 131-136; DOI: https://doi.org/10.1124/dmd.8.3.131
  2. Vickers, S

    1. You have access
      The metabolic disposition of (S)-2-(3-tert-butylamino-2-hydroxypropoxy)-3-cyanopyridine in rats, dogs, and humans.
      S Vickers, C A Duncan, B H Arison, R O Davies, R Ferguson and A G Zacchei
      Drug Metabolism and Disposition May 1980, 8 (3) 163-167; DOI: https://doi.org/10.1124/dmd.8.3.163

W

  1. Walker, R W

    1. You have access
      Identification of a glutathione conjugate of cambendazole formed in the presence of liver microsomes.
      D E Wolf, J A VandenHeuvel, T R Tyler, R W Walker, F R Koniuszy, V Gruber, B H Arison, A Rosegay, T A Jacob and F J Wolf
      Drug Metabolism and Disposition May 1980, 8 (3) 131-136; DOI: https://doi.org/10.1124/dmd.8.3.131
  2. Weiner, M

    1. You have access
      Inhibition of hepatic drug metabolism in VX2 carcinoma-bearing rabbits.
      M Weiner and J W Olson
      Drug Metabolism and Disposition May 1980, 8 (3) 139-142; DOI: https://doi.org/10.1124/dmd.8.3.139
  3. Wolf, D E

    1. You have access
      Identification of a glutathione conjugate of cambendazole formed in the presence of liver microsomes.
      D E Wolf, J A VandenHeuvel, T R Tyler, R W Walker, F R Koniuszy, V Gruber, B H Arison, A Rosegay, T A Jacob and F J Wolf
      Drug Metabolism and Disposition May 1980, 8 (3) 131-136; DOI: https://doi.org/10.1124/dmd.8.3.131
  4. Wolf, F J

    1. You have access
      Identification of a glutathione conjugate of cambendazole formed in the presence of liver microsomes.
      D E Wolf, J A VandenHeuvel, T R Tyler, R W Walker, F R Koniuszy, V Gruber, B H Arison, A Rosegay, T A Jacob and F J Wolf
      Drug Metabolism and Disposition May 1980, 8 (3) 131-136; DOI: https://doi.org/10.1124/dmd.8.3.131

Z

  1. Zacchei, A G

    1. You have access
      The metabolic disposition of (S)-2-(3-tert-butylamino-2-hydroxypropoxy)-3-cyanopyridine in rats, dogs, and humans.
      S Vickers, C A Duncan, B H Arison, R O Davies, R Ferguson and A G Zacchei
      Drug Metabolism and Disposition May 1980, 8 (3) 163-167; DOI: https://doi.org/10.1124/dmd.8.3.163
  2. Zaharevitz, D W

    1. You have access
      Pharmacokinetics of N-(4-hydroxyphenyl)-all-trans-retinamide in rats.
      B N Swanson, D W Zaharevitz and M B Sporn
      Drug Metabolism and Disposition May 1980, 8 (3) 168-172; DOI: https://doi.org/10.1124/dmd.8.3.168
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Drug Metabolism and Disposition
Vol. 8, Issue 3
1 May 1980
  • Table of Contents
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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