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Drug Metabolism & Disposition

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Table of Contents

March 01, 1981; Volume 9,Issue 2
  • You have access
    Renal N-oxidation of meperidine by the perfused kidney of the rat.
    M Acara, T Gessner, H Greizerstein and R Trudnowski
    Drug Metabolism and Disposition March 1981, 9 (2) 75-79;
  • You have access
    Uptake of anticoagulants by isolated rat hepatocytes.
    W D Wosilait, M P Ryan and K H Byington
    Drug Metabolism and Disposition March 1981, 9 (2) 80-84;
  • You have access
    Sulfoxide reduction. In vitro reduction of sulindac by rat hepatic cytosolic enzymes.
    J H Ratnayake, P E Hanna, M W Anders and D E Duggan
    Drug Metabolism and Disposition March 1981, 9 (2) 85-87;
  • You have access
    Metabolism of 2-methylnaphthalene to isomeric dihydrodiols by hepatic microsomes of rat and rainbow trout.
    R K Breger, R B Franklin and J J Lech
    Drug Metabolism and Disposition March 1981, 9 (2) 88-93;
  • You have access
    Metabolic pathways for the transformation of delta 1-tetrahydrocannabinol in mouse hepatic microsomes.
    S Burstein and T S Shoupe
    Drug Metabolism and Disposition March 1981, 9 (2) 94-96;
  • You have access
    The effect of phenobarbital and beta-naphthoflavone induction on the metabolism of biphenyl in the rat and mouse.
    K Halpaap-Wood, E C Horning and M G Horning
    Drug Metabolism and Disposition March 1981, 9 (2) 97-102;
  • You have access
    The effect of 3-methylcholanthrene, Aroclor 1254, and phenobarbital induction on the metabolism of biphenyl by rat and mouse 9000g supernatant liver fractions.
    K Halpaap-Wood, E C Horning and M G Horning
    Drug Metabolism and Disposition March 1981, 9 (2) 103-107;
  • You have access
    Biotransformation of lisuride in the hemoglobin-free perfused rat liver and in the whole animal.
    T Toda and N Oshino
    Drug Metabolism and Disposition March 1981, 9 (2) 108-113;
  • You have access
    Metabolism of piroxicam by laboratory animals.
    D C Hobbs and T M Twomey
    Drug Metabolism and Disposition March 1981, 9 (2) 114-118;
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    Disposition of furobufen in mice, rats, dogs, and man.
    M N Cayen, M Kraml, W T Robinson and D Dvornik
    Drug Metabolism and Disposition March 1981, 9 (2) 119-124;
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    Distribution and excretion of furobufen in rats and dogs.
    M N Cayen, E S Ferdinandi and E Greselin
    Drug Metabolism and Disposition March 1981, 9 (2) 125-128;
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    Ethynyl cleavage of 17 alpha-ethynylestradiol in the rhesus monkey.
    L A Raitano, W Slikker, D E Hill, H E Hadd, T Cairns and E D Helton
    Drug Metabolism and Disposition March 1981, 9 (2) 129-134;
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    Urinary metabolites of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea.
    S J Kohlhepp, H E May and D J Reed
    Drug Metabolism and Disposition March 1981, 9 (2) 135-141;
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    The isolation and identification of 14C-sulfamethazine (4-amino-n-(4,6-dimethyl-2-pyrimidinyl)[14C]benzenesulfonamide) metabolites in the tissues and excreta of swine.
    G D Paulson, J M Giddings, C H Lamoureux, E R Mansager and C B Struble
    Drug Metabolism and Disposition March 1981, 9 (2) 142-146;
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    Dipeptide conjugation of 3-phenoxybenzoic acid in the mallard duck.
    K R Huckle, I J Climie, D H Hutson and P Millburn
    Drug Metabolism and Disposition March 1981, 9 (2) 147-149;
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    The metabolism and kinetics of tiflorex in the rat.
    C Mas-Chamberlin, G Gillet, J André, R Gomeni, L G Dring and P L Morselli
    Drug Metabolism and Disposition March 1981, 9 (2) 150-155;
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    Metabolism of ethidium bromide in rats.
    C Fraire, P Lecointe and C Paoletti
    Drug Metabolism and Disposition March 1981, 9 (2) 156-160;
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    The disposition and metabolism of 5-(4,5-dihydro-2-phenylbenz[e]indol-3-yl)salicylic acid (fendosal) in the rat, mouse, rabbit, do, rhesus monkey, and man.
    A Warrander, R Metcalf and J M Fromson
    Drug Metabolism and Disposition March 1981, 9 (2) 161-167;
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    Influence of mixed-function oxidase inducers on the in vitro metabolism of N'-nitrosonornicotine by rat and hamster liver microsomes.
    G D McCoy, C B Chen and S S Hecht
    Drug Metabolism and Disposition March 1981, 9 (2) 168-169;
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    The effect of pregnancy and lactation on the elimination of methadone in guinea pigs.
    R C Pak and D J Ecobichon
    Drug Metabolism and Disposition March 1981, 9 (2) 170-171;
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    An added complication in the estimation of apparent hepatic blood flow in vivo by pharmacokinetic parameters.
    V J Stella, K Yamaoka and R H Levy
    Drug Metabolism and Disposition March 1981, 9 (2) 172-173;
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In this issue

Drug Metabolism and Disposition
Vol. 9, Issue 2
1 Mar 1981
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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