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Drug Metabolism & Disposition

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Table of Contents

July 01, 1981; Volume 9,Issue 4
  • You have access
    Thioredoxin-dependent sulfoxide reduction by rat renal cytosol.
    M W Anders, J H Ratnayake, P E Hanna and J A Fuchs
    Drug Metabolism and Disposition July 1981, 9 (4) 307-310;
  • You have access
    Drug metabolism in skin. Comparative activity of the mixed-function oxidases, epoxide hydratase, and glutathione S-transferase in liver and skin of the neonatal rat.
    H Mukhtar and D R Bickers
    Drug Metabolism and Disposition July 1981, 9 (4) 311-314;
  • You have access
    Mixed-function oxygenation of the lower fatty acyl residues. II. The kinetics of microsomal omega- and (omega - 1)-hydroxylation of N-(4-chlorophenyl)propanamide.
    V Apostolescu and W Lenk
    Drug Metabolism and Disposition July 1981, 9 (4) 315-321;
  • You have access
    Species and dose differences in the accumulation of imipramine by mammalian lungs.
    R Drew, Z H Siddik, E G Mimnaugh and T E Gram
    Drug Metabolism and Disposition July 1981, 9 (4) 322-326;
  • You have access
    Effect of tamoxifen treatment on liver, lung and intestinal mixed-function oxidases in male and female rats.
    W A Al-Turk, S J Stohs and E B Roche
    Drug Metabolism and Disposition July 1981, 9 (4) 327-330;
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    The biodistribution and metabolic fate of inhaled 11C-octanal in the rat after acute exposure.
    R S Kutzman, G J Meyer, A P Wolf and T Akasaka
    Drug Metabolism and Disposition July 1981, 9 (4) 331-333;
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    The formation of diglutathionyl dithiocarbonate as a metabolite of chloroform, bromotrichloromethane, and carbon tetrachloride.
    L R Pohl, R V Branchflower, R J Highet, J L Martin, D S Nunn, T J Monks, J W George and J A Hinson
    Drug Metabolism and Disposition July 1981, 9 (4) 334-339;
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    Formation and disposition of the minor metabolites of acetaminophen in the hamster.
    M W Gemborys and G H Mudge
    Drug Metabolism and Disposition July 1981, 9 (4) 340-351;
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    Species differences in the metabolism of 3-phenoxybenzoic acid.
    K R Huckle, D H Hutson and P Millburn
    Drug Metabolism and Disposition July 1981, 9 (4) 352-359;
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    Metabolism of 3-phenoxybenzoic acid and the enterohepatorenal disposition of its metabolites in the rat.
    K R Huckle, J K Chipman, D H Hutson and P Millburn
    Drug Metabolism and Disposition July 1981, 9 (4) 360-368;
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    Metabolism and disposition of naltrexone in man after oral and intravenous administration.
    M E Wall, D R Brine and M Perez-Reyes
    Drug Metabolism and Disposition July 1981, 9 (4) 369-375;
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    Quantitative determination of the urinary excretion of ketobemidone and four of its metabolites after intravenous and oral administration in man.
    U Bondesson, P Hartvig and B Danielsson
    Drug Metabolism and Disposition July 1981, 9 (4) 376-380;
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    Qualitative and quantitative studies of methylphenobarbital metabolism in man.
    W D Hooper, H E Kunze and M J Eadie
    Drug Metabolism and Disposition July 1981, 9 (4) 381-385;
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    Tissue distribution of n-hexane, methyl n-butyl ketone, and 2,5-hexanedione in rats after single or repeated inhalation exposure to n-hexane.
    J S Bus, E L White, P J Gillies and C S Barrow
    Drug Metabolism and Disposition July 1981, 9 (4) 386-387;
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    Is a photo-oxidation product of histidine one of the triggers of induction of cytochrome P-450 drug-metabolizing enzyme systems?
    P G Dayton and Z H Israili
    Drug Metabolism and Disposition July 1981, 9 (4) 391;
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In this issue

Drug Metabolism and Disposition
Vol. 9, Issue 4
1 Jul 1981
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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