More articles from Article

Open Access
Metabolism and Mass Balance of the Novel Nonsteroidal Androgen Receptor Inhibitor Darolutamide in Humans
Päivi Taavitsainen, Olaf Prien, Marja Kähkönen, Michael Niehues, Timo Korjamo, Karsten Denner, Pirjo Nykänen, Annamari Vuorela, Natalia A. Jungmann, Clemens-Jeremias von Bühler, Mikko Koskinen, Christian Zurth and Hille Gieschen

Drug Metabolism and Disposition June 2021, 49 (6) 420-433; DOI: https://doi.org/10.1124/dmd.120.000309
You have access
Dual Action of Acidic Microenvironment on the Enrichment of the Active Metabolite of Disulfiram in Tumor Tissues
Chongzhuang Tang, Xiaoyan Pang, Zitao Guo, Runcong Guo, Lu Liu and Xiaoyan Chen

Drug Metabolism and Disposition June 2021, 49 (6) 434-441; DOI: https://doi.org/10.1124/dmd.120.000317
You have access
Multiple Computational Approaches for Predicting Drug Interactions with Human Equilibrative Nucleoside Transporter 1
Siennah R. Miller, Thomas R. Lane, Kimberley M. Zorn, Sean Ekins, Stephen H. Wright and Nathan Cherrington

Drug Metabolism and Disposition May 12, 2021, DMD-AR-2021-000423; DOI: https://doi.org/10.1124/dmd.121.000423
You have access
Hepatic Scaling Factors for In Vitro-In Vivo Extrapolation (IVIVE) of Metabolic Drug Clearance in Patients with Colorectal Cancer with Liver Metastasis
Areti-Maria Vasilogianni, Brahim Achour, Daniel Scotcher, Sheila Annie Peters, Zubida M. Al-Majdoub, Jill Barber and Amin Rostami-Hodjegan

Drug Metabolism and Disposition May 12, 2021, DMD-AR-2021-000359; DOI: https://doi.org/10.1124/dmd.121.000359
You have access
A new intestinal model for analysis of drug absorption and interactions considering physiological translocation of contents
Satoshi Asano, Aoi Yoshitomo, Shizuka Hozuki, Hiromi Sato, Yasuhiro Kazuki and Akihiro Hisaka

Drug Metabolism and Disposition May 7, 2021, DMD-AR-2021-000361; DOI: https://doi.org/10.1124/dmd.121.000361
You have access
Improving the Translation of Organic Anion Transporting Polypeptide Substrates using HEK293 Cell Data in the Presence and Absence of Human Plasma via PBPK Modeling
Christine M. Bowman, Buyun Chen, Jonathan Cheong, Liling Liu, Yuan Chen and Jialin Mao

Drug Metabolism and Disposition May 6, 2021, DMD-AR-2020-000315; DOI: https://doi.org/10.1124/dmd.120.000315
You have access
Development and verification of a linked ᵪB;⁹-THC/11-OH-THC physiologically-based pharmacokinetic (PBPK) model in healthy, non-pregnant population and extrapolation to pregnant women
Gabriela I. Patilea-Vrana and Jashvant D. Unadkat

Drug Metabolism and Disposition May 5, 2021, DMD-AR-2020-000322; DOI: https://doi.org/10.1124/dmd.120.000322
You have access
Evaluation of the Absorption, Metabolism, and Excretion of a Single Oral 1 mg Dose of Tropifexor in Healthy Male Subjects and the Concentration Dependency of Tropifexor Metabolism
Lydia Wang-Lakshman, Zhuang Miao, Lai Wang, Helen Gu, Mark Kagan, Jessie Gu, Elizabeth McNamara, Markus Walles, Ralph Woessner, Gian Camenisch, Heidi J. Einolf and Jin Chen

Drug Metabolism and Disposition May 5, 2021, DMD-AR-2020-000349; DOI: https://doi.org/10.1124/dmd.120.000349
You have access
Comparative proteomics analysis of the post-mitochondrial supernatant fraction of human lens-free whole eye and liver
Ankit Balhara, Abdul Basit, Upendra A. Argikar, Jennifer L. Dumouchel, Saranjit Singh and Bhagwat Prasad

Drug Metabolism and Disposition May 5, 2021, DMD-AR-2020-000297; DOI: https://doi.org/10.1124/dmd.120.000297
You have access
Nonclinical Pharmacokinetics and ADME of Givosiran, the First Approved GalNAc-conjugated RNAi Therapeutic
Jing Li, Ju Liu, Xuemei Zhang, Valerie Clausen, Chris Tran, Michael Arciprete, Qianfan Wang, Carrie Rocca, Li-Hua Guan, Guodong Zhang, Diana Najarian, Yuanxin Xu, Peter Smith, Jing-Tao Wu and Saeho Chong

Drug Metabolism and Disposition May 4, 2021, DMD-AR-2021-000381; DOI: https://doi.org/10.1124/dmd.121.000381

Main menu

User menu

Search

More articles from Article

Pages

Navigate

More Information

ASPET's Other Journals