More articles from Article

You have access
Pharmacokinetic/pharmacodynamic models of an Alzheimer's drug, donepezil, in rats
Akiko Kiriyama, Shunsuke Kimura and Shugo Yamashita

Drug Metabolism and Disposition December 7, 2022, DMD-AR-2022-001061; DOI: https://doi.org/10.1124/dmd.122.001061
You have access
Contribution of UGT enzymes to human drug metabolism stereoselectivity: a case study of medetomidine, RO5263397, propranolol and testosterone
Nicolò Milani, NaHong Qiu and Stephen Fowler

Drug Metabolism and Disposition December 7, 2022, DMD-AR-2022-001024; DOI: https://doi.org/10.1124/dmd.122.001024
You have access
Assessing Liver-to-Plasma Partition Coefficients and In Silico Calculation Methods: When Does the Hepatic Model Matter in PBPK?
Xiaonan Li and William J. Jusko

Drug Metabolism and Disposition December 2022, 50 (12) 1501-1512; DOI: https://doi.org/10.1124/dmd.122.000994
You have access
Comprehensive analyses of the intracellular and in vivo disposition of Fab-siRNA conjugate to identify key issues to improve its in vivo activity
Asami Toshima, Yasuhisa Shiraishi, Daisuke Shinmi, Yoshiyuki Kagawa and Junichi Enokizono

Drug Metabolism and Disposition December 2, 2022, DMD-AR-2022-001098; DOI: https://doi.org/10.1124/dmd.122.001098
You have access
Intravital microscopy reveals unforeseen biodistribution within the liver and kidney mechanistically connected to the clearance of a bifunctional antibody
Amita Datta-Mannan, Bruce A. Molitoris, Yiqing Feng, Michelle M. Martinez, Ruben M. Sandoval, Robin M Brown, Daniel Merkel, Johnny E. Croy and Kenneth W. Dunn

Drug Metabolism and Disposition December 2, 2022, DMD-AR-2022-001049; DOI: https://doi.org/10.1124/dmd.122.001049
You have access
Quantitative CYP3A4 induction risk assessment using human hepatocytes complemented with pregnane X receptor (PXR)-activating profiles
Aynur Ekiciler, Wen Li Kelly Chen, Yan Bo, Alessandra Pugliano, Massimiliano Donzelli, Neil Parrott and Kenichi Umehara

Drug Metabolism and Disposition December 2, 2022, DMD-AR-2022-001132; DOI: https://doi.org/10.1124/dmd.122.001132
You have access
Maternal and Fetal Exposure to (-)-Δ⁹-tetrahydrocannabinol and Its Major Metabolites in Pregnant Mice Is Differentially Impacted by P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP)
Xin Chen, Jashvant D. Unadkat and Qingcheng Mao

Drug Metabolism and Disposition November 29, 2022, DMD-AR-2022-001110; DOI: https://doi.org/10.1124/dmd.122.001110
You have access
Quantification of accurate composition and total abundance of homologous proteins by conserved-plus-surrogate peptide (CPSP) approach: Quantification of UDP glucuronosyltransferases in human tissues
Deepak Ahire, Mitesh Patel, Sujal V Deshmukh and Bhagwat Prasad

Drug Metabolism and Disposition November 29, 2022, DMD-AR-2022-001155; DOI: https://doi.org/10.1124/dmd.122.001155
You have access
Hydroxychloroquine is metabolized by CYP2D6, CYP3A4, and CYP2C8, and inhibits CYP2D6, while its metabolites also inhibit CYP3A in vitro
Marie-Noëlle Paludetto, Mika Kurkela, Helinä Kahma, Janne T. Backman, Mikko Niemi and Anne M. Filppula

Drug Metabolism and Disposition November 29, 2022, DMD-AR-2022-001018; DOI: https://doi.org/10.1124/dmd.122.001018
You have access
Dimethandrolone, a Potential Male Contraceptive Pill, is Primarily Metabolized by the Highly Polymorphic UDP-Glucuronosyltransferase 2B17 Enzyme in Human Intestine and Liver
Sheena Sharma, Deepak Ahire, Abdul Basit, Maria Lajoie, Christina Wang, Min S. Lee, Diana L. Blithe, John K. Amory, Dilip K. Singh, Scott Heyward and Bhagwat Prasad

Drug Metabolism and Disposition December 2022, 50 (12) 1493-1500; DOI: https://doi.org/10.1124/dmd.122.001041

Main menu

User menu

Search

More articles from Article

Pages

Navigate

More Information

ASPET's Other Journals