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Drug Metabolism & Disposition

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More articles from Special Section – New Models in Drug Metabolism and Transport

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    Microfluidic Cell Culture Platforms to Capture Hepatic Physiology and Complex Cellular Interactions
    Shyam Sundhar Bale and Jeffrey T. Borenstein
    Drug Metabolism and Disposition November 2018, 46 (11) 1638-1646; DOI: https://doi.org/10.1124/dmd.118.083055
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    Models and Approaches Describing the Metabolism, Transport, and Toxicity of Drugs Administered by the Ocular Route
    Jennifer L. Dumouchel, Nagendra Chemuturi, Mark N. Milton, Gian Camenisch, James Chastain, Markus Walles, Vito Sasseville, Mithat Gunduz, Ganesh R. Iyer and Upendra A. Argikar
    Drug Metabolism and Disposition November 2018, 46 (11) 1670-1683; DOI: https://doi.org/10.1124/dmd.118.082974
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    Emerging Models of Drug Metabolism, Transporters, and Toxicity
    Aarti Sawant-Basak and R. Scott Obach
    Drug Metabolism and Disposition November 2018, 46 (11) 1556-1561; DOI: https://doi.org/10.1124/dmd.118.084293
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    Perspective on the Application of Microphysiological Systems to Drug Transporter Studies
    Pedro Caetano-Pinto and Simone H. Stahl
    Drug Metabolism and Disposition November 2018, 46 (11) 1647-1657; DOI: https://doi.org/10.1124/dmd.118.082750
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    Assessment of the Biotransformation of Low-Turnover Drugs in the HµREL Human Hepatocyte Coculture Model
    Richard D. Burton, Todd Hieronymus, Taysir Chamem, David Heim, Shelby Anderson, Xiaochun Zhu and J. Matthew Hutzler
    Drug Metabolism and Disposition November 2018, 46 (11) 1617-1625; DOI: https://doi.org/10.1124/dmd.118.082867
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    Humanized UGT1 Mice, Regulation of UGT1A1, and the Role of the Intestinal Tract in Neonatal Hyperbilirubinemia and Breast Milk-Induced Jaundice
    Shujuan Chen and Robert H. Tukey
    Drug Metabolism and Disposition November 2018, 46 (11) 1745-1755; DOI: https://doi.org/10.1124/dmd.118.083212
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    Advances in Engineered Human Liver Platforms for Drug Metabolism Studies
    Gregory H. Underhill and Salman R. Khetani
    Drug Metabolism and Disposition November 2018, 46 (11) 1626-1637; DOI: https://doi.org/10.1124/dmd.118.083295
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    Human Pluripotent Stem Cell–Derived Kidney Model for Nephrotoxicity Studies
    Piyush Bajaj, A. David Rodrigues, Claire M. Steppan, Sandra J. Engle, Sumathy Mathialagan and Thomas Schroeter
    Drug Metabolism and Disposition November 2018, 46 (11) 1703-1711; DOI: https://doi.org/10.1124/dmd.118.082727
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    Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier
    Yamato Sano, Tadahaya Mizuno, Tatsuki Mochizuki, Yasuo Uchida, Mina Umetsu, Tetsuya Terasaki and Hiroyuki Kusuhara
    Drug Metabolism and Disposition November 2018, 46 (11) 1767-1775; DOI: https://doi.org/10.1124/dmd.118.081877
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    Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells
    Daichi Onozato, Misaki Yamashita, Anna Nakanishi, Takumi Akagawa, Yuriko Kida, Isamu Ogawa, Tadahiro Hashita, Takahiro Iwao and Tamihide Matsunaga
    Drug Metabolism and Disposition November 2018, 46 (11) 1572-1580; DOI: https://doi.org/10.1124/dmd.118.080374

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