More articles from Special Section – New Models in Drug Metabolism and Transport

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Assessment of the Biotransformation of Low-Turnover Drugs in the HµREL Human Hepatocyte Coculture Model
Richard D. Burton, Todd Hieronymus, Taysir Chamem, David Heim, Shelby Anderson, Xiaochun Zhu and J. Matthew Hutzler

Drug Metabolism and Disposition November 2018, 46 (11) 1617-1625; DOI: https://doi.org/10.1124/dmd.118.082867
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Humanized UGT1 Mice, Regulation of UGT1A1, and the Role of the Intestinal Tract in Neonatal Hyperbilirubinemia and Breast Milk-Induced Jaundice
Shujuan Chen and Robert H. Tukey

Drug Metabolism and Disposition November 2018, 46 (11) 1745-1755; DOI: https://doi.org/10.1124/dmd.118.083212
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Advances in Engineered Human Liver Platforms for Drug Metabolism Studies
Gregory H. Underhill and Salman R. Khetani

Drug Metabolism and Disposition November 2018, 46 (11) 1626-1637; DOI: https://doi.org/10.1124/dmd.118.083295
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Human Pluripotent Stem Cell–Derived Kidney Model for Nephrotoxicity Studies
Piyush Bajaj, A. David Rodrigues, Claire M. Steppan, Sandra J. Engle, Sumathy Mathialagan and Thomas Schroeter

Drug Metabolism and Disposition November 2018, 46 (11) 1703-1711; DOI: https://doi.org/10.1124/dmd.118.082727
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Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier
Yamato Sano, Tadahaya Mizuno, Tatsuki Mochizuki, Yasuo Uchida, Mina Umetsu, Tetsuya Terasaki and Hiroyuki Kusuhara

Drug Metabolism and Disposition November 2018, 46 (11) 1767-1775; DOI: https://doi.org/10.1124/dmd.118.081877
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Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells
Daichi Onozato, Misaki Yamashita, Anna Nakanishi, Takumi Akagawa, Yuriko Kida, Isamu Ogawa, Tadahiro Hashita, Takahiro Iwao and Tamihide Matsunaga

Drug Metabolism and Disposition November 2018, 46 (11) 1572-1580; DOI: https://doi.org/10.1124/dmd.118.080374
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Porcine Prediction of Pharmacokinetic Parameters in People: A Pig in a Poke?
Huadong Tang and Michael Mayersohn

Drug Metabolism and Disposition November 2018, 46 (11) 1712-1724; DOI: https://doi.org/10.1124/dmd.118.083311
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How to Determine the Role of the Microbiome in Drug Disposition
Jordan E. Bisanz, Peter Spanogiannopoulos, Lindsey M. Pieper, Annamarie E. Bustion and Peter J. Turnbaugh

Drug Metabolism and Disposition November 2018, 46 (11) 1588-1595; DOI: https://doi.org/10.1124/dmd.118.083402
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Characterization of P-Glycoprotein Humanized Mice Generated by Chromosome Engineering Technology: Its Utility for Prediction of Drug Distribution to the Brain in Humans
Yuki Yamasaki, Kaoru Kobayashi, Fuka Okuya, Naoyo Kajitani, Kanako Kazuki, Satoshi Abe, Shoko Takehara, Shingo Ito, Seiryo Ogata, Tatsuki Uemura, Sumio Ohtsuki, Genki Minegishi, Hidetaka Akita, Kan Chiba, Mitsuo Oshimura and Yasuhiro Kazuki

Drug Metabolism and Disposition November 2018, 46 (11) 1756-1766; DOI: https://doi.org/10.1124/dmd.118.081216
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Pheophorbide A: Fluorescent Bcrp Substrate to Measure Oral Drug-Drug Interactions in Real-Time In Vivo
Kazuto Yasuda, Samit Ganguly and Erin G. Schuetz

Drug Metabolism and Disposition November 2018, 46 (11) 1725-1733; DOI: https://doi.org/10.1124/dmd.118.083584

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