More articles from Special Section on Pediatric Drug Disposition and Pharmacokinetics

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Predicting Stereoselective Disposition of Carvedilol in Adult and Pediatric Chronic Heart Failure Patients by Incorporating Pathophysiological Changes in Organ Blood Flows–A Physiologically Based Pharmacokinetic Approach
Muhammad Fawad Rasool, Feras Khalil and Stephanie Läer

Drug Metabolism and Disposition July 2016, 44 (7) 1103-1115; DOI: https://doi.org/10.1124/dmd.115.068858
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Population Pharmacokinetics of Oral Topotecan in Infants and Very Young Children with Brain Tumors Demonstrates a Role of ABCG2 rs4148157 on the Absorption Rate Constant
Jessica K. Roberts, Anna V. Birg, Tong Lin, Vinay M. Daryani, John C. Panetta, Alberto Broniscer, Giles W. Robinson, Amar J. Gajjar and Clinton F. Stewart

Drug Metabolism and Disposition July 2016, 44 (7) 1116-1122; DOI: https://doi.org/10.1124/dmd.115.068676
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Considering Age Variation When Coining Drugs as High versus Low Hepatic Extraction Ratio
Farzaneh Salem, Khaled Abduljalil, Yoshiteru Kamiyama and Amin Rostami-Hodjegan

Drug Metabolism and Disposition July 2016, 44 (7) 1099-1102; DOI: https://doi.org/10.1124/dmd.115.067595
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Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children
Jean C. Dinh, Robin E. Pearce, Leon Van Haandel, Andrea Gaedigk and J. Steven Leeder

Drug Metabolism and Disposition July 2016, 44 (7) 1070-1079; DOI: https://doi.org/10.1124/dmd.116.069518
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Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers
Gleb Martovetsky, Kevin T. Bush and Sanjay K. Nigam

Drug Metabolism and Disposition July 2016, 44 (7) 1050-1060; DOI: https://doi.org/10.1124/dmd.115.068254
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Dynamics of Cytosine Methylation in the Proximal Promoters of CYP3A4 and CYP3A7 in Pediatric and Prenatal Livers
Carrie A. Vyhlidal, Chengpeng Bi, Shui Qing Ye and J. Steven Leeder

Drug Metabolism and Disposition July 2016, 44 (7) 1020-1026; DOI: https://doi.org/10.1124/dmd.115.068726
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How Does In Vivo Biliary Elimination of Drugs Change with Age? Evidence from In Vitro and Clinical Data Using a Systems Pharmacology Approach
Trevor N. Johnson, Masoud Jamei and Karen Rowland-Yeo

Drug Metabolism and Disposition July 2016, 44 (7) 1090-1098; DOI: https://doi.org/10.1124/dmd.115.068643
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Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life
Miriam G. Mooij, Evita van de Steeg, Joost van Rosmalen, Jonathan D. Windster, Barbara A.E. de Koning, Wouter H. J. Vaes, Bianca D. van Groen, Dick Tibboel, Heleen M. Wortelboer and Saskia N. de Wildt

Drug Metabolism and Disposition July 2016, 44 (7) 1005-1013; DOI: https://doi.org/10.1124/dmd.115.068577
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Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver
Margaret M. S. Thomson, Ronald N. Hines, Erin G. Schuetz and Bernd Meibohm

Drug Metabolism and Disposition July 2016, 44 (7) 999-1004; DOI: https://doi.org/10.1124/dmd.115.069252
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Examining Small Intestinal Transit Time as a Function of Age: Is There Evidence to Support Age-Dependent Differences among Children?
Anil R. Maharaj and Andrea N. Edginton

Drug Metabolism and Disposition July 2016, 44 (7) 1080-1089; DOI: https://doi.org/10.1124/dmd.115.068700

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