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Drug Metabolism & Disposition

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More articles from Special Section on Pediatric Drug Disposition and Pharmacokinetics

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    Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants
    Miriam G. Mooij, Barbara E. A. de Koning, Dicky J. Lindenbergh-Kortleve, Ytje Simons-Oosterhuis, Bianca D. van Groen, Dick Tibboel, Janneke N. Samsom and Saskia N. de Wildt
    Drug Metabolism and Disposition July 2016, 44 (7) 1014-1019; DOI: https://doi.org/10.1124/dmd.115.068809
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    Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation
    Robin E. Pearce, Roger Gaedigk, Greyson P. Twist, Hongying Dai, Amanda K. Riffel, J. Steven Leeder and Andrea Gaedigk
    Drug Metabolism and Disposition July 2016, 44 (7) 948-958; DOI: https://doi.org/10.1124/dmd.115.067546
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    The Ontogeny and Population Variability of Human Hepatic NADPH Dehydrogenase Quinone Oxido-Reductase 1 (NQO1)
    Luc R.A. Rougée, Zoe Riches, Jacob M. Berman and Abby C. Collier
    Drug Metabolism and Disposition July 2016, 44 (7) 967-974; DOI: https://doi.org/10.1124/dmd.115.068650
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    Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny
    Yao Chen, Nicole R. Zane, Dhiren R. Thakker and Michael Zhuo Wang
    Drug Metabolism and Disposition July 2016, 44 (7) 975-983; DOI: https://doi.org/10.1124/dmd.115.067538
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    Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny
    Ronald N. Hines, Pippa M. Simpson and D. Gail McCarver
    Drug Metabolism and Disposition July 2016, 44 (7) 959-966; DOI: https://doi.org/10.1124/dmd.115.068957
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    Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children
    Jean C. Dinh, Robin E. Pearce, Leon Van Haandel, Andrea Gaedigk and J. Steven Leeder
    Drug Metabolism and Disposition July 2016, 44 (7) 1070-1079; DOI: https://doi.org/10.1124/dmd.116.069518
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    Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers
    Gleb Martovetsky, Kevin T. Bush and Sanjay K. Nigam
    Drug Metabolism and Disposition July 2016, 44 (7) 1050-1060; DOI: https://doi.org/10.1124/dmd.115.068254
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    Dynamics of Cytosine Methylation in the Proximal Promoters of CYP3A4 and CYP3A7 in Pediatric and Prenatal Livers
    Carrie A. Vyhlidal, Chengpeng Bi, Shui Qing Ye and J. Steven Leeder
    Drug Metabolism and Disposition July 2016, 44 (7) 1020-1026; DOI: https://doi.org/10.1124/dmd.115.068726
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    How Does In Vivo Biliary Elimination of Drugs Change with Age? Evidence from In Vitro and Clinical Data Using a Systems Pharmacology Approach
    Trevor N. Johnson, Masoud Jamei and Karen Rowland-Yeo
    Drug Metabolism and Disposition July 2016, 44 (7) 1090-1098; DOI: https://doi.org/10.1124/dmd.115.068643

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